Pseudomonas thivervalensis: CE140_00450
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Entry
CE140_00450 CDS
T11089
Name
(GenBank) bifunctional tetrahydrofolate synthase/dihydrofolate synthase
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
pthv Pseudomonas thivervalensis
Pathway
pthv00790
Folate biosynthesis
pthv01100
Metabolic pathways
pthv01240
Biosynthesis of cofactors
Module
pthv_M00126
Tetrahydrofolate biosynthesis, GTP => THF
Brite
KEGG Orthology (KO) [BR:
pthv00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
CE140_00450
Enzymes [BR:
pthv01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
CE140_00450
6.3.2.17 tetrahydrofolate synthase
CE140_00450
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Motif
Pfam:
Mur_ligase_C
Mur_ligase_M
RecX_HTH1
Motif
Other DBs
NCBI-ProteinID:
AXA52889
UniProt:
A0A2Z4ZKF7
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Position
130763..132070
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AA seq
435 aa
AA seq
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MTQRTLGDWLAYLEQLHPSAIDMGLERSQTVASRLGLAKPAPRVITVTGTNGKGSTCAFV
ASLLRAQGLSVGVYSSPHLLRYNERVQVNGVEATDAQLCEAFAAVEAGRGDTTLTYFEMG
TLAAFWLFARAGLDAVVLEVGLGGRLDTVNLVDADIALVTSIGVDHADYLGDTRESVAFE
KAGIFRQGAPALCGDLNPPQPLLDKVRELSCPFFLRGRDFDLAMTEQHWQWRGSDLQGNP
VELRDLPLLDLPMENAALALQAYLLLGLPWEAGPIVQALQATRVVGRLDRRQFDWQGKRL
NLLLDVGHNPHAAQYLAERLARRPVIGQRLAVFGLLADKDLDGVVEALGASVQHWAVTPL
DSPRSRTAAELQDALQRHGASVQAYASVAAALEGQCALATADDEILLFGSFFCVAEALQW
LARRSTEEAADGIAG
NT seq
1308 nt
NT seq
+upstream
nt +downstream
nt
atgacccaacgcaccctgggcgactggcttgcctacctcgagcagttgcatccatcggcc
atcgacatggggctggagcgctcgcaaacggtagcgtcccgcttgggactggccaagccg
gcgccccgggtcatcaccgtcaccggcaccaatggcaagggttcgacctgcgccttcgtg
gcctcgctgctgcgggcccaggggctgagcgtcggtgtctacagctcgccgcacctgctg
cgctacaacgagcgggtgcaggtgaacggcgtcgaagcgactgacgcccagctgtgcgaa
gcctttgccgcagtggaagccgggcgaggcgatacaacccttacctatttcgagatgggc
accctggcggcgttctggttgtttgcccgtgccggtctcgacgcggtggtgctggaagtc
ggcttgggcgggcggctggatacggtcaatctggtggacgcggacattgcgctggtcact
agcattggcgtggaccatgccgattacctgggcgatacccgtgaatccgtggccttcgag
aaggctggcatcttccgccagggcgcgcctgcgctctgtggcgatctcaatcctccccag
ccactgctggacaaggtgcgcgagctgagttgcccgttcttcctgcgtgggcgggatttc
gacctggcgatgaccgagcagcattggcaatggcgcggcagcgacctgcagggcaatccg
gtggagttgcgcgacctgccactgctggacctgccgatggaaaacgccgcactggcgctc
caggcctacctgttgctgggcttgccctgggaggccgggccaatcgtccaggcgttgcag
gcgacccgcgtggtcgggcgccttgatcgccgtcagttcgattggcaaggcaagcgcctg
aacctgttgctggacgttggccataacccccatgcggcgcagtacctggccgaacgcctg
gctcggcggcccgtgatcgggcagcgcctggcggtgttcgggctgctggccgacaaggat
ctggatggcgttgtcgaggcgttgggtgctagtgtccagcattgggcggtgacgccgctg
gattcgccgcgctcgcgtacggcggctgagttgcaggatgcgttgcagcgtcatggtgct
tcagtgcaagcctacgcgagtgtggccgctgccctggaagggcagtgcgcgctggcgaca
gccgatgacgaaatcctgctgttcggatcatttttttgtgttgccgaggcccttcaatgg
ctggcccggcgctccacggaggaagctgcagatggcattgctggataa
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