KEGG   Piliocolobus tephrosceles (Ugandan red Colobus): 111551230
Entry
111551230         CDS       T07491                                 
Symbol
TBK1
Name
(RefSeq) serine/threonine-protein kinase TBK1
  KO
K05410  TANK-binding kinase 1 [EC:2.7.11.10]
Organism
pteh  Piliocolobus tephrosceles (Ugandan red Colobus)
Pathway
pteh04014  Ras signaling pathway
pteh04137  Mitophagy - animal
pteh04140  Autophagy - animal
pteh04620  Toll-like receptor signaling pathway
pteh04621  NOD-like receptor signaling pathway
pteh04622  RIG-I-like receptor signaling pathway
pteh04623  Cytosolic DNA-sensing pathway
pteh04657  IL-17 signaling pathway
pteh04936  Alcoholic liver disease
pteh05014  Amyotrophic lateral sclerosis
pteh05022  Pathways of neurodegeneration - multiple diseases
pteh05135  Yersinia infection
pteh05160  Hepatitis C
pteh05161  Hepatitis B
pteh05162  Measles
pteh05163  Human cytomegalovirus infection
pteh05164  Influenza A
pteh05165  Human papillomavirus infection
pteh05167  Kaposi sarcoma-associated herpesvirus infection
pteh05168  Herpes simplex virus 1 infection
pteh05169  Epstein-Barr virus infection
pteh05170  Human immunodeficiency virus 1 infection
pteh05171  Coronavirus disease - COVID-19
pteh05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:pteh00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04014 Ras signaling pathway
    111551230 (TBK1)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    111551230 (TBK1)
   04137 Mitophagy - animal
    111551230 (TBK1)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    111551230 (TBK1)
   04621 NOD-like receptor signaling pathway
    111551230 (TBK1)
   04622 RIG-I-like receptor signaling pathway
    111551230 (TBK1)
   04623 Cytosolic DNA-sensing pathway
    111551230 (TBK1)
   04657 IL-17 signaling pathway
    111551230 (TBK1)
 09160 Human Diseases
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    111551230 (TBK1)
   05161 Hepatitis B
    111551230 (TBK1)
   05160 Hepatitis C
    111551230 (TBK1)
   05171 Coronavirus disease - COVID-19
    111551230 (TBK1)
   05164 Influenza A
    111551230 (TBK1)
   05162 Measles
    111551230 (TBK1)
   05168 Herpes simplex virus 1 infection
    111551230 (TBK1)
   05163 Human cytomegalovirus infection
    111551230 (TBK1)
   05167 Kaposi sarcoma-associated herpesvirus infection
    111551230 (TBK1)
   05169 Epstein-Barr virus infection
    111551230 (TBK1)
   05165 Human papillomavirus infection
    111551230 (TBK1)
  09171 Infectious disease: bacterial
   05135 Yersinia infection
    111551230 (TBK1)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    111551230 (TBK1)
   05022 Pathways of neurodegeneration - multiple diseases
    111551230 (TBK1)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    111551230 (TBK1)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    111551230 (TBK1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:pteh01001]
    111551230 (TBK1)
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:pteh04131]
    111551230 (TBK1)
Enzymes [BR:pteh01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.10  IkappaB kinase
     111551230 (TBK1)
Protein kinases [BR:pteh01001]
 Serine/threonine kinases: Other
  IKK family [OT]
   111551230 (TBK1)
Membrane trafficking [BR:pteh04131]
 Autophagy
  Xenophagy
   Other xenophagy associated proteins
    111551230 (TBK1)
SSDB
Motif
Pfam: TBK1_CCD1 Pkinase TBK1_ULD PK_Tyr_Ser-Thr Pkinase_fungal ABC1 DUF713 Kinase-like CEP63 ubiquitin COG6_N
Other DBs
NCBI-GeneID: 111551230
NCBI-ProteinID: XP_023080857
Ensembl: ENSPTEG00000024803
UniProt: A0A8C9LRY0
LinkDB
Position
10:61529717..61578725
AA seq 729 aa
MQSTSNHLWLLSDILGQGATANVFRGRHKKTGDLFAIKVFNNISFLRPVDVQMREFEVLK
KLNHKNIVKLFAIEEETTTRHKVLIMEFCPCGSLYTVLEEPSNAYGLPESEFLIVLRDVV
GGMNHLRENGIVHRDIKPGNIMRVIGEDGQSVYKLTDFGAARELEDDEQFVSLYGTEEYL
HPDMYERAVLRKDHQKKYGATVDLWSIGVTFYHAATGSLPFRPFEGPRRNKEVMYKIITG
KPSGAISGVQKAENGPIDWSGDMPVSCSLSRGLQVLLTPVLANILEADQEKCWGFDQFFA
ETSDILHRMIIHVFSLQQMTAHKIYVHSYNTATIFHELVYKQTKIISSNQELIYEGRRLV
LEPGRLAQHFPKTTEENPIFVVSREPLNTIGLIYEKISLPKVHPRYDLDGDASMAKAITG
VVCYACRIASTLLLYQELMRKGIRWLIELIKDDYNETVHKKSEVVITLDFCIRNIEKTVK
VYEKLMKINLEAAELGEISDIHTKLLRLSSSQGTIETSLQDIDSRLSPGGSLADAWAHQE
GTHPKDRNVEKLQVLLNCMTEIYYQFKKDKAERRLAYNEEQIHKFDKQKLYYHATKAMTH
FTDECVKKYEAFLSKSEEWMRKMLHLRKQLLSLTNQCFDIEEEVSKYQDYTNELQETLPQ
KMFAASSGIKHTMTPIYPSSNTLVEMTLGMKKLKEEMEGVVKELAENNHILERFGSLTMD
GGLRNVDCL
NT seq 2190 nt   +upstreamnt  +downstreamnt
atgcagagcacttctaatcatctgtggcttttatctgatattttaggccaaggagctact
gcaaatgtctttcgtggaagacataagaaaactggtgatttatttgctatcaaagtattt
aataacataagcttccttcgtccagtggatgttcaaatgagagaatttgaagtgttgaaa
aaactcaatcacaaaaatattgtcaaattatttgctattgaagaggagacaacaacaaga
cataaagtacttattatggaattttgcccatgtgggagtttatacactgttttagaagag
ccttctaatgcctatggactaccagaatctgaattcttaattgttttgcgagatgtggtg
ggtggaatgaatcatcttcgagagaatggcatagtgcaccgtgatatcaagccaggaaat
atcatgcgtgttataggggaagatggacagtctgtgtacaaactcacagattttggtgca
gctagagaattagaagatgatgagcagtttgtttctctgtatggcacagaagaatatttg
caccctgatatgtatgagagagcagtgctaagaaaagatcatcagaagaaatatggagca
acagttgatctttggagcattggggtaacattttaccatgcagctactggatcactgcca
tttagaccctttgaagggcctcgtaggaataaagaagtgatgtataaaataattacagga
aagccttctggtgcaatatctggagtacaaaaggcagaaaatggaccaattgactggagt
ggagacatgcctgtttcttgcagtctttctcggggtcttcaggttctacttacccctgtt
cttgcaaacatccttgaagcagatcaggaaaagtgttggggttttgaccagttttttgca
gaaactagtgatatacttcaccgaatgataattcatgttttttcgctacaacaaatgaca
gctcataagatttatgttcatagctataatactgctactatatttcatgaactggtatat
aaacaaaccaaaattatttcttcaaatcaagaacttatctatgaagggcgacgcttagtc
ttagaacctggaagactggcacagcatttccctaaaactactgaggaaaaccccatattt
gtagtaagccgggaacctctgaataccataggattaatatatgaaaaaatttccctccct
aaagtacatccacgttatgatttagatggggatgctagcatggctaaggcaataacaggg
gttgtgtgttatgcctgcagaattgccagtaccttactgctttatcaggaattaatgcga
aaggggatacgatggctgattgaattaattaaagatgattacaatgaaactgttcacaaa
aagtcagaagttgtgatcacattggatttctgtatcagaaacattgaaaaaactgtgaaa
gtatatgaaaagttaatgaagatcaaccttgaagcggcagagttaggtgaaatttcagac
atacacaccaaattgttgagactttccagttctcagggaacaatagaaaccagtcttcag
gatattgacagcagattatctccaggtggatcgctggcagatgcatgggcacatcaagaa
ggcactcatccaaaagatagaaatgtggaaaaactacaagtcctgttaaattgcatgaca
gagatttactatcagttcaaaaaagacaaagcagaacgtagactagcttataatgaagaa
caaatccacaaatttgataagcaaaaactgtattaccatgcaaccaaagctatgacgcac
tttacagatgaatgtgttaaaaagtacgaggcatttttgagtaagtcagaagaatggatg
agaaagatgcttcatcttaggaaacagttattatctctgactaatcagtgttttgatatt
gaagaagaagtatcaaaatatcaagactatactaatgagttacaagaaactctgcctcag
aaaatgtttgctgcttccagtggaatcaaacataccatgaccccaatttatccaagttct
aacacattagtagaaatgactcttggtatgaagaaattaaaggaagagatggaaggggtg
gttaaagaacttgctgaaaataaccacattttagaaaggtttggctctttaaccatggat
ggtggccttcgcaacgttgactgtctttag

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