KEGG   Piliocolobus tephrosceles (Ugandan red Colobus): 111529691
Entry
111529691         CDS       T07491                                 
Name
(RefSeq) cholesterol side-chain cleavage enzyme, mitochondrial isoform X1
  KO
K00498  cholesterol monooxygenase (side-chain-cleaving) [EC:1.14.15.6]
Organism
pteh  Piliocolobus tephrosceles (Ugandan red Colobus)
Pathway
pteh00140  Steroid hormone biosynthesis
pteh01100  Metabolic pathways
pteh04913  Ovarian steroidogenesis
pteh04925  Aldosterone synthesis and secretion
pteh04927  Cortisol synthesis and secretion
pteh04934  Cushing syndrome
Module
pteh_M00107  Steroid hormone biosynthesis, cholesterol => pregnenolone => progesterone
Brite
KEGG Orthology (KO) [BR:pteh00001]
 09100 Metabolism
  09103 Lipid metabolism
   00140 Steroid hormone biosynthesis
    111529691
 09150 Organismal Systems
  09152 Endocrine system
   04913 Ovarian steroidogenesis
    111529691
   04925 Aldosterone synthesis and secretion
    111529691
   04927 Cortisol synthesis and secretion
    111529691
 09160 Human Diseases
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    111529691
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   00199 Cytochrome P450 [BR:pteh00199]
    111529691
Enzymes [BR:pteh01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.15  With reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.15.6  cholesterol monooxygenase (side-chain-cleaving)
     111529691
Cytochrome P450 [BR:pteh00199]
 Cytochrome P450, animal type
  CYP11 family
   111529691
SSDB
Motif
Pfam: p450
Other DBs
NCBI-GeneID: 111529691
NCBI-ProteinID: XP_023052412
Ensembl: ENSPTEG00000023389
UniProt: A0A8C9HSM7
LinkDB
Position
6:85605383..85635537
AA seq 521 aa
MLAKGLPSRSVLVKGCQTFLSAPRERLGHLRVPTSEGAGISTRSPRPFNEIPSPGDNGWL
NLYHFWRETGSHKVHLHHVQNFQKYGPIYREKLGNVESVYVIDPEDVALLFKSEGPNPER
FLIPPWVAYHQYYQRPIGVLLKKSAAWKKDRVALNQEVMAPETTKNFLPLLDAVSRDFVS
VLHRRIKKAGSGNFSGDISDDLFRFAFESITNVIFGERQGMLEEVVNPEAQRFIDAIYQM
FHTSVPMLNLPPDLFRLFRTKTWKDHVAAWDVIFSKADIYTENFHWELRQKGNVHHDYRG
ILYRLLGDSKMSFEDIKANVTEMLAGGVDTTSMTLQWHLYEMARNLKVQDMLRAEVLAAR
RQAQGDMATMLQLVPLLKASIKETLRLHPISVTLQRYLVNDLVLRGYMIPAKTLVQVAIY
ALGREPTFFFDPENFDPTRWLSKDKNVTYFRNLGFGWGVRQCLGRRIAELEMTIFLINML
ENFRVEIQHLSDVGTTFNLILMPEKPISFTFWPFNQEATQE
NT seq 1566 nt   +upstreamnt  +downstreamnt
atgctggccaagggtcttccctcacgctcagtcctggtcaaaggctgccagacctttctg
agtgcccccagggagagactggggcatctcagggtgcccaccagtgagggagctggcatc
tctactcgcagtcctcgccccttcaatgagatcccctctcctggtgacaatggctggcta
aacctgtaccatttctggagggagacaggctcacacaaagtccaccttcaccatgtccag
aatttccagaagtatggcccgatttacagggagaagctcggcaacgtggagtcggtttat
gtcatcgaccctgaagatgtggcccttctctttaagtccgagggccccaacccggaacga
ttcctcatcccgccctgggtcgcctatcaccaatattaccagagacccataggagtcctg
ttgaagaagtcagcagcctggaagaaagaccgggtggccctgaaccaggaggtgatggct
ccagagaccaccaagaactttttgcccctgttggatgcagtgtctcgggacttcgtcagt
gtcctgcacaggcgcatcaagaaagcaggctccggaaatttctcaggggacatcagtgat
gacctgttccgctttgcctttgagtccatcactaacgtcatttttggggagcgccagggg
atgctggaggaagtagtgaaccccgaggcccagcggttcattgatgccatctaccagatg
ttccacaccagcgtccccatgctcaaccttcccccagacctattccgtctgttcaggacc
aagacctggaaggaccatgtggccgcatgggacgtgattttcagtaaagctgacatatac
accgagaacttccactgggaattgagacagaaaggaaatgtgcaccatgattaccgtggc
atcctctacagactcctgggagacagcaagatgtcctttgaggacatcaaggccaatgtc
acagagatgctggcaggaggggtggacacgacgtccatgaccctgcagtggcacttgtac
gagatggcacgcaacctgaaggtgcaggatatgctgcgggcagaggtcttggctgcgcgg
cgccaggcccagggagacatggccacgatgctgcagctggtccccctcctcaaagccagc
atcaaggagacactgagacttcaccccatctccgtgaccctgcagagatatctcgtaaat
gacttggttcttcgaggttacatgattcctgccaagacactggtgcaggtggccatctat
gctctgggccgagagcccaccttcttcttcgacccggaaaattttgacccaacccgatgg
ctgagcaaagacaagaacgttacctacttccggaacttgggctttggctggggtgtgcgg
cagtgtctgggacggcggatcgccgagctagagatgaccatcttcctcatcaatatgctg
gagaacttcagagttgaaatccaacatctcagcgatgtgggcaccacattcaacctcatc
ctgatgcctgaaaagcccatctccttcaccttctggccctttaaccaggaagcaacccag
gagtga

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