KEGG   Panthera uncia (snow leopard): 125917114
Entry
125917114         CDS       T08832                                 
Name
(RefSeq) mitogen-activated protein kinase 10
  KO
K04440  mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
Organism
puc  Panthera uncia (snow leopard)
Pathway
puc01522  Endocrine resistance
puc04010  MAPK signaling pathway
puc04012  ErbB signaling pathway
puc04014  Ras signaling pathway
puc04024  cAMP signaling pathway
puc04068  FoxO signaling pathway
puc04071  Sphingolipid signaling pathway
puc04137  Mitophagy - animal
puc04140  Autophagy - animal
puc04141  Protein processing in endoplasmic reticulum
puc04210  Apoptosis
puc04215  Apoptosis - multiple species
puc04217  Necroptosis
puc04310  Wnt signaling pathway
puc04380  Osteoclast differentiation
puc04510  Focal adhesion
puc04530  Tight junction
puc04620  Toll-like receptor signaling pathway
puc04621  NOD-like receptor signaling pathway
puc04622  RIG-I-like receptor signaling pathway
puc04625  C-type lectin receptor signaling pathway
puc04657  IL-17 signaling pathway
puc04658  Th1 and Th2 cell differentiation
puc04659  Th17 cell differentiation
puc04660  T cell receptor signaling pathway
puc04664  Fc epsilon RI signaling pathway
puc04668  TNF signaling pathway
puc04722  Neurotrophin signaling pathway
puc04723  Retrograde endocannabinoid signaling
puc04728  Dopaminergic synapse
puc04750  Inflammatory mediator regulation of TRP channels
puc04910  Insulin signaling pathway
puc04912  GnRH signaling pathway
puc04914  Progesterone-mediated oocyte maturation
puc04917  Prolactin signaling pathway
puc04920  Adipocytokine signaling pathway
puc04926  Relaxin signaling pathway
puc04930  Type II diabetes mellitus
puc04931  Insulin resistance
puc04932  Non-alcoholic fatty liver disease
puc04933  AGE-RAGE signaling pathway in diabetic complications
puc04935  Growth hormone synthesis, secretion and action
puc04936  Alcoholic liver disease
puc05010  Alzheimer disease
puc05012  Parkinson disease
puc05016  Huntington disease
puc05017  Spinocerebellar ataxia
puc05020  Prion disease
puc05022  Pathways of neurodegeneration - multiple diseases
puc05132  Salmonella infection
puc05133  Pertussis
puc05135  Yersinia infection
puc05142  Chagas disease
puc05145  Toxoplasmosis
puc05152  Tuberculosis
puc05161  Hepatitis B
puc05162  Measles
puc05166  Human T-cell leukemia virus 1 infection
puc05167  Kaposi sarcoma-associated herpesvirus infection
puc05169  Epstein-Barr virus infection
puc05170  Human immunodeficiency virus 1 infection
puc05171  Coronavirus disease - COVID-19
puc05200  Pathways in cancer
puc05208  Chemical carcinogenesis - reactive oxygen species
puc05210  Colorectal cancer
puc05212  Pancreatic cancer
puc05231  Choline metabolism in cancer
puc05415  Diabetic cardiomyopathy
puc05417  Lipid and atherosclerosis
puc05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:puc00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04141 Protein processing in endoplasmic reticulum
    125917114
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    125917114
   04012 ErbB signaling pathway
    125917114
   04014 Ras signaling pathway
    125917114
   04310 Wnt signaling pathway
    125917114
   04668 TNF signaling pathway
    125917114
   04068 FoxO signaling pathway
    125917114
   04071 Sphingolipid signaling pathway
    125917114
   04024 cAMP signaling pathway
    125917114
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    125917114
   04137 Mitophagy - animal
    125917114
  09143 Cell growth and death
   04210 Apoptosis
    125917114
   04215 Apoptosis - multiple species
    125917114
   04217 Necroptosis
    125917114
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    125917114
   04530 Tight junction
    125917114
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    125917114
   04621 NOD-like receptor signaling pathway
    125917114
   04622 RIG-I-like receptor signaling pathway
    125917114
   04625 C-type lectin receptor signaling pathway
    125917114
   04660 T cell receptor signaling pathway
    125917114
   04658 Th1 and Th2 cell differentiation
    125917114
   04659 Th17 cell differentiation
    125917114
   04657 IL-17 signaling pathway
    125917114
   04664 Fc epsilon RI signaling pathway
    125917114
  09152 Endocrine system
   04910 Insulin signaling pathway
    125917114
   04920 Adipocytokine signaling pathway
    125917114
   04912 GnRH signaling pathway
    125917114
   04914 Progesterone-mediated oocyte maturation
    125917114
   04917 Prolactin signaling pathway
    125917114
   04926 Relaxin signaling pathway
    125917114
   04935 Growth hormone synthesis, secretion and action
    125917114
  09156 Nervous system
   04728 Dopaminergic synapse
    125917114
   04723 Retrograde endocannabinoid signaling
    125917114
   04722 Neurotrophin signaling pathway
    125917114
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    125917114
  09158 Development and regeneration
   04380 Osteoclast differentiation
    125917114
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    125917114
   05208 Chemical carcinogenesis - reactive oxygen species
    125917114
   05231 Choline metabolism in cancer
    125917114
  09162 Cancer: specific types
   05210 Colorectal cancer
    125917114
   05212 Pancreatic cancer
    125917114
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    125917114
   05170 Human immunodeficiency virus 1 infection
    125917114
   05161 Hepatitis B
    125917114
   05171 Coronavirus disease - COVID-19
    125917114
   05162 Measles
    125917114
   05167 Kaposi sarcoma-associated herpesvirus infection
    125917114
   05169 Epstein-Barr virus infection
    125917114
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    125917114
   05135 Yersinia infection
    125917114
   05133 Pertussis
    125917114
   05152 Tuberculosis
    125917114
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    125917114
   05142 Chagas disease
    125917114
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    125917114
   05012 Parkinson disease
    125917114
   05016 Huntington disease
    125917114
   05017 Spinocerebellar ataxia
    125917114
   05020 Prion disease
    125917114
   05022 Pathways of neurodegeneration - multiple diseases
    125917114
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    125917114
   05418 Fluid shear stress and atherosclerosis
    125917114
   05415 Diabetic cardiomyopathy
    125917114
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    125917114
   04936 Alcoholic liver disease
    125917114
   04932 Non-alcoholic fatty liver disease
    125917114
   04931 Insulin resistance
    125917114
   04933 AGE-RAGE signaling pathway in diabetic complications
    125917114
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    125917114
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:puc01001]
    125917114
Enzymes [BR:puc01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.24  mitogen-activated protein kinase
     125917114
Protein kinases [BR:puc01001]
 Serine/threonine kinases: CMGC group
  MAPK family [OT]
   125917114
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Kdo ABC1 RIO1 Kinase-like APH FTA2
Other DBs
NCBI-GeneID: 125917114
NCBI-ProteinID: XP_049479332
LinkDB
Position
Unknown
AA seq 344 aa
MSLHLLYYCSEPTLDVKIAFCQGFDKQVDVSYIAKHYNMSKSKVDNQFYSVEVGDSTFTV
LKRYQNLKPIGSGAQGIVCAAYDAVLDRNVAIKKLSRPFQNQTHAKRAYRELVLMKCVNH
KNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIQMELDHERMSYLLYQMLCGIKHL
HSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSFMMTPYVVTRYYRAPEVILGMGY
KENVDIWSVGCIMGEMVRHKILFPGRDYIDQWNKVIEQLGTPCPEFMKKLQPTVRNYVEN
RPKYAGLTFPKLFPDSLFPADSEHNKLKGMSTRDNFRTTVWVMV
NT seq 1035 nt   +upstreamnt  +downstreamnt
atgagcctccatttattgtactactgcagtgaaccaaccttggatgtgaaaattgccttt
tgtcagggattcgataaacaagtggatgtgtcatatattgccaaacattacaacatgagc
aaaagcaaagttgacaaccaattctacagtgtggaagtgggagactcaaccttcacagtt
ctcaagcgctaccagaatttaaagcctattggctctggggctcagggaatagtttgtgct
gcgtatgatgccgttcttgacagaaatgtggccattaagaagctcagcagaccctttcag
aaccaaacgcatgccaagagagcttaccgggagctagtcctcatgaagtgtgtgaaccat
aaaaacattattagtttattaaatgtcttcacaccccagaaaacactggaggagttccag
gatgtttacttagtaatggaactgatggatgccaacttgtgtcaggtgattcagatggaa
ttagaccatgagcgaatgtcttacctgctataccaaatgttgtgtggcatcaagcacctc
cactctgctggaattattcacagggatttaaaaccaagtaacattgtagtcaagtctgat
tgtacattgaaaatcctcgactttggactcgccaggacggcaggcacaagtttcatgatg
actccttatgtggttacccgttattatagagcccctgaggttattctgggaatgggctac
aaggagaacgtggatatatggtctgtgggatgcattatgggagaaatggttcgccacaaa
atcctctttccaggaagggactatattgaccagtggaacaaggtgattgagcaattagga
acgccatgcccagaattcatgaagaaattgcaacccacagtaagaaactatgtggagaat
cggcccaagtatgcaggactcaccttccccaagctctttccagattccctcttcccagcg
gactccgagcacaataaactcaaaggtatgtccaccagggacaatttcagaaccaccgtg
tgggtgatggtctaa

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