Piliocolobus tephrosceles (Ugandan red Colobus): 111527746
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Entry
111527746 CDS
T07491
Symbol
TYK2
Name
(RefSeq) non-receptor tyrosine-protein kinase TYK2
KO
K11219
non-receptor tyrosine-protein kinase TYK2 [EC:
2.7.10.2
]
Organism
pteh
Piliocolobus tephrosceles (Ugandan red Colobus)
Pathway
pteh04217
Necroptosis
pteh04380
Osteoclast differentiation
pteh04620
Toll-like receptor signaling pathway
pteh04621
NOD-like receptor signaling pathway
pteh04630
JAK-STAT signaling pathway
pteh04658
Th1 and Th2 cell differentiation
pteh04659
Th17 cell differentiation
pteh05145
Toxoplasmosis
pteh05160
Hepatitis C
pteh05161
Hepatitis B
pteh05162
Measles
pteh05164
Influenza A
pteh05165
Human papillomavirus infection
pteh05167
Kaposi sarcoma-associated herpesvirus infection
pteh05168
Herpes simplex virus 1 infection
pteh05169
Epstein-Barr virus infection
pteh05171
Coronavirus disease - COVID-19
Brite
KEGG Orthology (KO) [BR:
pteh00001
]
09130 Environmental Information Processing
09132 Signal transduction
04630 JAK-STAT signaling pathway
111527746 (TYK2)
09140 Cellular Processes
09143 Cell growth and death
04217 Necroptosis
111527746 (TYK2)
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
111527746 (TYK2)
04621 NOD-like receptor signaling pathway
111527746 (TYK2)
04658 Th1 and Th2 cell differentiation
111527746 (TYK2)
04659 Th17 cell differentiation
111527746 (TYK2)
09158 Development and regeneration
04380 Osteoclast differentiation
111527746 (TYK2)
09160 Human Diseases
09172 Infectious disease: viral
05161 Hepatitis B
111527746 (TYK2)
05160 Hepatitis C
111527746 (TYK2)
05171 Coronavirus disease - COVID-19
111527746 (TYK2)
05164 Influenza A
111527746 (TYK2)
05162 Measles
111527746 (TYK2)
05168 Herpes simplex virus 1 infection
111527746 (TYK2)
05167 Kaposi sarcoma-associated herpesvirus infection
111527746 (TYK2)
05169 Epstein-Barr virus infection
111527746 (TYK2)
05165 Human papillomavirus infection
111527746 (TYK2)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
111527746 (TYK2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
pteh01001
]
111527746 (TYK2)
Enzymes [BR:
pteh01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
111527746 (TYK2)
Protein kinases [BR:
pteh01001
]
Non-receptor tyrosine kinases
JAK family [OT]
111527746 (TYK2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
SH2_1
Kinase-like
FERM_F1
Kdo
RIO1
ABC1
Motif
Other DBs
NCBI-GeneID:
111527746
NCBI-ProteinID:
XP_031790585
LinkDB
All DBs
Position
21:42544569..42576748
Genome browser
AA seq
877 aa
AA seq
DB search
MPLRHRGMTRGSKPVGDGAQPMAAMGGLKVLLHWAGPGGGEPWVAFSESSLTAEEVCIHI
AHKVGESGALAPWGLGWVCEQQLGPIHPSVHPSIRPPLHPPNHPSVHPPVCACCCAVSPC
NECHCSRVWVQQWPKWPDSPPGSPSREPFVQAKLRPEDGLYLIHWSTSHPYRLILTVAQR
SQAPDGTQSLRLRKFPIEQQAGAFVLEGWGRSFPSIRELGAALQGCLLRAGDDCFSLRRC
CLPQPGETSNLIIMRGARASTRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRV
EGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHVHL
AFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNL
VHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERIPWMAPECLPGGPNS
LSIAMDKWGFGATLLEICFDGEAPLQSRSSSEKEHFYQRQHRLPEPSCPELATLTSQCLT
YEPTQRPSFRTILRDLTRLQPHNLADVLIVNPDSSASDPTVFHKRYLKKIRDLGEGHFGK
VSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIEILRTLSHEHIVKYKGCCEDQG
EKSLQLVMEYVPLGSLRDYLPRHSVGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVL
LDNDKLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVT
LYELLTHCDSSQSPPTKFLELIGITQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKN
CWETEASFRPTFENLIPILKTVHEKYQGQAPSVFSVC
NT seq
2634 nt
NT seq
+upstream
nt +downstream
nt
atgcctttgcgccatcgggggatgaccaggggcagcaagcccgttggggatggagcccag
cccatggctgccatgggaggcctgaaggtgcttctgcactgggctggtccaggcggcgga
gagccctgggtcgctttcagcgagtcatcgctgacagctgaggaagtctgcatccacatt
gcacataaagttggtgagtctggggcactggcaccatggggactggggtgggtgtgcgag
cagcagctgggccccatccatccatccgtccacccatctatccgcccacctctccaccca
cctaatcatccatccgtccacccacccgtatgtgcctgctgctgcgctgtgtctccatgt
aatgagtgtcattgttcccgggtatgggtccagcagtggcccaagtggcctgatagtccc
cctggatccccttccagggagccgtttgtgcaggccaagctgcggcccgaggacggcctg
tacctcattcactggagcaccagccacccctaccgcctgatcctcacagtggcccagcgt
agccaggcaccagacggcacacagagcttgcggctccggaagttccccattgagcagcag
gccggggcctttgtgctggagggctggggccggtccttccccagcattcgggaacttggg
gctgccttgcagggctgcttgctgagggccggggacgactgcttctctctgcgtcgctgt
tgcctgccccaaccaggagaaacctccaacctcatcatcatgcggggggctcgagccagc
accaggacactcaacctcagccagctcagcttccaccgggttgaccagaaggagatcacc
cagctgtcccacttgggccagggcacaaggaccaacgtgtacgagggccgcctgcgagtg
gagggcagtggggaccctgaggagggcaagatggacgacgaggaccccctcgtccctggc
agggaccgtgggcaggagctacgagtggtgctcaaagtgctggacccgagtcaccatgac
atcgccctggccttctatgagacagccagcctcatgagccaggtctcccacgtgcacctg
gccttcgtgcacggcgtctgtgtgcgaggccctgaaaatatcatggtgacagagtacgtg
gagcatggacccctggacgtgtggctacggagggagcggggccatgtgcccatggcttgg
aagatggtggtggcccagcagctggccagcgccctcagctacctggagaacaagaacctg
gtacatggtaatgtgtgtggccggaacatcctgctggctcggctggggctggcagagggc
acgagccccttcatcaagctgagtgatcccggcgtgggcctgggcgccctctccagggag
gagcgggtggagcggatcccctggatggcccccgaatgcctcccaggtgggcccaacagc
ctaagcattgccatggataagtgggggtttggtgccaccctcctggagatctgctttgat
ggagaggcccctctgcagagccgcagctcctccgagaaggagcatttctaccagaggcag
caccggctgcccgagccctcctgcccagagctggccacactcaccagccagtgtctgacc
tatgagccaacccagaggccttcattccgcaccatcctgcgtgacctcacccggctgcag
ccccacaatcttgctgacgtcttgattgtgaacccggactcatcggcgtcagaccctacg
gttttccacaagcgctatttgaaaaagatccgagatctgggcgagggtcacttcggcaag
gtcagtttgtactgctacgatccgaccaacgacggcactggcgagatggtggcggtgaaa
gcccttaaggcagactgcggcccccagcaccgctcgggctggaagcaggagattgagatt
ctgcgtacgctctctcacgagcacatcgtcaagtacaagggctgctgcgaggaccaaggc
gagaagtcgctgcagctggtcatggagtacgtgcccctgggcagcctccgagactacctg
ccccggcacagcgtggggctggcccagctgctgctcttcgcccagcagatctgcgagggc
atggcctatctgcacgcgcagcactacatccaccgagacctagccgcgcgcaacgtgctg
ctggacaacgacaagctggtcaagatcggggactttggcctagccaaggccgtgcccgaa
ggccacgagtactaccgcgtgcgcgaggatggagacagccccgtgttctggtatgcccca
gagtgcctgaaggagtataagttctactatgcgtccgatgtctggtccttcggggtgacc
ctgtatgagctgctgacgcactgtgactccagccagagcccccccacgaaattccttgag
ctcataggcatcacccagggtcagatgacagttctgagactcaccgagttgctggaacga
ggggagaggctgccgcgacccgacaaatgtccctgtgaggtctatcatctcatgaagaac
tgctgggagacagaggcgtccttccgcccaaccttcgagaacctcatacccatcctgaag
acagtccatgagaagtaccaaggccaggccccttccgtgttcagtgtgtgctga
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