KEGG   Panthera tigris altaica (Amur tiger): 102948685
Entry
102948685         CDS       T02988                                 
Symbol
PTGS2
Name
(RefSeq) prostaglandin-endoperoxide synthase 2
  KO
K11987  prostaglandin-endoperoxide synthase 2 [EC:1.14.99.1]
Organism
ptg  Panthera tigris altaica (Amur tiger)
Pathway
ptg00590  Arachidonic acid metabolism
ptg01100  Metabolic pathways
ptg04064  NF-kappa B signaling pathway
ptg04148  Efferocytosis
ptg04370  VEGF signaling pathway
ptg04625  C-type lectin receptor signaling pathway
ptg04657  IL-17 signaling pathway
ptg04668  TNF signaling pathway
ptg04723  Retrograde endocannabinoid signaling
ptg04726  Serotonergic synapse
ptg04913  Ovarian steroidogenesis
ptg04921  Oxytocin signaling pathway
ptg04923  Regulation of lipolysis in adipocytes
ptg05010  Alzheimer disease
ptg05022  Pathways of neurodegeneration - multiple diseases
ptg05140  Leishmaniasis
ptg05163  Human cytomegalovirus infection
ptg05165  Human papillomavirus infection
ptg05167  Kaposi sarcoma-associated herpesvirus infection
ptg05200  Pathways in cancer
ptg05204  Chemical carcinogenesis - DNA adducts
ptg05206  MicroRNAs in cancer
ptg05222  Small cell lung cancer
Brite
KEGG Orthology (KO) [BR:ptg00001]
 09100 Metabolism
  09103 Lipid metabolism
   00590 Arachidonic acid metabolism
    102948685 (PTGS2)
 09130 Environmental Information Processing
  09132 Signal transduction
   04370 VEGF signaling pathway
    102948685 (PTGS2)
   04064 NF-kappa B signaling pathway
    102948685 (PTGS2)
   04668 TNF signaling pathway
    102948685 (PTGS2)
 09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    102948685 (PTGS2)
 09150 Organismal Systems
  09151 Immune system
   04625 C-type lectin receptor signaling pathway
    102948685 (PTGS2)
   04657 IL-17 signaling pathway
    102948685 (PTGS2)
  09152 Endocrine system
   04923 Regulation of lipolysis in adipocytes
    102948685 (PTGS2)
   04913 Ovarian steroidogenesis
    102948685 (PTGS2)
   04921 Oxytocin signaling pathway
    102948685 (PTGS2)
  09156 Nervous system
   04726 Serotonergic synapse
    102948685 (PTGS2)
   04723 Retrograde endocannabinoid signaling
    102948685 (PTGS2)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    102948685 (PTGS2)
   05206 MicroRNAs in cancer
    102948685 (PTGS2)
   05204 Chemical carcinogenesis - DNA adducts
    102948685 (PTGS2)
  09162 Cancer: specific types
   05222 Small cell lung cancer
    102948685 (PTGS2)
  09172 Infectious disease: viral
   05163 Human cytomegalovirus infection
    102948685 (PTGS2)
   05167 Kaposi sarcoma-associated herpesvirus infection
    102948685 (PTGS2)
   05165 Human papillomavirus infection
    102948685 (PTGS2)
  09174 Infectious disease: parasitic
   05140 Leishmaniasis
    102948685 (PTGS2)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    102948685 (PTGS2)
   05022 Pathways of neurodegeneration - multiple diseases
    102948685 (PTGS2)
Enzymes [BR:ptg01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.99  Miscellaneous
    1.14.99.1  prostaglandin-endoperoxide synthase
     102948685 (PTGS2)
SSDB
Motif
Pfam: An_peroxidase EGF
Other DBs
NCBI-GeneID: 102948685
NCBI-ProteinID: XP_007096301
UniProt: A0A8C9MBK8
LinkDB
Position
Un
AA seq 604 aa
MLARALLLCAALALCRAANPCCSNPCQNQGVCLSIGFDQYKCDCTRTGFYGENCSTPEFL
TRIKLFLKPTPNTVHYILTHFKGVWNIVNNIPFLQNIIMKYVLTSRSHLIESPPTYNVDY
GYKSWEAFSNLSYYTRALPPVADDCPTPMGVKGKKELPDSKEIVEKFLLRRKFIPDPQGT
NMMFAFFAQHFTHQFFKTDHKRGPAFTKGLGHGVDLSHVYGETLDRQHKLRLFKDGKMKY
QIIDGEVYPPTVKDTQVEMIYPPHVPEHLRFAVGQEVFGLVPGLMMYATIWLREHNRVCD
VLKQEHPEWDDERLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQ
NRIAAEFNTLYHWHPLLPDTLQIDDQEYNFQQFVYNNSILLEHGLTQFVESFSRQIAGRV
AGGRNVPAAVQQVAKASIDQSRQMKYQSLNEYRKRFRLKPYTSFEELTGEKEMAAGLEAL
YGDIDAMELYPALLVEKPRPDAIFGETMVEMGAPFSLKGLMGNPICSPDYWKPSTFGGEV
GFKIINTASIQSLICNNVKGCPFTAFSVQDPQLTKTVTINASSSHSGLDDINPTVLLKER
STEL
NT seq 1815 nt   +upstreamnt  +downstreamnt
atgcttgcccgcgccctgctgctctgcgccgccctggcgctctgccgtgcagcaaatcct
tgctgttccaacccatgccaaaaccaaggtgtatgtctgagcataggatttgaccagtat
aagtgtgactgtacccgaacaggattctatggtgaaaactgttcaacacctgaatttctg
acaagaataaagttattcctgaaacccactccaaatacagtgcactacatacttacccac
ttcaagggagtctggaacattgtcaataacattcccttcctgcaaaatataattatgaaa
tatgtgttgacatccaggtcacatttgattgagagcccaccaacttacaatgtggactat
ggctataaaagctgggaagccttttccaatctctcctattataccagagctcttccccct
gtggctgatgactgcccaacacccatgggtgtgaaaggcaagaaagagcttcctgattca
aaagagattgtggaaaaatttcttctaagaagaaagttcattcctgacccccaaggcaca
aatatgatgtttgcattttttgcccaacacttcacccatcaatttttcaagacagatcat
aagcgaggaccagctttcaccaaaggactgggccatggggtggacttaagtcatgtttat
ggcgaaactttggatagacagcataaactgcgccttttcaaggatggaaaaatgaaatac
cagataatcgatggggaggtgtatcctcccacagtcaaagatactcaggtcgagatgatc
tacccacctcacgttcctgaacacctgcggtttgctgtgggccaggaggtctttggtctg
gtgcctggtctgatgatgtacgccacaatttggctgcgggaacacaacagagtgtgtgat
gtgcttaaacaggagcatccagaatgggatgatgagcggttgttccagacgagcaggcta
atactgataggagaaaccattaagattgtgattgaagactatgtacaacacttgagtggc
tatcacttcaaactgaagtttgacccagagctgcttttcaaccaacaattccaataccaa
aaccgtattgctgctgagtttaacacactctaccactggcatccccttctgcctgacacc
ttgcaaatagatgaccaggagtacaatttccagcagtttgtctacaacaactctatatta
ctggaacatgggcttacccagttcgtggaatcattcagcaggcaaattgctggcagggtt
gctggtggtaggaatgttccagctgcagtgcagcaagtagcaaaggcctcaatcgaccag
agcagacagatgaagtaccagtctcttaatgagtatcgcaaacgctttcggctgaagccc
tatacatcgtttgaagaactcacaggagagaaggaaatggctgcggggttagaagcactt
tatggtgatattgatgccatggagctgtatcctgcccttctggtagaaaagcctcgccct
gatgccatctttggtgagaccatggtagaaatgggagcaccattctccttgaaagggctt
atgggtaatcctatatgctctcctgactactggaagcctagcacttttggtggagaagta
ggttttaaaatcatcaacactgcctcgattcagtctctcatctgcaataacgtgaagggc
tgtccttttactgcattcagtgttcaagatccacagctcaccaaaacagtcaccattaat
gcaagctcttcgcactctggactggatgatatcaatcccacagtactgctaaaagaacgt
tcaactgaactgtag

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