Panthera tigris altaica (Amur tiger): 102955481
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Entry
102955481 CDS
T02988
Symbol
PDGFRA
Name
(RefSeq) platelet derived growth factor receptor alpha
KO
K04363
platelet-derived growth factor receptor alpha [EC:
2.7.10.1
]
Organism
ptg
Panthera tigris altaica (Amur tiger)
Pathway
ptg01521
EGFR tyrosine kinase inhibitor resistance
ptg04010
MAPK signaling pathway
ptg04014
Ras signaling pathway
ptg04015
Rap1 signaling pathway
ptg04020
Calcium signaling pathway
ptg04072
Phospholipase D signaling pathway
ptg04144
Endocytosis
ptg04151
PI3K-Akt signaling pathway
ptg04510
Focal adhesion
ptg04540
Gap junction
ptg04630
JAK-STAT signaling pathway
ptg04810
Regulation of actin cytoskeleton
ptg05163
Human cytomegalovirus infection
ptg05200
Pathways in cancer
ptg05206
MicroRNAs in cancer
ptg05214
Glioma
ptg05215
Prostate cancer
ptg05218
Melanoma
ptg05230
Central carbon metabolism in cancer
ptg05231
Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
ptg00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
102955481 (PDGFRA)
04014 Ras signaling pathway
102955481 (PDGFRA)
04015 Rap1 signaling pathway
102955481 (PDGFRA)
04630 JAK-STAT signaling pathway
102955481 (PDGFRA)
04020 Calcium signaling pathway
102955481 (PDGFRA)
04072 Phospholipase D signaling pathway
102955481 (PDGFRA)
04151 PI3K-Akt signaling pathway
102955481 (PDGFRA)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
102955481 (PDGFRA)
09144 Cellular community - eukaryotes
04510 Focal adhesion
102955481 (PDGFRA)
04540 Gap junction
102955481 (PDGFRA)
09142 Cell motility
04810 Regulation of actin cytoskeleton
102955481 (PDGFRA)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
102955481 (PDGFRA)
05206 MicroRNAs in cancer
102955481 (PDGFRA)
05230 Central carbon metabolism in cancer
102955481 (PDGFRA)
05231 Choline metabolism in cancer
102955481 (PDGFRA)
09162 Cancer: specific types
05214 Glioma
102955481 (PDGFRA)
05218 Melanoma
102955481 (PDGFRA)
05215 Prostate cancer
102955481 (PDGFRA)
09172 Infectious disease: viral
05163 Human cytomegalovirus infection
102955481 (PDGFRA)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
102955481 (PDGFRA)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
ptg01001
]
102955481 (PDGFRA)
09183 Protein families: signaling and cellular processes
04090 CD molecules [BR:
ptg04090
]
102955481 (PDGFRA)
Enzymes [BR:
ptg01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
102955481 (PDGFRA)
Protein kinases [BR:
ptg01001
]
Receptor tyrosine kinases (RTK)
PDGFR family [OT]
102955481 (PDGFRA)
CD molecules [BR:
ptg04090
]
Proteins
102955481 (PDGFRA)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
Ig_3
I-set
ig
Ig_2
VEGFR1-3_N_Ig-like
V-set
VEGFR-1-like_Ig-like
Herpes_gE
Motif
Other DBs
NCBI-GeneID:
102955481
NCBI-ProteinID:
XP_007075943
UniProt:
A0A8C9MCE3
LinkDB
All DBs
Position
Un
AA seq
1089 aa
AA seq
DB search
MGTSHLALLVLVCLLTGPSLISCQLSLPSILPNENEKVVQLNSSFSLQCFGESEVSWQYP
MSEEENPNVEVRNEENNSGLFVTVLEVVNASAAHTGLYTCYYNHTQTDENEIEGRRIYIY
VPDPDVAFVPLGMTDYLVIVEDDDSAIIPCRTTDPKTPVTLRSSDGVVHASYDSRQGFNG
TFSVGPYICEATVSGKKFQTIPFNVYALKATSELDLEMEALKTVYKSGETIVVTCAVFNN
EVVDLQWTYPGEVKGKGITMLEEIKVPSIKLVYTLTVPEATVKDSGDYECAARQATKEVK
EMKKVTISVHEKGFIEIKPNFSPLEAVDLHEVKHFVVDVQAYPPPRISWLKDNLTLIENL
TEITTDIEKIQEIRYRSKLKLIRAKEEDSGHYTIVVQNEDDVKSYTFELLTQVPSSILDL
VDDHHGSTGGQTVRCTAEGTPLPDIEWMICKDIKKCNNETSWTVLANNISNIITEVHRRD
RSTVEGRVTFTRVEETIAVRCLAKNLLGAENRELKLVAPTLRSELTVAAAVLVLLVIVII
SLIVLVVIWKQKPRYEIRWRVIESISPDGHEYIYVDPMQLPYDSRWEFPRDGLVLGRILG
SGAFGKVVEGTAYGLSRSQPVMKVAVKMLKPTARSSEKQALMSELKIMTHLGPHLNIVNL
LGACTKSGPIYIITEYCFYGDLVNYLHKNRDSFLSRHPEKPKKELDIFGLNPADESTRSY
VILSFENNGDYMDMKQADTTQYVPMLERKEVSKYSDIQRSLYDRPASYKKKSTSDSEVKN
LLSDDNSEGLTLLDLLSFTYQVARGMEFLASKNCVHRDLAARNVLLAQGKIVKICDFGLA
RDIMHDSNYVSKGSTFLPVKWMAPESIFDNLYTTLSDVWSYGILLWEIFSLGGTPYPGMM
VDSTFYNKIKNGYRMAKPDHATSEVYEIMVKCWHSEPEKRPSFYHLSEIVENLLPGQYKK
SYEKIHLDFLKSDHPAVARMRVDSDNAYIGVTYKHEEDKLKDWEGSLDEQRLSADSGYII
PLPDIDPVPEEEDLGKRNRHSSQTSEESAIETGSSSSTFVKREDETIEDIDMMDDIGIDS
SDLVEDSFL
NT seq
3270 nt
NT seq
+upstream
nt +downstream
nt
atggggacttcccacctggcgctcctggtgttagtctgtctcctcacaggaccgagccta
atctcctgccagctttcattaccctctatccttccaaacgaaaatgaaaaggtcgtgcag
ctgaattcctccttttctctgcaatgctttggggagagtgaagtgagctggcagtacccc
atgtctgaagaagagaaccccaatgtggaagtcagaaatgaagaaaacaacagtggcctt
tttgtgacggtgctggaagtggtcaatgcgtcggcggcccacacgggactgtacacttgc
tattacaaccacactcagacggacgaaaacgagatcgaaggcaggcgcatttacatctat
gtcccagacccagacgtagccttcgtacctctaggaatgacagattatttagttatcgtg
gaggacgatgactctgccatcataccttgtcgcacaactgatcccaagactccggttacc
ttacgcagcagtgacggggtggttcacgcctcctatgacagcagacagggctttaatggg
accttcagcgtcgggccctatatctgcgaagccacagtcagcgggaagaagttccagacc
atcccatttaatgtttatgctttaaaagcaacatcagaacttgatctagaaatggaagct
ctcaaaactgtgtataagtccggggagacgattgtggtcacctgcgccgtctttaacaac
gaggtggttgaccttcagtggacttaccctggagaagtgaaaggcaaaggcatcacgatg
ctggaggagatcaaggtcccgtccatcaaactggtttacacgctgacggtccccgaggcc
acggtgaaggatagtggagattatgaatgtgctgcccgccaggccaccaaggaggtcaaa
gagatgaagaaagtcaccatttccgtccatgagaaagggttcattgaaatcaaacccaac
ttcagcccgttggaggctgttgacctgcatgaagtcaaacatttcgtggtggacgtgcag
gcctacccccctcccaggatatcctggctgaaggacaacctgactctgattgaaaatctc
acggagatcaccactgacatagaaaagattcaggaaataaggtatcgaagcaaattaaag
ctgatccgtgcgaaggaagaagacagcggccattacactattgtcgtccaaaatgaagac
gacgtgaagagctatactttcgaactcttaacgcaagttccctcgtctattctggacttg
gtcgacgaccaccatggctccaccgggggacagaccgtgagatgcacagcagaagggaca
cctcttcccgatatcgagtggatgatttgcaaggatattaagaaatgtaataacgaaact
tcatggacggttttggcaaacaacatctcgaacatcatcacggaggtccaccgccgggac
aggagtactgtggagggccgagtgacgttcaccagagtggaggagaccatcgccgttcga
tgcctggccaagaatcttcttggagccgagaaccgagagctgaagctggtggctcccacg
ctgcgttctgaactcacagtggcagctgcagtcctggtcctgctggtgattgtgatcatc
tccctcattgtcctggttgtcatttggaaacagaaaccgaggtatgaaattcgttggagg
gtcattgaatcgatcagccccgatggacatgaatatatttatgtggacccgatgcagctg
ccttatgactctagatgggagtttccaagagatggactagtgcttggtcgtatcctggga
tctggtgcattcgggaaagtggtcgaaggaactgcctatggattgagccggtcccagcct
gtcatgaaagtagcagtaaagatgctaaaacccacagccagatccagtgaaaaacaagct
ctcatgtcggaactgaagataatgactcatctggggccccatttaaacattgtgaacttg
ctgggggcctgcaccaagtcaggccctatttacatcatcacggagtactgcttctatggg
gatttggtcaactatttgcataagaatagggacagcttcctgagccgacacccagagaag
ccaaagaaagagttggacatttttgggctgaaccctgctgatgaaagcacacggagttac
gttattttatcttttgaaaacaatggtgactatatggacatgaagcaagctgataccaca
cagtacgtccccatgctggaaagaaaagaggtttctaaatactcggacatccagagatcg
ctgtatgatcgcccggcctcgtataagaagaaatctacgtcagactcggaagtcaaaaac
ctcctttcagacgataactcagaaggcctgactctgctggatttgttgagctttacctat
caagtggcgcgagggatggaatttttggcttccaaaaattgtgtccaccgggacctggct
gctcgcaacgtcctcctggcgcaaggcaaaatcgtgaagatctgtgacttcggcctggcc
agggacatcatgcacgattcaaactacgtgtccaaaggcagcacctttctccccgtgaag
tggatggctcctgagagcatcttcgacaacctctacaccacgctgagtgacgtctggtct
tacggcattctgctctgggagatcttttcccttgggggcaccccgtaccctggtatgatg
gtggattccactttctacaacaagatcaagaacgggtaccggatggccaagcctgaccac
gccaccagcgaagtctatgaaatcatggtcaagtgctggcacagtgagccggagaagaga
ccctccttttaccacctgagtgagattgtggagaatctgttgccgggacaatataagaag
agctacgaaaagattcacctggacttcttgaagagcgaccaccctgccgtggcgcgcatg
cgcgtggactcggacaacgcctacatcggcgtcacctacaaacacgaggaagacaagctg
aaggactgggaaggcagcctggacgagcagaggctgagtgcagacagcggctacatcatc
cctctgcccgacatcgaccctgttcctgaggaggaggacctgggcaagaggaacagacac
agctcgcagacctcagaagagagcgccattgagacaggttccagcagctctaccttcgtc
aagagagaggatgaaaccatcgaggacatcgacatgatggatgacattggcatagactcc
tcagacctggtagaggacagcttcctgtga
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integrated database retrieval system
