Panthera tigris altaica (Amur tiger): 102965157
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Entry
102965157 CDS
T02988
Symbol
NPC1
Name
(RefSeq) NPC intracellular cholesterol transporter 1
KO
K12385
Niemann-Pick C1 protein
Organism
ptg
Panthera tigris altaica (Amur tiger)
Pathway
ptg03265
Virion - Ebolavirus, Lyssavirus and Morbillivirus
ptg04142
Lysosome
ptg04979
Cholesterol metabolism
Brite
KEGG Orthology (KO) [BR:
ptg00001
]
09120 Genetic Information Processing
09125 Information processing in viruses
03265 Virion - Ebolavirus, Lyssavirus and Morbillivirus
102965157 (NPC1)
09140 Cellular Processes
09141 Transport and catabolism
04142 Lysosome
102965157 (NPC1)
09150 Organismal Systems
09154 Digestive system
04979 Cholesterol metabolism
102965157 (NPC1)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
02000 Transporters [BR:
ptg02000
]
102965157 (NPC1)
Transporters [BR:
ptg02000
]
Solute carrier family (SLC)
SLC65: NPC-type cholesterol transporter
102965157 (NPC1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
NPC1_MLD
NPC1_N
Sterol-sensing
Patched
MMPL
ACR_tran
Motif
Other DBs
NCBI-GeneID:
102965157
NCBI-ProteinID:
XP_007076075
LinkDB
All DBs
Position
Un
AA seq
1296 aa
AA seq
DB search
MIARPCRPVALASVVDLRGCADVMIHAAPSSPSEFSDSLVLAQSCIWYGECGIASGDKRY
NCKYSGPPKPLPKDGYDLVQELCPGFFFDNVSLCCDVQQLQTLKDNLQLPLQFLSRCPSC
FYNLMNLFCELTCSPRQSQFLNVTATEDYVDPVTNQTKTNVKELQYYIGESFANAMYNAC
RDVEAPSSNDKALGLLCGKDAEACNATNWIEYMFNKDNGQAPFTITPIFSDLPTHGMEPM
NNATKGCDESVDEVTGPCSCQDCSIVCGPKPQPPPPPVPWRILGLDAMYVIMWITYMAFL
LVFFGAFFALWCYRKRYFVSEYTPIDSNIAFSVNANDRGEASCCDALGAAFEGYLRRLFS
QWGSFCVRNPGPIIIFSLAFIAACSSGLVFVRVTTNPVDLWSAPSSQARLEKEYFDTHFG
PFFRTEQLIIQAPHTSAHTYQPYPSGSDVPFGPPLDLAILHQVLDLQTAIENITASYNNE
TVTLQDICVAPLSPYNKNCTILSVLNYFQNSHSMLDHEIGDDFFVYADYHTHLLYCVRAP
ASLNDTSLLHDPCLGTFGGPVFPWLVLGGYDDQNYNNATALVITFPVNNYYNDTERLQKA
QVWEKEFINFVKNYKNPNLTISFTTERSIEDELNRESNGDIFTVIISYAIMFLYISIALG
HIKSCSRLLVDSKISLGIAGILIVLSSVACSLGIFSYIGIPLTLIVIEVIPFLVLAVGVD
NIFILVQTYQRDERLHGETLDQQLGRVLGEVAPSMFLSSFSEAVAFFLGALSKMPAVHTF
SLFAGMAVLIDFLLQITCFVSLLGLDIKRQEKNRLDVLCCVRGSEDGTSVQASESCLFRL
FKHSYSPLLLKDWMRPIVIAVFVGVLSFSVAVLNKVEIGLDQSLSMPDDSYVMDYFKSLK
YLHAGPPVYFVLEEGHDYTSLKGQNMVCGGMGCNNDSLVQQIFNAAQLDSYTRIGFAPSS
WIDDYFDWVKPQSSCCRVYNSTDRFCNASVVDPACIRCRPLTQEGKQRPQGGDFMRFLPM
FLSDNPNPKCGKGGHAAYSSAVNILGNDTGVGATYFMTYHTVLQTSADFTDAMRKANLIA
SNITKTMGLEGSNYRVFPYSVFYVFYEQYLTIIDDTIFNLGVSLGAIFLVTVILLGCDLW
SAVIMCITIAMILVNMFGVMWLWGISLNAVSLVNLVMSCGISVEFCSHITRAFTVSMKGS
RAQRAEEALAHMGSSVFSGITLTKFGGIVVLAFAKSQIFQIFYFRMYLAMVLLGATHGLI
FLPVLLSYIGPSINKAKSLATQEQYKGTEREQLLNF
NT seq
3891 nt
NT seq
+upstream
nt +downstream
nt
atgattgcaaggccttgcaggcctgtggccctggccagtgtggtggatctccgtggctgt
gctgacgtgatgattcacgctgcaccctcctccccttctgagttttcagacagcctggtg
ttggcacagtcttgcatctggtatggagagtgtggaattgcatctggagataagaggtac
aactgcaaatattcagggccaccaaaacccttgccgaaggatgggtatgacttagtgcag
gagctctgtccaggattcttctttgacaacgtcagtctttgttgcgatgtgcagcagctc
cagacactgaaagacaacctgcagctgcctctacagtttctgtccagatgtccatcctgt
ttctataacctaatgaacctgttttgcgagctgacgtgtagccctcggcaaagtcagttt
ctgaatgttacagcaactgaagattatgttgatcctgttacaaaccagactaaaacaaat
gtaaaagaattacagtactacattggagagagttttgccaatgccatgtacaatgcctgc
cgggacgtggaggccccctccagtaatgacaaagccctgggactgctgtgtgggaaggac
gccgaagcctgcaatgccactaactggattgagtacatgttcaataaggacaacggccag
gcacctttcaccatcacacccattttttcagatcttccaacccatgggatggagcccatg
aacaatgccaccaagggctgtgacgagtctgtggacgaagtcaccgggccgtgcagctgc
caggactgctcaattgtttgtggcccaaagccccagcccccaccgcctcctgtgccctgg
agaatcttgggcctggacgccatgtatgtcatcatgtggatcacctacatggcatttttg
cttgtgttttttggagcattttttgctttgtggtgctacagaaaacgctattttgtctcc
gagtacacccccattgatagcaacatagctttctctgtaaatgccaatgacagaggggag
gcgtcctgctgcgacgcgcttggtgcggcatttgagggctatctgaggcggctcttctca
cagtggggctctttctgcgtccgaaacccgggccccatcatcatcttctccctggccttc
attgccgcctgttcttcaggcctggtgtttgtgcgggtcacgaccaatccagttgacctg
tggtcagctcccagcagccaggcgcgcctcgagaaagagtactttgacacacactttggg
cctttcttccgcacggagcagctcatcatccaggccccccacaccagcgcacacacttac
cagccgtacccctcaggatccgatgtgcccttcggacctccgcttgaccttgcgatcttg
caccaggttcttgacttacaaactgccatcgaaaatatcactgcatcttataacaatgag
actgtgacacttcaagacatctgcgtggcccccctctcaccctataacaagaactgcacc
attctgagcgtgttaaattacttccagaacagccattccatgctggaccatgaaatagga
gatgacttctttgtgtatgcagattaccacacgcacttgctatactgtgtacgggctcct
gcctctctgaacgataccagtttgctccatgatccttgcctgggtacattcggtgggcca
gtgttcccgtggcttgtgttaggaggctatgatgatcaaaattacaataatgccacagcc
cttgtgattacctttcctgtcaataattactataatgatacagagaggctccagaaggcc
caggtctgggaaaaagagtttattaattttgtgaaaaactacaagaatccaaatctgacc
atttctttcactactgagcgaagtattgaagatgaactaaatcgtgaaagtaacggtgat
attttcactgttataatcagctatgccatcatgtttctgtacatttccatagccttgggg
cacatcaaaagctgtagcaggcttctagtggactctaaaatctccctcggcatcgcgggg
atcctcattgtgttgagctcagtggcgtgctcgttgggcatctttagctacattgggatc
cccctcaccctcattgtgatcgaagtcatcccattcctggtgctggctgttggggtggac
aacatcttcattctggtccagacctaccagcgagatgaacgtcttcacggagaaactctg
gatcagcagctgggcagggtcctaggagaagtggctcctagtatgttcctgtcatccttt
tcagaggctgtagcatttttcttaggagcgctgtcaaagatgccggctgttcacaccttc
tctctgtttgccgggatggcagtcctcatcgacttccttcttcagattacctgtttcgtg
agtctcttggggttagacattaagcgtcaagagaaaaaccgtctggatgttctttgctgt
gtcagaggctctgaagatggaaccagtgtccaggcttcagagagctgcttgtttcggctc
ttcaagcactcctattctccacttctgcttaaggactggatgagaccaattgtgatagcg
gtatttgtgggtgtcctgtcattcagtgttgcagtcctgaacaaagtggaaatcggattg
gatcagtctctttcaatgccagatgactcctacgtgatggattatttcaagtccctcaaa
tacctgcatgcaggtccacctgtgtactttgtcctggaggaagggcatgactacacctct
ctgaaagggcagaacatggtgtgcggaggcatgggctgcaataacgactccctggtgcag
cagatattcaacgcggcgcagctagacagctatacccgaataggctttgctccctcttcc
tggatcgacgattactttgattgggtcaagcctcagtcttcttgctgtagagtctacaac
agcaccgatcggttctgcaatgcttcagtggttgaccctgcctgcatccgctgcaggccc
ctcacccaggagggcaaacagaggcctcaaggtggagacttcatgagattcctgcccatg
ttcctttctgataacccgaaccccaagtgcggcaaagggggacatgctgcttacagttcg
gcagttaacatcctcggcaatgacacgggtgtcggagccacttacttcatgacctaccac
accgtgcttcagacgtctgctgactttactgacgccatgagaaaagccaacctcatcgcc
agtaacatcaccaaaaccatgggccttgaaggaagtaattaccgtgtgttcccatacagt
gtgttctatgtcttctacgaacagtacttgaccattattgatgacacgatctttaacctc
ggcgtgtccctgggagccatattcttggtgaccgtgattctcctgggctgtgatctgtgg
tctgcagtgatcatgtgtatcaccatcgctatgatcttggtcaacatgtttggcgtcatg
tggctgtggggcatcagtctgaatgcagtttccttggtcaacttggttatgagctgtggc
atttccgtggagttctgcagccacataacgagagcattcacggtgagcatgaagggcagc
cgtgcacaacgggcagaagaggcgctcgctcacatgggcagttctgtgttcagtggaatc
acactaacaaaatttggagggattgtggtattggcctttgccaaatctcagattttccag
atattttacttcaggatgtatttggctatggtcttactgggagccacccacggcttgatc
ttcctcccggtcttactcagctacataggcccatcaataaataaagccaaaagcttggcc
actcaagagcaatacaaaggtacagagcgagaacaactcctaaatttctag
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