KEGG   Panthera tigris altaica (Amur tiger): 102950020
Entry
102950020         CDS       T02988                                 
Symbol
TGFBR1
Name
(RefSeq) transforming growth factor beta receptor 1
  KO
K04674  TGF-beta receptor type-1 [EC:2.7.11.30]
Organism
ptg  Panthera tigris altaica (Amur tiger)
Pathway
ptg04010  MAPK signaling pathway
ptg04060  Cytokine-cytokine receptor interaction
ptg04068  FoxO signaling pathway
ptg04144  Endocytosis
ptg04218  Cellular senescence
ptg04350  TGF-beta signaling pathway
ptg04371  Apelin signaling pathway
ptg04380  Osteoclast differentiation
ptg04390  Hippo signaling pathway
ptg04520  Adherens junction
ptg04659  Th17 cell differentiation
ptg04926  Relaxin signaling pathway
ptg04933  AGE-RAGE signaling pathway in diabetic complications
ptg05142  Chagas disease
ptg05161  Hepatitis B
ptg05166  Human T-cell leukemia virus 1 infection
ptg05200  Pathways in cancer
ptg05210  Colorectal cancer
ptg05212  Pancreatic cancer
ptg05220  Chronic myeloid leukemia
ptg05225  Hepatocellular carcinoma
ptg05226  Gastric cancer
ptg05415  Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:ptg00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    102950020 (TGFBR1)
   04350 TGF-beta signaling pathway
    102950020 (TGFBR1)
   04390 Hippo signaling pathway
    102950020 (TGFBR1)
   04371 Apelin signaling pathway
    102950020 (TGFBR1)
   04068 FoxO signaling pathway
    102950020 (TGFBR1)
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    102950020 (TGFBR1)
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    102950020 (TGFBR1)
  09143 Cell growth and death
   04218 Cellular senescence
    102950020 (TGFBR1)
  09144 Cellular community - eukaryotes
   04520 Adherens junction
    102950020 (TGFBR1)
 09150 Organismal Systems
  09151 Immune system
   04659 Th17 cell differentiation
    102950020 (TGFBR1)
  09152 Endocrine system
   04926 Relaxin signaling pathway
    102950020 (TGFBR1)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    102950020 (TGFBR1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    102950020 (TGFBR1)
  09162 Cancer: specific types
   05210 Colorectal cancer
    102950020 (TGFBR1)
   05212 Pancreatic cancer
    102950020 (TGFBR1)
   05225 Hepatocellular carcinoma
    102950020 (TGFBR1)
   05226 Gastric cancer
    102950020 (TGFBR1)
   05220 Chronic myeloid leukemia
    102950020 (TGFBR1)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    102950020 (TGFBR1)
   05161 Hepatitis B
    102950020 (TGFBR1)
  09174 Infectious disease: parasitic
   05142 Chagas disease
    102950020 (TGFBR1)
  09166 Cardiovascular disease
   05415 Diabetic cardiomyopathy
    102950020 (TGFBR1)
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    102950020 (TGFBR1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:ptg01001]
    102950020 (TGFBR1)
Enzymes [BR:ptg01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.30  receptor protein serine/threonine kinase
     102950020 (TGFBR1)
Protein kinases [BR:ptg01001]
 Receptor serine/threonine kinases (RSTK): TKL group
  TGFBR1 family [OT]
   102950020 (TGFBR1)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr TGF_beta_GS Activin_recp Pkinase_fungal APH FTA2 Haspin_kinase
Other DBs
NCBI-GeneID: 102950020
NCBI-ProteinID: XP_015396197
LinkDB
Position
Un
AA seq 485 aa
MVEEFFLIESSLFPALQCFCHLCTKDNFTCVTDGLCFVSVTETTDKVIHNSMCIAEIDLI
PRDRPFVCAPSSKTGSVTTTYCCNQDHCNKIELPTVGKPSSGLGPVELAAVIAGPVCFVC
ISLMLMVYICHNRTVIHHRVPNEEDPSLDRPFISEGTTLKDLIYDMTTSGSGSGLPLLVQ
RTIARTIVLQESIGKGRFGEVWRGKWRGEEVAVKIFSSREERSWFREAEIYQTVMLRHEN
ILGFIAADNKDNGTWTQLWLVSDYHEHGSLFDYLNRYTVTVEGMIKLALSTASGLAHLHM
EIVGTQGKPAIAHRDLKSKNILVKKNGTCCIADLGLAVRHDSATDTIDIAPNHRVGTKRY
MAPEVLDDSINMKHFESFKRADIYAMGLVFWEIARRCSIGGIHEDYQLPYYDLVPSDPSV
EEMRKVVCEQKLRPNIPNRWQSCEALRVMAKIMRECWYANGAARLTALRIKKTLSQLSQQ
EGIKM
NT seq 1458 nt   +upstreamnt  +downstreamnt
atggtggaagaattttttctaatagaatcttctcttttcccagcattacagtgtttctgc
cacctttgtacaaaagacaattttacttgtgtgacagatgggctctgctttgtctctgtc
acagagaccacagacaaagttatacacaatagcatgtgtatagctgaaattgacctaatt
ccccgagacaggccgtttgtgtgtgcaccgtcttcaaaaaccggctctgtcactacaacg
tattgctgcaatcaggaccactgcaataaaatagaactcccgactgttggaaagccatca
tctggccttggtcccgtcgaattggcagctgtcattgctggaccagtctgcttcgtctgc
atctcactcatgttaatggtttatatctgccataatcgtactgtcattcaccatcgagtg
ccaaacgaagaggatccttccttagatcgtccttttatttcagagggcactacgttgaaa
gatttaatttatgatatgacaacatcgggttctggatcaggtttaccattgctcgttcag
agaacaattgcaagaactattgtgttacaagaaagtattggcaaaggtcgatttggagaa
gtttggcggggaaaatggcgaggagaagaagttgctgtcaaaatattctcctctagagaa
gaacgctcatggttccgtgaggccgagatttatcagaccgtaatgttacgccatgaaaac
atcttgggatttatagcggcagacaataaagacaacggtacatggactcagctctggttg
gtgtcagattatcatgagcatggatccctttttgattatttgaacagatacacagtgacc
gtggaaggaatgataaaactcgctttgtccacagcaagtggacttgcccatcttcacatg
gagattgttggtacccaagggaaaccagccattgctcatagagatttgaagtccaagaat
atcttagtaaagaagaatggaacttgctgcattgcagacttaggactggcagtaagacac
gattcagccacagatacgattgatattgctccaaaccacagagtgggaacaaaaaggtac
atggcccccgaagttctagatgattccataaacatgaaacactttgaatccttcaaacgt
gctgacatctatgcaatgggcttagtattctgggaaatagctcgacgatgttccattggt
ggaattcatgaagattaccagctgccttattatgatcttgtaccttctgatccatcagtt
gaagaaatgaggaaagttgtttgtgaacagaagttaaggccaaatattccaaacagatgg
cagagttgtgaagccttgagagtaatggctaaaattatgagagaatgttggtatgccaac
ggagctgctagacttacagctttgaggattaagaaaacattgtcacaactcagtcaacag
gaaggcatcaaaatgtag

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