Panthera tigris altaica (Amur tiger): 102966497
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Entry
102966497 CDS
T02988
Symbol
DOT1L
Name
(RefSeq) DOT1 like histone lysine methyltransferase
KO
K11427
[histone H3]-lysine79 N-trimethyltransferase [EC:
2.1.1.360
]
Organism
ptg
Panthera tigris altaica (Amur tiger)
Pathway
ptg00310
Lysine degradation
ptg01100
Metabolic pathways
ptg05202
Transcriptional misregulation in cancer
Brite
KEGG Orthology (KO) [BR:
ptg00001
]
09100 Metabolism
09105 Amino acid metabolism
00310 Lysine degradation
102966497 (DOT1L)
09160 Human Diseases
09161 Cancer: overview
05202 Transcriptional misregulation in cancer
102966497 (DOT1L)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
ptg03036
]
102966497 (DOT1L)
Enzymes [BR:
ptg01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.360 [histone H3]-lysine79 N-trimethyltransferase
102966497 (DOT1L)
Chromosome and associated proteins [BR:
ptg03036
]
Eukaryotic type
Histone modification proteins
HMTs (histone methyltransferases)
HKMTs (histone lysine methyltransferases)
102966497 (DOT1L)
HMT complexes
Dot1-containing complex
102966497 (DOT1L)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
DOT1
Motif
Other DBs
NCBI-GeneID:
102966497
NCBI-ProteinID:
XP_015399821
LinkDB
All DBs
Position
Un
AA seq
804 aa
AA seq
DB search
MENYVLIDYDTKSFESMQRLCDKYNRAIDSIHQLWKGTTQPMKLNTRPSNGLLRHILQQV
YNHSVTDPEKLNNYEPFSPEVYGETSFDLVAQMIDEIKMTEDDLFVDLGSGVGQVVLQVA
AATNCKHHYGVEKADIPAKYAEVSDPGVIACTYPEVEAPIAEVHLALREGAGNGIWLEGR
WGTASEWCVDERLAVPLAFCCRPPRGPAPAGCGGFVPTMSAQIWRELVSWGCEGSPAERK
PHPHRELASSIQAQGSRLWLRWRWDISAVLFRPQGPPPGEQPRERGSADRTRVGGQTDER
APGRPPGVTGGRAVGCALVGEVGRELWLYREVVYAVLTLSAHLGPGREAPGSALLFSRSL
QFLKLQELSRLLDGLHLTSALPARGPMGEPPAGTFGSEVSTVGPRTVVTGEQLVCVSGGR
IVSSKPFAPLNFRINSRNLSDIGTIMRVVELSPLKGSVSWTGKPVSYYLHTIDRTILENY
FSSLKNPKLRRPRPPTPLSEGPHGVTSAVKSSRFRLESFKIQYLQFLAYTKTAQYKASLQ
QLLDQEKEKNARLLGATQQLFGHCQAQKEEIKRLFQQKLDEVGRSTPSPVPQTRESLSTL
EKQMGTNAHSAGSKSLAPAPAGRWAPPAPGSLPLALPPWPSWPTSSRPRGLRCCIGAVVT
QHDHPGGGPQPVGDVLIKLLWAFLARCRFSFRERQWLRPHAPAEAPRTFCSSQVSNINQP
LEITAISSPESLKSSPVPYQDSDQPPVLKKEKPLSQTNGAHYSPLTSDEEQGSEDEPGST
RIERKIATISLESRSPPKTLENGE
NT seq
2415 nt
NT seq
+upstream
nt +downstream
nt
atggagaactacgttttaatcgactacgacaccaaaagcttcgagagcatgcagaggctc
tgtgataagtacaaccgcgccatcgacagcatccaccagctgtggaaggggaccactcag
cccatgaaactgaacacccggccgtccaacgggctcctgcggcacatcctgcagcaggtg
tataaccactcggtgacggaccccgagaagctcaacaactacgagcccttctccccggag
gtgtacggggagacctcctttgacctggtcgcgcagatgatcgacgagatcaagatgacc
gaggacgacctgtttgtggacctgggcagcggagtgggccaggtcgtgctccaggtggcc
gcggccaccaactgcaaacatcactacggcgtggagaaagccgacatcccagccaagtac
gcggaggtgagtgaccctggagtcatcgcctgcacgtacccagaggtcgaggccccgatc
gctgaggtccacttggctctgcgcgaaggggctgggaatgggatttggctggaaggacgc
tggggcacggcctcggagtggtgcgtggacgagcggctggccgtgcccctggcgttctgt
tgccggcctccacgcggcccagctccagcagggtgtggtggatttgtgccgaccatgagc
gcccagatctggcgggaacttgtgtcctggggatgtgagggctctccagcggagaggaag
ccccatcctcaccgagagctggctagcagcatccaggcccaggggtcccgtctctggttg
cgctggcgatgggacatctctgcggtcctgtttcggccccaggggcctcctcctggcgag
cagcctcgggagcggggttccgctgatcggacccgggtgggcggccagactgacgagcgg
gccccaggccgtcctccgggcgtgaccggtggtcgcgcggtggggtgtgccctggtgggg
gaagtgggccgtgagctgtggctgtaccgtgaggttgtgtatgccgtcctcacgctgtcg
gcccacctgggacctggacgggaagccccaggaagtgccctcctctttagccggtcacta
cagttcctaaagctacaagaactttctagactcctagatggcctgcatctgacctcagcg
ctcccagccagggggcctatgggtgagcccccagctgggaccttcgggtccgaggtcagc
accgtggggcctcggaccgttgtcacgggagagcagctggtttgtgtttcaggtggcaga
attgtgtcctcgaagccctttgcgcctctgaacttcagaataaacagcagaaacttgagc
gacatcggcaccatcatgcgcgtcgtggagctctcgcccctgaagggctctgtgtcctgg
acggggaagccagtctcctactacctgcacaccatcgaccgcaccatacttgaaaactat
ttttctagtctgaaaaacccaaaactcaggcggccacgccctcccacgccgctttctgaa
gggccccacggggtcacgtctgcagtgaagtcatctcgcttccgcctagaatccttcaag
attcagtacctgcagttcttggcctacaccaagaccgcccagtacaaggccagccttcag
cagctgctggaccaggagaaggagaagaacgcccggctgctgggggccacacagcagctg
ttcggccactgccaggcccagaaagaggagatcaagaggctcttccagcagaaactggat
gaggtagggagaagcacccccagccccgtgccgcagacccgagagtccttgtccacactt
gaaaagcagatgggcactaatgcacacagcgccggaagcaaaagtctcgccccagcccct
gcaggtcggtgggctcctcctgctcctgggtccctgcccctggcccttcccccgtggccc
agctggcccacctcctcccggccgcggggtctgaggtgttgcatcggggctgtcgtcacg
caacacgaccacccaggaggtgggcctcagccggtaggcgatgtcctcatcaagctgctg
tgggcgtttctagcccggtgccggttctccttcagggagcgccagtggttgaggccgcac
gcgccggcagaggccccacggactttctgtagcagccaggttagcaacattaaccagcct
ttggaaatcacggccatttcgtcccctgagagcctgaagagctcccctgtcccctaccag
gacagcgaccagccgcccgtcctcaagaaggagaagcccctgagccagaccaacggggcc
cactactccccactgacctcggacgaggagcagggctccgaggacgagccgggcagcacc
agaattgagagaaaaattgcgacaatctccttagaaagcagatctcctccgaaaaccttg
gaaaacggtgagtga
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integrated database retrieval system
