Panthera tigris altaica (Amur tiger): 102949569
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Entry
102949569 CDS
T02988
Symbol
ABL1
Name
(RefSeq) ABL proto-oncogene 1, non-receptor tyrosine kinase
KO
K06619
abelson tyrosine-protein kinase 1 [EC:
2.7.10.2
]
Organism
ptg
Panthera tigris altaica (Amur tiger)
Pathway
ptg04012
ErbB signaling pathway
ptg04014
Ras signaling pathway
ptg04110
Cell cycle
ptg04360
Axon guidance
ptg04517
IgSF CAM signaling
ptg04722
Neurotrophin signaling pathway
ptg05200
Pathways in cancer
ptg05206
MicroRNAs in cancer
ptg05208
Chemical carcinogenesis - reactive oxygen species
ptg05220
Chronic myeloid leukemia
ptg05416
Viral myocarditis
Brite
KEGG Orthology (KO) [BR:
ptg00001
]
09130 Environmental Information Processing
09132 Signal transduction
04012 ErbB signaling pathway
102949569 (ABL1)
04014 Ras signaling pathway
102949569 (ABL1)
09133 Signaling molecules and interaction
04517 IgSF CAM signaling
102949569 (ABL1)
09140 Cellular Processes
09143 Cell growth and death
04110 Cell cycle
102949569 (ABL1)
09150 Organismal Systems
09156 Nervous system
04722 Neurotrophin signaling pathway
102949569 (ABL1)
09158 Development and regeneration
04360 Axon guidance
102949569 (ABL1)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
102949569 (ABL1)
05206 MicroRNAs in cancer
102949569 (ABL1)
05208 Chemical carcinogenesis - reactive oxygen species
102949569 (ABL1)
09162 Cancer: specific types
05220 Chronic myeloid leukemia
102949569 (ABL1)
09166 Cardiovascular disease
05416 Viral myocarditis
102949569 (ABL1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
ptg01001
]
102949569 (ABL1)
Enzymes [BR:
ptg01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
102949569 (ABL1)
Protein kinases [BR:
ptg01001
]
Non-receptor tyrosine kinases
ABL family
102949569 (ABL1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
SH2
SH3_1
SH3_2
SH3_9
SH3_6
Motif
Other DBs
NCBI-GeneID:
102949569
NCBI-ProteinID:
XP_007078897
LinkDB
All DBs
Position
Un
AA seq
1053 aa
AA seq
DB search
MGQQPGKVLGDQRRPSLPALHFIKGAGKKESSRHGGPHCNVFVEHEALQRPVASDFEPQG
LSEAARWNSKENLLAGPSENDPNLFVALYDFVASGDNTLSITKGEKLRVLGYNHNGEWCE
AQTKNGQGWVPSNYITPVNSLEKHSWYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQR
SISLRYEGRVYHYRINTASDGKLYVSSESRFNTLAELVHHHSTVADGLITTLHYPAPKRN
KPTVYGVSPNYDKWEMERTDITMKHKLGGGQYGEVYEGVWKKYSLTVAVKTLKEDTMEVE
EFLKEAAVMKEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLRECNRQEVNAVVLL
YMATQISSAMEYLEKKNFILRDLAARNCLVGENHLVKVADFGLSRLMTGDTYTAHAGAKF
PIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYELLEKDYRMERP
EGCPEKVYELMRACWQWNPSDRPSFAEIHQAFETMFQESSISDEVEKELGKKGVRGVAST
LLQAPELPTKTRTSRRAAEHKDPTDVPETPHSKGPGETDPLDHEPPVSPLLPRKERGPQD
GGLNEDERLLPKDKKTNLFSALIKKKKKTAPTPPKRSSSFREMDGQPERKGAGEEEGRET
SNGAPALPPSDAAEPAKSPKPSSGAGVPNGAFRESGGAGFRSPHLWKKSSTLTSSRLAAS
EEESGGSSSKRFLRSCSASCVPHGARDTEWRSVTLPRDLQSTGRQFDSSTFGGHKSEKPA
LPRKRASENRSDQAARGWVTPPPRLVKKTEEAADEVFRDAGESSPGSSPPSLTPKLLRRQ
VTGAPSSGLPHKDETAKSGALGTPVTAEPVPPASRAGPGASGGTGKAPAEEPRARRHKPS
SESPGRDKGKLSKLKPAPPPPPPASVGKAGKPAQNPTQEAAGEASTGGETKTAAGAQRGP
QPARRPPPPRCHQQPPPWPGTSPRLLPSSLSYRPACLFGKPASLRSGSPAAPSPRAWSWT
APRPCAWPSPRTPSRWPAIAPCWKPAKTCTRSA
NT seq
3162 nt
NT seq
+upstream
nt +downstream
nt
atggggcagcagcctggaaaagttcttggggaccagaggaggccaagcttgcctgccctg
cactttatcaaaggagcagggaagaaggaatcatcgaggcacgggggtccgcactgcaat
gtctttgtggaacacgaagcccttcagaggccagtagcgtctgactttgagccccaaggt
ctgagcgaagcagctcgttggaactccaaggaaaaccttcttgctggtcccagtgaaaat
gaccccaacctttttgttgcactgtatgattttgtggccagtggggataacaccctaagc
atcactaaaggtgaaaagctccgggttctgggctacaaccacaatggggaatggtgtgag
gcccagaccaaaaatggccaagggtgggtcccgagcaactacatcacgccggtcaacagt
ctggagaaacattcctggtaccacgggcccgtgtcccgcaacgccgccgagtacctgctg
agcagcgggatcaacggcagcttcttggtgcgggagagcgagagcagccccggccagagg
tccatctcgctgagatacgaagggagggtgtaccactacaggatcaacaccgcttccgat
ggcaagctctacgtctcctcagagagccgcttcaacactttggcggagttggttcatcat
cactcgactgtggcggacgggctcatcaccactctccattacccagcccccaagcgcaac
aagcccaccgtctacggcgtgtcccccaactacgacaagtgggagatggaacgcacggac
atcaccatgaagcacaagctgggaggcggccagtacggagaggtgtacgagggcgtgtgg
aagaaatacagcctgacggtggccgtgaagaccttgaaggaggacaccatggaggtggaa
gagttcttgaaagaagccgcagtgatgaaggagatcaagcaccccaacctcgtgcagttg
ctgggggtctgtacccgggagcccccgttctatataatcactgagttcatgacctatggg
aacctgctggattacctgcgggagtgtaaccggcaggaggtgaacgctgtggtgctgctg
tatatggccacgcagatctcgtcagccatggagtacctggagaagaagaacttcatcctc
agagatcttgctgcccgaaactgcctggtaggggagaaccacttggtgaaggtggctgat
ttcggcctgagcaggttaatgacaggggatacgtacacagcccacgccggggccaagttc
cccatcaagtggacagcgccagaaagcctggcctacaacaagttctccatcaagtccgac
gtctgggcatttggagtactgctttgggaaattgctacctacggtatgtcaccttaccca
ggaattgacctgtcccaggtatacgagctgctagagaaagactatcgcatggaacgcccg
gaaggctgcccagagaaggtctacgaactcatgcgagcatgttggcagtggaatccctcc
gaccggccctcctttgctgaaatccaccaagcctttgagaccatgttccaagagtccagc
atatcagatgaagtggaaaaggaactggggaaaaaaggtgtgcgaggggttgcgagtact
ttgctgcaggccccagagctgcccaccaagacgagaacgtccaggagagccgcggagcac
aaagaccccactgacgtgcccgagacgccccactccaagggcccaggagagaccgatcct
ctggaccacgagccccccgtgtctcccctgctccctcgaaaagaacgaggtccccaggat
ggcggcctgaatgaggatgagcgcctgcttcccaaagacaaaaagaccaacttgttcagt
gccttgatcaagaagaagaagaaaacggccccaacgcccccgaaacgcagcagctccttc
cgggagatggacggccagcccgagcgcaagggggccggcgaggaagagggccgagaaacc
agcaacggggcaccggctctcccaccctcggacgcagccgagccagccaagtccccaaag
cccagcagcggggctggcgtccccaacggagccttccgggagtccgggggtgcaggcttc
cggtctccccacctgtggaaaaagtccagtacgctgaccagcagccgcctagcagccagc
gaggaggagagtggcgggagctccagcaagcgcttcctgcggtcctgctcggcctcctgc
gtgccccacggagccagggacaccgagtggaggtccgtcacactgcctcgggacctgcag
tccacgggcaggcagttcgactcgtccacgtttggagggcacaaaagcgagaagccggct
ctgcctcggaagcgggcgagtgagaacaggtccgaccaggcggccagaggctgggtgact
cccccacccaggctggtgaaaaagaccgaggaagcagccgatgaggtctttcgagacgcg
ggggagtccagcccaggctccagccccccaagtctgactccaaaactcctccgcaggcag
gtcacgggggctccttcctctggccttccccacaaggacgagaccgccaagtccggtgcc
ttggggacacctgtcacagctgagccggtgccccccgccagcagagcagggccaggtgcg
tccggagggaccggcaaggcccccgccgaggagcccagagcgaggaggcacaagccttcc
tccgagtccccagggagagacaaggggaaactgtccaagctcaaacctgccccaccgccc
ccgccgccggcctccgtggggaaagccgggaagcccgctcagaacccgacccaggaagca
gccggggaggccagcactggcggggaaacgaaaaccgcggccggagcccagcgggggccc
cagccggcgcggcgcccgccccctccacgttgccatcagcagcctccgccctggccgggg
accagcccgcgtctactgccttcatccctctcatatcgacccgcgtgtctcttcggaaaa
cccgccagcctccggagcggatcgccagcggcaccatcaccaagagcgtggtcctggacg
gcaccgaggccctgtgcctggccatctccaagaactccgagcagatggccagccatagcg
ccgtgctggaagccggcaaaaacctgtacacgttctgcgtga
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