Panthera uncia (snow leopard): 125911273
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Entry
125911273 CDS
T08832
Name
(RefSeq) NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial isoform X1
KO
K03934
NADH dehydrogenase (ubiquinone) Fe-S protein 1 [EC:
7.1.1.2
]
Organism
puc
Panthera uncia (snow leopard)
Pathway
puc00190
Oxidative phosphorylation
puc01100
Metabolic pathways
puc04714
Thermogenesis
puc04723
Retrograde endocannabinoid signaling
puc04932
Non-alcoholic fatty liver disease
puc05010
Alzheimer disease
puc05012
Parkinson disease
puc05014
Amyotrophic lateral sclerosis
puc05016
Huntington disease
puc05020
Prion disease
puc05022
Pathways of neurodegeneration - multiple diseases
puc05208
Chemical carcinogenesis - reactive oxygen species
puc05415
Diabetic cardiomyopathy
Module
puc_M00143
NADH dehydrogenase (ubiquinone) Fe-S protein/flavoprotein complex, mitochondria
Brite
KEGG Orthology (KO) [BR:
puc00001
]
09100 Metabolism
09102 Energy metabolism
00190 Oxidative phosphorylation
125911273
09150 Organismal Systems
09156 Nervous system
04723 Retrograde endocannabinoid signaling
125911273
09159 Environmental adaptation
04714 Thermogenesis
125911273
09160 Human Diseases
09161 Cancer: overview
05208 Chemical carcinogenesis - reactive oxygen species
125911273
09164 Neurodegenerative disease
05010 Alzheimer disease
125911273
05012 Parkinson disease
125911273
05014 Amyotrophic lateral sclerosis
125911273
05016 Huntington disease
125911273
05020 Prion disease
125911273
05022 Pathways of neurodegeneration - multiple diseases
125911273
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
125911273
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
125911273
Enzymes [BR:
puc01000
]
7. Translocases
7.1 Catalysing the translocation of protons
7.1.1 Linked to oxidoreductase reactions
7.1.1.2 NADH:ubiquinone reductase (H+-translocating)
125911273
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Gene cluster
GFIT
Motif
Pfam:
Molybdopterin
Fer4_Nqo3
Fer4_NDSU1
Fer2_4
NADH-G_4Fe-4S_3
NADH_dhqG_C
Fer2
Motif
Other DBs
NCBI-GeneID:
125911273
NCBI-ProteinID:
XP_049471024
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Position
C1
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AA seq
727 aa
AA seq
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MLRIPLKRALVGLSKSHKGCVRTTATAASNLIEVFVDGQSVMVEPGTTVLQACEKVGMQI
PRFCYHERLSVAGNCRMCLVEIEKAPKVVAACAMPVMKGWNILTNSEKSKKAREGVMEFL
LANHPLDCPICDQGGECDLQDQSMMFGNDRSRFLDGKRAVEDKNIGPLVKTIMTRCIQCT
RCIRFASEIAGVDDLGTTGRGNDMQVGTYIEKMFMSELSGNIIDICPVGALTSKPYAFTA
RPWETRKTESIDVMDAVGSNIVVSTRTGEVMRILPRMHEDINEEWISDKTRFAYDGLKRQ
RLTEPMVRNEKGLLTYTSWEDALSRVAGMLQSVQGKDVAAIAGGLVDAEALVALKDLLNR
VDSDTLCTEEVFPTAGAGTDLRSNYLLNTTIAGVEEADVLLLVGTNPRFEAPLFNARIRK
SWLHNDLKVALIGSPVDLTYRYDHLGDSPKILQEIALGNHPFSQVLHEAKKPVVVLGSSA
LQRNDGAAILAAVSNIAQKIRMSSGVTSDWKVMNILHRIASQVAALDLGYKPGVETIRKS
PPKVLFLLGADGGCITRQDLPKDCFIIYQGHHGDVGAPIADVILPGAAYTEKSATYVNTE
GRAQQTRVAVTPPGLAREDWKIIRALSEIAGMTLPYDTLDQVRNRLEEVSPNLVRYDDVE
GANYFQQANELSKLVNQQLLADPLVPPQLTIKDFYMTDSISRASQTMAKCVKAVTEGAQA
VEEPSIC
NT seq
2184 nt
NT seq
+upstream
nt +downstream
nt
atgttaaggatacctctaaaaagggccttagtaggcctttctaagtctcataaaggatgt
gttcgaacaactgccacagcagcaagcaacttaattgaagtatttgtcgatggtcagtct
gtcatggtggaaccaggaactaccgtactccaagcttgtgagaaggttggcatgcagatc
cctcgattctgttatcatgaaagattgtctgttgctggaaactgtaggatgtgccttgtt
gaaattgagaaagctcctaaggttgtggcagcttgtgccatgccagtaatgaaaggttgg
aatatcctgacaaactcagagaaatctaagaaagcaagagaaggtgtgatggagttcttg
ttagcaaatcacccactggactgtcctatttgtgaccagggaggtgaatgtgatctgcag
gaccagtccatgatgtttggaaatgataggagcagatttttagatgggaaacgtgctgtg
gaggacaagaatattgggccattggtaaagactatcatgactagatgtatacagtgtact
cgctgcatcaggtttgcaagtgagattgcaggagtagatgatttgggaacaacaggcaga
ggaaatgatatgcaagttggcacgtacattgaaaagatgttcatgtctgaactgtctgga
aatatcattgatatctgccctgtaggtgccctgacttcgaagccctatgcttttactgcc
cgcccttgggaaacaagaaagacggaatccattgatgtaatggatgcagttggaagtaat
attgtggtaagcacaagaactggagaggtgatgcggattttgccaaggatgcatgaggac
atcaatgaagagtggatctctgataaaaccagatttgcctatgatgggctaaaacgtcaa
agactaaccgagccaatggtcagaaatgaaaaggggcttttaacctacacttcctgggaa
gatgcactctctcgtgtagctggaatgttgcagagtgttcaaggcaaggatgtggcagca
attgcaggtggcttggtggatgctgaagccctggtagctctcaaagatttgcttaataga
gtggactctgacaccttgtgcactgaagaggtcttccccactgcaggagctggcacagat
ttgcgttctaattatcttcttaatactacaattgctggtgtggaagaggcagatgttctc
cttctggttggtacaaatccgcgttttgaggcgccactgtttaatgctagaattcgaaag
agctggcttcataatgacttaaaagtggcccttattggcagcccagtggatctcacttac
agatatgaccatctgggagattcccccaaaattcttcaggagattgctttgggtaaccat
ccgttcagccaggtattacatgaagctaaaaaaccagtggtggttttaggcagttctgca
ctccaaagaaatgatggggcagcaattcttgcagctgtttccaacattgctcaaaagatt
cggatgagtagtggtgttaccagtgattggaaagttatgaatatccttcataggattgca
agccaagtagctgctttggaccttggctataaacctggggtggaaacaattcgtaaaagc
cctcccaaagtgctatttctcctgggagcagatggaggttgtatcactcgacaggatttg
ccaaaggattgtttcattatttatcaaggacatcatggagacgttggagctccaatagct
gatgttattctcccaggcgctgcttacacagaaaagtcagccacttatgtcaatactgaa
ggccgagctcagcagacaagggtagcagtgacacctcctggcttggcaagagaagactgg
aaaattataagagccctctctgagattgcaggtatgactcttccatatgatactctggat
caagtaaggaacagattggaggaagtctctcctaatcttgtccgatatgatgatgtcgaa
ggagccaattatttccagcaagcaaatgagctctccaagctagtgaaccagcaacttctt
gctgatccgcttgttccacctcagctaacaataaaagacttctacatgacagactcaatt
agcagagcctcacagacaatggccaaatgtgtcaaagctgtcacagaaggtgcccaagca
gtagaggagccatccatttgctga
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