Providencia stuartii 2017-45-35: OI982_16215
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Entry
OI982_16215 CDS
T09168
Symbol
thrA
Name
(GenBank) bifunctional aspartate kinase/homoserine dehydrogenase I
KO
K12524
bifunctional aspartokinase / homoserine dehydrogenase 1 [EC:
2.7.2.4
1.1.1.3
]
Organism
ptha
Providencia stuartii 2017-45-35
Pathway
ptha00260
Glycine, serine and threonine metabolism
ptha00261
Monobactam biosynthesis
ptha00270
Cysteine and methionine metabolism
ptha00300
Lysine biosynthesis
ptha01100
Metabolic pathways
ptha01110
Biosynthesis of secondary metabolites
ptha01120
Microbial metabolism in diverse environments
ptha01230
Biosynthesis of amino acids
Module
ptha_M00016
Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine
ptha_M00017
Methionine biosynthesis, aspartate => homoserine => methionine
ptha_M00018
Threonine biosynthesis, aspartate => homoserine => threonine
ptha_M00526
Lysine biosynthesis, DAP dehydrogenase pathway, aspartate => lysine
Brite
KEGG Orthology (KO) [BR:
ptha00001
]
09100 Metabolism
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
OI982_16215 (thrA)
00270 Cysteine and methionine metabolism
OI982_16215 (thrA)
00300 Lysine biosynthesis
OI982_16215 (thrA)
09110 Biosynthesis of other secondary metabolites
00261 Monobactam biosynthesis
OI982_16215 (thrA)
Enzymes [BR:
ptha01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.3 homoserine dehydrogenase
OI982_16215 (thrA)
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.2 Phosphotransferases with a carboxy group as acceptor
2.7.2.4 aspartate kinase
OI982_16215 (thrA)
BRITE hierarchy
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Paralog
Gene cluster
GFIT
Motif
Pfam:
Homoserine_dh
AA_kinase
ACT_9
NAD_binding_3
ACT_7
ACT
Motif
Other DBs
NCBI-ProteinID:
WIJ73012
LinkDB
All DBs
Position
3394249..3396708
Genome browser
AA seq
819 aa
AA seq
DB search
MRVLKFGGTSVANDERVLNVADIAESKLADGQVALVLSAPAKITNHLVAMIDKTVAGQDV
ITHVNDAEMIFANLLKGLKEKQPGFDYDRLKKLTEQEFAQIKQVLHGITLLGQCPDSINA
SIICRGEKLSIAIMESVLTARGHKVTVINPVENLLAVGHYLESTVDINESTKRIKELNIP
KDHFVLMAGFTAGNDKGELVVLGRNGSDYSAAVLAACLRAECCEIWTDVDGVYTCDPRLV
PDARLLKGMSYQEAMELSYFGAKVLHPRTIAPIAQFQIPCLIKNTTNLSAPGTLIGDGQT
DDSTPVKGITNLNNMAMINVSGPGMKGMVGMAARIFSVMSRKGISVVLITQSSSEYSISF
CVPQGELVRARAALEEEFYLELKDGVLDPLDVMEQLAIISVVGDGMRTLKGISARFFSAL
TRGNINIVAIAQGSSERSISAVIANEAATTAVRLCHQMLFNAEQVIEAFIIGVGGVGNAL
IEQIHRQQQWLKQKHIDLRVCGIANSRAMLTNMQGISLDNWKEELAQATEPFSLSRLIRL
EREYHFLNPVIIDCTSNQEIAQQYVSFLKDGFNVVTPNKKANTLSMEYYRQLRSACEVSK
RKFLYDTNVGAGLPVIENLQNLLNAGDELVHFSGILSGSLSFIFGKLDEGMSLSEATALA
KEKGFTEPDPRDDLSGMDVARKLLILAREAGYELELEDIEIEPVLPAEFDSSGDVTEFMA
RLPQLDQPFAERIKAAEAEEKVLRYVGLIEEGRCQVKIVAVDGNDPLFKVKNGENALAFY
TRYYQPIPLVLRGYGAGNDVTAAGVFADMLRTLSWKLGV
NT seq
2460 nt
NT seq
+upstream
nt +downstream
nt
atgcgtgtgcttaaatttggcggtacttcggttgcaaatgacgaacgagtactgaatgtt
gctgacatcgctgaaagtaaattggccgatgggcaagtggcgttggtgctatctgcacca
gcaaaaatcactaaccatttggtcgcaatgattgataaaacggttgcaggtcaggatgtc
atcacgcatgtgaatgatgcagaaatgatttttgcgaacttattaaaaggattaaaagaa
aaacaacccggttttgattacgatagactgaaaaaactcactgaacaagaattcgcacaa
atcaaacaagtactgcatggtattactcttctaggccaatgccctgatagcattaacgcc
tcaattatttgccgtggtgaaaaactctctattgccattatggagtctgtgctaacagca
cgcgggcacaaagtcacggtgattaatcctgtcgaaaatttattagccgtcggtcattat
cttgagtccactgttgatattaatgagtcaactaaacgtattaaggaattaaacatccct
aaagaccactttgtattaatggcgggttttactgcggggaatgataaaggcgaattggtc
gtattagggcgtaacggctccgattattccgcggcagtattagcggcttgtttacgtgct
gaatgctgcgaaatttggaccgatgtggatggggtatatacttgtgacccacgtttagtg
cctgatgcacgcctattaaaagggatgtcctatcaagaggcgatggagttatcctacttt
ggtgcaaaagtactgcacccgcgtaccatagcaccaatcgcacaattccaaattccttgc
cttatcaaaaacaccactaacctcagtgctccgggtacattgatcggggatggacaaaca
gatgacagcactcctgttaaagggatcaccaacctgaataacatggcgatgatcaacgtt
tcaggccccggcatgaaaggaatggttggtatggccgcacgtatcttctctgtgatgtca
cgtaaggggatctcggttgtacttattacgcagtcatcatcggaatacagcattagcttc
tgtgtgcctcaaggggaattagtacgtgcacgtgctgccttggaagaagaattctattta
gaattaaaagatggcgtcttagaccctcttgatgtcatggagcagttagccattatttcg
gtcgttggcgacggcatgcgtactctaaaagggatttcagcgcgtttcttctcggcatta
acacgcggtaatatcaatatcgtggcgattgcccaaggttcgtctgaacgttcaatttcg
gcggtcattgccaatgaagcagcaaccacggcggttcgtttatgccatcaaatgctattc
aatgctgagcaagtcattgaagccttcattatcggtgtgggtggggtaggaaacgcactg
attgagcaaatccatcgtcaacagcaatggctgaaacaaaagcatatcgatttacgcgtt
tgtgggatcgccaactcacgagcaatgttgacgaatatgcaaggcatctctcttgataat
tggaaagaagagttggcgcaagcgaccgagccatttagcctgagccgcttgatcagattg
gagcgtgaatatcactttctcaatccagtgatcatcgattgtacttctaaccaagaaatt
gcccagcagtatgtcagtttcttaaaagacggctttaacgttgtgacacctaacaaaaaa
gctaacaccttatcaatggagtattaccgccaattacgctccgcgtgtgaagtatcaaaa
cgtaagttcctttatgacactaacgttggtgcggggttgcctgtgattgaaaacttacag
aatctcctgaatgcgggtgatgagctagttcactttagcggtattctttctggatcactc
tcctttatttttggcaaactcgacgaagggatgtctttatctgaagcgacggctctagct
aaagagaaagggtttaccgagccagatcctcgcgatgatttgtcaggcatggatgtcgca
cgtaagctgttgatcctcgcgcgtgaagccggttatgaattagagctagaagatattgaa
atcgaacccgtattacctgcggagtttgatagcagtggcgatgtgactgaatttatggct
cgcttaccgcaacttgatcagccgtttgcagagcgtataaaagcagcagaagcagaagaa
aaagtgttacgctatgtcggattgatagaagaaggacgctgccaagtgaaaatcgttgcg
gttgatggcaatgatccgctcttcaaggtcaaaaatggcgaaaacgcattggctttctat
acgcgctattaccagccaattcctttagtactcaggggctatggagcaggtaatgatgtt
accgcagccggcgtatttgcagatatgttgcgtactctatcatggaaattgggagtctaa
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