Pelotomaculum thermopropionicum: PTH_0535
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Entry
PTH_0535 CDS
T00519
Symbol
LeuA
Name
(GenBank) isopropylmalate/homocitrate/citramalate synthases
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
pth
Pelotomaculum thermopropionicum
Pathway
pth00290
Valine, leucine and isoleucine biosynthesis
pth00620
Pyruvate metabolism
pth01100
Metabolic pathways
pth01110
Biosynthesis of secondary metabolites
pth01210
2-Oxocarboxylic acid metabolism
pth01230
Biosynthesis of amino acids
Module
pth_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
pth00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
PTH_0535 (LeuA)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
PTH_0535 (LeuA)
Enzymes [BR:
pth01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
PTH_0535 (LeuA)
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Motif
Pfam:
HMGL-like
LeuA_dimer
HCS_D2
PEP_mutase
Asparaginase_C
Motif
Other DBs
NCBI-ProteinID:
BAF58716
UniProt:
A5D4W4
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All DBs
Position
527216..528856
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AA seq
546 aa
AA seq
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MPSVKIYDTTLRDGAQAEGISFSVEDKIKIALRLDKMGFHYIEGGWPGSNPKDLEFFKKI
RHCPLRHARLAAFGSTRKAGAAAENDASVKAIIDSGVQVATIFGKSWDFHVFKALGVTLE
ENLAMIRETVAYLKSRGLEVIYDAEHFFDGCKANPAYALETIRAAAESGASAVVLCDTNG
GTLPAEVKELVEKARSVLGVPVGIHAHNDGELAVANTLAAVQAGAEQVQGTVNGYGERCG
NANLCSVIPNLTLKCGIETIPREKLVHLTDLSHFVSEVANISPNPHQPFVGASAFAHKGG
VHVSALLKDSRTYEHISPGEVGNRRRVLVSELSGMSNLLYKYKELNLDIERQSPEGKRIL
EDIKKLESQGFQFEDAEGSFELLVRKTNHGYRDPFILEALRLLVEIKENTPAYSEAIIKM
RVGDRVVHTAAEGNGPVNALDNALRKALYDFYPCIGSMHLTDYKVRVLEEKDGTGAAVRV
HIQTGDGKRSWGTVGVSRNIIEASWQALADSISYGLLKGDHLARNGEEEKAVNGKKPAGN
GSLQTN
NT seq
1641 nt
NT seq
+upstream
nt +downstream
nt
atgccatcggtgaaaatatacgatactacccttcgcgacggggcacaggcagaaggcatt
tccttctccgtggaggataaaataaaaattgccttgcgcctggacaaaatgggctttcat
tatattgagggcgggtggcccggctccaaccccaaggatctggagttttttaaaaaaatc
cggcattgccctttaaggcatgccaggctggccgctttcggttcaacccgcaaggccgga
gctgcggccgaaaacgacgccagcgtaaaggccattattgattccggcgtgcaggtggcc
acgatattcggcaagtcatgggatttccacgtctttaaggctctgggggttaccctggag
gaaaacctggccatgatcagggagaccgtggcttacctgaaaagccggggacttgaggta
atctacgacgccgagcactttttcgacggctgcaaggccaacccggcctatgccctggaa
accatcagggcggcggcagaaagcggcgcctccgcggtggttttatgcgacaccaacgga
ggcaccctgcccgccgaagttaaagaactggtggagaaggccaggagcgtgctgggcgtt
cccgttggcatccacgcccataatgacggcgagctggccgtggccaacacgctggccgcc
gtgcaggccggcgcggagcaggtgcagggcacggtgaacggctacggcgagaggtgcggc
aacgccaatctctgttcggttattcccaatctcaccctgaaatgcggcattgaaaccata
cccagggaaaaactggtccaccttaccgacctgtcccactttgtcagcgaggtggccaac
ataagcccgaatccccaccagcctttcgtcggggccagcgcctttgcgcacaagggcggg
gtgcatgtgagcgccctcttaaaggactccaggacgtatgaacacatatcccccggggag
gttgggaaccgccgcagggtgctggtgtcggagctttcgggaatgtccaaccttttgtac
aagtacaaggaactgaatctcgatatagaaaggcagagcccggaagggaagcgcatcctg
gaagacattaaaaagctggagagccaggggtttcagttcgaggacgcggaaggttccttc
gagctgctggtgcgcaagaccaaccacggctaccgcgatccgttcattcttgaggctctg
cgcctgctggtggagataaaggaaaacacccctgcctattctgaggcaattatcaagatg
cgggtgggagaccgggtggtgcacaccgcggccgaaggcaacgggccggtaaacgccctg
gacaacgccctgcgcaaggcgctgtacgacttttacccctgcatcgggtcgatgcacctc
accgactacaaggtgcgcgtcctggaagaaaaggacggcaccggagcggcggtaagggtg
cacattcaaaccggcgatgggaagcgttcctggggtaccgtgggcgtgtcccggaacatc
atcgaagcaagctggcaggccctggcggacagcatttcttacggcctgctgaaaggcgat
catcttgcccggaatggcgaggaggaaaaagccgtaaacggcaaaaagccggcaggaaac
ggcagtttgcagacgaattaa
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