Panthera tigris altaica (Amur tiger): 102953204 Help Entry 102953204         CDS       T02988                                  Symbol TYK2 Name (RefSeq) tyrosine kinase 2   KO K11219   non-receptor tyrosine-protein kinase TYK2 [EC:2.7.10.2] Organism ptg  Panthera tigris altaica (Amur tiger) Pathway ptg04217   Necroptosis ptg04380   Osteoclast differentiation ptg04620   Toll-like receptor signaling pathway ptg04621   NOD-like receptor signaling pathway ptg04630   JAK-STAT signaling pathway ptg04658   Th1 and Th2 cell differentiation ptg04659   Th17 cell differentiation ptg05145   Toxoplasmosis ptg05160   Hepatitis C ptg05161   Hepatitis B ptg05162   Measles ptg05164   Influenza A ptg05165   Human papillomavirus infection ptg05167   Kaposi sarcoma-associated herpesvirus infection ptg05168   Herpes simplex virus 1 infection ptg05169   Epstein-Barr virus infection ptg05171   Coronavirus disease - COVID-19 Brite KEGG Orthology (KO) [BR:ptg00001]  09130 Environmental Information Processing   09132 Signal transduction    04630 JAK-STAT signaling pathway     102953204 (TYK2)  09140 Cellular Processes   09143 Cell growth and death    04217 Necroptosis     102953204 (TYK2)  09150 Organismal Systems   09151 Immune system    04620 Toll-like receptor signaling pathway     102953204 (TYK2)    04621 NOD-like receptor signaling pathway     102953204 (TYK2)    04658 Th1 and Th2 cell differentiation     102953204 (TYK2)    04659 Th17 cell differentiation     102953204 (TYK2)   09158 Development and regeneration    04380 Osteoclast differentiation     102953204 (TYK2)  09160 Human Diseases   09172 Infectious disease: viral    05161 Hepatitis B     102953204 (TYK2)    05160 Hepatitis C     102953204 (TYK2)    05171 Coronavirus disease - COVID-19     102953204 (TYK2)    05164 Influenza A     102953204 (TYK2)    05162 Measles     102953204 (TYK2)    05168 Herpes simplex virus 1 infection     102953204 (TYK2)    05167 Kaposi sarcoma-associated herpesvirus infection     102953204 (TYK2)    05169 Epstein-Barr virus infection     102953204 (TYK2)    05165 Human papillomavirus infection     102953204 (TYK2)   09174 Infectious disease: parasitic    05145 Toxoplasmosis     102953204 (TYK2)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:ptg01001]     102953204 (TYK2) Enzymes [BR:ptg01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.10  Protein-tyrosine kinases     2.7.10.2  non-specific protein-tyrosine kinase      102953204 (TYK2) Protein kinases [BR:ptg01001]  Non-receptor tyrosine kinases   JAK family [OT]    102953204 (TYK2) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  PK_Tyr_Ser-Thr Pkinase Jak1_Phl FERM_F2 FERM_F1 SH2_1 Kinase-like Kdo FERM_C_FAK1 RIO1 ABC1 RA_2 Motif Other DBs NCBI-GeneID:  102953204 NCBI-ProteinID:  XP_015391775 LinkDB All DBs Position Un AA seq 1150 aa AA seqDB search MPLCRWGATTRDSRPDGDEAQPMVSRGGLKVLLHWAGPDGGDPWVTFSEATLTAEEVCIH IAHKVGITPSCLNLFALFDAQAQVWLPPNHILEVSRDMNLTLYFRMRFYFRNWHSMNPQE PAVYRCGPTRAKSSSEQAEQGVQLLDPASFEYLFEQGKHEFVNDVAPLWELSSEEEIHHF KNESLGMAFLHLCHLALCHGIPLEKVAKKISFKDCIPRSFRLQLRRHNALTRLRLRRLFR RFVRAFQPGTLVWYLGARGLGSPSLPPXGSVFWRVCLLGEGLRPICDTGTXGDAXGACPR ENCAGDXAGTALLGFQGPSGDGCSRNPRAGPSGKKSKAQEVGNQPVDRPQEAPWAYFCDF QDITHVVLKERHVSIHCQDKCLELTLPSRAVALSLVSLVDGYFRLTADSSHYLCREVAPP RLVMSIRDGIHGPLLPGLGALPAWTPAHRPHPCHLPQAPGGQQLHLRKFPIELRAGSFEL EGWDRSFPSVRELRTALQGCSLRVGDDCFSLRRCCLPRPGELSNLIIMRGSRASPGPLNL SQLSFHRVCQDDISQLSHLGQGTRTNVYEGILRVGERGPKEGTADGGDPPTPSGDRGQEL RVVLKVLDPSHHDIALAFYETASLMSQVSHVHLAFVHGVCVHGSENIMVTEYVEHGPLDV WLRRERGHVPVAWKVAVAQQLASALSYLEDKSLVHGNVCGRNILLARLGLAEGTSPFIKL SDPGVGLGALSREERVERIPWTAPECLSGGASTLTTAADKWGFGVTLLEICFDGEAPLQG RGPSEKECFYQKQHQLPQPSCPELATLTSQCLTYEPAQRPSFRTILRDLTQLQPQNLADI LAVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKAGGG PQLRTGWRREIDILRTLYHKHIVKYKGCCEDQGEKSVQLVMEYVPLGSLRDYLPRHNVGL AQLLLFAQQICEGMAYLHAQHYVHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRV REDGDSPVFWYAPECLKECKFYYASDVWSFGVTMYELLTYCDSSQSPPSKFIELIGLTQG QMTVLRLTELLERGERLPRPEKCPCEIYLLMKNCWEAEASFRPTFQNLIPILKTVQEKYQ GQAASVFNVC NT seq 3453 nt NT seq  +upstreamnt  +downstreamnt atgcctctgtgccgttggggtgccaccaccagggacagcaggcctgatggggatgaggct cagcccatggtctccaggggaggcctaaaggtccttctgcactgggctggccctgatggc ggggacccctgggtcaccttcagcgaggccacactgaccgcagaggaggtctgcatccac atcgcacacaaagtcggcatcactccatcctgcctcaatctcttcgccctctttgatgcc caggcccaggtgtggctgcccccaaaccacatcttggaggtctccagagacatgaacctg acattgtacttccgcatgaggttttatttccggaattggcacagcatgaatcctcaggag ccggccgtgtaccgctgtgggcccaccagggccaagtcttcctcggaacaggcagagcag ggcgtgcaactcctggacccagcctcctttgagtacctctttgagcagggcaagcacgag tttgtgaatgatgtggcaccactgtgggagctgtcgagcgaggaggagatccaccatttt aagaacgagagcctgggcatggcctttctgcacctctgccacctcgccctttgccatggt atccccctggagaaggtggccaagaagatcagcttcaaggactgcatcccgcgctccttc cggctgcagctccggcggcacaacgcgttaacacggctgcgcctacggagactcttccgc aggtttgtgcgggccttccagccggggaccctcgtctggtacctgggggcgagagggctc ggctccccctctcttcctccctgaggttctgtcttctggcgtgtgtgtctcttgggggaa ggtctccgtcccatctgtgacacggggacttagggggatgcctgaggagcctgtccccgg gaaaactgtgcgggggactaagctggcacggccctgctgggtttccagggtcccagtggc gatggttgcagcaggaacccccgtgctggcccatcagggaagaaaagcaaggcccaggag gtgggcaaccagccagtggacaggcctcaggaagcgccgtgggcctacttctgtgacttc caggacatcacccacgtggtgctgaaagagcgccacgtcagcatccactgtcaggacaag tgcctggagctcaccctgccttcccgggctgtggccctatccttggtgtcgctggtggac ggctatttccgcctgacggccgactcgagccactacctgtgccgggaggtggcccctccg cggctggtgatgagcatccgggatggcatccacgggcccttgctgccggggctgggcgcg ctccctgcctggacccctgctcaccgcccccacccctgccacctaccccaggcacctggc gggcagcagctgcacctccgtaaattccccattgagctgcgggccgggagcttcgagctg gagggctgggaccgctccttcccgagcgtgcgggagctgcgcaccgccctgcagggctgc tcgctgcgggtcggggacgactgtttctccctgcgccgctgctgcctgccacggcccgga gagctctccaacctcatcatcatgcgtgggtctcgggccagccctgggccactcaacctc agccagctcagcttccaccgcgtctgccaggatgacattagtcagctgtctcacttgggc caaggcacgaggaccaatgtgtatgagggcatcttacgggtgggggaaagaggccccaag gagggcacggcagatggtggggacccccccacgcccagtggggaccgtggccaggagcta cgagtggtactcaaggtgctggatcccagtcaccacgacatcgccctggccttctacgag acagccagcctcatgagccaggtctcccacgtgcacctggcctttgtgcacggcgtctgc gtgcacggctctgagaacatcatggtgacagagtacgtggagcacggacccctggatgtg tggctgcggcgggagaggggccacgtgcctgtggcctggaaggtggcagtggcccagcag ctggccagcgctctcagctacctggaagacaagagcctggttcatggtaatgtgtgtggc cggaacatcctgctggcacggctgggactggcggagggcaccagcccctttatcaagctg agcgatcccggtgtgggcctgggtgccctttccagggaggagcgggtagagaggatcccc tggacagcccccgagtgcctgtcaggtggggccagcaccctaaccactgcagctgacaaa tggggctttggtgtcaccctcctggagatctgcttcgacggggaggcccctctgcagggc cgcggcccttccgagaaagagtgcttctaccagaagcagcaccagcttcctcagccctca tgcccggagctggccacactcaccagccagtgcctgacctatgaaccagctcagcggccc tccttccgcaccatcctgcgtgacctcactcagctgcagccccagaatcttgctgacatc ttggctgtgaaccccgactcgcctgcgtcagaccccaccgttttccacaagcgctatttg aaaaagatccgggatctgggcgagggtcatttcggcaaggtcagtctgtattgctacgac ccgactaacgacggcaccggcgagatggtggctgtgaaggccctcaaggcgggcgggggc ccccagctccgcactggctggcggcgggagatcgacatcctgcgcacgctctaccacaag cacatcgtcaaatacaagggatgctgcgaggaccaaggagagaagtcggtgcagctcgtt atggagtacgtgcctctgggcagcctccgggactaccttccccggcacaacgtcggactg gcccaactgctactcttcgcccagcagatctgtgagggcatggcctaccttcatgcacag cactacgtccaccgagacctggctgcccgcaacgtgctgctggacaacgacaggctggtc aaaatcggggactttggcctagccaaggctgtgcctgaaggccatgagtactaccgcgtg cgcgaagatggggacagccccgtattctggtatgctccagagtgcctgaaggagtgtaag ttctactatgcatccgacgtctggtccttcggggtcaccatgtatgagctgctgacctac tgtgactccagccagagccccccttcgaaattcatcgagctcataggcctcacccaaggg cagatgacggtgctgaggctcactgagctgctggaacgaggggagaggctgccgcggcca gagaaatgcccttgcgagatctacctcctcatgaagaactgctgggaggcagaggcctca ttccgccccactttccagaacctcatccccattctcaagacggtccaggagaaataccaa ggccaggccgcctcagtgttcaatgtgtgctga

DBGET integrated database retrieval system