Panthera tigris altaica (Amur tiger): 102952814 Help Entry 102952814         CDS       T02988                                  Symbol PRKCB Name (RefSeq) protein kinase C beta   KO K19662   classical protein kinase C beta type [EC:2.7.11.13] Organism ptg  Panthera tigris altaica (Amur tiger) Pathway ptg01521   EGFR tyrosine kinase inhibitor resistance ptg04010   MAPK signaling pathway ptg04012   ErbB signaling pathway ptg04014   Ras signaling pathway ptg04015   Rap1 signaling pathway ptg04020   Calcium signaling pathway ptg04062   Chemokine signaling pathway ptg04064   NF-kappa B signaling pathway ptg04066   HIF-1 signaling pathway ptg04070   Phosphatidylinositol signaling system ptg04071   Sphingolipid signaling pathway ptg04082   Neuroactive ligand signaling ptg04150   mTOR signaling pathway ptg04270   Vascular smooth muscle contraction ptg04310   Wnt signaling pathway ptg04370   VEGF signaling pathway ptg04510   Focal adhesion ptg04540   Gap junction ptg04613   Neutrophil extracellular trap formation ptg04650   Natural killer cell mediated cytotoxicity ptg04662   B cell receptor signaling pathway ptg04666   Fc gamma R-mediated phagocytosis ptg04670   Leukocyte transendothelial migration ptg04713   Circadian entrainment ptg04720   Long-term potentiation ptg04723   Retrograde endocannabinoid signaling ptg04724   Glutamatergic synapse ptg04725   Cholinergic synapse ptg04726   Serotonergic synapse ptg04727   GABAergic synapse ptg04728   Dopaminergic synapse ptg04730   Long-term depression ptg04750   Inflammatory mediator regulation of TRP channels ptg04911   Insulin secretion ptg04912   GnRH signaling pathway ptg04916   Melanogenesis ptg04918   Thyroid hormone synthesis ptg04919   Thyroid hormone signaling pathway ptg04921   Oxytocin signaling pathway ptg04925   Aldosterone synthesis and secretion ptg04928   Parathyroid hormone synthesis, secretion and action ptg04929   GnRH secretion ptg04931   Insulin resistance ptg04933   AGE-RAGE signaling pathway in diabetic complications ptg04935   Growth hormone synthesis, secretion and action ptg04960   Aldosterone-regulated sodium reabsorption ptg04961   Endocrine and other factor-regulated calcium reabsorption ptg04970   Salivary secretion ptg04971   Gastric acid secretion ptg04972   Pancreatic secretion ptg04973   Carbohydrate digestion and absorption ptg05017   Spinocerebellar ataxia ptg05022   Pathways of neurodegeneration - multiple diseases ptg05031   Amphetamine addiction ptg05032   Morphine addiction ptg05140   Leishmaniasis ptg05143   African trypanosomiasis ptg05146   Amoebiasis ptg05161   Hepatitis B ptg05163   Human cytomegalovirus infection ptg05164   Influenza A ptg05170   Human immunodeficiency virus 1 infection ptg05171   Coronavirus disease - COVID-19 ptg05200   Pathways in cancer ptg05205   Proteoglycans in cancer ptg05206   MicroRNAs in cancer ptg05207   Chemical carcinogenesis - receptor activation ptg05214   Glioma ptg05223   Non-small cell lung cancer ptg05225   Hepatocellular carcinoma ptg05231   Choline metabolism in cancer ptg05415   Diabetic cardiomyopathy Brite KEGG Orthology (KO) [BR:ptg00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     102952814 (PRKCB)    04012 ErbB signaling pathway     102952814 (PRKCB)    04014 Ras signaling pathway     102952814 (PRKCB)    04015 Rap1 signaling pathway     102952814 (PRKCB)    04310 Wnt signaling pathway     102952814 (PRKCB)    04370 VEGF signaling pathway     102952814 (PRKCB)    04064 NF-kappa B signaling pathway     102952814 (PRKCB)    04066 HIF-1 signaling pathway     102952814 (PRKCB)    04020 Calcium signaling pathway     102952814 (PRKCB)    04070 Phosphatidylinositol signaling system     102952814 (PRKCB)    04071 Sphingolipid signaling pathway     102952814 (PRKCB)    04150 mTOR signaling pathway     102952814 (PRKCB)   09133 Signaling molecules and interaction    04082 Neuroactive ligand signaling     102952814 (PRKCB)  09140 Cellular Processes   09144 Cellular community - eukaryotes    04510 Focal adhesion     102952814 (PRKCB)    04540 Gap junction     102952814 (PRKCB)  09150 Organismal Systems   09151 Immune system    04613 Neutrophil extracellular trap formation     102952814 (PRKCB)    04650 Natural killer cell mediated cytotoxicity     102952814 (PRKCB)    04662 B cell receptor signaling pathway     102952814 (PRKCB)    04666 Fc gamma R-mediated phagocytosis     102952814 (PRKCB)    04670 Leukocyte transendothelial migration     102952814 (PRKCB)    04062 Chemokine signaling pathway     102952814 (PRKCB)   09152 Endocrine system    04911 Insulin secretion     102952814 (PRKCB)    04929 GnRH secretion     102952814 (PRKCB)    04912 GnRH signaling pathway     102952814 (PRKCB)    04921 Oxytocin signaling pathway     102952814 (PRKCB)    04935 Growth hormone synthesis, secretion and action     102952814 (PRKCB)    04918 Thyroid hormone synthesis     102952814 (PRKCB)    04919 Thyroid hormone signaling pathway     102952814 (PRKCB)    04928 Parathyroid hormone synthesis, secretion and action     102952814 (PRKCB)    04916 Melanogenesis     102952814 (PRKCB)    04925 Aldosterone synthesis and secretion     102952814 (PRKCB)   09153 Circulatory system    04270 Vascular smooth muscle contraction     102952814 (PRKCB)   09154 Digestive system    04970 Salivary secretion     102952814 (PRKCB)    04971 Gastric acid secretion     102952814 (PRKCB)    04972 Pancreatic secretion     102952814 (PRKCB)    04973 Carbohydrate digestion and absorption     102952814 (PRKCB)   09155 Excretory system    04960 Aldosterone-regulated sodium reabsorption     102952814 (PRKCB)    04961 Endocrine and other factor-regulated calcium reabsorption     102952814 (PRKCB)   09156 Nervous system    04724 Glutamatergic synapse     102952814 (PRKCB)    04727 GABAergic synapse     102952814 (PRKCB)    04725 Cholinergic synapse     102952814 (PRKCB)    04728 Dopaminergic synapse     102952814 (PRKCB)    04726 Serotonergic synapse     102952814 (PRKCB)    04720 Long-term potentiation     102952814 (PRKCB)    04730 Long-term depression     102952814 (PRKCB)    04723 Retrograde endocannabinoid signaling     102952814 (PRKCB)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     102952814 (PRKCB)   09159 Environmental adaptation    04713 Circadian entrainment     102952814 (PRKCB)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     102952814 (PRKCB)    05206 MicroRNAs in cancer     102952814 (PRKCB)    05205 Proteoglycans in cancer     102952814 (PRKCB)    05207 Chemical carcinogenesis - receptor activation     102952814 (PRKCB)    05231 Choline metabolism in cancer     102952814 (PRKCB)   09162 Cancer: specific types    05225 Hepatocellular carcinoma     102952814 (PRKCB)    05214 Glioma     102952814 (PRKCB)    05223 Non-small cell lung cancer     102952814 (PRKCB)   09172 Infectious disease: viral    05170 Human immunodeficiency virus 1 infection     102952814 (PRKCB)    05161 Hepatitis B     102952814 (PRKCB)    05171 Coronavirus disease - COVID-19     102952814 (PRKCB)    05164 Influenza A     102952814 (PRKCB)    05163 Human cytomegalovirus infection     102952814 (PRKCB)   09174 Infectious disease: parasitic    05146 Amoebiasis     102952814 (PRKCB)    05140 Leishmaniasis     102952814 (PRKCB)    05143 African trypanosomiasis     102952814 (PRKCB)   09164 Neurodegenerative disease    05017 Spinocerebellar ataxia     102952814 (PRKCB)    05022 Pathways of neurodegeneration - multiple diseases     102952814 (PRKCB)   09165 Substance dependence    05031 Amphetamine addiction     102952814 (PRKCB)    05032 Morphine addiction     102952814 (PRKCB)   09166 Cardiovascular disease    05415 Diabetic cardiomyopathy     102952814 (PRKCB)   09167 Endocrine and metabolic disease    04931 Insulin resistance     102952814 (PRKCB)    04933 AGE-RAGE signaling pathway in diabetic complications     102952814 (PRKCB)   09176 Drug resistance: antineoplastic    01521 EGFR tyrosine kinase inhibitor resistance     102952814 (PRKCB)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:ptg01001]     102952814 (PRKCB) Enzymes [BR:ptg01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.11  Protein-serine/threonine kinases     2.7.11.13  protein kinase C      102952814 (PRKCB) Protein kinases [BR:ptg01001]  Serine/threonine kinases: AGC group   PKC family [OT]    102952814 (PRKCB) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Pkinase PK_Tyr_Ser-Thr C2 C1_1 Pkinase_C Kinase-like C1_2 ABC1 CEP76-C2 Haspin_kinase Motif Other DBs NCBI-GeneID:  102952814 NCBI-ProteinID:  XP_015393809 LinkDB All DBs Position Un AA seq 656 aa AA seqDB search MGSPFSLRSPLGNPTTAGSFSSSLWMWLYLFSFPEGTGASLGFGKQGFQCQVCCFVVHKR CHEFVTFSCPGADKGPASDDPRSKHKFKIHTYSSPTFCDHCGSLLYGLIHQGMKCDTCMM NVHKRCVMNVPSLCGTDHTERRGRIYIQAHIEREVLIVVVRDAKNLVPMDPNGLSDPYVK LKLIPDPKSESKQKTKTIKCSLNPEWNETFRFQLKESDKDRRLSVEIWDWDLTSRNDFMG SLSFGISELQKAGVDGWFKLLSQEEGEYFNVPVPPEGSEGNEELRQKFERAKIGQGTKAP EEKTTNTISKLDNNGNRDRMKLTDFNFLMVLGKGSFGKVMLSERKGTDELYAVKILKKDV VIQDDDVECTMVEKRVLALPGKPPFLTQLHSRFQTMDRLYFVMEYVNGGDLMYHIQQVGR FKEPHAVFYAAEIAIGLFFLQSKGIIYRDLKLDNVMLDSEGHIKIADFGMCKENIWDGVT TKTFCGTPDYIAPEIIAYQPYGKSVDWWAFGVLLYEMLAGQAPFEGEDEDELFQSIMEHN VAYPKSMSKEAVAICKGLMTKHPGKRLGCGPEGERDIKEHAFFRYIDWEKLERKEIQPPY KPKACGRNAENFDRFFTRHPPVLTPPDQEVIRNIDQSEFEGFSFVNSEFLKPEVKS NT seq 1971 nt NT seq  +upstreamnt  +downstreamnt atggggagccctttctctcttcgcagccccctggggaaccccaccaccgcggggtctttc tcatcctccctctggatgtggctttatctcttctctttccccgaaggtaccggggcatct ctgggtttcgggaagcaaggattccagtgccaagtctgctgtttcgtcgtgcacaagcgg tgccatgaatttgtcactttctcctgcccaggcgctgacaaaggtccagcctctgatgac ccccggagcaaacacaagtttaagatccacacatactccagccccacgttttgtgaccac tgcgggtcactgctgtatggactcatccaccaggggatgaaatgtgacacctgcatgatg aacgtgcacaagcgttgcgtgatgaacgtccccagcctgtgcggcacagaccacactgag cgccgaggccgcatctacatccaggctcacatcgagagggaagtcctcatcgtcgtcgta agagatgctaaaaaccttgtacctatggaccccaatggcttgtcagacccttatgtgaaa ctgaaactgattcctgaccccaagagcgagagcaagcagaagaccaaaaccatcaaatgc tccctcaaccccgagtggaatgagacattcagattccaactgaaagaatcggacaaagac agaaggctgtctgtagagatttgggattgggatctgaccagcaggaacgacttcatggga tctttgtcgtttgggatttccgaactgcagaaagctggtgttgatggctggtttaagctg ctgagccaggaggaaggcgagtacttcaatgtgcccgtgccgccagagggaagtgaaggg aatgaagaactacggcagaaattcgagagggccaagatcggtcaggggaccaaggctcca gaagaaaagacgaccaacaccatatccaaacttgacaacaatgggaacagagaccgaatg aaactgaccgattttaacttcctgatggtgctcgggaaaggaagctttggcaaggtcatg ctctcagagcggaaaggcacagacgagctctatgccgtgaagatcctgaagaaggacgtc gtgatccaagatgacgatgtggaatgcacgatggtggagaagcgggtgctggccctgccc gggaagccgccgttcctgacccagctccattcccgcttccagaccatggaccgcctgtac tttgtgatggagtacgtgaacgggggtgacctcatgtaccacatccaacaagttggccgg tttaaggagcctcacgctgtattttacgctgcagaaattgccatcggtctgttcttctta cagagcaagggcatcatttaccgtgacctcaaacttgacaatgtgatgctggattcagag ggccacatcaagattgctgattttggcatgtgtaaggaaaacatctgggatggggtgacc accaagacattctgtggcactccagactacatcgcccctgagataattgcttatcagccc tatgggaagtccgtggattggtgggcatttggagtcctgctgtatgaaatgttagctggc caggcaccctttgaaggggaggatgaggacgagctcttccagtccatcatggaacacaac gtggcttacccaaagtccatgtccaaggaagctgtggccatctgcaaagggctgatgacc aaacacccgggcaaacgtctgggatgtggacctgaaggtgaacgtgacatcaaagagcat gcatttttccggtatattgattgggagaaacttgaacgcaaagagatccagcccccgtat aagccaaaagcctgtgggcgaaatgctgaaaacttcgaccggtttttcacccgccatcca cccgtcctaacacctcccgaccaggaagtcatcaggaatattgaccaatcagaattcgaa ggattttcctttgttaactctgaatttttaaaacctgaagtcaagagctaa

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