Panthera tigris altaica (Amur tiger): 102950880
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Entry
102950880 CDS
T02988
Symbol
MAPK8
Name
(RefSeq) mitogen-activated protein kinase 8
KO
K04440
mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:
2.7.11.24
]
Organism
ptg
Panthera tigris altaica (Amur tiger)
Pathway
ptg01522
Endocrine resistance
ptg04010
MAPK signaling pathway
ptg04012
ErbB signaling pathway
ptg04014
Ras signaling pathway
ptg04024
cAMP signaling pathway
ptg04068
FoxO signaling pathway
ptg04071
Sphingolipid signaling pathway
ptg04137
Mitophagy - animal
ptg04140
Autophagy - animal
ptg04141
Protein processing in endoplasmic reticulum
ptg04210
Apoptosis
ptg04215
Apoptosis - multiple species
ptg04217
Necroptosis
ptg04310
Wnt signaling pathway
ptg04380
Osteoclast differentiation
ptg04510
Focal adhesion
ptg04530
Tight junction
ptg04620
Toll-like receptor signaling pathway
ptg04621
NOD-like receptor signaling pathway
ptg04622
RIG-I-like receptor signaling pathway
ptg04625
C-type lectin receptor signaling pathway
ptg04657
IL-17 signaling pathway
ptg04658
Th1 and Th2 cell differentiation
ptg04659
Th17 cell differentiation
ptg04660
T cell receptor signaling pathway
ptg04664
Fc epsilon RI signaling pathway
ptg04668
TNF signaling pathway
ptg04722
Neurotrophin signaling pathway
ptg04723
Retrograde endocannabinoid signaling
ptg04728
Dopaminergic synapse
ptg04750
Inflammatory mediator regulation of TRP channels
ptg04910
Insulin signaling pathway
ptg04912
GnRH signaling pathway
ptg04914
Progesterone-mediated oocyte maturation
ptg04917
Prolactin signaling pathway
ptg04920
Adipocytokine signaling pathway
ptg04926
Relaxin signaling pathway
ptg04930
Type II diabetes mellitus
ptg04931
Insulin resistance
ptg04932
Non-alcoholic fatty liver disease
ptg04933
AGE-RAGE signaling pathway in diabetic complications
ptg04935
Growth hormone synthesis, secretion and action
ptg04936
Alcoholic liver disease
ptg05010
Alzheimer disease
ptg05012
Parkinson disease
ptg05016
Huntington disease
ptg05017
Spinocerebellar ataxia
ptg05020
Prion disease
ptg05022
Pathways of neurodegeneration - multiple diseases
ptg05132
Salmonella infection
ptg05133
Pertussis
ptg05135
Yersinia infection
ptg05142
Chagas disease
ptg05145
Toxoplasmosis
ptg05152
Tuberculosis
ptg05161
Hepatitis B
ptg05162
Measles
ptg05166
Human T-cell leukemia virus 1 infection
ptg05167
Kaposi sarcoma-associated herpesvirus infection
ptg05169
Epstein-Barr virus infection
ptg05170
Human immunodeficiency virus 1 infection
ptg05171
Coronavirus disease - COVID-19
ptg05200
Pathways in cancer
ptg05208
Chemical carcinogenesis - reactive oxygen species
ptg05210
Colorectal cancer
ptg05212
Pancreatic cancer
ptg05231
Choline metabolism in cancer
ptg05415
Diabetic cardiomyopathy
ptg05417
Lipid and atherosclerosis
ptg05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
ptg00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04141 Protein processing in endoplasmic reticulum
102950880 (MAPK8)
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
102950880 (MAPK8)
04012 ErbB signaling pathway
102950880 (MAPK8)
04014 Ras signaling pathway
102950880 (MAPK8)
04310 Wnt signaling pathway
102950880 (MAPK8)
04668 TNF signaling pathway
102950880 (MAPK8)
04068 FoxO signaling pathway
102950880 (MAPK8)
04071 Sphingolipid signaling pathway
102950880 (MAPK8)
04024 cAMP signaling pathway
102950880 (MAPK8)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
102950880 (MAPK8)
04137 Mitophagy - animal
102950880 (MAPK8)
09143 Cell growth and death
04210 Apoptosis
102950880 (MAPK8)
04215 Apoptosis - multiple species
102950880 (MAPK8)
04217 Necroptosis
102950880 (MAPK8)
09144 Cellular community - eukaryotes
04510 Focal adhesion
102950880 (MAPK8)
04530 Tight junction
102950880 (MAPK8)
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
102950880 (MAPK8)
04621 NOD-like receptor signaling pathway
102950880 (MAPK8)
04622 RIG-I-like receptor signaling pathway
102950880 (MAPK8)
04625 C-type lectin receptor signaling pathway
102950880 (MAPK8)
04660 T cell receptor signaling pathway
102950880 (MAPK8)
04658 Th1 and Th2 cell differentiation
102950880 (MAPK8)
04659 Th17 cell differentiation
102950880 (MAPK8)
04657 IL-17 signaling pathway
102950880 (MAPK8)
04664 Fc epsilon RI signaling pathway
102950880 (MAPK8)
09152 Endocrine system
04910 Insulin signaling pathway
102950880 (MAPK8)
04920 Adipocytokine signaling pathway
102950880 (MAPK8)
04912 GnRH signaling pathway
102950880 (MAPK8)
04914 Progesterone-mediated oocyte maturation
102950880 (MAPK8)
04917 Prolactin signaling pathway
102950880 (MAPK8)
04926 Relaxin signaling pathway
102950880 (MAPK8)
04935 Growth hormone synthesis, secretion and action
102950880 (MAPK8)
09156 Nervous system
04728 Dopaminergic synapse
102950880 (MAPK8)
04723 Retrograde endocannabinoid signaling
102950880 (MAPK8)
04722 Neurotrophin signaling pathway
102950880 (MAPK8)
09157 Sensory system
04750 Inflammatory mediator regulation of TRP channels
102950880 (MAPK8)
09158 Development and regeneration
04380 Osteoclast differentiation
102950880 (MAPK8)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
102950880 (MAPK8)
05208 Chemical carcinogenesis - reactive oxygen species
102950880 (MAPK8)
05231 Choline metabolism in cancer
102950880 (MAPK8)
09162 Cancer: specific types
05210 Colorectal cancer
102950880 (MAPK8)
05212 Pancreatic cancer
102950880 (MAPK8)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
102950880 (MAPK8)
05170 Human immunodeficiency virus 1 infection
102950880 (MAPK8)
05161 Hepatitis B
102950880 (MAPK8)
05171 Coronavirus disease - COVID-19
102950880 (MAPK8)
05162 Measles
102950880 (MAPK8)
05167 Kaposi sarcoma-associated herpesvirus infection
102950880 (MAPK8)
05169 Epstein-Barr virus infection
102950880 (MAPK8)
09171 Infectious disease: bacterial
05132 Salmonella infection
102950880 (MAPK8)
05135 Yersinia infection
102950880 (MAPK8)
05133 Pertussis
102950880 (MAPK8)
05152 Tuberculosis
102950880 (MAPK8)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
102950880 (MAPK8)
05142 Chagas disease
102950880 (MAPK8)
09164 Neurodegenerative disease
05010 Alzheimer disease
102950880 (MAPK8)
05012 Parkinson disease
102950880 (MAPK8)
05016 Huntington disease
102950880 (MAPK8)
05017 Spinocerebellar ataxia
102950880 (MAPK8)
05020 Prion disease
102950880 (MAPK8)
05022 Pathways of neurodegeneration - multiple diseases
102950880 (MAPK8)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
102950880 (MAPK8)
05418 Fluid shear stress and atherosclerosis
102950880 (MAPK8)
05415 Diabetic cardiomyopathy
102950880 (MAPK8)
09167 Endocrine and metabolic disease
04930 Type II diabetes mellitus
102950880 (MAPK8)
04936 Alcoholic liver disease
102950880 (MAPK8)
04932 Non-alcoholic fatty liver disease
102950880 (MAPK8)
04931 Insulin resistance
102950880 (MAPK8)
04933 AGE-RAGE signaling pathway in diabetic complications
102950880 (MAPK8)
09176 Drug resistance: antineoplastic
01522 Endocrine resistance
102950880 (MAPK8)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
ptg01001
]
102950880 (MAPK8)
Enzymes [BR:
ptg01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.24 mitogen-activated protein kinase
102950880 (MAPK8)
Protein kinases [BR:
ptg01001
]
Serine/threonine kinases: CMGC group
MAPK family [OT]
102950880 (MAPK8)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
Kdo
ABC1
RIO1
Kinase-like
FTA2
APH
DUF530
Motif
Other DBs
NCBI-GeneID:
102950880
NCBI-ProteinID:
XP_007080075
LinkDB
All DBs
Position
Un
AA seq
427 aa
AA seq
DB search
MSRSKRDSNFYSVEIGDSTFTVLKRYQNLKPIGSGAQGIVCAAYDAILERNVAIKKLSRP
FQNQTHAKRAYRELVLMKCVNHKNIIGLLNVFTPQKSLEEFQDVYIVMELMDANLCQVIQ
MELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSF
MMTPYVVTRYYRAPEVILGMGYKENVDIWSVGCIMGEMIKGGVLFPGTDHIDQWNKVIEQ
LGTPCPEFMKKLQPTVRTYVENRPKYAGYSFEKLFPDVLFPADSEHNKLKASQARDLLSK
MLVIDASKRISVDEALQHPYINVWYDPSEAEAPPPKIPDKQLDEREHTIEEWKELIYKEV
MDLEERTKNGVIRGQPSPLGAAVINGSQHPSSSSSVNDVSSMSTDPTLASDTDSSLEASA
GPLGCCR
NT seq
1284 nt
NT seq
+upstream
nt +downstream
nt
atgagcagaagcaagcgtgacagcaatttttatagtgtagagattggagattctacattt
acagttttgaaacgatatcagaatttaaaacctataggctcaggagctcaaggaattgta
tgtgcagcttatgatgccattcttgaaagaaatgttgcaatcaagaagctgagccggccg
tttcagaatcagacccatgctaaacgggcttacagagagctagttctaatgaaatgtgtt
aatcacaaaaatataattggccttttgaatgttttcacaccacagaaatccctagaagaa
tttcaagatgtttacatagtcatggagctcatggatgcaaatctttgccaagtgattcag
atggaactagatcatgaaagaatgtcctaccttctctatcagatgctgtgtggaatcaag
caccttcactctgctggaattattcatcgggacttaaagcccagtaatatagtggtaaaa
tcagactgcactttgaagattcttgactttggactggccaggactgcaggaactagtttt
atgatgacgccttacgtagtgactcgctactacagagcacctgaggtcatcctagggatg
ggctacaaagaaaacgttgacatttggtcagttgggtgcatcatgggagaaatgatcaaa
ggtggtgttttgttcccaggtacagatcatattgatcagtggaataaagttattgaacag
cttggaacaccatgccctgaattcatgaagaaactacaaccaacagtaaggacttacgtt
gaaaacagacctaaatatgctggatatagctttgagaaactcttccccgatgtacttttc
ccagctgactcggaacacaacaaacttaaagccagtcaggcaagggacttgttatccaaa
atgctggtaattgatgcatctaaaaggatctctgtagacgaagccctccagcatccatat
atcaatgtctggtatgatccttctgaagcagaagctccaccacccaagatacctgacaag
caattagatgaaagggaacatacaatagaagagtggaaagagttgatatacaaagaagtt
atggacttggaggagagaaccaagaatggagttatacgggggcagccctctcctttaggt
gcagcagtgatcaatggctctcagcatccatcgtcatcatcgtctgtcaatgatgtgtct
tcaatgtcaacagatccgactttggcctcagatacagatagcagtctggaagcatcagct
ggacctctgggctgttgtagatga
DBGET
integrated database retrieval system