Panthera tigris altaica (Amur tiger): 102953172
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Entry
102953172 CDS
T02988
Symbol
FPGS
Name
(RefSeq) folylpolyglutamate synthase
KO
K01930
folylpolyglutamate synthase [EC:
6.3.2.17
]
Organism
ptg
Panthera tigris altaica (Amur tiger)
Pathway
ptg00790
Folate biosynthesis
ptg01100
Metabolic pathways
ptg01240
Biosynthesis of cofactors
ptg01523
Antifolate resistance
ptg04981
Folate transport and metabolism
Brite
KEGG Orthology (KO) [BR:
ptg00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
102953172 (FPGS)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
102953172 (FPGS)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
102953172 (FPGS)
Enzymes [BR:
ptg01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.17 tetrahydrofolate synthase
102953172 (FPGS)
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Ortholog
Paralog
GFIT
Motif
Pfam:
Mur_ligase_M
Motif
Other DBs
NCBI-GeneID:
102953172
NCBI-ProteinID:
XP_007094609
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All DBs
Position
Un
AA seq
638 aa
AA seq
DB search
MWTSNPQDWAWKPPGIPGSNSSSSKTPAFCGSAPDSPHPPPPASSLGTSIAVDLIGGNER
KGARCPGLAIDALGFLCFRGPLVSLNLLPGDCGCQDAVRALNTLQTNAGYLEQVKRQRGD
PQAQLEAMKLYLARSGLQVEDLDQLNIIHVTGTKGKGSTCAFTERILRSYGLKTGFFSCP
HLVQVRERIRINGQPISPELFTKHFWPLYHRLEETKDSSSYASMPAYFRFLTLMAFHVFL
QEKVDLAVVEVGIGGAYDCTNIIRKPAVCGISSLGIDHTSILGDTVEEIAWQKGGIFKRG
VPAFTVLQPDGPLAVLRDRAQQISCPLYLSPPLEALEEGGPPLTLGLEGEHQRSNAALAL
QLARCWLQQKDYRGIGELKVSRPSLLRQMPLAPVFQPTTHMRHGLRDTEWLGRTQVLRRG
PLTWYLDGAHPASSMQACEGWGGARKEAWDVCISNLPPLPSPSGSEVLVLLFNSTGDRDP
AALLKLLQPCQFDYAVFCPNLTEVSTVGNADQQNFMVTLDQVLLRCLAHQQHWSRLAEEQ
AGPEPGEPTSSLLAPHPPEPRSASSLVFSCISHALLWISQGRDPVFQPPSPPQGLFAHPV
AGSGAGVLREAAAIHVLVTGSLHLVGGVLKLLEPALSQ
NT seq
1917 nt
NT seq
+upstream
nt +downstream
nt
atgtggacctccaatcctcaggattgggcatggaagcctccagggattcctggttctaat
tcctccagttctaagaccccagccttctgtggttctgctcctgactcccctcacccaccc
ccgcccgcctccagtttagggaccagtatagcagtggacctcattggagggaatgagcgc
aaaggcgcccgttgtcctggcttggccattgatgccctggggttcctctgtttccgtgga
cccctggttagtcttaacctgctgcctggggactgtggttgccaggatgctgtgcgcgcg
ctgaacaccctgcagaccaatgctggctatctggagcaggtaaagcgccagcggggtgac
cctcaggcacagctggaagccatgaagctgtacttggcacggagtgggctgcaggtggaa
gacttggaccagctgaacatcattcacgtcactgggaccaaggggaagggttccacttgt
gcctttactgaacgtattctccgaagctatggcctgaagacaggattcttcagctgcccc
cacctggtgcaggtgcgggagcggatccgcatcaacgggcagcccataagccctgagctc
ttcaccaagcacttctggcccctctaccaccggctggaggagaccaaggacagcagcagt
tatgcctccatgcccgcctacttccgcttcctcacgctcatggccttccacgtcttcctc
caagagaaggtggacctggcagtggtggaggtgggcattggtggcgcttacgactgcacc
aacatcatcaggaagcctgcggtgtgtggcatctcctctcttggcatcgaccacaccagc
attctgggggacacagtggaggagatcgcgtggcagaaagggggcatcttcaagcgtggc
gtccccgccttcaccgtgctccagcctgacggtcccctggcagtgctgagggaccgggcc
cagcagatctcgtgtcctctctacctgtccccacccctggaagccctggaggaagggggg
ccgccgctgaccctgggcctggagggagagcaccagaggtccaatgccgccttggccttg
cagctggctcgctgctggctacagcaaaaggactaccggggcatcggggagctgaaggtg
tccaggcccagtctcttgcggcagatgcccctggcgcccgtgttccagcccacgacccac
atgcggcatgggcttcgggacacggagtggctgggccggacgcaggtgctgcggcgcggg
cccctcacctggtacctggatggcgcgcaccccgccagcagcatgcaggcctgcgaagga
tggggtggggcccgcaaagaagcctgggatgtatgcatctccaacctgcctcctctcccc
tctcccagcggctctgaggtgcttgtcctgcttttcaactccaccggagaccgggatcct
gcagcactgctgaagctgctgcagccctgtcagtttgactatgctgttttctgccctaac
ctgacagaggtttcaactgttggcaatgcagaccagcagaacttcatggtgaccctggac
caggtgttgctccgctgccttgcacaccaacagcactggagccgcctggccgaggagcag
gccggcccggagcctggtgagcccacatcctcgctgctggctccccacccgcccgagccc
cgtagcgccagctccctcgtcttcagctgcatctcccacgccttgctgtggatcagtcaa
ggccgggaccctgtctttcagccacccagtcccccgcagggcctcttcgcccaccctgtg
gcaggcagcggggccggcgtgctccgtgaggctgccgccatccacgtgctggtcaccggc
agcctgcacctggtgggcggcgtcctgaagctgctggagccggccctgtcccagtag
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