Pelotomaculum thermopropionicum: PTH_1865
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Entry
PTH_1865 CDS
T00519
Symbol
MurF
Name
(GenBank) UDP-N-acetylmuramyl pentapeptide synthase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
pth
Pelotomaculum thermopropionicum
Pathway
pth00300
Lysine biosynthesis
pth00550
Peptidoglycan biosynthesis
pth01100
Metabolic pathways
pth01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
pth00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
PTH_1865 (MurF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
PTH_1865 (MurF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
PTH_1865 (MurF)
Enzymes [BR:
pth01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
PTH_1865 (MurF)
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
BAF60046
UniProt:
A5D149
LinkDB
All DBs
Position
complement(1950440..1951849)
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AA seq
469 aa
AA seq
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MKPVTLKELERIACGRIIQGDPGTVLSSVSTDTRRLKKGEIFFALSGERHDAHNFLAQAA
GAGAGCLVVSRTADLPAGVPVLAVENTLAALQALAAFNRKSCGARVVAVTGSTGKTTTKD
MTASILSTRLRTLKSEGNFNNEIGLPLTLLRLDETCEIAVVEMAMRGAGEIDALCRIAKP
DCAVITNIGEAHLELLGTVSNIAAAKGEVLEHIPAGGFALLNAEAPFIRREAGRCRGKVI
YYGIDCPADIRAANIRPEGRGSRFEVILDGERREFFLPVPGRHNVMNALAAIGVARELGL
TWEEVARGLAAVTLTGMRLEIIEAKNLRIINDAYNANPASAKAALQVLKEMAGGRRAVAV
LGNMLELGPRAAEGHREVGEAAAGARVSCLVTVGDLAAGIAEGALDAGLPAERIFRCADN
MQAAGILEELIRDGDVVLVKGSRGMKMEEIVRCLLKSREPALLQEAGPG
NT seq
1410 nt
NT seq
+upstream
nt +downstream
nt
atgaaaccggttactttgaaagaactcgagagaattgcctgtgggagaattatccaggga
gaccccggaactgttttaagctcggtgtccaccgacacccgcaggctcaaaaaaggagag
attttttttgccctgtccggggagcggcatgacgcccataactttctggcgcaggccgcc
ggggcaggggcaggctgcctggtggtgagccgtaccgcggatttgcctgcgggagtgccc
gttctggcggttgagaacaccctggctgcgctgcaggctctggcagccttcaacaggaaa
agctgcggggcgcgtgtggtggcggttaccggcagcaccggaaaaactaccacaaaggat
atgacagccagcattttaagcacccgcctgcgcactttaaaaagtgaaggcaatttcaat
aatgaaatcggccttcccctgaccctgctcaggctggacgaaacgtgcgaaatagccgta
gttgagatggccatgcggggagcgggggagattgatgccttgtgccggattgccaaaccg
gactgtgctgtaattacaaatatcggggaggcccatctggagcttttgggcacggtaagc
aatatagccgccgccaaaggagaggtgctggaacacatacccgccggcgggtttgccctg
ctgaatgccgaggccccgtttatcaggcgggaggcggggcgttgccggggcaaggtgatc
tattacggcatcgactgtcctgccgacataagggcggcaaacataaggcccgagggccgg
gggagccgctttgaagttatcctggacggtgaaaggcgggaatttttccttcctgttccc
ggccgtcacaacgtgatgaatgccctggccgccataggcgtggcaagggaactgggatta
acttgggaggaagtggccaggggactggctgcggtcacgttgaccggaatgcgcctggag
ataattgaggccaaaaacttaagaatcatcaacgatgcttataatgccaaccccgcttct
gccaaagcggcattgcaggttttaaaggaaatggccggcgggcggcgcgccgtggccgtg
ctgggcaatatgctggaactcggtccgcgcgctgcggaagggcaccgggaagtgggggag
gccgcagccggggcaagggtatcctgcctggttacggttggagacctggctgcgggaatt
gccgaaggggcattagacgccgggctgcctgcggagaggatttttcggtgcgctgacaac
atgcaggccgcaggtatactagaggaactgataagggacggcgatgtggtgctggttaaa
ggatccaggggaatgaaaatggaggaaatcgtcaggtgcctgctgaaatccagggagccc
gcgcttttgcaggaggcaggccccggttaa
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