Candidatus Profftia tarda: PROFFT_A_01710
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Entry
PROFFT_A_01710 CDS
T07286
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
ptf
Candidatus Profftia tarda
Pathway
ptf00300
Lysine biosynthesis
ptf00550
Peptidoglycan biosynthesis
ptf01100
Metabolic pathways
ptf01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
ptf00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
PROFFT_A_01710 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
PROFFT_A_01710 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
PROFFT_A_01710 (murF)
Enzymes [BR:
ptf01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
PROFFT_A_01710 (murF)
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Gene cluster
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
CAD6508540
UniProt:
A0A8E4EY16
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All DBs
Position
1:350202..351551
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AA seq
449 aa
AA seq
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MFPISLEIIAQVVHGKLIGTDIQVRDVVIDTRKITSNCMFIALKGKRFDAHDFAVDAIQK
GANTLLVSKYLPISVPQILVADTRIALCLLASWSRQQVSARIIALTGSSGKTLVKEITAS
ILQYCGNVLHTTGNFNNNIGVSLTLLLLKPEHKFAVLELGANHIGEISYTSNLVKPESVL
INNIAAAHLEGFGSLAGVAKAKGEIFDGLALNGTAIINADSNDWSNWKEKIAAQRVWRFS
LNEGKEVDFFATGVRVTQEVTEFKLHTPFGTISVALLLPGYHNIANVLAASALAISVGAT
LENIQKGLNELKAIPGRLFPISLNKQQLILDDTYNANVGSMIAAAHVLSSKPGYRVMVVG
YMEELGTEEAEYHRQVGIAFREVGVNKVLSVGGLSYIISEASGCGEHFTDKKSLVQRLKN
ILSEHSTITVLVKGSRGSAMEQVVHALSV
NT seq
1350 nt
NT seq
+upstream
nt +downstream
nt
atgttccctatttccttagaaattatagcgcaagttgtacatggaaaattgattggaacg
gatattcaggttagagatgtcgtaatagatacacgaaaaattacaagtaattgtatgttt
attgccttaaaaggaaaaagatttgatgctcacgattttgctgttgatgctatacaaaaa
ggtgcgaatactttattggtaagtaaatatttacccatttctgtgccgcaaattctagtg
gccgatactagaattgctttatgtttacttgcgtcatggtcacgtcagcaagtttcagca
cgtattattgctctgacaggatcttcaggtaaaactttggttaaagaaattaccgcttca
atcctacaatattgcggtaatgtgctgcatactacaggtaattttaataataatatcgga
gtatctttaacgctattactgcttaagccagaacataaatttgctgtgctggaacttggt
gctaaccatataggagaaatttcttatacaagcaatctagtgaaacctgaaagtgtgctg
ataaataatatagcagctgctcatctggagggttttggttctttggcaggagttgctaag
gctaaaggagaaatatttgatggcttggcattaaacggaacagccattataaacgctgat
agtaatgactggtcaaactggaaagaaaaaattgccgctcagcgcgtatggcgtttctca
ttaaatgaaggtaaagaggttgatttctttgcaactggagttcgagtaacgcaggaagtt
accgaatttaaactacatactccattcggaacaatttcagtagccctactattaccaggc
tatcataatatagcaaacgttttagctgctagtgctctagctatatctgttggtgcaact
ctagaaaatatacagaagggacttaatgagttaaaagctattcccggtcgtttgttcccg
attagtttaaataaacaacaattaatactagatgatacctacaatgctaacgtaggatct
atgattgctgctgctcacgttttgagctctaagccaggttatcgagttatggtagttgga
tatatggaggaattagggactgaggaagcagaatatcaccgtcaggtgggcattgctttc
cgagaagttggagttaataaagttctgagtgttggtggattaagctatattattagtgag
gctagtggttgtggtgaacattttacagataaaaaatctttggttcaaagactaaaaaac
atattatctgaacattcaacaatcactgtgctagtgaagggttcaagaggttctgctatg
gagcaggtagtgcatgctttatctgtgtag
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