Panthera tigris altaica (Amur tiger): 102949680
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Entry
102949680 CDS
T02988
Symbol
IGF1R
Name
(RefSeq) insulin like growth factor 1 receptor
KO
K05087
insulin-like growth factor 1 receptor [EC:
2.7.10.1
]
Organism
ptg
Panthera tigris altaica (Amur tiger)
Pathway
ptg01521
EGFR tyrosine kinase inhibitor resistance
ptg01522
Endocrine resistance
ptg04010
MAPK signaling pathway
ptg04014
Ras signaling pathway
ptg04015
Rap1 signaling pathway
ptg04066
HIF-1 signaling pathway
ptg04068
FoxO signaling pathway
ptg04081
Hormone signaling
ptg04114
Oocyte meiosis
ptg04140
Autophagy - animal
ptg04144
Endocytosis
ptg04150
mTOR signaling pathway
ptg04151
PI3K-Akt signaling pathway
ptg04152
AMPK signaling pathway
ptg04211
Longevity regulating pathway
ptg04213
Longevity regulating pathway - multiple species
ptg04510
Focal adhesion
ptg04520
Adherens junction
ptg04550
Signaling pathways regulating pluripotency of stem cells
ptg04730
Long-term depression
ptg04913
Ovarian steroidogenesis
ptg04914
Progesterone-mediated oocyte maturation
ptg05200
Pathways in cancer
ptg05202
Transcriptional misregulation in cancer
ptg05205
Proteoglycans in cancer
ptg05214
Glioma
ptg05215
Prostate cancer
ptg05218
Melanoma
ptg05224
Breast cancer
ptg05225
Hepatocellular carcinoma
Brite
KEGG Orthology (KO) [BR:
ptg00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
102949680 (IGF1R)
04014 Ras signaling pathway
102949680 (IGF1R)
04015 Rap1 signaling pathway
102949680 (IGF1R)
04066 HIF-1 signaling pathway
102949680 (IGF1R)
04068 FoxO signaling pathway
102949680 (IGF1R)
04151 PI3K-Akt signaling pathway
102949680 (IGF1R)
04152 AMPK signaling pathway
102949680 (IGF1R)
04150 mTOR signaling pathway
102949680 (IGF1R)
09133 Signaling molecules and interaction
04081 Hormone signaling
102949680 (IGF1R)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
102949680 (IGF1R)
04140 Autophagy - animal
102949680 (IGF1R)
09143 Cell growth and death
04114 Oocyte meiosis
102949680 (IGF1R)
09144 Cellular community - eukaryotes
04510 Focal adhesion
102949680 (IGF1R)
04520 Adherens junction
102949680 (IGF1R)
04550 Signaling pathways regulating pluripotency of stem cells
102949680 (IGF1R)
09150 Organismal Systems
09152 Endocrine system
04913 Ovarian steroidogenesis
102949680 (IGF1R)
04914 Progesterone-mediated oocyte maturation
102949680 (IGF1R)
09156 Nervous system
04730 Long-term depression
102949680 (IGF1R)
09149 Aging
04211 Longevity regulating pathway
102949680 (IGF1R)
04213 Longevity regulating pathway - multiple species
102949680 (IGF1R)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
102949680 (IGF1R)
05202 Transcriptional misregulation in cancer
102949680 (IGF1R)
05205 Proteoglycans in cancer
102949680 (IGF1R)
09162 Cancer: specific types
05225 Hepatocellular carcinoma
102949680 (IGF1R)
05214 Glioma
102949680 (IGF1R)
05218 Melanoma
102949680 (IGF1R)
05215 Prostate cancer
102949680 (IGF1R)
05224 Breast cancer
102949680 (IGF1R)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
102949680 (IGF1R)
01522 Endocrine resistance
102949680 (IGF1R)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
ptg01001
]
102949680 (IGF1R)
09183 Protein families: signaling and cellular processes
04090 CD molecules [BR:
ptg04090
]
102949680 (IGF1R)
Enzymes [BR:
ptg01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
102949680 (IGF1R)
Protein kinases [BR:
ptg01001
]
Receptor tyrosine kinases (RTK)
INSR family [OT]
102949680 (IGF1R)
CD molecules [BR:
ptg04090
]
Proteins
102949680 (IGF1R)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
Recep_L_domain
fn3
Ig_DSCAM-DSCAML_C
Kinase-like
Motif
Other DBs
NCBI-GeneID:
102949680
NCBI-ProteinID:
XP_007078312
LinkDB
All DBs
Position
Un
AA seq
1049 aa
AA seq
DB search
MYCIPCEGPCPKVCEEEKKTKTIDSVTSAQMLQGCTIFKGNLLINIRRGNNIASELENFM
GLIEVVTGYVKIRHSHALVSLSFLKNLRQILGEEQLEGNYSFYVLDNQNLQQLWDWGHRN
LTIKAGKMYFAFNPKLCVSEIYRMEEVTGTKGRQSKGDINTRNNGERASCESDVLHFTST
TTWKNRIIITWHRYRPPDYRDLISFTVYYKEAPFKNVTEYDGQDACGSNSWNMVDVDLPP
NKDVEPGILLHGLKPWTQYAVYVKAVTLTMVENDHIRGAKSEILYIRTNASVPSIPLDVL
SASNSSSQLIVKWNPPSLPNGNLSYYIVRWQRQPQDSYLYRHNYCSKDKIPIRKYADGTI
DVEEVTENPKTEVCGGEKGPCCACPKTEAEKQAEKEEAEYRKVFENFLHNSIFVPRPERK
RRDVTQVTNTTMSSRSRNITVADTYNITDPEELETEYPFFESRVDNKERTVISNLRPFTL
YRIDIHSCNHEAEKLGCSASNFVFARTMPAEGADDIPGPVTWESRPENSIFLKWPEPENP
NGLILMYEIKYGSQIEDQRECVSRQEYRKYGGAKLNRLNPGNYTARIQATSLSGNGSWTD
PVFFYVPAKITYENFIHLIIALPVAVLLIVGGLVIMLYVFHRKRNNSRLGNGVLYASVNP
EYFSAADVYVPDEWEVAREKITMSRELGQGSFGMVYEGVAKGVVKDEPETRVAIKTVNEA
ASMRERIEFLNEASVMKEFNCHHVVRLLGVVSQGQPTLVIMELMTRGDLKSYLRSLRPEI
ENNPVLAPPSLSKMIQMAGEIADGMAYLNANKFVHRDLAARNCMVAEDFTVKIGDFGMTR
DIYETDYYRKGGKGLLPVRWMSPESLKDGVFTTHSDVWSFGVVLWEIATLAEQPYQGLSN
EQVLRFVMEGGLLDKPDNCPDMLFELMRMCWQYNPKMRPSFLEIISSIKDEMEPGFREVS
FYYSEENKPPEPEELDLEPEDMESVPLDPSASSSSLPLPDRHSGHKAENGPGPGVLVLRA
SFDERQPYAHMNGGRKNERALPLPQSSTC
NT seq
3150 nt
NT seq
+upstream
nt +downstream
nt
atgtactgcatcccttgtgaaggtccttgccccaaggtctgcgaggaggagaagaaaaca
aagaccattgattctgttacctctgctcaaatgctccaaggatgcaccatcttcaagggc
aatctgctcattaatatccgccgaggcaataacattgcctcggagctggagaacttcatg
ggactcatcgaggtggtgacaggctacgtgaagatccgccattcccacgccttggtctcc
ttgtccttcctcaaaaaccttcgccagatcttaggagaggagcagctggaggggaactac
tctttctatgtcctcgacaaccagaacctgcagcagctctgggactggggccaccgcaac
ctgaccatcaaagctgggaagatgtactttgctttcaaccccaagttgtgcgtctccgaa
atttaccgcatggaggaggtgaccgggactaaggggcgccagagcaaaggggacatcaat
acgaggaacaacggagagcgagcctcctgtgaaagtgacgtcctgcacttcacctctacg
accacgtggaagaaccgcatcatcataacctggcaccggtaccggccccctgactacagg
gacctcatcagcttcaccgtctactacaaggaggcaccttttaaaaacgtcacggagtat
gatggccaggatgcctgtggctccaacagctggaacatggtagatgtggacctccctccc
aacaaggacgtcgagcctggcattttactgcatggactaaagccttggacgcagtatgct
gtttacgtcaaggcggtgaccctcaccatggtggagaatgaccatatccgcggggccaag
agtgaaatcttgtacattcgcaccaatgcttcagttccttccattcccctggatgttctt
tcggcatcaaactcctcttctcagctcatcgtgaagtggaacccgccgtccctgcccaac
ggcaacctgagttactacatcgtgaggtggcagcggcagccccaggacagctacctttac
cgccacaactactgctccaaagacaaaatccccatcaggaagtatgccgatggcacaatt
gacgtcgaggaggtgaccgagaaccccaagaccgaagtgtgcggcggagagaaggggcct
tgctgtgcctgccccaaaaccgaggccgagaagcaggcggagaaggaggaggctgagtac
cgcaaagtcttcgagaacttcctgcacaactccatctttgtgcccagacctgaaaggaag
cggagagatgtcacacaagtcaccaacaccaccatgtccagccgaagcaggaacatcacg
gtggcggacacctataatatcacagaccccgaagagctcgagacagaataccctttcttt
gagagcagagtggataacaaggagagaactgtgatctccaacctccggcctttcactttg
taccgcattgacatccacagctgtaaccacgaggctgagaagctgggctgcagcgcctcc
aactttgtctttgcaagaaccatgcctgcagaaggagcagacgacattcctgggccggtg
acctgggagtcaaggcctgaaaactccatctttttaaagtggccggaacctgagaatccc
aatggactgattctaatgtatgaaataaaatatggatcacaaatcgaggatcagcgggaa
tgtgtatccagacaggagtaccggaagtatggaggcgccaagcttaaccggctcaacccg
gggaactatacggcccggatccaggccacctctctctctggaaatgggtcgtggacggat
cccgtgttcttctacgtccccgccaaaataacatatgaaaatttcatccacctgatcatc
gctctgcctgttgccgtcctgctgatagtggggggactggttatcatgttgtacgtcttc
cacagaaaaagaaataacagcaggctggggaatggagtgctgtatgcttcggtgaaccca
gagtacttcagtgccgcagatgtgtatgtacctgatgagtgggaggttgctcgggagaaa
atcaccatgagccgagagctggggcagggctcgtttgggatggtctacgaaggagttgcc
aaaggcgtggttaaagatgagcccgaaaccagggtggccatcaaaacggtgaacgaggcc
gcgagcatgcgtgaaaggattgaatttctcaacgaggcttcagtgatgaaggagttcaat
tgtcaccatgtggtgcggttgctgggcgtggtgtcccagggccagccgacgctggtcatc
atggaactgatgacgcggggcgatctcaaaagttatctcaggtctctgaggccagaaata
gagaataatccagtcctagcacctccaagcctaagcaagatgatccagatggctggagag
attgcagacggcatggcatacctcaacgccaacaagtttgtccacagggaccttgctgcc
cggaactgcatggtggctgaagatttcacggtcaaaatcggagatttcggtatgacgaga
gatatctacgagacagactattaccggaaaggagggaaggggctgctgcctgtgcgctgg
atgtcacccgagtccctcaaggatggggtcttcaccactcactctgacgtctggtccttc
ggggtcgttctctgggagatcgccacgctggccgagcagccgtaccagggcttgtccaac
gagcaagtccttcgcttcgtcatggagggcggccttctggacaagccggacaactgcccc
gacatgctgtttgaactgatgcgcatgtgctggcagtacaaccccaagatgaggccttcc
ttcctggagatcatcagcagcatcaaggacgagatggaacccggcttccgggaggtctcc
ttctactacagcgaggagaacaagccgcccgagccggaggagctggatctggagccggag
gacatggagagcgtccccctggacccctccgcctcctcgtcctccctgccgctgcccgac
agacactcaggacacaaggccgagaacggcccgggccccggcgtgctggttctccgagcc
agcttcgacgagagacagccttacgcgcacatgaacgggggacgcaagaacgagagggcc
ttgcctctgccccagtcttcgacctgctga
DBGET
integrated database retrieval system
