Panthera tigris altaica (Amur tiger): 102949666
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Entry
102949666 CDS
T02988
Symbol
GCLC
Name
(RefSeq) glutamate-cysteine ligase catalytic subunit
KO
K11204
glutamate--cysteine ligase catalytic subunit [EC:
6.3.2.2
]
Organism
ptg
Panthera tigris altaica (Amur tiger)
Pathway
ptg00270
Cysteine and methionine metabolism
ptg00480
Glutathione metabolism
ptg01100
Metabolic pathways
ptg01240
Biosynthesis of cofactors
ptg04216
Ferroptosis
Module
ptg_M00118
Glutathione biosynthesis, glutamate => glutathione
Brite
KEGG Orthology (KO) [BR:
ptg00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
102949666 (GCLC)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
102949666 (GCLC)
09140 Cellular Processes
09143 Cell growth and death
04216 Ferroptosis
102949666 (GCLC)
Enzymes [BR:
ptg01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.2 glutamate---cysteine ligase
102949666 (GCLC)
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SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
GCS
GCS2
Motif
Other DBs
NCBI-GeneID:
102949666
NCBI-ProteinID:
XP_015399022
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All DBs
Position
Un
AA seq
754 aa
AA seq
DB search
MVNACPELVTAAVAGIKAHTELSDHSAIVHGPADCHMEQQPGVGDGRVSGVEGRNFAPSS
IPAVTSSTEQAQSAESRGGGTARLEAGPAQSRGEGCITTTTRRAAPAARAASSRYRAALR
ACSARPRVYKIRSYGSRLGAASEQIGRLGMLGGGAGLGHNVLRWGDEVEYMLVSFDHENK
RVQLVLSGEEVLETLQEKGERTNPNHPTLWRPEYGSYMIEGTPGQPYGGTMSEFNTVEDN
MRKRRKEATSLLGENQALCTITSFPRLGCPGFTLPEFKPNPLEGGASKSLFFPDEAINKH
PRFSTLTRNIRHRRGEKVVINVPIFKDKNTPSPFMETFPEDEEAARASKPDHIYMDAMGF
GMGNCCLQVTFQACSISEARYLYDQLATICPIVMALSAASPFYRGYVSDIDCRWGVISAS
VDDRTREERGLEPLKNNSYRISKSRYDSIDSYLSECGEKYNDIDLTIDKEIYEQLLQEGI
DHLLAQHVAHLFIRDPLTLFEEKIHLDDANESDHFENIQSTNWQTMRFKPPPPNSDIGWR
VEFRPMEVQLTDFENSAYVVFVVLLTRVILSYKLDFLIPLSKVDENMKVAQKRDAVLRGM
FYFRKDICKGGNTVVDGYGKAQNTSELTTEDYTLMSIDTIINGKEGVFPGLIPILNSYLE
NMEVDVDTRCSILNYLKLIKKRASGELMTVARWMREFISNHPDYKRDSVITDEMNYSLIL
KCNQIADELCECPELLGPAFRKVKYSGSKTDPSN
NT seq
2265 nt
NT seq
+upstream
nt +downstream
nt
atggttaatgcctgcccagaactggtcactgcagctgtggctggaataaaagcccacaca
gagctctcagatcacagcgccatcgtccatgggcctgccgattgccacatggagcagcag
ccgggtgtgggggatgggagagtgtcaggagtggagggccgaaactttgccccaagcagc
atcccggcagtgacctctagcacagaacaggcacaaagtgctgagtcacggggaggcggc
accgcgcgcctggaggcgggcccggcgcagtcacgtggcgagggctgtatcacaacaacg
acgcggcgtgcagcgccggccgcccgcgccgcttcctcccgctatcgagccgccctccga
gcatgctcagctcggccccgcgtctataaaatccggagctacggatcgcgcctcggagcg
gcgagcgagcagataggaagactgggcatgctcggtggcggcgcaggtcttggtcacaac
gtgctcaggtggggcgacgaggtggaatacatgttggtgtcttttgatcatgaaaataag
agagtccagttggtcctgtctggagaagaagttcttgaaactctacaagaaaagggggaa
aggacaaacccaaaccatcctaccctgtggagaccagagtatggcagttacatgattgaa
ggcacacctggacaaccgtacggaggaacaatgtccgagttcaacacagttgaagacaac
atgagaaaacgccggaaggaggcaacctctttattaggagaaaatcaggctctttgcaca
ataacttcatttcccagattaggctgtcctgggttcacgctgccagagtttaaacccaat
ccgctcgaaggaggagcttccaagtccctcttctttcctgatgaagccataaacaagcat
ccccgcttcagtaccctgacaagaaatatccgacacaggagaggagaaaaggttgtcatc
aatgtaccaatatttaaggacaagaatacaccatctccatttatggaaacatttcctgag
gatgaggaggcagcaagggcttccaagcctgatcatatttacatggatgccatgggattt
gggatgggtaattgctgtcttcaggtaacgttccaagcctgcagcatatctgaggctaga
tacctttatgatcagctggccaccatctgtccaattgtcatggctttgagtgctgcgtct
cctttttaccgaggctatgtgtcagacattgattgtcgctggggagtgatttctgcatct
gtagatgatagaactcgggaggagagaggactggagccactgaagaacaatagctatagg
atcagtaaatcccgatatgattcaatagacagttacttatctgagtgtggggagaaatac
aatgacattgacttgacaattgataaagaaatctacgaacagctgctgcaggaaggcatt
gatcatctcctggcccagcatgtcgctcatctcttcatcagagacccactgactctattc
gaagagaaaatacacttggatgatgccaatgaatcggaccattttgagaacattcagtcc
acaaattggcagacaatgagatttaagccccctcctccaaactctgacattggatggaga
gtagaattccgacccatggaggttcagttaacagactttgagaactctgcatatgtggta
tttgtggtgctgcttacaagagtgatcctttcatacaaactggattttctcattccacta
tcaaaggttgatgaaaacatgaaagttgcacagaaacgagatgctgtcttgcggggaatg
ttttatttcaggaaagatatttgcaaaggtgggaacactgtggtggatggctacgggaag
gcccagaacacctcggaactgaccacggaggactacaccctgatgagcatagacaccatc
atcaacgggaaggagggtgtgtttcctgggctgatcccgattctgaactcttaccttgaa
aacatggaggtggatgtggacactagatgtagtattctgaactacttaaagctaattaag
aagagagcatctggagaactaatgacagttgccagatggatgagagagtttatctccaac
catcctgactataagcgagacagtgtaatcactgatgaaatgaactatagcctcatctta
aagtgtaaccaaattgcagacgaattgtgtgagtgcccggagttacttggaccagcgttt
aggaaagtgaaatacagtggaagtaaaacggacccgtccaactga
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