Paenibacillus thiaminolyticus: NDS46_09450
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Entry
NDS46_09450 CDS
T08812
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
pthi
Paenibacillus thiaminolyticus
Pathway
pthi00300
Lysine biosynthesis
pthi00550
Peptidoglycan biosynthesis
pthi01100
Metabolic pathways
pthi01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
pthi00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
NDS46_09450
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
NDS46_09450
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
NDS46_09450
Enzymes [BR:
pthi01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
NDS46_09450
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Cecropin
CYNS_N
Aconitase_B_N
Motif
Other DBs
NCBI-ProteinID:
WCF10054
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Position
2108020..2109444
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AA seq
474 aa
AA seq
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MIETTLEHIAELCGGRLADPSAGQTKVRGVFTDSRSVLPGGLFVPLAGERFDGHAYVEET
LRAGAAGTLWQADRALPGASAPLIVVEDTYTALQRLAAAYLAKGQVKVVAVTGSNGKTTT
KDLVASVLSQRYRVHKTDGNFNNHIGLPLTVLAMPPETEIAVLEMGMSGRGEIELLSKLA
RPDVAIITNIGDAHLLQLGSREEIARAKLEITAGLCDGGLLVCHGDEPLVDLALSEREPG
ERIRLLRFGLGERCELRLSRISGDGTGMAFAVPSVSGQGESVFHIPLLGQHNVMNAMAAL
AVGRRFGLTDEQIAAGLAGASISGMRFERHVTPEGWIVLNDAYNASPTSMRAALSVLADM
KGGRRIAVLADMLELGPQEAELHFEIGSELTLDKVDVVLTYGELGKHIADGARQALPAES
VHSFQDKMALKAYLKQEVKPGDIVLVKASRGMKLEEVVNDWIRNTDSSVGLREV
NT seq
1425 nt
NT seq
+upstream
nt +downstream
nt
gtgatagagacaaccttggaacatatagcggagctgtgcggcggaagattggccgatccg
tctgcaggccagacgaaggtgcgcggcgtatttaccgattcccgctccgtcttgccggga
ggactgttcgttcccctcgccggtgaacgattcgacggccacgcctatgtggaggagacg
ctgcgagccggggcggccggaacgctctggcaggcggatcgggcgcttcccggcgcttcc
gcgccgcttattgtcgtggaggacacttacacggcgctgcagcggctggctgccgcttat
ctcgcgaaaggccaggtcaaggtggtcgccgttaccgggagcaacggcaagacgacgacg
aaggatctggttgcatccgtcttgtcgcaacgatatcgggtacataagaccgatgggaac
ttcaacaatcatatcgggcttccgctgacggtgctcgcgatgccgccggagacggagatt
gccgtgcttgagatgggcatgagcggccgaggagagatcgagctgctctcgaagctggcg
agaccggatgtggccattatcaccaatatcggggatgcccatcttcttcaactcggcagc
agggaggagatcgcccgggcgaagctggagattacggccggattatgcgacggcggcctg
ctcgtatgccacggagacgaaccgcttgtcgatctggcgctgtccgaacgggagccgggg
gaacgcattcgcttgctgcgcttcggtctgggcgaacgatgcgagctgcggctgtcgcgt
ataagcggcgatggcaccggtatggcattcgccgtaccttccgtcagcggacaaggcgag
tctgtcttccatatcccgctcctggggcagcataatgtgatgaacgccatggccgctctg
gcggttgggcgccgcttcggcctgacggacgaacagattgccgcaggcctggccggggcg
agcatcagcggcatgcgcttcgagcggcatgtcacgccggaaggctggatcgtgctgaat
gacgcctacaatgcgagcccgacctcgatgagggcggccttgtccgtgctggccgacatg
aagggcgggcggcgcatcgccgtgttggccgacatgctggagctgggaccgcaggaagcg
gagctccatttcgagattggatctgagcttacgttggataaggtcgatgtggtgcttacg
tacggcgaactgggcaagcatatcgccgacggggcccgccaggcgctgccggccgagtcc
gtgcactcgttccaagataaaatggctttgaaagcctatttgaagcaagaagtgaaaccc
ggcgatatcgtgctcgtcaaagcatcccggggaatgaaacttgaagaagttgtaaatgac
tggatccgtaacacggattcgtctgtggggctacgggaggtgtag
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