Piliocolobus tephrosceles (Ugandan red Colobus): 111545897
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Entry
111545897 CDS
T07491
Symbol
FPGS
Name
(RefSeq) folylpolyglutamate synthase, mitochondrial isoform X1
KO
K01930
folylpolyglutamate synthase [EC:
6.3.2.17
]
Organism
pteh
Piliocolobus tephrosceles (Ugandan red Colobus)
Pathway
pteh00790
Folate biosynthesis
pteh01100
Metabolic pathways
pteh01240
Biosynthesis of cofactors
pteh01523
Antifolate resistance
pteh04981
Folate transport and metabolism
Brite
KEGG Orthology (KO) [BR:
pteh00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
111545897 (FPGS)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
111545897 (FPGS)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
111545897 (FPGS)
Enzymes [BR:
pteh01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.17 tetrahydrofolate synthase
111545897 (FPGS)
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_C
Motif
Other DBs
NCBI-GeneID:
111545897
NCBI-ProteinID:
XP_026312948
Ensembl:
ENSPTEG00000016234
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Position
14:complement(10693768..10705675)
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AA seq
588 aa
AA seq
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MSRARNHLRAALSLAAASARGVTTQVAAQRGLSAWPVPQEPSMEYQDAVRMLNTLQTNAG
YLEQVKRQRGDPQAQLEAMELYLARSGLQVEDLDRLNIIHVTGTKGKGSTCAFTECILRS
YGLKTGFFSSPHLVQVRERIRINGQPISPELFTKYFWRLYHRLEETKDGSCVSMPPYFRF
LTLMAFHVFLQEKVDLAVVEVGIGGAYDCTNIIRKPVVCGVSSLGIDHTSLLGDTVEKIA
WQKGGIFKRGVPAFTVLQPEGPLAVLRDRAQQISCPLYLCPTLEALEEGGPPLALGLEGE
HQRSNAALALQLAHCWLQRQDRHGAGELKASRPGLLWQLPLAPVFQPTSHMRLGLRNTEW
PGRTQVLRRGPLTWYLDGAHTPSSVQACVRWFRQALKGRERPSGSGPEVRVLLFNATGDR
DPVALLKLLQPCQFDYAVFCPNLTEVSSTGNADQQNFTVTLDQVLLRCLEHQQHWNHLDE
EQASPDLWSAPSPEPGGPTSLLLAPHPPHTCSASSLVFSCISHALQWISQGRDPVFQPPT
PLKGLLTHPVAHSGASVLHEAAAIHVLVTGSLHLVGGVLKLLEPALSQ
NT seq
1767 nt
NT seq
+upstream
nt +downstream
nt
atgtcgcgggcgcggaaccacctgcgcgccgctctatccctggcagcggcgtctgcgcgc
ggcgtaacgacccaggtcgcggcgcagcggggcttgagcgcgtggccggtgccgcaggag
cccagcatggagtaccaggatgccgtgcgcatgcttaataccctgcagaccaatgccggc
tacctggagcaggtgaagcgccagcggggtgacccccaggcacagctggaagccatggaa
ctgtacctggcacggagtgggctgcaggtggaggacttggaccggctgaacatcatccac
gtcactgggacgaaggggaagggctccacttgtgccttcacggaatgtatcctccgaagc
tatggcctgaagacgggattctttagctctccccacctggtgcaggttcgggagcggatc
cgcatcaatgggcagcccatcagtcctgagctcttcaccaagtacttctggcgcctctac
caccggctggaggagaccaaggatggcagctgtgtctccatgcccccctacttccgcttc
ctgacactcatggccttccatgtcttcctccaagagaaggtggacctggcagtggtggag
gtgggcattggcggggcttatgactgcaccaacatcatcaggaagcctgtggtgtgcgga
gtctcttctcttggcatcgaccacaccagcctcctgggggacacggtggagaaaatcgca
tggcagaaagggggcatctttaagcgaggtgtccctgccttcactgtgctccaacctgaa
ggtcccctggcagtgctgagggaccgagcccagcagatctcatgtcctctctacctgtgt
ccgacgctggaggccctggaggaaggggggccgccgctggccctgggcctggagggggag
caccagcggtccaacgccgccttggccttgcaactggcccactgctggctgcagcggcag
gaccgccatggtgccggggagctgaaggcatccaggccggggctcctgtggcagctgccc
ctggcacccgtgttccagcccacatcccacatgcggctcgggcttcggaacacggagtgg
ccgggccggacacaggtgctgcggcgtgggccccttacctggtacctggacggcgcgcac
acccccagcagcgtgcaggcctgcgtgcgctggttccgccaggcgctaaagggccgagag
aggccgagcggcagtgggcccgaggttcgagtcttgctcttcaatgctaccggggaccgg
gacccggtggccttgctgaaactgttgcagccgtgccagtttgactatgccgtcttctgc
cccaacctgacagaggtgtcatccacaggcaatgcagaccaacagaacttcacggtgaca
ctggaccaggttctgctgcgctgcctggaacaccagcagcactggaaccacctggacgaa
gagcaggccagcccggacctctggagcgcccccagtccagagcctggtgggcccacatcc
ctgctgctggcgccccacccaccccacacctgcagcgccagctccctcgtcttcagctgc
atttcacatgccttgcaatggatcagccaaggccgagaccctgtcttccagccacccact
cccctaaagggcctcctcacccaccctgtggctcacagtggggccagcgtactccatgag
gctgctgccatccatgtgctggtcactggcagcctgcacttggtgggtggtgtcctgaag
ctgctggagcctgcactgtcccagtag
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