Panthera tigris altaica (Amur tiger): 102953749
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Entry
102953749 CDS
T02988
Symbol
HSPA5
Name
(RefSeq) heat shock protein family A (Hsp70) member 5
KO
K09490
endoplasmic reticulum chaperone BiP [EC:
3.6.4.10
]
Organism
ptg
Panthera tigris altaica (Amur tiger)
Pathway
ptg03060
Protein export
ptg04141
Protein processing in endoplasmic reticulum
ptg04612
Antigen processing and presentation
ptg04918
Thyroid hormone synthesis
ptg05012
Parkinson disease
ptg05014
Amyotrophic lateral sclerosis
ptg05020
Prion disease
ptg05022
Pathways of neurodegeneration - multiple diseases
ptg05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
ptg00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
03060 Protein export
102953749 (HSPA5)
04141 Protein processing in endoplasmic reticulum
102953749 (HSPA5)
09150 Organismal Systems
09151 Immune system
04612 Antigen processing and presentation
102953749 (HSPA5)
09152 Endocrine system
04918 Thyroid hormone synthesis
102953749 (HSPA5)
09160 Human Diseases
09164 Neurodegenerative disease
05012 Parkinson disease
102953749 (HSPA5)
05014 Amyotrophic lateral sclerosis
102953749 (HSPA5)
05020 Prion disease
102953749 (HSPA5)
05022 Pathways of neurodegeneration - multiple diseases
102953749 (HSPA5)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
102953749 (HSPA5)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03110 Chaperones and folding catalysts [BR:
ptg03110
]
102953749 (HSPA5)
04131 Membrane trafficking [BR:
ptg04131
]
102953749 (HSPA5)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
ptg04147
]
102953749 (HSPA5)
Enzymes [BR:
ptg01000
]
3. Hydrolases
3.6 Acting on acid anhydrides
3.6.4 Acting on acid anhydrides to facilitate cellular and subcellular movement
3.6.4.10 non-chaperonin molecular chaperone ATPase
102953749 (HSPA5)
Chaperones and folding catalysts [BR:
ptg03110
]
Heat shock proteins
HSP70 / DNAK
102953749 (HSPA5)
Membrane trafficking [BR:
ptg04131
]
Endoplasmic reticulum (ER) - Golgi transport
Forward pathways
ER-Golgi intermediate compartment (ERGIC) proteins
102953749 (HSPA5)
Autophagy
ER-phagy
ER stress-related proteins
102953749 (HSPA5)
Exosome [BR:
ptg04147
]
Exosomal proteins
Exosomal proteins of haemopoietic cells (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
102953749 (HSPA5)
Exosomal proteins of other body fluids (saliva and urine)
102953749 (HSPA5)
Exosomal proteins of colorectal cancer cells
102953749 (HSPA5)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
HSP70
MreB_Mbl
Hydantoinase_A
FtsA
DDR
FGGY_C
ParM_N
Motif
Other DBs
NCBI-GeneID:
102953749
NCBI-ProteinID:
XP_007094457
UniProt:
A0A8C9M4U4
LinkDB
All DBs
Position
Un
AA seq
654 aa
AA seq
DB search
MKLSLVAAVLLLLGAARAEEEDKKEDVGTVVGIDLGTTYSCVGVFKNGRVEIIANDQGNR
ITPSYVAFTPEGERLIGDAAKNQLTSNPENTVFDAKRLIGRTWNDPSVQQDIKFLPFKVV
EKKTKPYIQVDIGGGQTKTFAPEEISAMVLTKMKETAEAYLGKKVTHAVVTVPAYFNDAQ
RQATKDAGTIAGLNVMRIINEPTAAAIAYGLDKREGEKNILVFDLGGGTFDVSLLTIDNG
VFEVVATNGDTHLGGEDFDQRVMEHFIKLYKKKTGKDVRKDNRAVQKLRREVEKAKRALS
SQHQARIEIESFYEGEDFSETLTRAKFEELNMDLFRSTMKPVQKVLEDSDLKKSDIDEIV
LVGGSTRIPKIQQLVKEFFNGKEPSRGINPDEAVAYGAAVQAGVLSGDQDTGDLVLLDVC
PLTLGIETVGGVMTKLIPRNTVVPTKKSQIFSTASDNQPTVTIKVYEGERPLTKDNHLLG
TFDLTGIPPAPRGVPQIEVTFEIDVNGILRVTAEDKGTGNKNKITITNDQNRLTPEEIER
MVNDAEKFAEEDKKLKERIDTRNELESYAYSLKNQIGDKEKLGGKLSSEDKETMEKAVEE
KIEWLESHQDADIEDFKAKKKELEEIVQPIISKLYGSAGPPPTGDEEPADKDEL
NT seq
1965 nt
NT seq
+upstream
nt +downstream
nt
atgaagctgtccctggtggctgcggtgctgctgttgctcggcgcggcgcgggccgaggag
gaggacaagaaggaagacgtgggcacggtggtcggcatcgacctggggaccacctactcc
tgcgtcggggtgttcaagaacggccgcgtggagatcatcgccaacgatcagggcaatcgc
atcacgccgtcttatgtggccttcactcctgaaggggagcgtctgatcggcgatgcagcc
aagaaccagctcacctccaaccctgagaacacggtcttcgacgccaagaggctcatcggc
cgcacatggaacgacccatctgtgcagcaggacatcaagttcttgcctttcaaggtggtt
gaaaagaaaactaaaccatatattcaagttgatattggaggtgggcagacaaagacattt
gctcctgaagaaatttctgccatggttctcactaaaatgaaggaaactgctgaggcttat
ttgggaaagaaggttacccatgcagttgttactgtaccagcctatttcaatgatgcccaa
cgccaggcaaccaaagatgctggaactattgctggattgaatgttatgagaatcatcaat
gagcctacagcagctgctattgcttatggcttggataaaagggaaggggaaaagaacatc
ctggtgtttgacctcggtggtggaacttttgatgtgtcgctcctcaccattgataatggt
gtcttcgaagttgtggctactaatggagacactcatctgggtggagaagactttgaccaa
cgtgtcatggaacacttcatcaagctctacaaaaagaagacaggcaaagatgtcaggaaa
gacaacagagctgtgcagaaactccgacgtgaggtagaaaaggccaaacgggccctgtct
tctcaacatcaagcaagaattgaaattgagtctttctatgaaggagaagacttctctgaa
actctgaccagggccaaatttgaagagctaaacatggacctgttccgttctaccatgaag
cctgtccagaaggtgctggaggattctgacttaaagaagtctgatattgatgaaattgtt
cttgttggtggctctactcgaatcccgaagattcaacaactggttaaagaatttttcaat
ggcaaggagccatcccgtggcataaacccagatgaggccgtagcatatggtgctgctgtc
caggctggggtactctctggtgatcaagatacaggtgatctggtactgcttgatgtatgt
ccccttacacttggtattgaaactgtgggaggtgtcatgaccaaactgattccaaggaac
actgtggtgcccaccaagaagtctcagatcttttctacagcttccgataatcaacccact
gttacaatcaaggtctatgaaggtgaacgacccctgaccaaagacaatcatcttctggga
acttttgatctgactggaattcctcctgctccccgtggggtcccacagattgaagtcacc
tttgaaatcgatgtgaatggcattcttagagtgacagctgaagacaaaggtacaggcaac
aaaaataagatcaccattaccaatgaccaaaatcgcctgacacctgaagaaattgaaagg
atggttaatgatgctgagaagtttgccgaggaagacaaaaagctcaaggagcgcattgat
actagaaatgaattggaaagctatgcctactctttaaagaatcaaattggagataaagaa
aagctgggaggtaaactctcctctgaagacaaggaaaccatggaaaaagccgtagaggaa
aagattgaatggctagaaagtcaccaagatgctgacattgaagatttcaaagctaaaaag
aaggaactagaagaaattgttcagccaattatcagcaaactctatggaagtgcaggccct
cccccaactggtgatgaggaaccagcagataaagatgagttgtag
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