KEGG   Panthera tigris altaica (Amur tiger): 102968561
Entry
102968561         CDS       T02988                                 
Symbol
RAC1
Name
(RefSeq) ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
  KO
K04392  Ras-related C3 botulinum toxin substrate 1
Organism
ptg  Panthera tigris altaica (Amur tiger)
Pathway
ptg04010  MAPK signaling pathway
ptg04014  Ras signaling pathway
ptg04015  Rap1 signaling pathway
ptg04024  cAMP signaling pathway
ptg04062  Chemokine signaling pathway
ptg04071  Sphingolipid signaling pathway
ptg04145  Phagosome
ptg04148  Efferocytosis
ptg04151  PI3K-Akt signaling pathway
ptg04310  Wnt signaling pathway
ptg04360  Axon guidance
ptg04370  VEGF signaling pathway
ptg04380  Osteoclast differentiation
ptg04510  Focal adhesion
ptg04520  Adherens junction
ptg04530  Tight junction
ptg04613  Neutrophil extracellular trap formation
ptg04620  Toll-like receptor signaling pathway
ptg04650  Natural killer cell mediated cytotoxicity
ptg04662  B cell receptor signaling pathway
ptg04664  Fc epsilon RI signaling pathway
ptg04666  Fc gamma R-mediated phagocytosis
ptg04670  Leukocyte transendothelial migration
ptg04722  Neurotrophin signaling pathway
ptg04810  Regulation of actin cytoskeleton
ptg04932  Non-alcoholic fatty liver disease
ptg04933  AGE-RAGE signaling pathway in diabetic complications
ptg04972  Pancreatic secretion
ptg05014  Amyotrophic lateral sclerosis
ptg05020  Prion disease
ptg05022  Pathways of neurodegeneration - multiple diseases
ptg05100  Bacterial invasion of epithelial cells
ptg05132  Salmonella infection
ptg05135  Yersinia infection
ptg05163  Human cytomegalovirus infection
ptg05167  Kaposi sarcoma-associated herpesvirus infection
ptg05169  Epstein-Barr virus infection
ptg05170  Human immunodeficiency virus 1 infection
ptg05200  Pathways in cancer
ptg05203  Viral carcinogenesis
ptg05205  Proteoglycans in cancer
ptg05208  Chemical carcinogenesis - reactive oxygen species
ptg05210  Colorectal cancer
ptg05211  Renal cell carcinoma
ptg05212  Pancreatic cancer
ptg05231  Choline metabolism in cancer
ptg05415  Diabetic cardiomyopathy
ptg05416  Viral myocarditis
ptg05417  Lipid and atherosclerosis
ptg05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:ptg00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    102968561 (RAC1)
   04014 Ras signaling pathway
    102968561 (RAC1)
   04015 Rap1 signaling pathway
    102968561 (RAC1)
   04310 Wnt signaling pathway
    102968561 (RAC1)
   04370 VEGF signaling pathway
    102968561 (RAC1)
   04071 Sphingolipid signaling pathway
    102968561 (RAC1)
   04024 cAMP signaling pathway
    102968561 (RAC1)
   04151 PI3K-Akt signaling pathway
    102968561 (RAC1)
 09140 Cellular Processes
  09141 Transport and catabolism
   04145 Phagosome
    102968561 (RAC1)
   04148 Efferocytosis
    102968561 (RAC1)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    102968561 (RAC1)
   04520 Adherens junction
    102968561 (RAC1)
   04530 Tight junction
    102968561 (RAC1)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    102968561 (RAC1)
 09150 Organismal Systems
  09151 Immune system
   04613 Neutrophil extracellular trap formation
    102968561 (RAC1)
   04620 Toll-like receptor signaling pathway
    102968561 (RAC1)
   04650 Natural killer cell mediated cytotoxicity
    102968561 (RAC1)
   04662 B cell receptor signaling pathway
    102968561 (RAC1)
   04664 Fc epsilon RI signaling pathway
    102968561 (RAC1)
   04666 Fc gamma R-mediated phagocytosis
    102968561 (RAC1)
   04670 Leukocyte transendothelial migration
    102968561 (RAC1)
   04062 Chemokine signaling pathway
    102968561 (RAC1)
  09154 Digestive system
   04972 Pancreatic secretion
    102968561 (RAC1)
  09156 Nervous system
   04722 Neurotrophin signaling pathway
    102968561 (RAC1)
  09158 Development and regeneration
   04360 Axon guidance
    102968561 (RAC1)
   04380 Osteoclast differentiation
    102968561 (RAC1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    102968561 (RAC1)
   05205 Proteoglycans in cancer
    102968561 (RAC1)
   05208 Chemical carcinogenesis - reactive oxygen species
    102968561 (RAC1)
   05203 Viral carcinogenesis
    102968561 (RAC1)
   05231 Choline metabolism in cancer
    102968561 (RAC1)
  09162 Cancer: specific types
   05210 Colorectal cancer
    102968561 (RAC1)
   05212 Pancreatic cancer
    102968561 (RAC1)
   05211 Renal cell carcinoma
    102968561 (RAC1)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    102968561 (RAC1)
   05163 Human cytomegalovirus infection
    102968561 (RAC1)
   05167 Kaposi sarcoma-associated herpesvirus infection
    102968561 (RAC1)
   05169 Epstein-Barr virus infection
    102968561 (RAC1)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    102968561 (RAC1)
   05135 Yersinia infection
    102968561 (RAC1)
   05100 Bacterial invasion of epithelial cells
    102968561 (RAC1)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    102968561 (RAC1)
   05020 Prion disease
    102968561 (RAC1)
   05022 Pathways of neurodegeneration - multiple diseases
    102968561 (RAC1)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    102968561 (RAC1)
   05418 Fluid shear stress and atherosclerosis
    102968561 (RAC1)
   05415 Diabetic cardiomyopathy
    102968561 (RAC1)
   05416 Viral myocarditis
    102968561 (RAC1)
  09167 Endocrine and metabolic disease
   04932 Non-alcoholic fatty liver disease
    102968561 (RAC1)
   04933 AGE-RAGE signaling pathway in diabetic complications
    102968561 (RAC1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:ptg04131]
    102968561 (RAC1)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:ptg04147]
    102968561 (RAC1)
   04031 GTP-binding proteins [BR:ptg04031]
    102968561 (RAC1)
Membrane trafficking [BR:ptg04131]
 Exocytosis
  Small GTPases and associated proteins
   Rho GTPases
    102968561 (RAC1)
 Endocytosis
  Lipid raft mediated endocytosis
   Arf6-dependent endocytosis
    102968561 (RAC1)
  Macropinocytosis
   Ras GTPases
    102968561 (RAC1)
 Others
  NADPH oxidases (Nox) and associated proteins
   Nox associated proteins
    102968561 (RAC1)
Exosome [BR:ptg04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   102968561 (RAC1)
  Exosomal proteins of other body fluids (saliva and urine)
   102968561 (RAC1)
  Exosomal proteins of colorectal cancer cells
   102968561 (RAC1)
  Exosomal proteins of bladder cancer cells
   102968561 (RAC1)
GTP-binding proteins [BR:ptg04031]
 Small (monomeric) G-proteins
  Rho Family
   Rac/Cdc42 [OT]
    102968561 (RAC1)
SSDB
Motif
Pfam: Ras Roc Arf GTP_EFTU CagD
Other DBs
NCBI-GeneID: 102968561
NCBI-ProteinID: XP_007081170
LinkDB
Position
Un
AA seq 188 aa
MSFFSFLRAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQEDY
DRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPIILVGTKLDLRDDKD
TIEKLKEKKLTPITYPQGLAMAKEIGAVKYLECSALTQRGLKTVFDEAIRAVLCPPPVKK
RKRKCLLL
NT seq 567 nt   +upstreamnt  +downstreamnt
atgtcgtttttctctttccttagagccgtaggtaaaacgtgcctactgatcagttacaca
accaatgcgtttcctggagaatatatccccactgtctttgacaactactctgccaatgtt
atggtggatggaaaaccggtgaatctgggcttatgggatacagctggacaagaagattat
gacagattacgtcccttatcctatccgcaaacagatgtattcttaatttgcttttctctt
gtgagtcctgcgtcatttgaaaatgttcgagcaaagtggtaccctgaagtgcgacaccac
tgtcccaacacccccatcatcttagtgggaactaaacttgacctcagggacgacaaagac
acgattgagaaactgaaggagaaaaagctgactcccatcacctacccgcagggtttggcc
atggcgaaggagatcggtgctgtaaaatacctggagtgctcggcgctcacgcagcgaggc
ctcaagacagtgtttgatgaagctattcgagcggttctctgcccccctcccgtcaagaag
aggaagagaaaatgcctgctgttgtaa

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