Paenibacillus thiaminolyticus: NDS46_07505
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Entry
NDS46_07505 CDS
T08812
Symbol
cobA
Name
(GenBank) uroporphyrinogen-III C-methyltransferase
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
pthi
Paenibacillus thiaminolyticus
Pathway
pthi00860
Porphyrin metabolism
pthi01100
Metabolic pathways
pthi01110
Biosynthesis of secondary metabolites
pthi01120
Microbial metabolism in diverse environments
pthi01240
Biosynthesis of cofactors
Module
pthi_M00924
Cobalamin biosynthesis, anaerobic, uroporphyrinogen III => sirohydrochlorin => cobyrinate a,c-diamide
pthi_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
pthi00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
NDS46_07505 (cobA)
Enzymes [BR:
pthi01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
NDS46_07505 (cobA)
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
NDS46_07505 (cobA)
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Gene cluster
GFIT
Motif
Pfam:
HEM4
TP_methylase
DAHP_snth_FXD
Motif
Other DBs
NCBI-ProteinID:
WCF09708
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Position
1636984..1638549
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AA seq
521 aa
AA seq
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MEQHPRPKGVVYLVGAGPGDAGLITVKGLRCLQEADVVVYDRLAGPRLMQFAKRGARKIY
VGKLPDRHAMKQEDINRLLVELALEGHTVTRLKGGDPCVFGRVGEEAALLAEHGLRYEIV
PGVTSAVAAPAYAGIPVTHRSRASSFCVVTGHESLDKLDEMIEWDKLTQATGTLLFLMGV
AKLRYIAERLMAYGRAPDTPVALVRWGTRAEQATITGTLATIADEVERAGFASPAVIVVG
EVVRERERLQWAESRPLFGRRVLVTRARDQASELTRRIEDAGGEPYEYPVIELRMPESPA
SREALRLALAQPDAYDWLVLTSVNGVRFWFRHLREHGADIRQWAHVRIVSVGPKTTEALQ
EYGIQPDIAASQFSQEGVWEALRPHAAAGQRVLLARGDLSRSWLRETMEAHGLHANEVDL
YETVLPEEDDPELIEMLEQQMIHIVTFTSSSTVTNLMAALRRMGIDDPAQALGVARIACI
GEITARTAREAGLHVDVIAASSTIDGLMEAMMELGKMKKTV
NT seq
1566 nt
NT seq
+upstream
nt +downstream
nt
atggagcagcacccccgcccgaagggcgtcgtctatctggtcggcgccgggcccggagat
gccggattgattacggtaaaaggcctgcgctgtctgcaggaagcggatgtcgtcgtctat
gaccgcttggcaggtccgcgtctgatgcagttcgccaagcgcggagcccgtaaaatttat
gtaggaaagctgccggatcgccatgcgatgaagcaggaagacattaaccggctgctcgtc
gagttggccttggagggccatacggtaacccgtctgaagggcggagatccttgcgtattt
ggacgtgtcggcgaggaggcggccttgctggcggagcatggcctccgctatgagatcgtc
cctggcgtaacctccgccgtcgcggcgccggcgtatgccggaattccggtgacccaccgg
agtcgagcgtcgtccttctgtgtcgttaccggccacgagagtctggataagctggacgag
atgatcgagtgggacaagctgacgcaagcgacagggacgctgctctttctgatgggcgta
gcgaagctgcgctatatagccgagcggctgatggcttatggacgcgctccggatacgccg
gtggcgctcgtccgctggggaacgcgggcggagcaggcgacgataaccggcacgctggcc
acgattgccgatgaggtggagcgggccggcttcgcttcgccggccgtcatcgtcgttggc
gaggtcgtgcgggaacgggagcgtctgcagtgggcggagagccgcccgctgttcggccgg
cgcgtgctggtgacgcgcgcccgggaccaagcgagcgagttgacacgccggattgaggat
gccggcggagagccgtatgagtatccggttatcgagctcagaatgccggaatcgccggcc
tcacgtgaagcgctgcgtctggcgctcgcccagccggacgcgtatgattggctcgtgctg
acgagcgtcaacggggtccgcttctggttccgccatctgcgggagcacggggcggatatc
cgccagtgggcccatgtgcgcatcgtctcggtaggaccgaagacgacggaggcgctgcag
gaatatggaatccaacctgatattgctgcgtcccagttcagccaggagggcgtctgggaa
gcgctgcgcccacatgccgcagccgggcagcgggtactgctcgcgcgcggagatttgtcc
cgatcgtggctgagggagacgatggaagcgcatggactgcatgcgaacgaggtagatctg
tacgagacagtgctgccggaggaagacgacccggaactaatcgagatgctggagcagcag
atgattcatattgtgacgttcaccagctcttcgactgtgaccaacctgatggcggcgctg
cgccggatggggatagatgatcctgcgcaggcgctgggcgtcgcccgaatagcctgcatc
ggagagattacggcacggacggcccgggaagccggcctgcatgttgacgtaatcgcggct
tcctcgacgatcgatggactgatggaggccatgatggagttaggcaagatgaagaagaca
gtataa
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