Parageobacillus thermoglucosidasius DSM 2542: AOT13_17720
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Entry
AOT13_17720 CDS
T04476
Name
(GenBank) 2-isopropylmalate synthase
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
ptl
Parageobacillus thermoglucosidasius DSM 2542
Pathway
ptl00290
Valine, leucine and isoleucine biosynthesis
ptl00620
Pyruvate metabolism
ptl01100
Metabolic pathways
ptl01110
Biosynthesis of secondary metabolites
ptl01210
2-Oxocarboxylic acid metabolism
ptl01230
Biosynthesis of amino acids
Module
ptl_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
ptl00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
AOT13_17720
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
AOT13_17720
Enzymes [BR:
ptl01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
AOT13_17720
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Gene cluster
GFIT
Motif
Pfam:
HMGL-like
LeuA_dimer
HCS_D2
BP28CT
Motif
Other DBs
NCBI-ProteinID:
ALF11711
UniProt:
A0AAN0YSC1
A0AB38QZM5
LinkDB
All DBs
Position
complement(3594566..3596113)
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AA seq
515 aa
AA seq
DB search
MRKINIFDTTLRDGEQSAGINLNLQEKLEIARQLERLGVDIIEAGFPAASKGDFQAVKQI
AETIKTCSVTGLSRSVQSDIDAAWEALKGGAEPRLHLFIATSPIHMTHKLRMTPEQVIET
AVSSVKYAKRYFPIVQWSAEDACRSELPFLVKIITEVIKAGATVINIPDTVGYITPKEYG
NIFTFLLNNVPNIEKVSLSAHCHDDLGMAVANSLAAIEHGATQIEGTINGIGERAGNAAL
EEIAVALYIRKDYYQAETRLNLQEIKRTSNLVSKLTGVVIPPNKAVVGKNAFAHESGIHQ
DGVLKEKTTYEIISPELVGVQSNSMVLGKHSGRHALRNRVEELGYKLSDEEINKLFVRFK
ELADKKKDITDDDLVALIFEEKFDHFKDFYQLTSLQVQYGTNQIPTAVVVLKDGEGNEIQ
EAATGAGSVEALYNTLERCFKTPVTLLDYRIESVSGGRDALAQVFVKVRVNDIETSGRGT
AQDVLEASAKAYINAVNRVFMIETMRAENPKVAMQ
NT seq
1548 nt
NT seq
+upstream
nt +downstream
nt
gtgagaaaaattaacatttttgatacgacattgcgtgacggtgaacagtctgctgggatc
aatttgaatttgcaagaaaagctggagattgcccgccagcttgaacggctcggcgttgat
attattgaagcaggctttcctgccgcatcgaaaggggattttcaagcggtaaaacaaatt
gcggaaacgatcaaaacatgctctgttaccgggctgtcccgctcggtgcagagcgatatt
gacgccgcatgggaagcgttaaaaggaggcgcggagccccgcctccacttgttcatcgcc
acatcgccgatccatatgacacacaaattgcggatgacgccggaacaagtcattgaaacg
gcggtatcttccgtgaaatatgcaaaacgctattttccgattgtccaatggtcggcggaa
gacgcctgccgcagcgaacttccttttttggtaaaaattattacggaagtgattaaagcg
ggagcgacggtcattaatatcccagatacagtaggatatattactccgaaagagtatgga
aacattttcacctttttgctcaataatgttccgaatattgaaaaagtatcgctttctgcc
cattgccatgacgatttaggaatggcggttgccaattcgctagcagcaatcgagcatggc
gccacacaaatcgaagggacgattaacggaatcggcgaacgcgcgggaaatgcggcattg
gaagaaatcgctgtcgcgctttacattcgcaaagattattatcaggcagaaacgcgccta
aacctgcaagaaattaagcggacgagcaatttagtcagcaaattgacaggcgtggtcatt
ccgccaaacaaagcggtcgtcggcaaaaacgccttcgcacatgagtcaggaatccatcaa
gatggcgtattaaaagaaaaaacaacgtatgaaattatttccccagaacttgtcggggtt
caatccaactcaatggtgcttggaaaacattccggacgccacgcgctgcgcaatcgtgtc
gaagaacttggatacaaattatcagatgaagaaattaataaactgtttgtccggtttaaa
gaactggccgataagaaaaaagacattaccgatgatgatttagtcgcacttatttttgaa
gaaaaatttgaccactttaaagatttttatcagctgacttcacttcaagtccagtatgga
acgaaccaaattccgaccgctgttgtcgtcttaaaggacggagaaggaaatgaaattcaa
gaagcggcaacaggagccggaagcgtcgaagcgttgtataacacgttagagcgctgcttt
aaaacgccggttacgttgcttgactatcggattgaatcggtcagcggcggacgtgatgcg
cttgcgcaagtgtttgtgaaagtgcgggtgaacgacattgaaacaagcgggcgcggcacg
gcgcaggacgtgctggaagcttccgctaaagcgtacattaacgcagtcaaccgcgtgttt
atgattgaaacgatgcgtgcggaaaatccaaaagttgcgatgcaataa
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