Panthera tigris altaica (Amur tiger): 102960767
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Entry
102960767 CDS
T02988
Symbol
KIT
Name
(RefSeq) KIT proto-oncogene receptor tyrosine kinase
KO
K05091
proto-oncogene tyrosine-protein kinase Kit [EC:
2.7.10.1
]
Organism
ptg
Panthera tigris altaica (Amur tiger)
Pathway
ptg04010
MAPK signaling pathway
ptg04014
Ras signaling pathway
ptg04015
Rap1 signaling pathway
ptg04072
Phospholipase D signaling pathway
ptg04151
PI3K-Akt signaling pathway
ptg04640
Hematopoietic cell lineage
ptg04916
Melanogenesis
ptg05200
Pathways in cancer
ptg05221
Acute myeloid leukemia
ptg05224
Breast cancer
ptg05230
Central carbon metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
ptg00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
102960767 (KIT)
04014 Ras signaling pathway
102960767 (KIT)
04015 Rap1 signaling pathway
102960767 (KIT)
04072 Phospholipase D signaling pathway
102960767 (KIT)
04151 PI3K-Akt signaling pathway
102960767 (KIT)
09150 Organismal Systems
09151 Immune system
04640 Hematopoietic cell lineage
102960767 (KIT)
09152 Endocrine system
04916 Melanogenesis
102960767 (KIT)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
102960767 (KIT)
05230 Central carbon metabolism in cancer
102960767 (KIT)
09162 Cancer: specific types
05221 Acute myeloid leukemia
102960767 (KIT)
05224 Breast cancer
102960767 (KIT)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
ptg01001
]
102960767 (KIT)
09183 Protein families: signaling and cellular processes
04090 CD molecules [BR:
ptg04090
]
102960767 (KIT)
Enzymes [BR:
ptg01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
102960767 (KIT)
Protein kinases [BR:
ptg01001
]
Receptor tyrosine kinases (RTK)
PDGFR family [OT]
102960767 (KIT)
CD molecules [BR:
ptg04090
]
Proteins
102960767 (KIT)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
Ig_3
I-set
ig
Ig_2
C1-set
C2-set_2
Motif
Other DBs
NCBI-GeneID:
102960767
NCBI-ProteinID:
XP_007075953
LinkDB
All DBs
Position
Un
AA seq
1010 aa
AA seq
DB search
MRLKLRKLKLKEVKSSSSPTPNFTDGWVSVSQYHGDGPYSEWKLDPAGVFSPEKAMASSS
SQPSVSPGERSLPSIHPATSELIVSVGDEIRLLCTDPGFVKWTFETLGQSSEITHNEWIT
EKAEATNTGNYTCTNGGGLSSSIYVFVRDPAKLFLVDLPLYGKEDHDTLVRCPLTDPEVT
NYSLRGCEGKPLPKDLTFVTDPKAGITIRNVKREYHRLCLHCSADRKGKSVLSKKFTLKV
RAAIRAVPVVSVSKASHLLREGEEFSVMCLIKDVSSSVDSMWIKENSPQTNAQPQSNSWH
QGDFNFVRQERLTISSARVNDSGVFMCYANNTFGSANVTTTLEVVAKGFIHIFPMMNTTI
FVNDGENVDLIVEYEAYPKPEHQRWVYMNRTLTDKWEDYPKSDNESNIRYVSELHLTRLK
GNEGGTYTFQVSNSDVNSSVTLNVYVNTKPEILTHESLVSGILQCLVAGFPEPTVDWYFC
PGTEQRCPVPVGPLDVQMQNSSVSPSGKLVVQSSIDYSAFKHNGTVECRASNNVGKTSAF
FNFAFKEQMHPHTLFTPLLIGFVIAAGMMCIIVMILTYKYLQKPMYEVQWKVVEEINGNN
YVYIDPTQLPYDHKWEFPRNRLSFGKTLGAGAFGKVVEATAYGLIKSDAAMTVAVKMLKP
SAHLTEREALMSELKVLSYLGNHMNIVNLLGACTVGGPTLVITEYCCYGDLLNFLRRKRD
SFICSKQEDHAEVALYKNLLQSKESSCNDSTNEYMDMKPGVSYVVPTKADKRRSARIGSY
IERDVTPAIMEDDELALDLEDLLSFSYQVAKGMAFLASKNCIHRDLAARNILLTHGRITK
ICDFGLARDIKNDSNYVVKGNARLPVKWMAPESIFNCVYTFESDVWSYGIFLWELFSLGS
SPYPGMPVDSKFYKMIKEGFRMLSPEHAPAEMYDIMKTCWDADPLKRPTFKQIVQLIEKQ
ISDSTNHIYSNLANCSPNRERPTAVDHCVRINSVGSSTSSTQPLLVHEDA
NT seq
3033 nt
NT seq
+upstream
nt +downstream
nt
atgcgcctgaagttaaggaagttaaagttgaaagaagtcaagagctcctcctcccccacc
ccaaacttcaccgatggctgggtgtcagtaagtcagtaccacggcgatggcccctattca
gagtggaaacttgacccagctggggtgtttagcccagagaaggccatggcatccagctct
tctcaaccatctgtgagtccaggggaacggtctctaccatccatccatccagcaacatca
gagttaatagtcagtgttggcgacgagattaggctgttgtgcaccgatccaggatttgtc
aaatggacttttgagaccctgggccagtcgagtgagatcacacacaatgaatggatcacg
gagaaagcagaggccaccaacacaggcaattacacgtgcaccaacggaggcggcttaagc
agttccatttacgtgtttgttagagatcccgcaaagcttttcctcgttgaccttcccttg
tatgggaaagaagaccatgatacgctggtccgctgtcctctgacagacccagaggtgacc
aattactccctccgggggtgcgaggggaagcctcttcccaaggacttgactttcgtcacc
gatcccaaggctggcatcacaatcaggaacgtgaagcgcgagtaccatcggctgtgcctg
cattgctctgcggaccggaagggcaagtccgtgctgtcgaagaaattcaccctgaaagtg
agggcagccatcagagctgtcccagttgtgtctgtgtccaaagcaagccatcttcttagg
gaaggggaagaattctccgtgatgtgcttgataaaagatgtgtctagttccgtggactcg
atgtggatcaaggaaaacagcccgcaaactaacgcacagccacagagtaatagctggcac
caaggtgacttcaattttgtacgtcaggaaaggttgacgatcagctcagcaagagttaac
gattctggagtgttcatgtgttatgccaataatacttttggatcggcaaatgtcacaaca
accttggaagtcgtagctaaaggattcattcacatcttcccgatgatgaataccacaata
ttcgtgaatgacggagagaatgtggatctgattgtcgaatatgaggcatatcccaagcct
gagcaccaacggtgggtctatatgaacagaaccctcactgataaatgggaagattatccc
aagtctgacaacgaaagtaatatcagatatgtgagtgaacttcacctaaccagattaaaa
gggaacgaaggaggcacttacacgtttcaagtgtccaattccgatgtcaattcttccgtg
acattgaatgtttacgtgaacacaaaaccagaaatcctgactcatgaaagtctcgtgagt
ggcatactacagtgtttggtagctggattcccggagcccacagtagattggtatttttgt
ccaggaactgagcagagatgtcctgttcctgttgggccactggatgtgcagatgcaaaac
tcatctgtatcgccgtctggaaaactagtggttcaaagttccatcgattacagtgctttc
aaacacaatggcacagtcgagtgtagggcttccaacaatgtgggcaagacttctgccttt
tttaactttgcatttaaagaacaaatgcatcctcacaccctgttcacacctttgctgatt
ggttttgtgatcgcagctggtatgatgtgtattatcgtgatgatacttacctacaaatat
ttacagaaacccatgtatgaagtgcagtggaaggttgtcgaggagataaatggaaacaat
tatgtttacatagacccaacacagcttccttacgatcacaaatgggagtttcccagaaac
aggctgagttttgggaaaaccttgggtgccggtgccttcgggaaggtggttgaggccact
gcatatggcctgattaagtcggatgcggccatgaccgttgctgttaagatgctcaaacca
agtgcccatttaaccgaacgagaagccctcatgtccgagctcaaagtcttgagttacctc
ggcaatcacatgaatattgtgaatcttctcggagcatgcaccgttggagggcccaccctg
gtcattactgagtattgttgctatggtgatcttttgaattttttgagaagaaaacgcgat
tcatttatttgctcaaagcaggaagatcatgcagaagtggcactttataagaaccttctg
cagtcaaaggagtcttcctgcaacgatagtactaatgagtacatggacatgaaacccggc
gtttcttatgttgtgccaaccaaggcagacaaaaggagatccgccagaataggctcatac
atagaaagagatgtgactcccgccatcatggaggacgatgagttggctctagacctggag
gacttgctgagcttctcgtaccaggtggccaagggcatggcattcctcgcctcgaagaat
tgtattcacagagacttggctgctagaaatatcctccttactcatggtcgaatcacaaag
atttgtgattttggtctagccagagacatcaagaatgattctaattatgtggtcaaagga
aacgctcggctacctgtgaagtggatggcacctgaaagcattttcaactgtgtgtacaca
tttgaaagtgatgtctggtcctatgggatttttctgtgggagctgttctctttaggaagc
agcccctaccctggaatgccagtcgactctaagttctacaagatgatcaaggaagggttc
cgaatgctcagccctgagcacgcacctgctgaaatgtatgacataatgaagacttgctgg
gatgctgatcccctgaaaaggccaacattcaagcagatcgtgcagctaatcgagaagcag
atttcagatagcaccaatcatatttattccaacttagcaaactgcagcccgaaccgggag
cgccccacagcggtggaccattgtgtgcggatcaattctgtgggcagcagcacatcttct
acccagcctctgctggtccacgaggatgcctga
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