Panthera tigris altaica (Amur tiger): 102972917 Help Entry 102972917         CDS       T02988                                  Symbol ADCY7 Name (RefSeq) adenylate cyclase 7   KO K08047   adenylate cyclase 7 [EC:4.6.1.1] Organism ptg  Panthera tigris altaica (Amur tiger) Pathway ptg00230   Purine metabolism ptg01100   Metabolic pathways ptg01522   Endocrine resistance ptg04015   Rap1 signaling pathway ptg04020   Calcium signaling pathway ptg04022   cGMP-PKG signaling pathway ptg04024   cAMP signaling pathway ptg04062   Chemokine signaling pathway ptg04072   Phospholipase D signaling pathway ptg04081   Hormone signaling ptg04082   Neuroactive ligand signaling ptg04114   Oocyte meiosis ptg04211   Longevity regulating pathway ptg04213   Longevity regulating pathway - multiple species ptg04261   Adrenergic signaling in cardiomyocytes ptg04270   Vascular smooth muscle contraction ptg04371   Apelin signaling pathway ptg04540   Gap junction ptg04611   Platelet activation ptg04713   Circadian entrainment ptg04714   Thermogenesis ptg04723   Retrograde endocannabinoid signaling ptg04724   Glutamatergic synapse ptg04725   Cholinergic synapse ptg04727   GABAergic synapse ptg04750   Inflammatory mediator regulation of TRP channels ptg04911   Insulin secretion ptg04912   GnRH signaling pathway ptg04913   Ovarian steroidogenesis ptg04914   Progesterone-mediated oocyte maturation ptg04915   Estrogen signaling pathway ptg04916   Melanogenesis ptg04918   Thyroid hormone synthesis ptg04921   Oxytocin signaling pathway ptg04923   Regulation of lipolysis in adipocytes ptg04925   Aldosterone synthesis and secretion ptg04926   Relaxin signaling pathway ptg04927   Cortisol synthesis and secretion ptg04928   Parathyroid hormone synthesis, secretion and action ptg04934   Cushing syndrome ptg04935   Growth hormone synthesis, secretion and action ptg04970   Salivary secretion ptg04971   Gastric acid secretion ptg04972   Pancreatic secretion ptg04976   Bile secretion ptg05032   Morphine addiction ptg05163   Human cytomegalovirus infection ptg05166   Human T-cell leukemia virus 1 infection ptg05200   Pathways in cancer ptg05207   Chemical carcinogenesis - receptor activation ptg05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:ptg00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     102972917 (ADCY7)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     102972917 (ADCY7)    04371 Apelin signaling pathway     102972917 (ADCY7)    04020 Calcium signaling pathway     102972917 (ADCY7)    04072 Phospholipase D signaling pathway     102972917 (ADCY7)    04024 cAMP signaling pathway     102972917 (ADCY7)    04022 cGMP-PKG signaling pathway     102972917 (ADCY7)   09133 Signaling molecules and interaction    04082 Neuroactive ligand signaling     102972917 (ADCY7)    04081 Hormone signaling     102972917 (ADCY7)  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     102972917 (ADCY7)   09144 Cellular community - eukaryotes    04540 Gap junction     102972917 (ADCY7)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     102972917 (ADCY7)    04062 Chemokine signaling pathway     102972917 (ADCY7)   09152 Endocrine system    04911 Insulin secretion     102972917 (ADCY7)    04923 Regulation of lipolysis in adipocytes     102972917 (ADCY7)    04912 GnRH signaling pathway     102972917 (ADCY7)    04913 Ovarian steroidogenesis     102972917 (ADCY7)    04915 Estrogen signaling pathway     102972917 (ADCY7)    04914 Progesterone-mediated oocyte maturation     102972917 (ADCY7)    04921 Oxytocin signaling pathway     102972917 (ADCY7)    04926 Relaxin signaling pathway     102972917 (ADCY7)    04935 Growth hormone synthesis, secretion and action     102972917 (ADCY7)    04918 Thyroid hormone synthesis     102972917 (ADCY7)    04928 Parathyroid hormone synthesis, secretion and action     102972917 (ADCY7)    04916 Melanogenesis     102972917 (ADCY7)    04925 Aldosterone synthesis and secretion     102972917 (ADCY7)    04927 Cortisol synthesis and secretion     102972917 (ADCY7)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     102972917 (ADCY7)    04270 Vascular smooth muscle contraction     102972917 (ADCY7)   09154 Digestive system    04970 Salivary secretion     102972917 (ADCY7)    04971 Gastric acid secretion     102972917 (ADCY7)    04972 Pancreatic secretion     102972917 (ADCY7)    04976 Bile secretion     102972917 (ADCY7)   09156 Nervous system    04724 Glutamatergic synapse     102972917 (ADCY7)    04727 GABAergic synapse     102972917 (ADCY7)    04725 Cholinergic synapse     102972917 (ADCY7)    04723 Retrograde endocannabinoid signaling     102972917 (ADCY7)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     102972917 (ADCY7)   09149 Aging    04211 Longevity regulating pathway     102972917 (ADCY7)    04213 Longevity regulating pathway - multiple species     102972917 (ADCY7)   09159 Environmental adaptation    04713 Circadian entrainment     102972917 (ADCY7)    04714 Thermogenesis     102972917 (ADCY7)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     102972917 (ADCY7)    05207 Chemical carcinogenesis - receptor activation     102972917 (ADCY7)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     102972917 (ADCY7)    05163 Human cytomegalovirus infection     102972917 (ADCY7)   09165 Substance dependence    05032 Morphine addiction     102972917 (ADCY7)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     102972917 (ADCY7)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     102972917 (ADCY7)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     102972917 (ADCY7) Enzymes [BR:ptg01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      102972917 (ADCY7) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Guanylate_cyc Adcy_cons_dom AC_N Motif Other DBs NCBI-GeneID:  102972917 NCBI-ProteinID:  XP_015399531 LinkDB All DBs Position Un AA seq 1112 aa AA seqDB search MVVKATLAKTAQSPKVRKSLVFRWSIDVTRVENTGISVYVCPAQDPSGHQTVLGTTFFTL AVFVVLYVLVYVECLVRRWLRASALLIWVCLMMLGYVLVFDSWIKTTHMGAQVPFFLFIV FVVYTLLPFSMQGAVVAGAVSSISHLLVIGALMEAFTTPSVRAGLQLLANAVIFLCGNLT GAFHKHQMQDASRDLFTYTVKCIQIRRKLRIKKRQQENLLLSVLPAHISMGMKLAIIERL KERGDRRYMPDNNFHSLYVKRHQNVSILYADIVGFTRLASDCSPKELVVMLNELFGKFDQ IAKANECMRIKILGDCYYCVSGLPVSLPTHARNCVKMGLDMCEAIKQVREATGVDISMRV GIHSGNVLCGVIGLRKWQYDVWSHDVSLANRMEAAGVPGQVHITEATLNHLDKAYEVEDG HGQQRDPHLKEMNIHTYLVIDPRSQQPPPPSQHLPKPKGDVALKMRASVRMTRYLESWGA ARPFAHLNHRESVSSNETPIPNGRRPKAIPLRRHRAPDRSASPKGRSEDDSYDEEILSAI EGLSSTRPCCSKSDDFYTFGSIFLEKGFEREYRLAPIPRVRHYFACASLVFVCILLVHVL LLPRMAALGVSFGLVACVLGLVLGLCFAHEFLVSGKARAGTWPGPAPPALPLPPPFPGAL RAQLRPFCLDDSLPGASPSHLPSQAAAGPQVAVAVPGPKGGNVPSVCAPHDPLRRLSLAI LTIGSLLSIAIVNLPLMPFPALRQPAGNQSLADGDVSSRELAPCKLLPVSAAGLLGTACP HLDRSRTAREVEDFAVAILGHPGVSCGVAALFPFVSSSSPFCLWKDPKAMINFYLVLFYV TLIMLSRQIDYYCRLDCLWKKKFKKEHEEFETMENVNRLLLENVLPAHVAAHFIGDKLNE DWYHQSYDCVCVMFASVPDFKVFYTECDVNKEGLECLRLLNEIISDFDELLLKPKFSSVE KIKTIGSTYMAAVGLSVPSGTENQDLERQHAHIGIMVEFSIALMSKLDGINRHSFNSFRL RVGINHGPVIAGVIGARKPQYDIWGNTVNVASRMESTGELGKIQVTEETCTILQGLGYSC ECRGLINVKGKGELRTYFVCTDTAKFQGSGLN NT seq 3339 nt NT seq  +upstreamnt  +downstreamnt atggtggtgaaggcaaccttagccaagacagcacaaagcccaaaggtaaggaagagcttg gtgttcagatggagcatagatgtcacccgtgtggagaacacaggcatttccgtgtatgtt tgccctgcccaggacccctctggacaccagactgtcctggggacgaccttcttcacactt gctgtgtttgtggttctctacgtgctggtttatgttgagtgcctcgtccggcggtggctc agggcctcggcgctgctcatctgggtctgccttatgatgctgggctatgtgctggtgttc gactcatggataaagacaacccacatgggggcacaggtgcccttcttcctcttcatcgtg ttcgtggtgtacacgctgctgcccttcagcatgcagggggccgtcgtggcgggggcagtc tccagcatctcccacctcctcgtgatcggggctctgatggaggccttcacgacacccagt gtccgtgcagggctgcagctgctggccaacgctgtcatcttcctgtgtgggaatctcacg ggcgccttccacaagcaccagatgcaggacgcctcccgagacctcttcacctataccgtc aagtgcatccagatccgtcgtaaactgcgcatcaagaagcgtcagcaggagaacctgctg ctgtcggtgctgcccgcccacatctccatgggcatgaagctggccatcatcgagcggctc aaggagcgcggggaccgccgctacatgcccgacaacaacttccacagcctgtacgtcaag cggcaccagaacgtcagcatcctctatgcggacatcgtgggcttcacgcggctggccagc gactgctcccccaaagagttggtggtgatgctgaacgagctcttcggcaagttcgaccag atcgccaaggccaatgagtgtatgcggatcaagatcctgggcgactgctattactgtgtg tcgggcctgcccgtatccctgcccacccatgcccggaactgtgtgaagatggggctggac atgtgtgaggccattaagcaggtgcgagaggccacaggtgtggacatcagcatgcgtgtg ggcatccactcagggaacgtgctgtgtggtgtcattgggctgcgcaagtggcagtacgac gtgtggtcccacgacgtgtctctggccaacaggatggaggcggctggagtccctgggcag gtgcacatcacagaggccacgctgaaccacctggacaaggcgtatgaggtggaggacggg cacgggcagcagcgggacccccacctgaaggagatgaacatccacacctacctggtcatc gacccccggagccagcagccgcccccgcccagccagcacctccccaagcccaagggggat gtggccctgaagatgcgggcgtccgtgcgcatgacccgctacctcgagtcctggggggcc gcacggccctttgcacacctcaaccaccgcgagagcgtgagcagcaacgagacccctatc cccaacggacggaggcccaaggccattcccctgcggcgccaccgggcccctgacaggagt gcatcccccaaggggaggtctgaggacgactcatacgacgaggagatcctctcggccatc gaggggcttagctccacgaggccctgctgctccaagtctgatgacttctacacctttggg tccatcttcctggagaagggctttgagcgagagtaccgcctggcgcccatcccccgggtc cgccactatttcgcctgcgccagcctcgtcttcgtctgcatcctgctcgttcacgtcctg ctcttgcccaggatggcggccctgggtgtgtccttcgggctggtggcctgtgtgctgggg ctggtgctgggcctgtgctttgcccacgagttcctggtgagtgggaaagcccgagcgggc acctggccgggccctgcccccccggccctcccgctgcctccacccttccccggagccctc cgtgctcaacttcgccccttctgcctggatgacagtttgccgggcgcttctcccagtcat ctgccctcccaggctgctgctggcccccaagtggctgtggccgtccccggcccgaagggt gggaacgtcccttctgtctgtgcaccccatgaccccttgcggcgcctgtccctggccatc ctgaccattggcagcctgctcagcatcgccatcgtcaacctgccgctgatgcctttcccg gccctgaggcagcctgcaggcaaccagagcttggcggatggggacgtgagcagcagggag ctggccccgtgcaagctcctcccggtgagtgcggccggacttctgggcaccgcgtgtccc cacctggaccgctcccgcacagctcgagaggttgaagactttgccgtggctatccttggt catccgggtgtgagctgtggtgtcgccgcgctttttcccttcgtgtccagcagctccccg ttctgtctgtggaaggacccgaaggcaatgatcaatttctacctggttttgttttacgtc accctcatcatgctctccagacagattgactattactgccgcttggattgcttgtggaag aagaagttcaaaaaggaacacgaggagtttgaaaccatggagaacgtgaaccgcctcctt ctggagaacgtcttgccagcccacgtggccgcacacttcattggtgacaagctaaatgag gactggtaccatcagtcctacgactgtgtgtgtgtcatgtttgcgtcggtgccggacttc aaagtcttctacacggagtgcgatgtcaacaaggaggggctggagtgcctgcgtctgctg aacgagatcatctccgacttcgacgagctgctcctaaagcccaagttcagcagtgtggag aagatcaagaccattggcagcacgtacatggcagccgtggggctcagcgtcccctcaggg actgagaaccaggacctggaacggcagcacgcgcacatcggcatcatggtggagttcagc atcgccctgatgagcaagctggacggcatcaaccggcactccttcaactccttccgcctg cgagtcggcataaaccacgggcctgtgatcgctggagtgatcggggcacgaaagcctcag tatgatatctggggaaacacggtcaatgtcgccagccgaatggagagcactggagaactt ggcaagatccaggttactgaggagacatgcaccatcctccagggactaggttattcttgc gagtgccggggactgattaacgtcaaaggcaaaggcgagctgaggacttactttgtctgc acagacacggcaaagttccaagggtcgggactgaattga

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