Panthera tigris altaica (Amur tiger): 102950765
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Entry
102950765 CDS
T02988
Symbol
SHMT2
Name
(RefSeq) serine hydroxymethyltransferase 2
KO
K00600
glycine hydroxymethyltransferase [EC:
2.1.2.1
]
Organism
ptg
Panthera tigris altaica (Amur tiger)
Pathway
ptg00260
Glycine, serine and threonine metabolism
ptg00630
Glyoxylate and dicarboxylate metabolism
ptg00670
One carbon pool by folate
ptg01100
Metabolic pathways
ptg01200
Carbon metabolism
ptg01230
Biosynthesis of amino acids
ptg01240
Biosynthesis of cofactors
ptg01523
Antifolate resistance
ptg04981
Folate transport and metabolism
Module
ptg_M00141
C1-unit interconversion, eukaryotes
Brite
KEGG Orthology (KO) [BR:
ptg00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00630 Glyoxylate and dicarboxylate metabolism
102950765 (SHMT2)
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
102950765 (SHMT2)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
102950765 (SHMT2)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
102950765 (SHMT2)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
102950765 (SHMT2)
Enzymes [BR:
ptg01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.1 glycine hydroxymethyltransferase
102950765 (SHMT2)
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Ortholog
Paralog
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Motif
Pfam:
SHMT
Aminotran_1_2
Motif
Other DBs
NCBI-GeneID:
102950765
NCBI-ProteinID:
XP_007081592
UniProt:
A0A8C9M4Q7
LinkDB
All DBs
Position
Un
AA seq
504 aa
AA seq
DB search
MLPFSLLWATRPLQRWGHLGRMAIRCQHSEVAQTQTGEATRGWTGQESLSDSDPEMWELL
QREKDRQCRGLELIASENFCSRAALEALGSCLNNKYSEGYPGKRYYGGAEVVDEIELLCQ
RRALEAFDLDPAQWGVNVQPYSGSPANLAAYTALLQPHDRIMGLDLPDGGHLTHGYMSDV
KRISATSIFFESMPYKLNPKTGLIDYDQLALTARLFRPRLIIAGTSAYARLIDYARMREV
CDEVKAHLLADMAHISGLVAAKVIPSPFKHADVVTTTTHKTLRGARSGLIFYRKGMQAVD
PKTGREIPYTFEDRINFAVFPSLQGGPHNHAIAAVAVALKQACTPTFREYALQVLKNARA
MADALLERGYSLVSGGTDNHLVLVDLRPKGLDGARAERVLELVSITANKNTCPGDRSAIT
PGGLRLGAPALTSRQFREDDFRRVVDFIDEGVNIGLEVKSKTAKLQDFKSFLLKDTETSH
RLADLRQRVEQFARAFPMPGFDER
NT seq
1515 nt
NT seq
+upstream
nt +downstream
nt
atgctgcccttctctttgctctgggcgactcggcctctgcagagatggggtcatctgggc
aggatggccatacggtgccaacacagtgaggtggcccagacccagactggagaagcaacc
aggggctggacaggccaagagagtctgtcagacagtgaccctgagatgtgggagctgctg
cagagagagaaggacaggcagtgtcgtggcctggagctcattgcctcagagaacttctgc
agccgagctgcgctggaggccttggggtcctgtctgaacaacaagtactcggagggttat
cctggcaagagatattatggaggagcagaggtagtggatgaaattgagctgctgtgtcag
cgccgggccttggaagcctttgacctggatcctgcacagtggggagtcaatgtccagcca
tactcaggctctccggctaatctggcggcctatacagcccttctgcagcctcatgaccga
atcatggggctggacttgcctgatgggggccatcttactcacggctacatgtctgatgtc
aagcggatctcggccacatccattttctttgagtctatgccctataagttaaatcccaaa
actggcctcatcgactatgaccagctggcactgaccgctcggcttttccgaccgcggctc
attatagctggtaccagtgcctacgctcgcctcattgactacgcccgcatgagagaggtg
tgtgatgaggtcaaggcacacctcctggcagacatggcccacatcagtggcctggtggct
gccaaggtgatcccctcacctttcaagcacgcggatgttgtcaccaccaccactcacaag
acccttcgaggggccaggtcaggactcatcttctaccggaaggggatgcaggctgtggac
cccaagaccggccgggagatcccttacacatttgaggaccgaatcaactttgctgtgttc
ccgtccctgcagggggggccccacaaccatgccattgctgcagtggctgtggccttaaag
caggcctgcacccccacgttccgggagtacgccctgcaggttctgaagaatgctcgggcc
atggccgatgccctgctagagcgaggctactcgctcgtgtctggtggcaccgacaatcac
ctagtgctggtggacctgcggcccaagggcctggatggagctcgggctgagcgggtgctg
gaacttgtatccatcacagccaacaagaacacctgtcccggagaccgaagtgccatcaca
cctgggggcctgcggcttggggccccagccttgacatctcgacagttccgtgaggatgac
ttccggagagttgtagactttatagatgaaggggtcaacatcggcttggaggtgaagagc
aaaactgccaaactccaggatttcaaatccttcctgctcaaggacacagaaaccagtcat
cggctggccgacctccggcaacgggtggaacagtttgccagggccttccccatgcctggt
tttgatgagcgctga
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