KEGG   Panthera tigris altaica (Amur tiger): 102956633
Entry
102956633         CDS       T02988                                 
Symbol
FH
Name
(RefSeq) fumarate hydratase
  KO
K01679  fumarate hydratase, class II [EC:4.2.1.2]
Organism
ptg  Panthera tigris altaica (Amur tiger)
Pathway
ptg00020  Citrate cycle (TCA cycle)
ptg00620  Pyruvate metabolism
ptg01100  Metabolic pathways
ptg01200  Carbon metabolism
ptg04934  Cushing syndrome
ptg05200  Pathways in cancer
ptg05211  Renal cell carcinoma
Module
ptg_M00009  Citrate cycle (TCA cycle, Krebs cycle)
ptg_M00011  Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
Brite
KEGG Orthology (KO) [BR:ptg00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00020 Citrate cycle (TCA cycle)
    102956633 (FH)
   00620 Pyruvate metabolism
    102956633 (FH)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    102956633 (FH)
  09162 Cancer: specific types
   05211 Renal cell carcinoma
    102956633 (FH)
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    102956633 (FH)
Enzymes [BR:ptg01000]
 4. Lyases
  4.2  Carbon-oxygen lyases
   4.2.1  Hydro-lyases
    4.2.1.2  fumarate hydratase
     102956633 (FH)
SSDB
Motif
Pfam: Lyase_1 FumaraseC_C
Other DBs
NCBI-GeneID: 102956633
NCBI-ProteinID: XP_007077049
LinkDB
Position
Un
AA seq 510 aa
MYRVVRLLARSRRLVRPPGSASAPGLGPGAPAGILLLSPNKSRKASQNSFRIEFDTFGEL
KVPNDKYYGAQTVRSTMNFKIGGVTERMPIPVIKAFGILKRAAAEVNQDYGLDSKIANAI
MKAADEVAEGKLNDHFPLVVWQTGSGTQTNMNVNEVISNRAIEMLGGELGSKKPVHPNDH
VNKSQSSNDTFPTAMHIAAAVEVHEVLLPGLQKLHDALEAKSKEFAQIIKIGRTHTQDAV
PLTLGQEFSGYVQQVKYAMTRIKAAMPRIYELAAGGTAVGTGLNTRIGFAEKVAAKVAAL
TGLPFVTAANKFEALAAHDALVELSGAMNTTACSLMKIANDIRFLGSGPRSGLGELILPE
NEPGSSIMPGKVNPTQCEALTMVAAQVMGNHVAVTVGGSNGHFELNVFKPMMIKNVLHSA
RLLGDACVSFTENCVVGIQANTERINKLMNESLMLVTALNPHIGYDKAAKIAKTAHKNGS
TLKATAIELGYLTAEQFDEWVKPKDMLGPK
NT seq 1533 nt   +upstreamnt  +downstreamnt
atgtaccgcgtcgtccgactcctcgcgcgctcgcgtcgcctcgtgcggcctcccggctca
gcctcagctcccggcctcggcccaggcgcccctgctggcatcttgttgctgtctcctaac
aagtcacgtaaagcaagccaaaattcctttcggatagagtttgatacctttggtgaactc
aaggtcccaaatgataagtattatggcgcccagactgtgagatccacgatgaactttaaa
attggaggtgtgacggagcgcatgccaatcccagttattaaagcttttggaatcttgaag
cgagcggctgctgaagtaaaccaggattatggtcttgattcgaagattgctaatgcgata
atgaaggcagccgatgaggtagctgaaggtaaattaaatgatcattttccacttgtggta
tggcagactggatcaggaacccagacaaatatgaatgtaaatgaagtcattagcaataga
gcaattgaaatgctgggaggtgaacttggtagcaagaaacctgtgcatcccaatgatcac
gttaataaaagccagagttcgaatgatacctttcccacagcgatgcacattgctgctgct
gtagaagttcatgaggtgctcctgccagggctacagaagctgcatgatgctctcgaagcc
aaatccaaagagtttgcccagatcatcaaaattgggcgcactcacacccaggacgctgtt
ccactcactcttgggcaggaatttagtggttatgttcaacaagtgaaatatgcaatgacg
agaataaaagccgccatgccaagaatctatgagctcgcagctggaggcactgctgttggt
actggtttaaatactagaattggctttgcagaaaaggttgctgcaaaagtggctgcactc
acagggttgccttttgtcacagctgcaaataaatttgaagctctggctgctcatgatgct
ttggttgaactcagtggagccatgaatactaccgcctgcagtctgatgaagatagcaaac
gatattcgttttctgggttctggtcctcgctcaggtctgggagagctgatcttgcctgaa
aatgagccaggaagtagtatcatgccaggcaaggtgaaccctacgcagtgtgaagcgctc
accatggttgcagcccaggtcatggggaatcacgtcgccgttaccgttggaggcagcaat
ggacattttgagttgaatgttttcaagccaatgatgattaaaaatgtgttacactcagcc
aggctgctgggggacgcgtgcgtttccttcacagaaaactgcgttgtgggaatccaggcc
aacacagagaggatcaacaagctgatgaacgaatctctaatgttggtgacagctcttaat
cctcatatagggtatgacaaggcagcaaagattgctaagacagcacacaaaaatggatca
accttaaaggccactgccattgagcttggctatctcacagcagagcagtttgatgagtgg
gtaaaacctaaggacatgctgggtccaaagtga

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