Piliocolobus tephrosceles (Ugandan red Colobus): 111542532
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Entry
111542532 CDS
T07491
Symbol
ERN1
Name
(RefSeq) serine/threonine-protein kinase/endoribonuclease IRE1 isoform X1
KO
K08852
serine/threonine-protein kinase/endoribonuclease IRE1 [EC:
2.7.11.1
3.1.26.-]
Organism
pteh
Piliocolobus tephrosceles (Ugandan red Colobus)
Pathway
pteh04140
Autophagy - animal
pteh04141
Protein processing in endoplasmic reticulum
pteh04210
Apoptosis
pteh04932
Non-alcoholic fatty liver disease
pteh05010
Alzheimer disease
pteh05012
Parkinson disease
pteh05014
Amyotrophic lateral sclerosis
pteh05016
Huntington disease
pteh05017
Spinocerebellar ataxia
pteh05022
Pathways of neurodegeneration - multiple diseases
pteh05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
pteh00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04141 Protein processing in endoplasmic reticulum
111542532 (ERN1)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
111542532 (ERN1)
09143 Cell growth and death
04210 Apoptosis
111542532 (ERN1)
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
111542532 (ERN1)
05012 Parkinson disease
111542532 (ERN1)
05014 Amyotrophic lateral sclerosis
111542532 (ERN1)
05016 Huntington disease
111542532 (ERN1)
05017 Spinocerebellar ataxia
111542532 (ERN1)
05022 Pathways of neurodegeneration - multiple diseases
111542532 (ERN1)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
111542532 (ERN1)
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
111542532 (ERN1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
pteh01001
]
111542532 (ERN1)
Enzymes [BR:
pteh01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
111542532 (ERN1)
Protein kinases [BR:
pteh01001
]
Serine/threonine kinases: Other
IRE family
111542532 (ERN1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Pkinase
Ribonuc_2-5A
PK_Tyr_Ser-Thr
PQQ_2
PQQ
Pkinase_fungal
Kdo
APH
CytochromB561_N
Motif
Other DBs
NCBI-GeneID:
111542532
NCBI-ProteinID:
XP_023067831
Ensembl:
ENSPTEG00000010166
UniProt:
A0A8C9GXV6
LinkDB
All DBs
Position
16:complement(57849922..57941919)
Genome browser
AA seq
978 aa
AA seq
DB search
MPARRLLLLLLTLLLPGLGIFGSTSTVTLPETLLFVSTLDGSLHAVSKRTGSIKWTLKED
PVLQVPTHVEEPAFLPDPNDGSLYTLGSKNNEGLTKLPFTIPELVQASPCRSSDGILYMG
KKQDIWYVIDLLTGEKQQTLSSAFADSLCPSTSLLYLGRTEYTITMYDTKTRELRWNATY
FDYAASLPEDDMDYKMSHFVSNGDGLVVTVDSESGDVLWIQNYASPVVAFYVWQREGLRK
VMHINVAVETLRYLTFMSGEVGRITKWKYPFPKETEAKSKLTPTLYVGKYSTSLYASPSM
VHEGVAVVPRGSTLPLLEGPQTDGVTIGDKGECVITPSTDLKFDPGLKSKNKLNYLRNYW
LLIGHHETPLSASTKMLERFPNNLPKHRENVIPADSEKKSFEEVINLVDQTSENAPTTVS
RDVEEKPAHAPARPEAPVDSVLKDVATIILSTFLLIGWVAFIITYPLSMHQQQQLQHQQF
QKELEKIQLLQQQQQQLPFHPPGDTAQDGELLDTSGPYSESSGTSSPNTSPRASNHSLCS
GSSASKAGGSPSLEQDDGDEETSMVIVGKISFCPKDVLGHGAEGTIVYRGMFDNRDVAVK
RILPECFSFADREVQLLRESDEHPNVIRYFCTEKDRQFQYIAIELCAATLQEYVEQKDFA
HLGLEPITLLQQTTSGLAHLHSLNIVHRDLKPHNILISMPNAHGKIKAMISDFGLCKKLA
AGRHSFSRRSGVPGTEGWIAPEMLSEDCKENPTYTVDIFSAGCVFYYVISEGSHPFGKSL
QRQANILLGACSLECLHPEKHEDVIARELIEKMIAMDPQKRPSAKHVLKHPFFWSLEKQL
QFFQDVSDRIEKESLDGPIVKQLERGGRAVVKMDWRENITVPLQTDLRKFRTYKGGSVRD
LLRAMRNKKHHYRELPAEVRETLGSLPDDFVCYFTSRFPHLLAHTYRAMELCSHERLFQP
YYFHRPPEPQPPVTPDAL
NT seq
2937 nt
NT seq
+upstream
nt +downstream
nt
atgccggcccggcggctgctgctgctgctgctgacgctgctgctgcccggcctcgggatt
tttggaagtaccagcacagtgacacttcctgaaaccttgttgtttgtgtcaacgctggat
ggaagtttgcatgctgtcagcaagaggacaggctcaatcaaatggactttaaaagaagat
ccagtcctgcaggtcccaacgcatgtggaagagcctgcctttctcccagatcctaatgat
ggtagcctgtatacgcttggaagcaagaataatgaaggcctgacgaaacttccttttacc
atcccagaattggtgcaggcatccccgtgccggagttcagatggaatcctctacatgggt
aaaaagcaggacatctggtatgttattgacctcctgactggggagaagcagcagaccttg
tcatcagcctttgcagatagtctctgcccatcaacctctcttctgtatcttgggcgaaca
gaatacaccatcaccatgtacgacaccaaaacccgagagctccggtggaatgccacctac
tttgactatgcagcctcgctgcccgaggacgacatggactacaagatgtcccactttgtg
tccaatggtgatgggctggtggtgaccgtggacagtgaatctggggatgtcctgtggatc
caaaactacgcctcccctgtggtggccttttatgtctggcagcgggagggtctcaggaag
gtgatgcacatcaatgtcgctgtggagaccctgcgctatctgaccttcatgtctggggag
gtggggcgcatcaccaagtggaagtacccgttccccaaggagacagaggccaagagcaag
ctgacgcccactctgtatgttgggaaatactctaccagcctctatgcctctccctcaatg
gtacacgagggagttgctgttgtgccccgcggcagcacacttcctttgctggaagggccc
cagactgatggcgtcaccattggggacaagggggagtgtgtgatcacgcccagcacagac
ctcaagtttgaccccggactcaaaagcaagaacaagctcaactacttgaggaattactgg
cttctgataggccaccatgaaaccccactgtctgcgtctaccaagatgctggagagattc
cccaacaatctgcccaaacatcgggaaaatgtgattcctgctgattcagagaaaaagagc
tttgaggaagttatcaacctggttgaccagacttcagaaaacgcacccaccaccgtgtct
cgggatgtggaggagaagcccgcccatgcccctgcccggcccgaggcccccgtggactcc
gtgctcaaggatgtggccaccatcatcctgagcaccttcctgctgattggctgggtggcc
ttcatcatcacctaccccctgagcatgcatcagcagcagcagctccagcaccagcagttt
cagaaggaactggagaagattcagctcctgcagcagcagcagcagcagctgcccttccac
ccacctggagacacggctcaggacggcgagcttctggacacatctggcccatactcagag
agctcgggcaccagcagccccaacacgtcccccagggcctccaaccactcgctctgctcc
ggcagctctgcctccaaggctggcggcagcccctccctggaacaagacgacggagatgag
gaaaccagcatggtgatagttgggaaaatttccttctgtcccaaggacgtcctgggccac
ggagctgagggcacaattgtgtaccggggcatgtttgacaaccgtgatgtggccgtgaag
aggatcctccccgagtgttttagcttcgcagaccgtgaggtccagctgttgcgagaatca
gatgaacacccgaacgtgatccgctacttctgcacggagaaggaccggcaattccagtac
attgccatcgagctgtgtgcagccaccctgcaagagtatgtggagcagaaggactttgcg
catctcggcctggagcccatcaccttgctgcagcagaccacctcgggcctggcccacctt
cactccctcaacatcgttcacagagacctaaagccccacaacattctcatatccatgccc
aatgcacatggcaagatcaaggccatgatctctgactttggcctgtgcaagaagctggca
gcgggcaggcacagcttcagccgccgatctggggtgcctggcacagaaggctggatagct
ccagagatgctgagtgaagactgtaaggagaaccctacctacacggtggacatcttttct
gcaggctgcgtcttttactacgtgatctctgagggcagccacccttttggcaagtccctg
cagcggcaggccaacatcctcctgggtgcctgcagcctcgagtgcttgcacccagagaag
cacgaagacgtcattgcacgtgaattgatagagaagatgattgcgatggatcctcagaaa
cgcccctcagcgaagcacgtgctgaaacacccattcttctggagcctagagaagcagctc
cagttcttccaggacgtgagtgacagaatagaaaaggaatccctggatggcccgattgtg
aaacagctagagagaggcgggagagccgtggtgaagatggactggcgggagaacatcacc
gtccccctccagacagacctgcgtaaattcaggacctataaaggtggttctgtcagagat
ctcctccgagccatgagaaataagaagcaccactaccgggaactgcctgcagaggtgcgg
gagacactgggttccctccctgacgacttcgtgtgctacttcacgtctcgcttcccccac
ctcctcgcacacacctaccgggccatggagctgtgcagccacgagagactcttccagccc
tactacttccacaggcccccagagccccagcccccagtgactccagacgccctctga
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