KEGG   Panthera uncia (snow leopard): 125914402
Entry
125914402         CDS       T08832                                 
Name
(RefSeq) rho-associated protein kinase 1 isoform X1
  KO
K04514  Rho-associated protein kinase 1 [EC:2.7.11.39]
Organism
puc  Panthera uncia (snow leopard)
Pathway
puc04022  cGMP-PKG signaling pathway
puc04024  cAMP signaling pathway
puc04062  Chemokine signaling pathway
puc04071  Sphingolipid signaling pathway
puc04270  Vascular smooth muscle contraction
puc04350  TGF-beta signaling pathway
puc04360  Axon guidance
puc04510  Focal adhesion
puc04520  Adherens junction
puc04530  Tight junction
puc04611  Platelet activation
puc04670  Leukocyte transendothelial migration
puc04810  Regulation of actin cytoskeleton
puc04921  Oxytocin signaling pathway
puc05135  Yersinia infection
puc05163  Human cytomegalovirus infection
puc05200  Pathways in cancer
puc05205  Proteoglycans in cancer
puc05206  MicroRNAs in cancer
Brite
KEGG Orthology (KO) [BR:puc00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04350 TGF-beta signaling pathway
    125914402
   04071 Sphingolipid signaling pathway
    125914402
   04024 cAMP signaling pathway
    125914402
   04022 cGMP-PKG signaling pathway
    125914402
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    125914402
   04520 Adherens junction
    125914402
   04530 Tight junction
    125914402
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    125914402
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    125914402
   04670 Leukocyte transendothelial migration
    125914402
   04062 Chemokine signaling pathway
    125914402
  09152 Endocrine system
   04921 Oxytocin signaling pathway
    125914402
  09153 Circulatory system
   04270 Vascular smooth muscle contraction
    125914402
  09158 Development and regeneration
   04360 Axon guidance
    125914402
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    125914402
   05206 MicroRNAs in cancer
    125914402
   05205 Proteoglycans in cancer
    125914402
  09172 Infectious disease: viral
   05163 Human cytomegalovirus infection
    125914402
  09171 Infectious disease: bacterial
   05135 Yersinia infection
    125914402
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:puc01001]
    125914402
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins [BR:puc03036]
    125914402
Enzymes [BR:puc01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.39  ROCK-subfamily protein kinase
     125914402
Protein kinases [BR:puc01001]
 Serine/threonine kinases: AGC group
  DMPK family [OT]
   125914402
Chromosome and associated proteins [BR:puc03036]
 Eukaryotic type
  Centrosome formation proteins
   Kinases and associated factors
    125914402
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Rho_Binding PH C1_1 Pkinase_C APH DUF1192
Other DBs
NCBI-GeneID: 125914402
NCBI-ProteinID: XP_049475604
LinkDB
Position
D3
AA seq 1397 aa
MSTGDSFETRFEKIDNLLRDPKSEVNSDCLLDGLDALVYDLDFPALRKNKNIDNFLSRYK
DTINKIRDLRMKAEDYEVVKVIGRGAFGEVQLVRHKSTRKVYAMKLLSKFEMIKRSDSAF
FWEERDIMAFANSPWVVQLFYAFQDDRYLYMVMEYMPGGDLVNLMSNYDVPEKWARFYTA
EVVLALDAIHSMGFIHRDVKPDNMLLDKSGHLKLADFGTCMKMNKEGMVRCDTAVGTPDY
ISPEVLKSQGGDGYYGRECDWWSVGVFLYEMLVGDTPFYADSLVGTYSKIMNHKNSLTFP
DDNDISKEAKNLICAFLTDREVRLGRNGVEEIKRHLFFKNDQWAWETLRDTVAPVVPDLS
SDIDTSNFDDLEEDKGDEETFPIPKAFVGNQLPFVGFTYYSNRRYLSSANPNDNRSSPNV
DKSLQENLQKTIYKLEEQLHNEMQLKDEMEQKCRTSNIKLDKIMKELDEEGNQRRNLEST
VSQIEKEKMLLQHRINEYQRKVEQENEKRRNVENEVSTLKDQLEDLKKVSQNSQLANEKL
TQLQKQLEEANDLLRTESDTAVRLRKSHTEMSKSISQLESLNRELQERNRILENSKTQMD
KDYYQLQAVLEAERRDRGHDSEMIGDLQARITSLQEEVKHLKHNLERVEGERKEAQDMLN
HSEKEKNNLEIDLNYKLKSLQQRLEQEVNEHKVTKARLTDKHQSIEEAKSVAMCEMEKKL
KEEREAREKAENRVVQIEKQCSMLDVDLKQSQQKLEHLTENKERMEDEVKNLSLQLEQES
NKRVLLQNELKTQAFEADNLKGLEKQMKQEINTLLEAKRLLEFELAQLTKQYRGNEGQMR
ELQDQLEAEQYFSTLYKTQVKELKEEIEEKNRENLKKIQELQNEKETLTTQLDLAETKAE
SEQLARGLLEEQYFELTQESKKAASRNRQEITDKDHTVSRLEETNSMLTKDLELLRKENE
ELTDKVRRTEEEYKLKKEEEINNLKATYEKNISTERTLKTQAVNKLAEIMNRKDFKIDRK
KANTQDLRKKEKENRKLQLELNQEREKFNQMVVKHQKELNDMQAQLVEECTHRNELQMQL
ASKESDIEQLRAKLLDLSDSTSVASFPSADETDGNLPESRIEGWLSIPNRGNIKRYGWKK
QYVVVSSKKILFYNDEQDKEQSNPSMVLDIDKLFHVRPVTQGDVYRAETEEIPKIFQILY
ANEGECRKDVEMEPVQQAEKTNFQNHKGHEFIPTLYHFPANCEACAKPLWHVFKPPPALE
CRRCHVKCHRDHLDKKEDLISPCKVSYDVTSARDMLLLACSQDEQKKWVTHLVKKIPKNP
PSGFVRASPRTLSTRSTANQSFRKVVKNTSAKTSILELNLQDLRGIPVCRCYCIQKNKCY
ISYSLSVMGQFISLPLS
NT seq 4194 nt   +upstreamnt  +downstreamnt
atgtcgactggggacagttttgagactcggtttgaaaaaatcgacaacctgctgcgggat
cccaaatcggaagtgaattcggattgtttgctggatggattggatgctttggtatatgat
ttggattttcctgccttaagaaaaaacaaaaatattgacaactttttaagcagatataaa
gacacaataaataaaattagagatttacgaatgaaagctgaagattatgaagtagtgaag
gtgattggtagaggtgcatttggagaagttcaattggtaaggcataaatccaccaggaag
gtatatgctatgaagcttcttagtaaatttgaaatgattaagagatctgattctgctttt
ttctgggaagaaagagacatcatggcttttgctaacagtccttgggtcgttcagcttttt
tatgcattccaagatgatcgttatctctacatggtgatggagtacatgcctggtggagat
cttgtaaacttaatgagcaactatgatgtgcctgaaaaatgggcacgattctacactgca
gaagtagttcttgcattggatgcaatccattccatgggtttcattcatagagatgtgaag
cctgataacatgctgctggataaatctggacatttgaagttagcagattttggtacttgt
atgaagatgaataaggaaggtatggtacgatgtgatacagcagttggaacacccgattac
atttcccctgaagtattaaaatctcaaggtggtgatggttattatggacgagaatgtgac
tggtggtcagttggggtatttttatatgaaatgcttgtaggtgatacacctttttatgca
gattctctggttggaacttatagtaagattatgaaccataaaaattcacttactttccct
gatgataatgatatatcaaaagaagcaaaaaatcttatttgtgccttccttactgacaga
gaggtgagattaggacgaaatggtgtggaagaaatcaaacgacatcttttcttcaaaaat
gatcagtgggcttgggaaacactcagagacactgtagcgccagttgtacctgatttaagt
agcgacattgatacaagtaattttgatgacttggaagaagataaaggagatgaagaaaca
ttccctatacctaaagcttttgttggcaatcagttaccttttgtaggatttacgtattat
agcaatcgtagatacttatcttcagcaaatcctaatgataaccgaagtagccccaatgtg
gataaaagcttgcaggaaaatttgcaaaaaacaatttataagctggaagaacaactgcat
aatgaaatgcaattaaaagatgaaatggagcagaagtgcagaacttcaaacataaaacta
gacaagataatgaaagaattggatgaagagggaaatcaaagaagaaacctagagtctaca
gtgtctcagattgagaaagagaaaatgttgctacagcatagaattaatgagtaccaaaga
aaagtagaacaggaaaatgagaagaggagaaatgtagaaaatgaagtttctacattaaag
gatcagttagaagacttaaagaaagtaagtcagaattcacagcttgctaatgagaagctg
acacagttacaaaagcagctagaagaagccaatgacttacttaggacagaatcagacaca
gctgtaagattaaggaagagtcacacagagatgagtaagtcaattagtcagctagagtcc
ttaaacagagaattgcaggagagaaatagaattttagagaattccaagacacaaatggac
aaggactattaccagctgcaagctgtgttagaagctgaacgaagagacagaggtcatgat
tctgagatgattggagaccttcaagctcgaattacatctttacaagaagaggtaaagcat
ctcaagcataatcttgaaagagtggaaggagaaagaaaagaagctcaagacatgcttaat
cactcagaaaaagaaaagaataatttagagatagatttaaactataagcttaaatcatta
caacaaaggttagaacaagaggtaaatgaacataaagtaaccaaagctcgtttaactgac
aaacatcagtctattgaagaggcaaagtctgttgcaatgtgtgaaatggaaaagaagctg
aaggaagagagagaagctcgagagaaggctgaaaatagagttgttcagattgagaaacag
tgttcaatgctagatgttgatctgaaacaatctcagcagaagcttgagcatttgactgaa
aataaagaaaggatggaggatgaagttaagaatctatccctgcaactggagcaggaatca
aataagcgagtattgttacagaatgaattgaagactcaagcgtttgaagcggacaattta
aaaggtctagaaaagcagatgaaacaggaaataaatactttattggaagcaaagagatta
ttagaatttgagttagctcagcttacaaaacagtatagaggaaatgaaggacagatgcgg
gagctacaagatcagcttgaagcagagcaatatttttcgacactttataaaacccaagta
aaggaacttaaggaagaaattgaagaaaaaaacagagaaaatttaaagaaaatacaggaa
ctacaaaatgaaaaagaaactcttactactcagttggatctagcagaaacaaaagccgag
tctgagcagttggctcgagggcttctggaagaacagtattttgaattgacccaagaaagc
aagaaagctgcctcaagaaatagacaggagattacagataaagatcacactgttagtcgg
cttgaagaaacaaacagcatgctaaccaaagatcttgagttattaagaaaagaaaatgaa
gagctaactgataaagtgaggaggacagaggaagaatataaactgaagaaagaggaagag
atcaataatcttaaggctacctatgaaaagaatatcagtacagaaagaacccttaaaaca
caggctgttaacaagttggcagaaataatgaatcggaaagattttaaaattgatagaaag
aaagctaatacacaggatttgagaaagaaagaaaaggaaaatcgaaagcttcaactggaa
ctcaaccaagaaagagagaaattcaaccagatggtggtgaaacatcagaaggaactgaat
gacatgcaagcgcaattggtagaagaatgtacacataggaatgagcttcagatgcaattg
gctagcaaagagagtgatattgagcaattgcgtgctaaacttttggacctttcggattct
acaagtgttgctagttttcctagtgctgatgaaactgatggaaaccttccagagtcaaga
attgaaggctggctttcaataccaaacagaggaaatatcaaacgatatggctggaagaaa
cagtatgttgtagtaagcagcaaaaaaattttgttctataatgatgagcaagataaggaa
caatccaatccatccatggtattggacatagataaattgtttcatgttcgacctgtaacc
caaggagatgtttacagagctgaaactgaagaaattcctaaaatattccagatactatat
gcaaatgaaggtgaatgtagaaaagatgtagagatggaaccagtacagcaagctgaaaag
actaattttcaaaaccacaaaggccatgagttcattcctacactctaccactttcccgcc
aactgtgaggcctgtgccaaacctctctggcatgtttttaagccacctcctgccctagaa
tgtcgaagatgccatgttaagtgccacagagatcacttagataagaaagaggacttaatt
tctccatgtaaagtcagttatgatgtaacatcagcaagagatatgctgctgttagcatgt
tctcaggatgaacaaaaaaaatgggtaacacatttggtgaagaagatccctaagaatcca
ccatctggttttgttcgtgcatcccctcgaacactttctacaagatccactgcaaatcag
tctttccgaaaagtggtcaaaaatacatctgcaaaaactagcattctggaactgaacctg
caagatctccgaggtatacctgtatgtagatgttattgtatacagaaaaacaaatgttat
atttcttatagtttgagtgtcatgggacaatttatatcattgcctttgtcatag

DBGET integrated database retrieval system