Piliocolobus tephrosceles (Ugandan red Colobus): 111520730
Help
Entry
111520730 CDS
T07491
Symbol
DOT1L
Name
(RefSeq) histone-lysine N-methyltransferase, H3 lysine-79 specific isoform X1
KO
K11427
[histone H3]-lysine79 N-trimethyltransferase [EC:
2.1.1.360
]
Organism
pteh
Piliocolobus tephrosceles (Ugandan red Colobus)
Pathway
pteh00310
Lysine degradation
pteh01100
Metabolic pathways
pteh05202
Transcriptional misregulation in cancer
Brite
KEGG Orthology (KO) [BR:
pteh00001
]
09100 Metabolism
09105 Amino acid metabolism
00310 Lysine degradation
111520730 (DOT1L)
09160 Human Diseases
09161 Cancer: overview
05202 Transcriptional misregulation in cancer
111520730 (DOT1L)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
pteh03036
]
111520730 (DOT1L)
Enzymes [BR:
pteh01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.360 [histone H3]-lysine79 N-trimethyltransferase
111520730 (DOT1L)
Chromosome and associated proteins [BR:
pteh03036
]
Eukaryotic type
Histone modification proteins
HMTs (histone methyltransferases)
HKMTs (histone lysine methyltransferases)
111520730 (DOT1L)
HMT complexes
Dot1-containing complex
111520730 (DOT1L)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
DOT1
Motif
Other DBs
NCBI-GeneID:
111520730
NCBI-ProteinID:
XP_023039493
Ensembl:
ENSPTEG00000027980
LinkDB
All DBs
Position
21:complement(50587634..50664550)
Genome browser
AA seq
1537 aa
AA seq
DB search
MGEKLELRLKSPVGAEPAVYPWPLPVYDKHHDAAHEIIETIRWVCEEIPDLKLAMENYVL
IDYDTKSFESMQRLCDKYNRAIDSIHQLWKGTTQPMKLNTRPSTGLLRHILQQVYNHSVT
DPEKLNNYEPFSPEVYGETSFDLVAQMIDEIKMTDDDLFVDLGSGVGQVVLQVAAATNCK
HHYGVEKADIPAKYAETMDREFRKWMKWYGKKHAEYTLERGDFLSEEWRERIANTSVIFV
NNFAFGPEVDHQLKERFANMKEGGRIVSSKPFAPLNFRINSRNLSDIGTIMRVVELSPLK
GSVSWTGKPVSYYLHTIDRTILENYFSSLKNPKLREEQEAARRRQQRESKSNAATPTKGP
EGKLAGPTDAPMDSGAEEEKAGAAAVKKPSPSKARKKKLNKKGRKMAGRKRGRPKKMSTA
NPERKPKKNQTALDVLHAQTVSQTAASSPQDAYRSPHSPFYQLPPSVQRHSPNPLLVAPT
PPALQKLLESFKIQYLQFLAYTKTPQYKASLQELLGQEKEKNTQLLGAAQQLLSHCQAQK
EEIRRLFQQKLDELGVKALTYNDLIQAQKEISAHNQQLREQSEQLEQDNRALRSQSLQLL
KARCEELQLDWATLSLEKLLKEKQALKSQISEKQRHCLELQISIVELEKSQRQQELLQLK
SCVPPDDALSLHLRGKGALGRELEPDASRLHLELDCAKFSLPHLSSMSPELSMNGQAAGY
ELCSALSRPSSKQNTPQYLASPLDQEVVPCTPSHGGRPRLEKLSGLAAPDYTRLSPAKIV
LRRHLSQDHTVPGRPATSELHPRAEHTKENGLPYQSPSVPGSMKLSPQDPRPLSPGALQL
AGEKSSEKGLRERAHGGGGELITSLPISIPLSTVQPNKLPVSIPLASVVLPSRAERARST
PSPVLQPRDPSSTLEKQIGANAHGAGSRSLALAPAGFSYAGSVAISGALAGSPASLTPGA
EPATLDESSSSGSLFATVGSRSSTPQHPLLLAQPRNSLPASPAHQLSSSPRLGGAAQGPL
TEASKGDLPSDSGFSDPESEAKRRIVFTIATGAGSAKQSPSSKHSPLTASARGDCVPSHG
QDSRKRGRRKRASTGTPSLSTGVSPKRRALPSVAGLFTQPSGSPLNLNSMVSNINQPLEI
TAISSPETSLKSSPVPYQDHDQPPVLKKERPLSQTNGAHYSPLTSDEEPGSEDEPSSARI
ERKIATISLESKSPPKTLENGGGLAGRKPTPASEPVNSSKWKSTFSPISDIGLAKSADSP
LQASSALSQNSLFTFRPALEEPPADAKLATHPRKGFPSSLSGADGLSPSTNPANGCTFGG
GLAADLSLHSFSDGASLPHKGPEAASLSSPLSFPSQRGKEASDANPFLSKRQLDGLAGLK
GEGSRSKEAGEGGLQLCGPTDKTPLLTSKAAKARDRELDLKNGHNLFISAAAVPPGSLLS
GPGLAPVASSTGGAASSTQTHRPFLGPFPPGPQFALGPMSLQANLGSVAGSSVLQSLFSS
VPAAAGLVHVSSAATRLTNSHAMGSFSGVAGSTVGGN
NT seq
4614 nt
NT seq
+upstream
nt +downstream
nt
atgggggagaagctggagctgagactcaagtcgcccgtgggggctgagcccgccgtctac
ccgtggccgttgccggtctacgacaaacatcacgatgctgctcatgaaatcatcgagacc
atccgatgggtctgtgaagaaatcccggatctcaagctcgctatggagaattacgtttta
attgactatgacaccaaaagcttcgagagcatgcagaggctctgcgacaagtacaaccgc
gccatcgatagcatccaccagctgtggaagggcaccacgcagcccatgaagctgaacacg
cggccgtccaccgggctcctgcgccacatcctgcagcaggtctacaaccactcggtgact
gaccccgagaagctcaacaactacgagcccttctcccctgaggtgtacggggagacctcc
ttcgacctggtggcccagatgattgacgagatcaagatgaccgacgacgacctgtttgtg
gacttggggagcggtgtgggccaggtcgtgctccaggtcgccgctgccaccaactgcaaa
catcactatggcgtcgagaaagcagacatcccggccaagtatgcagagaccatggaccgc
gagttcaggaagtggatgaaatggtatggaaaaaagcatgcagaatacacattggagaga
ggcgatttcctctcagaagagtggagggagcgaatcgccaacacgagtgttatatttgtg
aataattttgcctttggtcctgaggtggatcaccagctgaaggagcggtttgcaaacatg
aaggaaggtggcagaatcgtgtcctcgaaaccctttgcacctctgaacttcagaataaac
agtagaaacttgagtgacatcggcaccatcatgcgcgtggtggagctgtcgcccctgaag
ggctcggtgtcgtggacagggaagccggtctcctactacctgcacactatcgaccgcacc
atacttgaaaactatttttctagtctgaaaaacccaaaactcagggaggaacaggaggca
gcccggcgccgccagcagcgcgagagcaagagcaacgcggccacgcccaccaagggcccc
gagggcaagctggcaggccccaccgacgcccccatggactctggtgctgaggaagagaag
gcgggagcagccgccgtgaagaagccgtctccctccaaagcccgcaagaagaagctcaac
aagaaggggaggaagatggctggccgcaagcgcgggcgccccaagaagatgagcactgcg
aaccccgagcggaagcccaagaagaaccaaactgcactggatgtcctgcacgctcagacc
gtgtctcagacggcagcctcctcgccccaggatgcctacaggtcccctcacagcccgttc
taccagctacctccgagcgtgcagcggcactcccccaacccgctgctggtggcgcccacc
ccgcccgcgttgcagaagctgctagagtctttcaagatccagtacctgcagttcctggca
tacacaaagaccccccagtacaaggccagcctgcaggagctgctgggccaggagaaggag
aagaacacccagctcctgggcgcggctcagcagctcctcagccactgccaggcccagaag
gaggagatcaggaggctgttccagcaaaaattggatgagctgggcgtgaaggcgctgacc
tacaacgacctgattcaggcgcagaaggagatctccgcccacaaccagcagctgcgggaa
cagtcggagcagctggagcaggacaaccgtgcgctgcgcagccagagcttgcagctgctc
aaggctcgctgcgaggagctgcagctggactgggccacgctgtccctggagaagctgctg
aaggagaagcaggccctgaagagccagatctcggagaagcagaggcactgcctggagctg
cagatcagcatcgtggagctggagaagagccagcggcagcaggagctcctgcagctcaag
tcctgtgtgccgcctgatgacgccctgtctctgcacctacgcgggaagggggccctgggc
cgcgagctggagcctgacgccagccggctgcacctggagctggactgtgccaagttctcg
ctgcctcacttgagcagcatgagcccagagctctccatgaacggccaggctgccggctat
gagctctgcagtgcgctgagccggccctcgtccaagcagaacacaccccagtacctggcc
tcacccctagaccaggaggtggtgccctgcacccccagccacggcggccggccacgcctg
gagaagctgtctggcctggctgcacccgactacaccaggctgtccccggccaagattgtg
ctgaggcggcacctgagccaggaccacacggtgcccggcaggccggccaccagcgagctg
cacccgagagctgagcacaccaaggagaacggccttccctaccagagccccagcgtgcct
ggcagcatgaagctgagtccccaggacccgcggcccctgtcacctggggccttgcagctt
gctggagagaagagcagtgagaagggcctgagagagcgcgcccacggcggcggcggggag
ctcatcaccagcctgcccatcagcatcccgctgagcaccgtgcagcccaacaagctcccg
gtcagcatccccctggccagcgtggtgctgcccagccgcgccgagagggcgaggagcacc
cccagtcccgtgctgcagccccgcgacccctcgtccacacttgaaaagcagattggtgct
aatgcccacggtgctgggagcagaagccttgccctggccccagcaggcttctcctacgct
ggctctgtggccatcagcggggccttggcgggcagcccggcctctctcacacctggagct
gagccggccaccttggatgagtcctccagctctgggagcctttttgccactgtggggtcc
cgcagctccacaccacagcaccccttgctgctggcacagccccggaactcgctcccggcc
tctcccgcccaccagctctcctccagcccccggcttggtggggctgcccagggcccgctc
accgaggccagcaagggggacttgccctcagattccggtttctcagatcctgagagtgag
gccaagaggaggatcgtgtttaccatcgccactggtgcgggcagtgccaaacagtcgccc
tccagcaagcatagccccctgaccgccagcgcccgtggggactgcgtgccgagccacggg
caggacagccgcaagcgcgggcggcggaagcgagcgtcgacggggacacccagcttgagc
acaggcgtgtcccccaagcgccgagccctgccgtctgtcgctggccttttcacacaacct
tcagggtctcccctcaacctcaactccatggtcagtaacatcaaccagcccctggagatt
acagccatctcgtcccccgagacctccctgaagagctcccctgtgccctaccaagaccac
gaccagccccccgtgctcaagaaggagcggcctctgagccagaccaatggggcacactac
tccccgctcacctcggacgaggagccaggctctgaggacgagcccagcagcgcccgaatt
gagagaaaaattgcaacaatctccttagaaagcaaatctcccccgaaaaccttggaaaat
ggtggtggtttggcgggaaggaagcccacgcccgcgagcgagccagtcaacagcagcaag
tggaagtcgactttctcgcccatctcagacatcggcctggccaagtctgcagacagcccg
ctgcaggccagctctgccctcagccagaactccctgttcacgttccggcctgccctggag
gagccccctgccgatgccaagctggccacccaccccaggaaaggctttcccagctctctg
tcgggggctgacggactcagcccgagcaccaaccctgccaacggctgcacctttggcggg
ggcctggccgcggacctgagtttacacagcttcagcgatggtgcttctcttccccacaag
ggccccgaggcggccagcctgagctccccgctgagcttcccctcgcagcgcggcaaggag
gcctcggacgccaaccctttcctgagcaagaggcagctggacggcctggctgggctgaag
ggcgagggcagccgcagcaaggaggcaggggagggcggcctgcagctgtgcgggcccacg
gacaagaccccgctgctgaccagcaaggccgccaaggcccgagaccgcgagctcgacctc
aagaatggccacaacctcttcatctccgctgcggccgtgcctcccggaagcctcctcagc
ggccccggcctggccccggtggcgtcctccacaggtggcgcggcatcctccacccagacg
caccggcccttcttgggccccttcccgccgggaccgcagtttgcgcttggccccatgtcc
ctgcaggccaacctcggctccgtggccggctcctccgtgctgcagtcgctgttcagctct
gtgccggccgccgcaggcctggtgcacgtgtcatccgctgccaccagactgaccaactcg
cacgccatgggcagcttttccggggtggcaggcagcacagttggaggtaactag
DBGET
integrated database retrieval system
