KEGG   Piliocolobus tephrosceles (Ugandan red Colobus): 111554538
Entry
111554538         CDS       T07491                                 
Symbol
MAPK8
Name
(RefSeq) mitogen-activated protein kinase 8 isoform X1
  KO
K04440  mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
Organism
pteh  Piliocolobus tephrosceles (Ugandan red Colobus)
Pathway
pteh01522  Endocrine resistance
pteh04010  MAPK signaling pathway
pteh04012  ErbB signaling pathway
pteh04014  Ras signaling pathway
pteh04024  cAMP signaling pathway
pteh04068  FoxO signaling pathway
pteh04071  Sphingolipid signaling pathway
pteh04137  Mitophagy - animal
pteh04140  Autophagy - animal
pteh04141  Protein processing in endoplasmic reticulum
pteh04210  Apoptosis
pteh04215  Apoptosis - multiple species
pteh04217  Necroptosis
pteh04310  Wnt signaling pathway
pteh04380  Osteoclast differentiation
pteh04510  Focal adhesion
pteh04530  Tight junction
pteh04620  Toll-like receptor signaling pathway
pteh04621  NOD-like receptor signaling pathway
pteh04622  RIG-I-like receptor signaling pathway
pteh04625  C-type lectin receptor signaling pathway
pteh04657  IL-17 signaling pathway
pteh04658  Th1 and Th2 cell differentiation
pteh04659  Th17 cell differentiation
pteh04660  T cell receptor signaling pathway
pteh04664  Fc epsilon RI signaling pathway
pteh04668  TNF signaling pathway
pteh04722  Neurotrophin signaling pathway
pteh04723  Retrograde endocannabinoid signaling
pteh04728  Dopaminergic synapse
pteh04750  Inflammatory mediator regulation of TRP channels
pteh04910  Insulin signaling pathway
pteh04912  GnRH signaling pathway
pteh04914  Progesterone-mediated oocyte maturation
pteh04917  Prolactin signaling pathway
pteh04920  Adipocytokine signaling pathway
pteh04926  Relaxin signaling pathway
pteh04930  Type II diabetes mellitus
pteh04931  Insulin resistance
pteh04932  Non-alcoholic fatty liver disease
pteh04933  AGE-RAGE signaling pathway in diabetic complications
pteh04935  Growth hormone synthesis, secretion and action
pteh04936  Alcoholic liver disease
pteh05010  Alzheimer disease
pteh05012  Parkinson disease
pteh05016  Huntington disease
pteh05017  Spinocerebellar ataxia
pteh05020  Prion disease
pteh05022  Pathways of neurodegeneration - multiple diseases
pteh05132  Salmonella infection
pteh05133  Pertussis
pteh05135  Yersinia infection
pteh05142  Chagas disease
pteh05145  Toxoplasmosis
pteh05152  Tuberculosis
pteh05161  Hepatitis B
pteh05162  Measles
pteh05166  Human T-cell leukemia virus 1 infection
pteh05167  Kaposi sarcoma-associated herpesvirus infection
pteh05169  Epstein-Barr virus infection
pteh05170  Human immunodeficiency virus 1 infection
pteh05171  Coronavirus disease - COVID-19
pteh05200  Pathways in cancer
pteh05208  Chemical carcinogenesis - reactive oxygen species
pteh05210  Colorectal cancer
pteh05212  Pancreatic cancer
pteh05231  Choline metabolism in cancer
pteh05415  Diabetic cardiomyopathy
pteh05417  Lipid and atherosclerosis
pteh05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:pteh00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04141 Protein processing in endoplasmic reticulum
    111554538 (MAPK8)
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    111554538 (MAPK8)
   04012 ErbB signaling pathway
    111554538 (MAPK8)
   04014 Ras signaling pathway
    111554538 (MAPK8)
   04310 Wnt signaling pathway
    111554538 (MAPK8)
   04668 TNF signaling pathway
    111554538 (MAPK8)
   04068 FoxO signaling pathway
    111554538 (MAPK8)
   04071 Sphingolipid signaling pathway
    111554538 (MAPK8)
   04024 cAMP signaling pathway
    111554538 (MAPK8)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    111554538 (MAPK8)
   04137 Mitophagy - animal
    111554538 (MAPK8)
  09143 Cell growth and death
   04210 Apoptosis
    111554538 (MAPK8)
   04215 Apoptosis - multiple species
    111554538 (MAPK8)
   04217 Necroptosis
    111554538 (MAPK8)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    111554538 (MAPK8)
   04530 Tight junction
    111554538 (MAPK8)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    111554538 (MAPK8)
   04621 NOD-like receptor signaling pathway
    111554538 (MAPK8)
   04622 RIG-I-like receptor signaling pathway
    111554538 (MAPK8)
   04625 C-type lectin receptor signaling pathway
    111554538 (MAPK8)
   04660 T cell receptor signaling pathway
    111554538 (MAPK8)
   04658 Th1 and Th2 cell differentiation
    111554538 (MAPK8)
   04659 Th17 cell differentiation
    111554538 (MAPK8)
   04657 IL-17 signaling pathway
    111554538 (MAPK8)
   04664 Fc epsilon RI signaling pathway
    111554538 (MAPK8)
  09152 Endocrine system
   04910 Insulin signaling pathway
    111554538 (MAPK8)
   04920 Adipocytokine signaling pathway
    111554538 (MAPK8)
   04912 GnRH signaling pathway
    111554538 (MAPK8)
   04914 Progesterone-mediated oocyte maturation
    111554538 (MAPK8)
   04917 Prolactin signaling pathway
    111554538 (MAPK8)
   04926 Relaxin signaling pathway
    111554538 (MAPK8)
   04935 Growth hormone synthesis, secretion and action
    111554538 (MAPK8)
  09156 Nervous system
   04728 Dopaminergic synapse
    111554538 (MAPK8)
   04723 Retrograde endocannabinoid signaling
    111554538 (MAPK8)
   04722 Neurotrophin signaling pathway
    111554538 (MAPK8)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    111554538 (MAPK8)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    111554538 (MAPK8)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    111554538 (MAPK8)
   05208 Chemical carcinogenesis - reactive oxygen species
    111554538 (MAPK8)
   05231 Choline metabolism in cancer
    111554538 (MAPK8)
  09162 Cancer: specific types
   05210 Colorectal cancer
    111554538 (MAPK8)
   05212 Pancreatic cancer
    111554538 (MAPK8)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    111554538 (MAPK8)
   05170 Human immunodeficiency virus 1 infection
    111554538 (MAPK8)
   05161 Hepatitis B
    111554538 (MAPK8)
   05171 Coronavirus disease - COVID-19
    111554538 (MAPK8)
   05162 Measles
    111554538 (MAPK8)
   05167 Kaposi sarcoma-associated herpesvirus infection
    111554538 (MAPK8)
   05169 Epstein-Barr virus infection
    111554538 (MAPK8)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    111554538 (MAPK8)
   05135 Yersinia infection
    111554538 (MAPK8)
   05133 Pertussis
    111554538 (MAPK8)
   05152 Tuberculosis
    111554538 (MAPK8)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    111554538 (MAPK8)
   05142 Chagas disease
    111554538 (MAPK8)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    111554538 (MAPK8)
   05012 Parkinson disease
    111554538 (MAPK8)
   05016 Huntington disease
    111554538 (MAPK8)
   05017 Spinocerebellar ataxia
    111554538 (MAPK8)
   05020 Prion disease
    111554538 (MAPK8)
   05022 Pathways of neurodegeneration - multiple diseases
    111554538 (MAPK8)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    111554538 (MAPK8)
   05418 Fluid shear stress and atherosclerosis
    111554538 (MAPK8)
   05415 Diabetic cardiomyopathy
    111554538 (MAPK8)
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    111554538 (MAPK8)
   04936 Alcoholic liver disease
    111554538 (MAPK8)
   04932 Non-alcoholic fatty liver disease
    111554538 (MAPK8)
   04931 Insulin resistance
    111554538 (MAPK8)
   04933 AGE-RAGE signaling pathway in diabetic complications
    111554538 (MAPK8)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    111554538 (MAPK8)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:pteh01001]
    111554538 (MAPK8)
Enzymes [BR:pteh01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.24  mitogen-activated protein kinase
     111554538 (MAPK8)
Protein kinases [BR:pteh01001]
 Serine/threonine kinases: CMGC group
  MAPK family [OT]
   111554538 (MAPK8)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Kdo ABC1 RIO1 Kinase-like FTA2 APH DUF530
Other DBs
NCBI-GeneID: 111554538
NCBI-ProteinID: XP_023085904
Ensembl: ENSPTEG00000022165
LinkDB
Position
9:84623465..84758747
AA seq 427 aa
MSRSKRDNNFYSVEIGDSTFTVLKRYQNLKPIGSGAQGIVCAAYDAILERNVAIKKLSRP
FQNQTHAKRAYRELVLMKCVNHKNIIGLLNVFTPQKSLEEFQDVYIVMELMDANLCQVIQ
MELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSF
MMTPYVVTRYYRAPEVILGMGYKENVDIWSVGCIMGEMIKGGVLFPGTDHIDQWNKVIEQ
LGTPCPEFMKKLQPTVRTYVENRPKYAGYSFEKLFPDVLFPADSEHNKLKASQARDLLSK
MLVIDASKRISVDEALQHPYINVWYDPSEAEAPPPKIPDKQLDEREHTIEEWKELIYKEV
MDLEERTKNGVIRGQPSPLGAAVINGSQHPSSSSSVNDVSSMSTDPTLASDTDSSLEASA
GPLGCCR
NT seq 1284 nt   +upstreamnt  +downstreamnt
atgagcagaagcaagcgtgacaacaatttttatagtgtagaaattggagattctacattc
acagtcctgaaacggtatcagaatttaaaacctataggctcaggagcgcaaggaatagta
tgtgcagcttatgatgccattcttgaaagaaatgttgcaatcaagaagctaagccgacca
tttcagaatcagactcatgccaagcgggcctacagagagctagttcttatgaaatgtgtt
aatcacaaaaatataattggccttttgaatgttttcacaccacagaaatccctagaagaa
tttcaagatgtttacatagtcatggagctcatggatgccaatctttgccaagtgattcag
atggagctagatcatgaaagaatgtcctaccttctctatcagatgctgtgtggaatcaag
caccttcactctgctggaattattcatcgggacttaaagcccagtaatatagtagtaaaa
tctgactgcactttgaagattcttgactttggtctggccaggactgcaggaacgagtttt
atgatgacgccttatgtagtgactcgctactacagagcacccgaggtcatccttggcatg
ggctacaaggaaaacgttgacatttggtcagttgggtgcatcatgggagaaatgatcaaa
ggtggtgttttgttcccaggtacagatcatattgatcagtggaataaagttattgaacag
cttggaacaccatgtcctgaattcatgaagaaactgcaaccaacagtaaggacttatgtt
gaaaacagacctaaatatgctggatatagcttcgaaaaactcttccctgatgtacttttc
ccagctgactcggaacacaacaaacttaaagccagtcaggcaagggatttgttatccaaa
atgctggtaatagatgcatctaaaaggatctctgtagatgaagctctccaacacccgtac
atcaatgtctggtatgatccttctgaagcagaagctccaccaccaaagatccctgacaag
cagttagatgaaagggaacacacaatagaagagtggaaagaattgatatataaggaagtt
atggacttggaggagagaaccaagaatggagttatacgggggcagccctctcctttaggt
gcagcagtgatcaatggctctcagcatccatcgtcatcgtcgtctgtcaatgatgtgtct
tcaatgtcaacagatccgactttggcctcggatacagacagcagtctagaagcatcagct
gggcctctgggctgctgtagatga

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