Panthera tigris altaica (Amur tiger): 102970050
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Entry
102970050 CDS
T02988
Symbol
TOP2A
Name
(RefSeq) topoisomerase (DNA) II alpha
KO
K03164
DNA topoisomerase II [EC:
5.6.2.2
]
Organism
ptg
Panthera tigris altaica (Amur tiger)
Pathway
ptg01524
Platinum drug resistance
Brite
KEGG Orthology (KO) [BR:
ptg00001
]
09160 Human Diseases
09176 Drug resistance: antineoplastic
01524 Platinum drug resistance
102970050 (TOP2A)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03032 DNA replication proteins [BR:
ptg03032
]
102970050 (TOP2A)
03036 Chromosome and associated proteins [BR:
ptg03036
]
102970050 (TOP2A)
Enzymes [BR:
ptg01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.2 Enzymes altering nucleic acid conformation
5.6.2.2 DNA topoisomerase (ATP-hydrolysing)
102970050 (TOP2A)
DNA replication proteins [BR:
ptg03032
]
Eukaryotic type
DNA Topoisomerases
102970050 (TOP2A)
Chromosome and associated proteins [BR:
ptg03036
]
Eukaryotic type
Chromosome condensation proteins
Other regulators of chromosome condensation
102970050 (TOP2A)
Centrosome formation proteins
Centriole proteins
102970050 (TOP2A)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
DNA_topoisoIV
TOPRIM_C
DNA_gyraseB
DTHCT
HATPase_c
Toprim
Microp_apicomplexa_20
Motif
Other DBs
NCBI-GeneID:
102970050
NCBI-ProteinID:
XP_007085875
UniProt:
A0A8C9KDG7
LinkDB
All DBs
Position
Un
AA seq
1534 aa
AA seq
DB search
MEVSPLQPVNENMLINKTKKNEDAKKRLSIERIYQKKTQLEHILLRPDTYIGSVELVTQQ
MWVYDEDIGINYREVTFVPGLYKIFDEILVNAADNKQRDPKMSCIKVTIDPENNLISIWN
NGKGIPVVEHKVEKMYVPALIFGQLLTSSNYDDDEKKVTGGRNGYGAKLCNIFSTKFTVE
TASREYKKMFKQTWMDNMGRAGEMELKPFNGEDYTCITFQPDLSKFKMQSLDKDIVALMV
RRAYDIAGSTKDVKVFLNGNKLPVKGFRSYVDMYLKDKVDETGNPLKIIHEQVNPRWEVC
LTMSEKGFQQISFVNSIATSKGGRHVDYIADQIVTKLVEVVKKKNKGGVAVKAHQVKNHM
WIFVNALIENPTFDSQTKENMTLQVKSFGSTCHLSEKFIKAAIGCGIVESILNWVKFKAQ
VQLNKKCSAVKHNRIKGIPKLDDANDAGGRNSNECTLILTEGDSAKTLAVSGLGVVGRDK
YGVFPLRGKILNVREASHKQIMENAEINNIIKIVGLQYKKNYEDEDSLKTLRYGKIMIMT
DQDQDGSHIKGLLINFIHHNWPSLLRHRFLEEFITPIVKVSKNKQEMAFYSLPEFEEWKS
STPNHKKWKVKYYKGLGTSTSKEAKEYFADMKRHRIQFKYSGPEDDAAISLAFSKKQIDD
RKEWLTHFMEDRRQRKLLGLPEDYLYGQTTTYLTYNDFINKELILFSNSDNERSIPSMVD
GLKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSSYHHGEMSLMMTIINLAQNFVGSNN
LNLLQPIGQFGTRLHGGKDSASPRYIFTMLSPLARLLFPPKDDHTLKFLYDDNQRVEPEW
YIPIIPMVLINGAEGIGTGWSCKIPNFDIREVVNNIRRLMDGEEPLPMLPSYKNFRGTIE
ELAPNQYVISGEVAILNSTTIEISELPIRTWTQTYKEQVLEPMLNGTEKTPPLITDYREY
HTDTTVKFVVKMTEEKLAEAERVGLHKVFKLQTSLTCNSMVLFDHVGCLKKYDTVLDILR
DFFELRLKYYGLRKEWLLGMLGAESAKLNNQARFILEKIDGKIIIENKPKKELIKVLIQR
GYDSDPVKAWKEAQQKVPDEEENEESDNENEAEKGDSVKDSGPTFNYLLDMPLWYLTKEK
KDELCKLRNEKEQELETLKRKSPSDLWKEDLAAFIEELEAVETKEKQEEQIGLPGKGGKA
KGKKIQMAEVLPSPCGKRVIPRVTIEMKAEAEKKIKKKIKSENTEGSPQEDGMELEGLKQ
RLEKKQKREPGTKTKKQTTLPFKPVKKGKKRNPWSDSESDMSSNESDFDVPPREIEPRRA
ATKTKFTVDLDSDDDFSDFDEKTQDEDFVPSDVSPVKTKTSPPVPTNKELKPQKSATSVM
DLDAGGAKDSVPPSLDSPAADFSAETEIINPVSKKKVAVKKTAAKSQSSTSTTGAKKRAA
PKGTKKEPGLNSDVSQKPDPPKTKNRRKRKPSTSDDSDSNFEKMISKTVTSKKSKGESED
FHLDLDSAVAPRAKSGRAKKPIKYLEESDEDDLF
NT seq
4605 nt
NT seq
+upstream
nt +downstream
nt
atggaggtgtcaccactgcagcctgtaaatgaaaatatgctaatcaacaaaacaaagaaa
aatgaagatgctaagaaaagactgtctattgaaaggatctatcaaaagaaaacccaactg
gaacatattttgctccgcccagacacctatattggctccgtggaattagtgacccagcaa
atgtgggtttacgatgaagatattggcattaactacagggaagtcacctttgtccctggg
ttgtacaaaatctttgatgagattctagtcaatgctgcagacaacaaacaaagggaccca
aaaatgtcttgtattaaagtcacaattgacccggaaaacaatttaattagtatatggaat
aatgggaaaggtattcctgttgttgaacacaaagttgagaagatgtatgtcccagctctc
atctttggacagctcctaacttctagtaactatgatgatgatgaaaagaaagtaacaggt
ggtcgaaatggctatggggccaaattgtgtaacatattcagtaccaaatttactgtggaa
acagccagtagagaatacaagaaaatgttcaaacagacgtggatggataacatgggaagg
gctggtgagatggaactcaagcccttcaatggggaagattatacatgtattaccttccag
cctgatttgtccaagtttaaaatgcaaagcctagacaaagatattgttgcactaatggtc
agaagagcatatgatattgccggatccactaaagatgtcaaagtgtttctcaatggaaat
aagctgccagtaaaaggattccgtagctatgtagatatgtatttgaaggataaggtagat
gaaactggcaatccgttgaaaattatccatgaacaagtaaaccccaggtgggaagtatgc
ttaacaatgagtgaaaaaggctttcagcaaattagctttgtcaacagcattgctacttcc
aagggtggcagacatgttgattatatagctgatcagattgtgactaaacttgttgaggtt
gttaaaaagaagaacaagggtggtgttgcagtaaaagcacatcaggtgaaaaatcacatg
tggatttttgtgaatgccttaattgaaaacccaacctttgattctcagacaaaagagaac
atgactttacaagtcaagagctttggatcaacctgccatttaagtgaaaaattcatcaaa
gctgcaattggttgtggtattgtagaaagcatactaaactgggtgaagtttaaggcccaa
gtacagttaaacaagaagtgttcagctgtaaaacataacaggatcaagggaattcccaaa
ctcgatgatgccaatgatgcagggggtcgaaattccaatgagtgtacacttatcctgact
gagggagactcagctaaaactttggctgtttcgggccttggcgtggttgggagagacaaa
tatggggttttcccgcttagaggaaaaatactcaatgttcgagaagcttctcataaacag
atcatggaaaatgctgaaattaacaatatcatcaagattgtgggtcttcagtacaagaaa
aactatgaagatgaagattcattgaagactcttcgttatgggaagataatgattatgaca
gatcaggaccaagatggttcccatatcaaaggcttgctgattaattttatccatcacaac
tggccctctcttctgcggcaccgttttctggaagaatttatcactcctattgtaaaggtg
tctaaaaacaagcaagaaatggcattctatagccttcctgaatttgaagaatggaagagt
tctacaccaaatcataaaaaatggaaagtcaagtactacaaaggtttgggcacgagcaca
tcaaaagaggctaaggaatactttgcagatatgaaaagacatcgtattcaattcaaatat
tccggtcctgaagatgatgctgccatcagcctggcctttagcaagaaacagatagatgat
cgaaaggaatggttaactcatttcatggaggacagaaggcaacggaagttacttggcctt
cctgaggattacttgtatggacaaactaccacatatctgacatataatgacttcataaac
aaggaacttatcctgttctcaaattctgataacgagagatctattccatctatggtggat
ggtttgaaaccaggtcaaagaaaggttttgtttacctgtttcaaacggaatgacaagcga
gaggtgaaggttgctcagttagctgggtcagtggcagagatgtcctcttatcatcatggt
gagatgtcactaatgatgaccattatcaatttggctcagaattttgtgggtagcaataat
ctgaacctcttgcaacccattggtcagtttggtaccaggctgcatggtggtaaggattct
gctagtcctcgatacatcttcacaatgctcagccctttggctcggttgttatttccacca
aaagatgatcatacattaaagtttttatatgatgacaatcaacgtgttgaacctgaatgg
tacattcctattatacccatggtgctgataaatggtgctgaaggaatcggtactgggtgg
tcctgcaaaatcccgaactttgatattcgtgaagttgtaaataatatcaggcgtctgatg
gatggagaagaacctttgccaatgcttccgagttacaagaacttcaggggtacgattgaa
gagctggctccaaatcaatatgtgattagtggtgaagtggctattcttaattccacaacc
attgaaatctcagaacttcccatcagaacatggacccaaacatataaagaacaggttcta
gaacccatgttgaatggcactgagaagacaccacctctcataaccgattatagggaatac
catacagacaccactgtgaagtttgttgtgaagatgactgaagagaaattggcagaggca
gagagagtgggactacacaaagtcttcaaactccagactagtctcacatgcaactctatg
gtgctttttgaccatgtaggatgtttaaagaaatatgacacagtgttggatattctaaga
gacttctttgaactcaggcttaagtattatggattaagaaaagaatggctactaggaatg
cttggtgctgaatctgctaaactgaacaatcaggctcgctttatcttagagaaaatagat
ggcaaaataatcattgaaaataagccaaagaaggaattaattaaagttctgattcagagg
ggttatgattctgatcctgtgaaggcttggaaagaagcccagcaaaaggtaccagatgaa
gaagaaaatgaagagagtgacaatgaaaatgaagccgaaaagggtgactctgtaaaagat
tctggaccaaccttcaactaccttcttgatatgcctctttggtatctcaccaaggaaaag
aaggatgaactgtgcaagctgagaaatgaaaaagaacaagagctagaaacattaaagaga
aagagtccatcagatttgtggaaagaagacctagctgcttttattgaagagctggaggct
gttgaaacaaaggaaaaacaagaagaacaaataggactccctgggaaaggggggaaagca
aaggggaaaaaaatacagatggctgaagttttgccttctccatgtgggaaaagagtcatc
ccccgagtgaccatagagatgaaagcagaggcagaaaagaaaattaaaaagaaaattaag
agtgaaaacactgaagggagccctcaagaggatggtatggaactagaaggtctgaaacaa
aggttggagaagaaacagaaaagagagccaggtaccaagacaaagaagcaaactacgttg
ccatttaaaccagtcaaaaaaggaaagaagagaaacccctggtctgattcagaatcagat
atgagcagtaatgaaagtgactttgatgttcccccacgagagatagagccacggagagca
gcaacaaaaaccaaatttacagtggatttggattcagatgatgatttctcagattttgat
gaaaaaactcaagatgaggattttgtcccatcagatgttagcccagttaagaccaaaact
tccccaccagtacctactaacaaagaactgaagccacagaagagtgccacatcagtaatg
gaccttgatgctggtggtgccaaggacagtgtaccaccttctctagattctccggccgct
gatttctcagctgaaactgaaatcataaaccctgtttctaaaaagaaggtagcggtgaag
aagacagcagcaaaaagtcagtcttccacctccactacaggtgccaaaaaaagggctgca
ccaaaaggaaccaaaaaggagccaggcttgaattctgatgtctctcaaaagcctgatcct
cccaaaaccaaaaatcgccgcaaaaggaagccatccacttctgatgattctgactctaat
tttgagaaaatgatttctaagacagtcacaagcaagaaatccaagggggagagtgaggat
ttccatctggacttagactcagctgtggctcctcgggccaaatctggacgggcaaagaaa
cctataaagtacctcgaagaatcagatgaagatgatctgttctaa
DBGET
integrated database retrieval system
