Panthera tigris altaica (Amur tiger): 102955540
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Entry
102955540 CDS
T02988
Symbol
ERN1
Name
(RefSeq) endoplasmic reticulum to nucleus signaling 1
KO
K08852
serine/threonine-protein kinase/endoribonuclease IRE1 [EC:
2.7.11.1
3.1.26.-]
Organism
ptg
Panthera tigris altaica (Amur tiger)
Pathway
ptg04140
Autophagy - animal
ptg04141
Protein processing in endoplasmic reticulum
ptg04210
Apoptosis
ptg04932
Non-alcoholic fatty liver disease
ptg05010
Alzheimer disease
ptg05012
Parkinson disease
ptg05014
Amyotrophic lateral sclerosis
ptg05016
Huntington disease
ptg05017
Spinocerebellar ataxia
ptg05022
Pathways of neurodegeneration - multiple diseases
ptg05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
ptg00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04141 Protein processing in endoplasmic reticulum
102955540 (ERN1)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
102955540 (ERN1)
09143 Cell growth and death
04210 Apoptosis
102955540 (ERN1)
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
102955540 (ERN1)
05012 Parkinson disease
102955540 (ERN1)
05014 Amyotrophic lateral sclerosis
102955540 (ERN1)
05016 Huntington disease
102955540 (ERN1)
05017 Spinocerebellar ataxia
102955540 (ERN1)
05022 Pathways of neurodegeneration - multiple diseases
102955540 (ERN1)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
102955540 (ERN1)
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
102955540 (ERN1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
ptg01001
]
102955540 (ERN1)
Enzymes [BR:
ptg01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
102955540 (ERN1)
Protein kinases [BR:
ptg01001
]
Serine/threonine kinases: Other
IRE family
102955540 (ERN1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Pkinase
Ribonuc_2-5A
PK_Tyr_Ser-Thr
PQQ_2
PQQ
Pkinase_fungal
Kdo
APH
Motif
Other DBs
NCBI-GeneID:
102955540
NCBI-ProteinID:
XP_007088337
LinkDB
All DBs
Position
Un
AA seq
973 aa
AA seq
DB search
MCLGCGLSNLSVFICEIFGSPSTVTLPETLLFVSTLDGSLHAVSKRTGSIKWTLKEDPVL
QVPTHVEEPAFLPDPNDGSLYTLGGKNNEGLTKLPFPIPELVQASPCRSSDGILYMGKKQ
DIWYVIDLLTGEKQQTLSSAFADSLCPSTSLLYLGRTEYTITMYDTKTRELRWNATYFDY
AASLPEDDGDYKMSHFVSNGDGLVVTVDSESGDVLWIQNYASPVVAFYVWQREGLRKVMH
INVAVETLRYLTFMSGEVGRITKWKYPFPKETEAKSKLTPTLYVGKYSTSLYASPSMVHE
GVAVVPRGSTLPLLEGPQTDGVTIGDKGECVITPSTDLKFDPGLKGKSKLNYLRNYWLLI
GHHETPLSASTKMLERFPNNLPKHRENVIPADSEKKSFEEVINLVEQTSENAPTAVSQEV
EEKFEHAPAKPEAPVDSVLKDIATIILSTFLLIGWVAFIITYPLSMHQQQQLQHQQFQKE
LEKIQLLQQQQLPFHPPGDVAQDAELLDSSGLYSESSGTSSPSTSPRASNHSLHSSGSAS
RAGASPFLEQDDEDEETSMVIVGKISFCPKDVLGHGAEGTIVYRGMFDNRDVAVKRILPE
CFSFADREVQLLRESDEHPNVIRYFCTERDRQFQYIAIELCAATLQEYVEQKDFAHLGLE
PITLLQQTTSGLAHLHSLNIVHRDLKPHNILLSMPNAHGRIKAMISDFGLCKKLAVGRHS
FSRRSGVPGTEGWIAPEMLSEDCKDNPTYTVDIFSAGCVFYYVISEGSHPFGKSLQRQAN
ILLGAYSLDCLHPEKHEDVIARELIEKMIAMDPQKRPSAKHVLKHPFFWSLEKQLQFFQD
VSDRIEKESLDGPIVKQLERGGRAVVKTDWRENITVPLQTDLRKFRTYKGGSVRDLLRAM
RNKKHHYRELPAEVRETLGSLPDDFVRYFTSRFPHLLPHTYRAMEPCSHERLFQPYYCHE
PPELRPPVTPDAL
NT seq
2922 nt
NT seq
+upstream
nt +downstream
nt
atgtgccttggatgcgggctctctaacctcagcgtcttcatctgtgagatttttggaagt
cccagcacagtgacacttcccgaaaccttgttgtttgtgtcaaccctggatggaagcttg
catgctgtcagtaagaggacgggctcaatcaaatggactttaaaagaagatccggttctg
caggttccaacgcatgtggaagagcctgccttcctcccagatcccaatgatggcagcctg
tatacacttgggggcaagaataatgaaggcctgacgaaacttcccttccccatcccagag
ctcgtacaggcatccccatgccgaagttcagatggaattctctacatgggtaaaaagcag
gacatttggtatgttattgatcttctgaccggggagaagcagcagactttgtcatcggcc
tttgcagacagtctctgcccatcaacctctctgctgtatctcgggcgaacagagtataca
atcaccatgtacgacaccaaaacccgcgagctccggtggaatgccacctacttcgactac
gcggcctcactgccggaggacgacggggactacaagatgtcccactttgtgtccaacggc
gatgggctggtggtgaccgtggacagtgaatctggcgacgtcctgtggatccaaaactat
gcttcccctgtggtggccttttatgtctggcagcgggagggtctgaggaaggtgatgcac
atcaacgtcgcagtggagacgctgcgctatctgaccttcatgtctggggaggtgggccgc
atcaccaagtggaagtacccgttccccaaggagacggaggccaagagcaagctgacgccc
accctgtatgtcgggaaatactctaccagcctgtatgcctccccctccatggtgcacgag
ggggtcgccgttgtgccccgaggcagcacacttcctttgctggaaggcccccagactgac
ggggtcaccattggggacaaaggggagtgtgtgatcacgcccagcacagacctaaagttt
gaccctgggctcaaagggaagagcaagctcaactacttgaggaactactggcttctgata
ggacaccatgaaacccccctgtctgcgtctaccaagatgctggagagattccccaataat
ctgcccaaacatcgagaaaatgtgattcctgccgattcagagaagaagagctttgaggaa
gttatcaacctggtcgagcagacttcagaaaacgcgcccaccgccgtttcacaggaggtg
gaggagaagttcgagcatgcccccgctaagcccgaggcccccgtggactctgtgctgaag
gacatagccaccatcatcctgagcaccttcctgctcatcggctgggtggccttcatcatc
acctaccccttgagcatgcatcagcagcagcagctccagcaccagcagttccagaaggaa
ctagagaaaatccagctcctgcaacagcagcagctgcccttccatccccctggagacgtg
gctcaggatgctgagctcctggactcgtccggcctgtactcagagagctcgggcaccagc
agccccagcacatcccccagagcctccaaccactcgctccactccagtggctctgcctcc
agggctggtgccagccccttcctggagcaggacgatgaagatgaggaaaccagcatggtg
attgttgggaagatctcattctgtcccaaggacgtgctgggccacggagctgagggcacg
attgtgtaccggggcatgttcgacaaccgcgatgtggccgtcaagaggatcctccccgag
tgtttcagtttcgcggaccgtgaggtccagctgcttcgggaatcagacgagcaccccaac
gtgattcgttacttctgcacggagagggaccggcagttccagtacattgccatcgagctg
tgtgcggccaccctgcaggagtacgtggagcagaaggacttcgcccacctcggcctggag
cccatcaccttgctgcagcagaccacctcgggcctggcccatttgcactccctcaacatt
gttcacagagacctgaagccccacaacattctcctgtccatgcccaacgcccatggcagg
atcaaggccatgatctctgacttcggcctctgcaagaagctggctgtgggcaggcacagt
ttcagccgccgctcaggagtgcctggcacagaaggctggatcgctccggagatgctgagc
gaggactgtaaggacaatcccacctacacagtggacatcttctctgcgggctgtgtcttt
tactatgtgatatctgagggcagccacccttttggcaagtccctgcagcggcaggccaac
atcctcctgggcgcctacagcctcgactgcctacacccggagaagcacgaagacgtcatt
gcccgggaattaatagagaagatgatcgcaatggatcctcagaaacgcccctctgcgaag
catgtgctgaagcacccgttcttctggagcctggaaaagcagctccagttcttccaggac
gtgagtgaccgaatagaaaaggaatccctggacggcccgatagtgaagcagctggagcga
ggcgggagagccgtggtaaagacggactggagagagaacatcaccgtccccctgcagaca
gatctgcgtaaattcagaacctataaaggtggctctgtccgcgaccttctccgagccatg
agaaacaagaagcaccactaccgggagctccccgcggaggtgcgggagacgctgggctct
ctccccgacgactttgtgcgctacttcacgtcccgcttcccccacctcctcccccacacc
taccgggccatggagccctgcagccacgagaggctcttccagccttactactgccacgag
cccccagagctccggccccccgtgactccagacgccctttga
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