KEGG   Panthera tigris altaica (Amur tiger): 102952318
Entry
102952318         CDS       T02988                                 
Symbol
HGF
Name
(RefSeq) hepatocyte growth factor
  KO
K05460  hepatocyte growth factor
Organism
ptg  Panthera tigris altaica (Amur tiger)
Pathway
ptg01521  EGFR tyrosine kinase inhibitor resistance
ptg04010  MAPK signaling pathway
ptg04014  Ras signaling pathway
ptg04015  Rap1 signaling pathway
ptg04020  Calcium signaling pathway
ptg04151  PI3K-Akt signaling pathway
ptg04510  Focal adhesion
ptg05144  Malaria
ptg05200  Pathways in cancer
ptg05205  Proteoglycans in cancer
ptg05208  Chemical carcinogenesis - reactive oxygen species
ptg05211  Renal cell carcinoma
ptg05218  Melanoma
ptg05223  Non-small cell lung cancer
ptg05225  Hepatocellular carcinoma
ptg05226  Gastric cancer
Brite
KEGG Orthology (KO) [BR:ptg00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    102952318 (HGF)
   04014 Ras signaling pathway
    102952318 (HGF)
   04015 Rap1 signaling pathway
    102952318 (HGF)
   04020 Calcium signaling pathway
    102952318 (HGF)
   04151 PI3K-Akt signaling pathway
    102952318 (HGF)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    102952318 (HGF)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    102952318 (HGF)
   05205 Proteoglycans in cancer
    102952318 (HGF)
   05208 Chemical carcinogenesis - reactive oxygen species
    102952318 (HGF)
  09162 Cancer: specific types
   05225 Hepatocellular carcinoma
    102952318 (HGF)
   05226 Gastric cancer
    102952318 (HGF)
   05218 Melanoma
    102952318 (HGF)
   05211 Renal cell carcinoma
    102952318 (HGF)
   05223 Non-small cell lung cancer
    102952318 (HGF)
  09174 Infectious disease: parasitic
   05144 Malaria
    102952318 (HGF)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    102952318 (HGF)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and neuropeptides [BR:ptg04052]
    102952318 (HGF)
   00536 Glycosaminoglycan binding proteins [BR:ptg00536]
    102952318 (HGF)
Cytokines and neuropeptides [BR:ptg04052]
 Cytokines
  Growth factors (RTK binding)
   102952318 (HGF)
Glycosaminoglycan binding proteins [BR:ptg00536]
 Heparan sulfate / Heparin
  Growth factors/receptors
   102952318 (HGF)
SSDB
Motif
Pfam: Kringle Trypsin PAN_1 DUF1986 DUF316 CWC25
Other DBs
NCBI-GeneID: 102952318
NCBI-ProteinID: XP_007076842
LinkDB
Position
Un
AA seq 728 aa
MWVTKLLPVLLLQHVLLHLLLLPIPYAEGQKKRRNTLHEFKKSAKTTLIKEDPLLKIKTK
KMNTADQCANRCIRNKGLPFTCKAFVFDKARKRCLWFPFNSMTSGVKKEFGHEFDLYENK
DYIRNCIIGKGGSYKGTVSITKSGIKCQPWNSMIPHEHSFLPSSYRGKDLQENYCRNPRG
EEGGPWCFTSNPEVRYEVCDIPQCSEVECMTCNGESYRGPVDHTESGKICQRWDLQTPHR
HKFLPERYPDKGFDDNYCRNPDGKPRPWCYTLDPDTPWEYCAIKMCAHSTMNDTDVPMET
TECIQGQGEGYRGTINSIWNGVPCQRWDSQYPHQHDITPENFKCKDLRENFCRNPDGAES
PWCFTTDPNIRVGYCSQIPKCDVSSGQDCYRGNGKNYMGNLSKTRSGLTCSMWEKNMEDL
HRHIFWEPDASKLNKNYCRNPDDDAHGPWCYTGNPLIPWDYCPISRCEGDTTPTIVNLDH
PVISCAKTKQLRVVNGIPTRTNVGWMVSLKYRNKHICGGSLIKESWILTARQCFPSRNKD
LKDYEAWLGIHDVHGRGDEKRKQVLNVSQLVYGPEGSDLVLLKLARPAVLDDFVSTIDLP
NYGCTIPEKTTCSVYGWGYTGSINSDGLLRVAHLYIMGNEKCSQYHQGKVTLNESEICAG
AENIVSGPCEGDYGGPLVCEQHKMRMVLGVIVPGRGCAIPNRPGIFVRVAYYAKWIHKII
LTYKIPQS
NT seq 2187 nt   +upstreamnt  +downstreamnt
atgtgggtgaccaaacttcttccagtcctgctgctgcagcacgtcctcctccacctcctt
ctgcttcccatcccctatgcagaaggacagaagaaaagaagaaacacacttcatgaattc
aaaaagtcagcaaagactactctaattaaagaagacccattactgaagataaaaacaaaa
aaaatgaacactgcagaccaatgtgccaatagatgtattaggaataaaggacttccattc
acttgcaaggcctttgtttttgataaagcaaggaaacgatgcctctggttccctttcaat
agcatgacaagtggagtgaaaaaagagtttggtcatgaattcgatctctatgaaaacaaa
gactacattagaaactgcatcattggcaaaggaggtagctacaagggaacagtatctatc
actaagagtggcatcaaatgccagccttggaattctatgataccacatgaacacagcttt
ttgccttcgagctatcggggtaaagacctacaggaaaactactgtcgaaatcctcgaggg
gaagaagggggaccttggtgtttcacaagcaatccagaggtacgctacgaagtctgtgac
attcctcagtgttcagaagttgaatgcatgacctgcaatggggaaagttatcgaggtccc
gtggatcatacagaatcaggcaagatttgtcagcgctgggatcttcagacaccacaccgg
cacaaattcttgccagaaagatatcccgacaagggctttgatgataattattgccgcaat
cctgatggcaagccgaggccatggtgctatactcttgaccctgacaccccctgggagtac
tgtgcaattaaaatgtgcgctcacagtactatgaatgacacagatgtgcctatggaaaca
actgaatgcattcagggtcaaggagaaggttaccggggcaccatcaactccatctggaat
ggagttccatgtcagcgttgggattcccagtatcctcaccagcatgacataactcctgaa
aatttcaagtgcaaggacctacgagaaaatttttgccgaaatccagatggagctgagtca
ccctggtgttttaccactgatccaaacatccgagttggctactgctcccaaattccaaaa
tgtgatgtgtcaagtggacaagattgttatcgtgggaatggcaaaaattatatgggcaat
ttatccaaaacacgatctggactaacatgttcaatgtgggagaagaacatggaagactta
cacaggcatatcttctgggaaccagatgctagtaagctgaataagaattactgccggaat
cctgatgatgatgcccatggcccctggtgttacacgggaaatcctctcattccatgggat
tattgtcctatttctcgttgtgaaggtgataccacacctacaatagtcaatttagaccat
cccgtaatatcttgtgccaaaacaaaacaactgcgagttgtaaatggaatcccaacgcgg
acaaatgtaggatggatggttagtttgaaatacagaaataaacatatctgtggaggatca
ttgataaaggaaagctggattcttaccgcaagacaatgtttcccttctcgaaacaaagac
ttgaaagattatgaagcttggcttgggattcatgatgtccacggaagaggagatgagaaa
cgcaaacaggttctaaatgtgtcccagctggtatatgggcctgaagggtcagatctggta
ttactgaagcttgctaggcctgctgtcctggatgattttgttagtacaattgatttacct
aattatggatgcaccattcctgaaaaaaccacttgcagtgtttatggctggggttatact
ggatcaatcaactctgatggcctattacgagtagcacatctctatattatggggaatgag
aaatgcagccaataccatcaagggaaggtgactctgaatgagtctgaaatatgtgcaggt
gccgaaaatattgtgtcaggaccatgtgagggagattatggtggcccacttgtttgtgaa
caacataaaatgagaatggttcttggtgtcattgttcctggtcgtggatgtgccattcca
aatcgtcctggcatttttgtccgagtagcatattatgcaaaatggatacacaaaattata
ttaacatataagataccacagtcatag

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