Panthera uncia (snow leopard): 125917917 Help Entry 125917917         CDS       T08832                                  Name (RefSeq) son of sevenless homolog 1   KO K03099   son of sevenless Organism puc  Panthera uncia (snow leopard) Pathway puc01521   EGFR tyrosine kinase inhibitor resistance puc01522   Endocrine resistance puc04010   MAPK signaling pathway puc04012   ErbB signaling pathway puc04014   Ras signaling pathway puc04062   Chemokine signaling pathway puc04068   FoxO signaling pathway puc04072   Phospholipase D signaling pathway puc04150   mTOR signaling pathway puc04151   PI3K-Akt signaling pathway puc04510   Focal adhesion puc04540   Gap junction puc04630   JAK-STAT signaling pathway puc04650   Natural killer cell mediated cytotoxicity puc04660   T cell receptor signaling pathway puc04662   B cell receptor signaling pathway puc04664   Fc epsilon RI signaling pathway puc04714   Thermogenesis puc04722   Neurotrophin signaling pathway puc04810   Regulation of actin cytoskeleton puc04910   Insulin signaling pathway puc04912   GnRH signaling pathway puc04915   Estrogen signaling pathway puc04917   Prolactin signaling pathway puc04926   Relaxin signaling pathway puc04935   Growth hormone synthesis, secretion and action puc05034   Alcoholism puc05160   Hepatitis C puc05161   Hepatitis B puc05163   Human cytomegalovirus infection puc05165   Human papillomavirus infection puc05200   Pathways in cancer puc05205   Proteoglycans in cancer puc05206   MicroRNAs in cancer puc05207   Chemical carcinogenesis - receptor activation puc05208   Chemical carcinogenesis - reactive oxygen species puc05210   Colorectal cancer puc05211   Renal cell carcinoma puc05213   Endometrial cancer puc05214   Glioma puc05215   Prostate cancer puc05220   Chronic myeloid leukemia puc05221   Acute myeloid leukemia puc05223   Non-small cell lung cancer puc05224   Breast cancer puc05225   Hepatocellular carcinoma puc05226   Gastric cancer puc05231   Choline metabolism in cancer Brite KEGG Orthology (KO) [BR:puc00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     125917917    04012 ErbB signaling pathway     125917917    04014 Ras signaling pathway     125917917    04630 JAK-STAT signaling pathway     125917917    04068 FoxO signaling pathway     125917917    04072 Phospholipase D signaling pathway     125917917    04151 PI3K-Akt signaling pathway     125917917    04150 mTOR signaling pathway     125917917  09140 Cellular Processes   09144 Cellular community - eukaryotes    04510 Focal adhesion     125917917    04540 Gap junction     125917917   09142 Cell motility    04810 Regulation of actin cytoskeleton     125917917  09150 Organismal Systems   09151 Immune system    04650 Natural killer cell mediated cytotoxicity     125917917    04660 T cell receptor signaling pathway     125917917    04662 B cell receptor signaling pathway     125917917    04664 Fc epsilon RI signaling pathway     125917917    04062 Chemokine signaling pathway     125917917   09152 Endocrine system    04910 Insulin signaling pathway     125917917    04912 GnRH signaling pathway     125917917    04915 Estrogen signaling pathway     125917917    04917 Prolactin signaling pathway     125917917    04926 Relaxin signaling pathway     125917917    04935 Growth hormone synthesis, secretion and action     125917917   09156 Nervous system    04722 Neurotrophin signaling pathway     125917917   09159 Environmental adaptation    04714 Thermogenesis     125917917  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     125917917    05206 MicroRNAs in cancer     125917917    05205 Proteoglycans in cancer     125917917    05207 Chemical carcinogenesis - receptor activation     125917917    05208 Chemical carcinogenesis - reactive oxygen species     125917917    05231 Choline metabolism in cancer     125917917   09162 Cancer: specific types    05210 Colorectal cancer     125917917    05225 Hepatocellular carcinoma     125917917    05226 Gastric cancer     125917917    05214 Glioma     125917917    05221 Acute myeloid leukemia     125917917    05220 Chronic myeloid leukemia     125917917    05211 Renal cell carcinoma     125917917    05215 Prostate cancer     125917917    05213 Endometrial cancer     125917917    05224 Breast cancer     125917917    05223 Non-small cell lung cancer     125917917   09172 Infectious disease: viral    05161 Hepatitis B     125917917    05160 Hepatitis C     125917917    05163 Human cytomegalovirus infection     125917917    05165 Human papillomavirus infection     125917917   09165 Substance dependence    05034 Alcoholism     125917917   09176 Drug resistance: antineoplastic    01521 EGFR tyrosine kinase inhibitor resistance     125917917    01522 Endocrine resistance     125917917 BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  RasGEF RasGEF_N RhoGEF SOS1_NGEF_PH PH PH_19 PH_10 IQ_SEC7_PH RHG20_PH Takusan Motif Other DBs NCBI-GeneID:  125917917 NCBI-ProteinID:  XP_049479948 LinkDB All DBs Position Unknown AA seq 892 aa AA seqDB search MLCQAQPRSASDVEERVQKSFPHPIDKWAIADAQSAIEKRKRRNPLSLPVEKIHPLLKEV LGYKIDHQVSVYIVAVLEYISADILKLVGNYVRNIRHYEITKQDIKVAMCADKVLMDMFH QDVEDINILSLTDEEPSTSGEQTYYDLVKAFMAEIRQYIRELNLIIKVFREPFVSNSKLF SANDVENIFSRIVDIHELSVKLLGHIEDTVEMTDEGSPHPLVGSCFEDLAEELAFDPYES YARDILRPGFHDRFLSQLSKPGAALYLQSIGEGFKEAVQYVLPRLLLAPVYHCLHYFELL KQLEEKSEDQEDKECLKQAITALLNVQSGMEKICSKSLAKRRLSESACRFYSQQMKGKQL AIKKMNEIQKNIDGWEGKDIGQCCNEFIMEGTLTRVGAKHERHIFLFDGLMICCKSNHGQ PRLPGASNAEYRLKEKFFMRKVQINDKDDTSEYKHAFEIILKDENSVIFSAKSAEEKNNW MAALISLQYRSTLERMLDVTMLQEEKEEQMRLPSADVYRFAEPDSEENIIFEENTQPKAG IPIIKAGTVIKLIERLTYHMYADPNFVRTFLTTYRSFCKPQELLSLIIERFEIPEPEPTE ADRIAIENGDQPLSAELKRFRKEYIQPVQLRVLNVCRHWVEHHFYDFERDADLLQRMEEF IGTVRGKAMKKWVESITKIIQRKKIARDNGPGHNITFQSSPPTVEWHISRPGHIETFDLL TLHPIEIARQLTLLESDLYRAVQPSELVGSVWTKEDKEINSPNLLKMIRHTTNLTLWFEK CIVETENLEERVAVVSRIIEILQVFQELNNFNGVLEVVSAMNSSPVYRLDHTFEQIPSRQ KKILEEAHELSEDHYKKYLAKLRSINPPCVPFFGKHFLNFFVFLDKTRYLFH NT seq 2679 nt NT seq  +upstreamnt  +downstreamnt atgctatgccaagctcagccccgaagtgcttcagatgtagaggaacgtgttcaaaaaagt ttccctcatccaattgataagtgggcaatagctgatgcccaatcggctattgaaaagagg aagcgaagaaaccctttatctctcccagtagaaaaaattcatcctttattaaaggaggtc ctaggttataaaattgaccaccaggtttctgtttacatagtagcagtattagaatacatt tctgcagacattttaaagctggtggggaattatgtacgaaatatacggcattatgaaatt acaaaacaagatattaaagtggcaatgtgtgctgataaggtattgatggatatgtttcat caagatgtagaagatataaatattttatctttaaccgatgaagagccttccacctcagga gagcaaacttactatgatttggtaaaagcatttatggcagaaattcgacagtacataagg gaactaaatttaattataaaagtttttagagagccctttgtctccaattcaaaattattt tcagctaatgacgtagaaaatatatttagtcgtatagtagatatacatgaacttagtgta aaattactgggccatatagaagatactgtggaaatgactgatgaaggtagtccccatccc ttagtaggaagctgctttgaagacttagcagaggaactggcatttgatccatatgaatca tatgctcgagatatcttacggcctggttttcatgatcgtttccttagtcagttatcaaag ccaggagcagcactctatttacagtcaataggcgaaggtttcaaagaagctgttcaatat gttttacccaggctacttctagcccctgtttaccactgtctgcattactttgagcttttg aagcagttagaagaaaagagtgaagatcaagaagacaaggaatgtttgaaacaagcaata acagctttgcttaatgttcagagtggtatggaaaaaatatgttctaaaagtcttgcaaaa cgaagactgagtgaatctgcatgtcggttttatagtcagcaaatgaaggggaaacaacta gcaatcaagaaaatgaacgagattcaaaagaatattgatggttgggagggaaaagacatt ggacagtgttgcaatgaatttataatggaaggaactcttacacgtgtaggagccaagcat gagagacacatatttctctttgatggcttaatgatttgctgtaaatcaaatcatgggcag ccaagacttcctggtgctagcaatgcagagtatcgtctgaaagaaaagtttttcatgaga aaggtacaaattaatgacaaagatgacaccagtgagtacaagcatgcttttgaaataatt ttaaaagatgaaaatagtgttatattttctgccaagtcagctgaagagaaaaacaattgg atggcagcactgatatctctccagtaccggagcacactggaaaggatgcttgacgtgacg atgctacaggaagagaaggaggagcagatgaggctccctagtgctgatgtttatcgattt gcagagcctgactccgaagagaatataatatttgaagagaacacacagcccaaggctgga attccaattatcaaagcaggaactgttattaagcttattgagaggctcacgtaccatatg tacgcagatcccaattttgttcggacatttcttacaacatacagatccttttgtaaacct caagaactactgagtcttataatagaaaggtttgaaattccagagcctgagccaacagaa gctgatcgcatagctatagagaatggagatcaacccttgagtgcagaactaaaaaggttt aggaaagaatacatacagcctgtacaactgcgagtattaaatgtatgtcggcattgggta gagcaccatttctatgattttgaaagagacgcagatcttttgcagcgaatggaagagttt attggaacagtaagaggtaaagcaatgaaaaaatgggttgaatccatcactaaaataatc caaaggaaaaaaattgcaagagacaatggaccaggtcataatattacatttcagagttca cctcccacagttgagtggcatataagcaggcctgggcacatagagacttttgacctgctc accttacacccaatagaaattgctcgacaactcactttacttgaatcagatctatatcga gctgtacagccatcagaattagttggaagcgtgtggacaaaagaagacaaagaaattaat tctcctaatctcctaaaaatgatccggcacaccactaacctcactctgtggtttgagaaa tgtattgtagaaactgaaaacttagaagaaagagtagctgtggtgagtcgaataattgag attctacaagtctttcaagagctgaacaatttcaatggtgtccttgaggttgtcagtgct atgaactcatctcctgtttacagactagaccacacatttgagcaaataccaagtcgccaa aagaaaattttagaagaagctcatgagttaagcgaagatcactataagaaatatttggca aaactcaggtctattaatccaccgtgtgtgcctttctttggtaagcatttcttgaatttt tttgtgtttctggataaaacaagatacttatttcattaa

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