KEGG   Piliocolobus tephrosceles (Ugandan red Colobus): 111552066
Entry
111552066         CDS       T07491                                 
Symbol
PDE3A
Name
(RefSeq) cGMP-inhibited 3',5'-cyclic phosphodiesterase A
  KO
K19021  cGMP-inhibited 3',5'-cyclic phosphodiesterase A [EC:3.1.4.17]
Organism
pteh  Piliocolobus tephrosceles (Ugandan red Colobus)
Pathway
pteh00230  Purine metabolism
pteh01100  Metabolic pathways
pteh04022  cGMP-PKG signaling pathway
pteh04024  cAMP signaling pathway
pteh04924  Renin secretion
pteh05032  Morphine addiction
Brite
KEGG Orthology (KO) [BR:pteh00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    111552066 (PDE3A)
 09130 Environmental Information Processing
  09132 Signal transduction
   04024 cAMP signaling pathway
    111552066 (PDE3A)
   04022 cGMP-PKG signaling pathway
    111552066 (PDE3A)
 09150 Organismal Systems
  09152 Endocrine system
   04924 Renin secretion
    111552066 (PDE3A)
 09160 Human Diseases
  09165 Substance dependence
   05032 Morphine addiction
    111552066 (PDE3A)
Enzymes [BR:pteh01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.17  3',5'-cyclic-nucleotide phosphodiesterase
     111552066 (PDE3A)
SSDB
Motif
Pfam: PDEase_I
Other DBs
NCBI-GeneID: 111552066
NCBI-ProteinID: XP_023081925
Ensembl: ENSPTEG00000021193
UniProt: A0A8C9HJA4
LinkDB
Position
10:20517438..20836465
AA seq 1141 aa
MAVPVDAARVRDQPVHSGVSQAPTAGRDCHHRAELASPRDSGCRGCLGDLVLQPLRRSRK
LSSALCAGSLSFLLALLVRLVRGEVGCGLEQCKEAAAEEEEEAAPGAEGGVFPGPRGGAP
GGGARLSPWLQPSALLFSLLCAFFWMGLYLLRAGVRLPLAVALLAACCGGEALVQIGLGV
GEDHLLSLPAAGVVLSCLAAATWLVLRLRLGVLMIALTSAVRTVSLISLERFKVAWRPYL
AYLAGVLGILLARYVEQILPQSAEAAPREHLGSQLIAGTKEEIPVFKKRRRSSSVVSAEM
SGCSSKSHRRTSLPCIPREQLMGHSEWDHKRGSRGSQSSGTSITVDIAVMGEAHGLITDL
LADPSLPPNVCTSLRAVSNLLSTQLTFQAIHKPRVNPVTSLSENYTCSDSEESSEKDKLA
IPKRLRRSLPPGLLRRVSSTWTTTTSATGLPTLEPAPVRRDRSTSIKLQEAPSSSPDSWN
NPVMMTLTKSRSFTSSYAISAANHVKAKKQSRPGALAKISPLSSPCSSPLQGTPASSLVS
KISAVQFPESADTTVKQSLGSHRALTYTQSAPDLSPQILTPPVICSSCGRPYSQGNPADE
PLERSGVANRTPSRTDDTAQVTSDYETNNNSDSSDIVQNEDETECLREPLRKASACSTYA
PETMMFLDKPILAPEPLVMDNLDSIMEQLNTWNFPIFDLVENIGRKCGRILSQVSYRLFE
DMGLFEAFKIPIREFMNYFHALEIGYRDIPYHNRIHATDVLHAVWYLTTQPIPGLSTVIS
DHGSTSDSDSDSGFTHGHMGYVFSKTYNVTDDKYGCLSGNIPALELMALYVAAAMHDYDH
PGRTNAFLVATSAPQAVLYNDRSVLENHHAAAAWNLFMSRPEYNFLVNLDHVEFKHFRFL
VIEAILATDLKKHFDFVAKFNGKVNDDVGIDWTNENDRLLVCQMCIKLADINGPAKCKEL
HLQWTDGIVNEFYEQGDEEASLGLPISPFMDRSAPQLANLQESFISHIVGPLCNSYDSAG
LMPGKWVEDSDESGDTDDPEEEEEEAAAPNEEETCENNESPKKKTFKRRKIYCQITQHLL
QNHKMWKKVIEEEQRLAGVENQPLDPTPQSHSSEQIQAIKEEEEEKGKPRGEEIPTPKPD
Q
NT seq 3426 nt   +upstreamnt  +downstreamnt
atggcagtgcccgtcgacgctgcacgagtcagggaccagcccgtccacagtggggtgagt
caagcccccacggcgggccgggactgccaccatcgtgcagagctcgcatcgccgcgggac
tcaggctgccgtggctgcttgggagacctagtgctgcagccgctccggcgctctcggaaa
ctttcctccgcgctgtgcgcgggttccctgtcctttctgctggcgctgctggtgaggctg
gtccgcggggaggtcggctgtggcctggagcagtgtaaggaggcggcggcggaggaggag
gaggaagcagccccgggagcagaagggggcgtcttcccggggcctcggggaggtgctccc
gggggcggcgcgcggctcagcccctggctgcagccctcagcgctgctcttcagtctcctg
tgtgccttcttctggatgggcttgtacctcctgcgcgccggggtgcgcctgcctctggct
gtcgcgctgctggccgcctgctgtgggggggaagcgctcgtccagattgggctgggcgtc
ggggaggatcacttactctcgctcccagccgcgggggtggtgctcagctgcttggccgcg
gcgacatggctggtgctgaggctgaggctgggcgtcctcatgatcgccttgactagcgcg
gtcaggaccgtgtccctcatttccttagagaggttcaaggtcgcctggagaccttacctg
gcgtacttggccggcgtgctggggatcctcttggccaggtacgtggaacaaatcttgccg
cagtccgcggaggcggctccaagggagcatttggggtcccagctcattgctgggaccaag
gaagagatcccggtgtttaagaagaggaggcggtccagctctgtcgtgtccgccgagatg
tccggctgcagcagcaagtcccatcggaggacctccctgccctgtataccgagggaacag
ctcatggggcattcagaatgggaccacaaacgagggtcaagaggatctcagtcttcagga
accagtattactgtggacatcgccgtcatgggcgaggcccacggcctcattaccgacctc
ctggcagacccttctcttccaccaaacgtgtgcacatccttgagagccgtgagcaacttg
ctcagcacacagctcaccttccaggccattcacaagcccagagtgaatcccgtcacttcg
ctcagtgaaaactatacctgttctgactctgaagagagctctgaaaaagacaagcttgct
attccaaagcgcctgagaaggagtttgccccctggcttgttgagacgagtttcttccact
tggaccaccaccacctcggccacaggtctacctaccttggagcctgcaccagtacggaga
gaccgcagcaccagcatcaaactgcaggaagcaccttcatccagtcctgattcttggaat
aatccagtgatgatgaccctcaccaaaagcagatcctttacttcatcctatgctatttct
gcagctaaccatgtaaaggctaaaaagcaaagtcgaccaggtgccctcgctaaaatttca
cctctttcatcgccctgctcctcacctctccaagggactcctgccagcagcctggtcagc
aaaatttctgcagtgcagtttccagaatctgctgacacaactgtcaaacaaagtctaggt
tctcacagggccttaacttacactcagagtgcccctgacctatcccctcaaatcctgact
ccacctgttatatgtagcagctgtggcagaccatattcccaagggaatcctgctgatgag
cccctggagagaagtggggtagccaatcggacaccaagtagaacagatgacactgctcaa
gttacctctgattatgaaaccaataacaacagtgacagcagtgacattgtacagaatgaa
gatgaaacagagtgcctgagagagcctctgaggaaagcatcggcttgcagcacctatgct
cctgagaccatgatgtttctggacaaaccaattcttgctcctgaacctcttgtcatggat
aacctggactcaattatggagcagctaaatacttggaattttccgattttcgatttagtg
gaaaatataggaagaaaatgtggccgtattcttagtcaggtatcttacagactttttgaa
gacatgggcctctttgaagcttttaaaattccaattagggaatttatgaattattttcat
gctttggagattggatacagggatattccttatcataacagaatccatgccactgatgtt
ttacatgctgtttggtatcttactacacagcctattccaggcctctcaactgtgattagt
gatcatggttcaaccagtgattcagattctgacagtggatttacacatggacatatggga
tatgtattctcaaaaacgtataatgtgacagatgataaatacggatgtctgtctgggaat
atacctgccttagagttgatggcgctgtatgtggctgcagccatgcacgattatgatcac
ccaggaaggactaatgctttcctggttgcaactagtgctcctcaggcggtgctatataac
gatcgttcagttttggagaatcatcacgcagctgctgcatggaatcttttcatgtcccgg
ccagagtataacttcttagttaaccttgaccatgtggaatttaagcatttccgtttcctt
gtcattgaagcaattttggccactgacctgaagaaacactttgacttcgtagccaaattt
aatggcaaggtaaatgatgatgttggaatagattggaccaatgaaaatgatcgtctactg
gtttgtcaaatgtgtataaagttggctgatatcaatggtccagctaaatgtaaagaactc
catcttcagtggacagatggtattgtcaatgaattttacgaacagggtgatgaagaggcc
agccttgggttacccataagccccttcatggatcgttctgctcctcagctggccaacctt
caggaatccttcatctctcacattgtggggcctctgtgcaactcctatgattcagccgga
ctaatgccaggaaaatgggtggaagacagcgatgagtcaggagatactgatgacccagaa
gaagaggaggaagaagcagcagcaccaaatgaagaggaaacctgtgaaaataatgaatct
ccaaaaaagaagactttcaaaaggagaaaaatctactgccaaataactcagcacctctta
cagaaccacaagatgtggaagaaagtcattgaagaggagcaacggttggcaggtgtagaa
aatcagcccctggacccgacccctcaatcgcactcttcagaacagatccaggctatcaag
gaagaagaagaagagaaagggaaaccaagaggggaggagataccaaccccaaagccagac
cagtga

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