Panthera tigris altaica (Amur tiger): 102969961
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Entry
102969961 CDS
T02988
Symbol
ATIC
Name
(RefSeq) 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
KO
K00602
phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:
2.1.2.3
3.5.4.10
]
Organism
ptg
Panthera tigris altaica (Amur tiger)
Pathway
ptg00230
Purine metabolism
ptg00670
One carbon pool by folate
ptg01100
Metabolic pathways
ptg01523
Antifolate resistance
Module
ptg_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
ptg00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
102969961 (ATIC)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
102969961 (ATIC)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
102969961 (ATIC)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
ptg04147
]
102969961 (ATIC)
Enzymes [BR:
ptg01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.3 phosphoribosylaminoimidazolecarboxamide formyltransferase
102969961 (ATIC)
3. Hydrolases
3.5 Acting on carbon-nitrogen bonds, other than peptide bonds
3.5.4 In cyclic amidines
3.5.4.10 IMP cyclohydrolase
102969961 (ATIC)
Exosome [BR:
ptg04147
]
Exosomal proteins
Exosomal proteins of other body fluids (saliva and urine)
102969961 (ATIC)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
AICARFT_IMPCHas
MGS
Motif
Other DBs
NCBI-GeneID:
102969961
NCBI-ProteinID:
NP_001277521
UniProt:
W6FT44
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All DBs
Position
Un
AA seq
592 aa
AA seq
DB search
MAPGQLALFSVSDKTGLVEFARNLTSVGLNLIASGGTAKALRDAGLAVRDVSELTGFPEM
LGGRVKTLHPAVHAGILARNIPEDNADMARLDFDLIRVVVCNLYPFVKTVASPDVTVEQA
VEQIDIGGVTLLRAAAKNHARVTVVCEPEDYVAVCTEMQNSDSKDTSLETRRQLALKAFT
HTAQYDEAISDYFRKQYSKGISQMPLRYGMNPHQTPAQLYTLKPKLPITVLNGAPGFINL
CDALNAWQLVKELREALDLPAAASFKHVSPAGAAVGIPLSEDEARVCMVYDLYETLTPIS
TAYARARGADRMSSFGDFIALSDICDVPTAKIISREVSDGIVAPGYEDEALKILSKKKNG
SYCVLQMDPSYSPDENEVRTLFGLRLSQKRNNGVIDKSLFSNVVTKNKDLPESALRDLIV
ATIAVKYTQSNSVCYAKNGQVIGIGAGQQSRIHCTRLAGDKANYWWLRHHPQVLSMKFKT
GVKRAEISNAIDQYVTGTIGEDEDLVKWKALFEEVPELLTEAEKKEWVDKLNEVSISSDA
FFPFRDNVDRAKRSGVAYIAAPSGSAADRVVIEACDELGIILAHTNLRLFHH
NT seq
1779 nt
NT seq
+upstream
nt +downstream
nt
atggcacccggccagctcgccttatttagtgtctctgacaaaacgggcctcgtggaattt
gccagaaacctaacttctgttggtttgaatttgatcgcttctggaggaactgcaaaagct
ctcagggatgcaggtctggcagtcagagatgtctccgagctgacgggatttcctgaaatg
ttaggggggcgtgtgaaaaccttgcatcctgcagtccatgctggaatcttggctcgtaat
atcccagaagataatgctgacatggctagacttgatttcgatcttatcagggttgtcgtc
tgtaatctgtatccctttgtgaagacagtggcttctccagatgtaactgttgaacaggct
gttgagcagattgatattggtggagtaaccctcctgagagcagcagccaaaaaccacgct
cgagtaacagtagtatgtgaacctgaggactatgtggccgtttgcacagagatgcagaac
tccgacagtaaagacacctccttggagactagacgccagttagccttgaaggctttcact
catacagcacaatatgatgaagcgatttcagattacttcaggaaacagtatagtaaagga
atatctcagatgcccttgaggtatggaatgaatcctcaccaaactcctgcccagttatac
acgctgaagcccaagcttcccatcacagttctaaatggagcccccggatttataaacttg
tgtgatgctttgaatgcctggcagctggtgaaggaactcagagaagctttagaccttcct
gctgctgcctctttcaaacatgtcagcccagcaggtgctgctgttggaattccactaagt
gaagatgaggccagagtctgcatggtctatgatctgtatgaaacacttacacccatatca
actgcgtatgcaagagcaagaggggctgataggatgtcttcatttggtgactttatcgca
ttatctgatatttgtgatgtccctactgccaaaattatctccagagaggtatctgatggt
atcgtcgccccaggatatgaagatgaagctttgaaaatactctctaaaaagaaaaatggg
agctactgtgttcttcagatggacccgtcttacagtccagatgaaaacgaagttcgaact
ctctttggtcttcgtttaagtcagaagagaaataatggtgtcattgacaagtcattgttt
agcaatgttgtgaccaagaataaagatttgccagagtctgcgctcagagacctcattgta
gccaccattgctgtgaagtacacgcagtctaactccgtgtgctatgccaagaatggtcag
gttattggcattggagcaggacagcagtctcgaatacactgcacacgccttgcaggggat
aaggcgaactactggtggcttagacatcatccacaagtgctttcaatgaagtttaaaact
ggagtgaagagagcagaaatctccaatgccattgatcagtatgttactggaaccattggc
gaggatgaagatttggtaaagtggaaggcattgtttgaggaagtccctgaactgctaact
gaagcagagaagaaagaatgggttgacaaacttaatgaagtttctatcagctctgatgcc
ttctttcctttcagagataacgtagacagagctaaaaggagcggcgtggcatacatcgct
gctccttctggttctgctgccgacagagttgtgatagaggcttgtgatgaactgggaata
attctcgctcatacgaatcttcggctctttcatcactga
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