Panthera uncia (snow leopard): 125908731 Help Entry 125908731         CDS       T08832                                  Name (RefSeq) hypoxia-inducible factor 1-alpha   KO K08268   hypoxia-inducible factor 1 alpha Organism puc  Panthera uncia (snow leopard) Pathway puc04066   HIF-1 signaling pathway puc04137   Mitophagy - animal puc04140   Autophagy - animal puc04148   Efferocytosis puc04659   Th17 cell differentiation puc04919   Thyroid hormone signaling pathway puc05167   Kaposi sarcoma-associated herpesvirus infection puc05200   Pathways in cancer puc05205   Proteoglycans in cancer puc05208   Chemical carcinogenesis - reactive oxygen species puc05211   Renal cell carcinoma puc05230   Central carbon metabolism in cancer puc05231   Choline metabolism in cancer puc05235   PD-L1 expression and PD-1 checkpoint pathway in cancer Brite KEGG Orthology (KO) [BR:puc00001]  09130 Environmental Information Processing   09132 Signal transduction    04066 HIF-1 signaling pathway     125908731  09140 Cellular Processes   09141 Transport and catabolism    04140 Autophagy - animal     125908731    04137 Mitophagy - animal     125908731    04148 Efferocytosis     125908731  09150 Organismal Systems   09151 Immune system    04659 Th17 cell differentiation     125908731   09152 Endocrine system    04919 Thyroid hormone signaling pathway     125908731  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     125908731    05205 Proteoglycans in cancer     125908731    05208 Chemical carcinogenesis - reactive oxygen species     125908731    05230 Central carbon metabolism in cancer     125908731    05231 Choline metabolism in cancer     125908731    05235 PD-L1 expression and PD-1 checkpoint pathway in cancer     125908731   09162 Cancer: specific types    05211 Renal cell carcinoma     125908731   09172 Infectious disease: viral    05167 Kaposi sarcoma-associated herpesvirus infection     125908731  09180 Brite Hierarchies   09182 Protein families: genetic information processing    03000 Transcription factors [BR:puc03000]     125908731 Transcription factors [BR:puc03000]  Eukaryotic type   Basic helix-loop-helix (bHLH)    Factors with PAS domain     125908731 BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  bHLH_HIF1A PAS_3 PAS_11 HIF-1a_CTAD PAS HIF-1 PAS_9 PAS_4 HLH DDRGK Motif Other DBs NCBI-GeneID:  125908731 NCBI-ProteinID:  XP_049467466 LinkDB All DBs Position B3 Genome browser AA seq 824 aa AA seqDB search MEGAGGANDKKKISSERRKEKSRDAARSRRSKESEVFYELAHQLPLPHNVSSHLDKASVM RLTISYLRVRKLLDAGDLDIEDEMKAQMNCFYLKALDGFVMVLTDDGDMIYISDNVNKYM GLTQFELTGHSVFDFTHPCDHEEMREMLTHRNGLVKKGKEQNTQRSFFLRMKCTLTSRGR TMNIKSATWKVLHCTGHIHVYDTNSNQSQCGYKKPPMTCLVLICEPIPHPSNIEIPLDSK TFLSRHSLDMKFSYCDERITELMGYEPEELLGRSIYEYYHALDSDHLTKTHHDMFTKGQV TTGQYRMLAKRGGYVWVETQATVIYNTKNSQPQCIVCVNYVVSGIIQHDLIFSLQQTECV LKPVESSDMKMTQLFTKVESEDTSSLFDKLKKEPDALTLLAPAAGDTIISLDFGSNDTET DDQQLEEVPLYNDVMLPSSNEKLQNINLAMSPLPASETPKPLRSSADPALNQEVVLKLEP NPESLELSFTMPQIQDQPASPSDGSTRQSSPEPTSPSEYCFDVDSDMVNEFKLELVEKLF AEDTEAKNPFSTQDTDLDLEMLAPYIPMDDDFQLRSFDQLSPLESSSTSPQSVGTITVFQ PAQMQEEPPVTTTSTTATTDELKTVTKDGIEDIKILIASPSPTHVPKVTTGATTSLYGDT GSRTASPNRAGKGVIEQTEKSHPRSPNVLSVTLSQRTTIPEEELNPKILALQNAQRKRKI EHDGSLFQAVGIGTLLQQPDDRATTTSLSWKRVKGCKSSEQNGMEQKTIILIPSDLACRL LGQSMDESGLPQLTSYDCEVNAPVQGSRNLLQGEELLRALDQVN NT seq 2475 nt NT seq  +upstreamnt  +downstreamnt atggagggcgccggcggcgcgaacgacaagaaaaagataagttctgaacgtcgaaaagaa aagtctagagatgcagcgagatctcggcgaagtaaagagtctgaagttttctatgaactt gctcatcagttgccacttccccataatgtgagctcgcatctcgataaggcttctgttatg aggctcaccatcagctatttgcgtgtgaggaaacttctggatgctggtgatttagatatt gaagatgaaatgaaggcacagatgaattgcttttatttgaaagccttggatggttttgtt atggttctcacagatgatggtgacatgatctacatttctgataatgtgaacaagtacatg ggattaactcagtttgaactaactggacacagtgtgtttgattttactcatccatgtgac catgaagaaatgagagaaatgcttacacatagaaatggccttgtgaagaagggtaaagag cagaatacacagcgaagcttttttctcagaatgaagtgtaccctaactagccgagggaga accatgaacataaagtcagcaacgtggaaagtacttcactgcacaggccatattcatgtc tacgataccaatagtaaccaatctcagtgtgggtataagaaaccacccatgacgtgcttg gtgctgatttgtgaacccattcctcatccatcaaatattgaaattcctttagatagcaag acttttctgagtcgtcatagtctggatatgaaattttcttactgtgatgaaagaattact gaattgatgggatatgagccagaggaacttttgggccgctcaatatatgaatattaccac gctttggactctgaccatctgaccaaaactcatcatgacatgtttactaaaggccaagtc accacaggacagtacaggatgcttgccaaaagaggtggatatgtctgggttgaaactcaa gcgaccgtcatatataacactaagaactctcaaccacagtgcattgtatgtgtaaattac gttgtgagtggtattattcagcacgacttgattttctcccttcaacaaacagaatgtgtc ctcaaaccagttgaatcttcagatatgaaaatgactcagctgttcaccaaagttgaatca gaagacacaagtagtctgtttgataaacttaagaaggaacctgatgctttaactttgctg gccccagctgctggagacacaatcatatctttagatttcggcagcaatgacacagaaact gatgaccagcaacttgaggaagttccattgtataatgatgtaatgcttccctcatccaat gaaaaattacagaacataaatttggcaatgtctccattacctgcttctgaaactccaaag ccacttcgaagtagtgctgaccctgcactcaatcaagaagttgtactaaaattagagcca aatccagagtcactggaactttcttttactatgccccagattcaagatcagccagctagt ccttctgatggaagcactagacagagttcacctgagcctaccagtcccagtgaatattgt tttgatgtggatagtgatatggtcaatgaatttaagctggaattggtagagaaacttttt gctgaagacacagaagccaagaatccattttccacccaggacacggatttagacttggag atgttagctccttacatcccaatggatgatgacttccagttacgttcctttgatcagttg tcgccactggaaagcagttctacaagccctcaaagcgtgggcacaattacagtattccag ccggctcagatgcaggaggaacctcctgttaccactaccagtaccactgccaccactgat gaattaaaaacagtgacaaaagatggtatagaagacattaaaatactgattgcatctcca tctcctacccatgtacccaaagtaactactggtgccacaacatcactgtatggtgatact ggaagtcggacagcctcaccaaacagagcaggaaaaggagtcatagaacagacagaaaaa tctcatccaagaagccctaatgtgttatctgtcactttgagtcaaagaactaccattcct gaagaagaactaaatccaaagatactagctttgcagaatgctcagagaaagcgaaaaata gaacatgacggttcactttttcaagcagtaggaattggaacattattacagcagccagat gatcgtgcaactactacatcactttcttggaaacgcgtaaaaggatgcaaatctagtgag cagaatggaatggagcaaaagacaattattttaataccctctgatttagcatgtagactg ctggggcaatcaatggatgagagtggattaccacaactgaccagttatgattgtgaagtt aatgctcctgtacaaggcagcagaaacctactgcagggtgaagaattactcagagctttg gatcaagttaactga

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