KEGG   Panthera tigris altaica (Amur tiger): 102962011
Entry
102962011         CDS       T02988                                 
Symbol
EIF2S1
Name
(RefSeq) eukaryotic translation initiation factor 2 subunit alpha
  KO
K03237  translation initiation factor 2 subunit 1
Organism
ptg  Panthera tigris altaica (Amur tiger)
Pathway
ptg04137  Mitophagy - animal
ptg04140  Autophagy - animal
ptg04141  Protein processing in endoplasmic reticulum
ptg04156  Integrated stress response (ISR) signaling pathway
ptg04210  Apoptosis
ptg04932  Non-alcoholic fatty liver disease
ptg05010  Alzheimer disease
ptg05012  Parkinson disease
ptg05014  Amyotrophic lateral sclerosis
ptg05020  Prion disease
ptg05022  Pathways of neurodegeneration - multiple diseases
ptg05160  Hepatitis C
ptg05162  Measles
ptg05164  Influenza A
ptg05168  Herpes simplex virus 1 infection
ptg05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:ptg00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04141 Protein processing in endoplasmic reticulum
    102962011 (EIF2S1)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    102962011 (EIF2S1)
   04137 Mitophagy - animal
    102962011 (EIF2S1)
  09143 Cell growth and death
   04210 Apoptosis
    102962011 (EIF2S1)
   04156 Integrated stress response (ISR) signaling pathway
    102962011 (EIF2S1)
 09160 Human Diseases
  09172 Infectious disease: viral
   05160 Hepatitis C
    102962011 (EIF2S1)
   05164 Influenza A
    102962011 (EIF2S1)
   05162 Measles
    102962011 (EIF2S1)
   05168 Herpes simplex virus 1 infection
    102962011 (EIF2S1)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    102962011 (EIF2S1)
   05012 Parkinson disease
    102962011 (EIF2S1)
   05014 Amyotrophic lateral sclerosis
    102962011 (EIF2S1)
   05020 Prion disease
    102962011 (EIF2S1)
   05022 Pathways of neurodegeneration - multiple diseases
    102962011 (EIF2S1)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    102962011 (EIF2S1)
  09167 Endocrine and metabolic disease
   04932 Non-alcoholic fatty liver disease
    102962011 (EIF2S1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03012 Translation factors [BR:ptg03012]
    102962011 (EIF2S1)
   04131 Membrane trafficking [BR:ptg04131]
    102962011 (EIF2S1)
Translation factors [BR:ptg03012]
 Eukaryotic type
  Initiation factors
   eIF-2
    102962011 (EIF2S1)
Membrane trafficking [BR:ptg04131]
 Autophagy
  ER-phagy
   ER stress-related proteins
    102962011 (EIF2S1)
SSDB
Motif
Pfam: EIF_2_alpha S1 DUF4446
Other DBs
NCBI-GeneID: 102962011
NCBI-ProteinID: XP_007095234
UniProt: A0A8C9KIN4
LinkDB
Position
Un
AA seq 315 aa
MPGLSCRFYQHKFPEVEDVVMVNVRSIAEMGAYVSLLEYNNIEGMILLSELSRRRIRSIN
KLIRIGRNECVVVIRVDKEKGYIDLSKRRVSPEEAIKCEDKFTKSKTVYSILRHVAEVLE
YTKDEQLESLFQRTAWVFDDKYKRPGYGAYDAFKHAVSDPSILDSLDLNEDERGVLINNI
NRRLTPQAVKIRADIEVACYGYEGIDAVKEALRAGLNCSTETMPIKINLIAPPRYVMTTT
TLERTEGLSVLNQAMAVIKEKIEEKRGVFNVQMEPKVVTDTDETELARQLERLERENAEV
DGDDDAEEMEAKAED
NT seq 948 nt   +upstreamnt  +downstreamnt
atgccgggtctaagttgtagattttatcaacacaaatttcctgaggtggaagatgtagtg
atggtgaacgtaaggtccattgctgaaatgggggcttatgtcagcttgctggaatacaac
aatattgaaggcatgattcttcttagtgagttgtccagaaggcgtatccgttctataaac
aaactcatcagaattggcaggaatgaatgtgtggtagtcattagagtggacaaagaaaaa
ggatatattgatttgtcaaaaagaagagtttctccagaggaagcaatcaaatgtgaagat
aaattcaccaaatccaaaactgtttacagtattcttcgtcatgttgctgaggtgttagag
tacaccaaggacgagcagctggagagcctgttccagaggactgcctgggtctttgatgac
aaatacaagagacccggatacggtgcctatgatgcatttaagcatgcagtctcagaccca
tctattttggatagtttagatttgaatgaagatgaacggggagtacttattaacaatatt
aataggcgtttgacaccacaagctgtcaaaattcgagcagatattgaagtggcttgttat
ggttatgaaggcattgatgctgtaaaagaagccctgagagcaggtttgaattgttctaca
gaaaccatgcccatcaagattaatctaatagctcctcctagatatgtgatgacaacaaca
accctggagagaacagagggcctctctgtcctcaatcaagctatggctgttataaaagaa
aagattgaggaaaagaggggtgtcttcaatgtccaaatggagcctaaagtggtcacagat
acagatgagaccgaacttgcaaggcagcttgagaggcttgagagagagaatgcagaagtg
gatggagacgatgatgcagaagaaatggaagccaaagccgaagattaa

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