Panthera uncia (snow leopard): 125920161
Help
Entry
125920161 CDS
T08832
Name
(RefSeq) inositol 1,4,5-trisphosphate receptor type 2 isoform X1
KO
K04959
inositol 1,4,5-triphosphate receptor type 2
Organism
puc
Panthera uncia (snow leopard)
Pathway
puc04020
Calcium signaling pathway
puc04022
cGMP-PKG signaling pathway
puc04070
Phosphatidylinositol signaling system
puc04114
Oocyte meiosis
puc04210
Apoptosis
puc04218
Cellular senescence
puc04270
Vascular smooth muscle contraction
puc04371
Apelin signaling pathway
puc04380
Osteoclast differentiation
puc04540
Gap junction
puc04611
Platelet activation
puc04621
NOD-like receptor signaling pathway
puc04625
C-type lectin receptor signaling pathway
puc04720
Long-term potentiation
puc04723
Retrograde endocannabinoid signaling
puc04724
Glutamatergic synapse
puc04725
Cholinergic synapse
puc04726
Serotonergic synapse
puc04728
Dopaminergic synapse
puc04730
Long-term depression
puc04750
Inflammatory mediator regulation of TRP channels
puc04912
GnRH signaling pathway
puc04915
Estrogen signaling pathway
puc04918
Thyroid hormone synthesis
puc04921
Oxytocin signaling pathway
puc04922
Glucagon signaling pathway
puc04924
Renin secretion
puc04925
Aldosterone synthesis and secretion
puc04927
Cortisol synthesis and secretion
puc04928
Parathyroid hormone synthesis, secretion and action
puc04929
GnRH secretion
puc04934
Cushing syndrome
puc04935
Growth hormone synthesis, secretion and action
puc04970
Salivary secretion
puc04971
Gastric acid secretion
puc04972
Pancreatic secretion
puc05010
Alzheimer disease
puc05012
Parkinson disease
puc05017
Spinocerebellar ataxia
puc05020
Prion disease
puc05022
Pathways of neurodegeneration - multiple diseases
puc05163
Human cytomegalovirus infection
puc05167
Kaposi sarcoma-associated herpesvirus infection
puc05170
Human immunodeficiency virus 1 infection
puc05205
Proteoglycans in cancer
Brite
KEGG Orthology (KO) [BR:
puc00001
]
09130 Environmental Information Processing
09132 Signal transduction
04371 Apelin signaling pathway
125920161
04020 Calcium signaling pathway
125920161
04070 Phosphatidylinositol signaling system
125920161
04022 cGMP-PKG signaling pathway
125920161
09140 Cellular Processes
09143 Cell growth and death
04114 Oocyte meiosis
125920161
04210 Apoptosis
125920161
04218 Cellular senescence
125920161
09144 Cellular community - eukaryotes
04540 Gap junction
125920161
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
125920161
04621 NOD-like receptor signaling pathway
125920161
04625 C-type lectin receptor signaling pathway
125920161
09152 Endocrine system
04922 Glucagon signaling pathway
125920161
04929 GnRH secretion
125920161
04912 GnRH signaling pathway
125920161
04915 Estrogen signaling pathway
125920161
04921 Oxytocin signaling pathway
125920161
04935 Growth hormone synthesis, secretion and action
125920161
04918 Thyroid hormone synthesis
125920161
04928 Parathyroid hormone synthesis, secretion and action
125920161
04924 Renin secretion
125920161
04925 Aldosterone synthesis and secretion
125920161
04927 Cortisol synthesis and secretion
125920161
09153 Circulatory system
04270 Vascular smooth muscle contraction
125920161
09154 Digestive system
04970 Salivary secretion
125920161
04971 Gastric acid secretion
125920161
04972 Pancreatic secretion
125920161
09156 Nervous system
04724 Glutamatergic synapse
125920161
04725 Cholinergic synapse
125920161
04728 Dopaminergic synapse
125920161
04726 Serotonergic synapse
125920161
04720 Long-term potentiation
125920161
04730 Long-term depression
125920161
04723 Retrograde endocannabinoid signaling
125920161
09157 Sensory system
04750 Inflammatory mediator regulation of TRP channels
125920161
09158 Development and regeneration
04380 Osteoclast differentiation
125920161
09160 Human Diseases
09161 Cancer: overview
05205 Proteoglycans in cancer
125920161
09172 Infectious disease: viral
05170 Human immunodeficiency virus 1 infection
125920161
05163 Human cytomegalovirus infection
125920161
05167 Kaposi sarcoma-associated herpesvirus infection
125920161
09164 Neurodegenerative disease
05010 Alzheimer disease
125920161
05012 Parkinson disease
125920161
05017 Spinocerebellar ataxia
125920161
05020 Prion disease
125920161
05022 Pathways of neurodegeneration - multiple diseases
125920161
09167 Endocrine and metabolic disease
04934 Cushing syndrome
125920161
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04040 Ion channels [BR:
puc04040
]
125920161
Ion channels [BR:
puc04040
]
Ligand-gated channels
IP3 receptor
125920161
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Ins145_P3_rec
RYDR_ITPR
MIR
RIH_assoc
Ion_trans
C_GCAxxG_C_C
Motif
Other DBs
NCBI-GeneID:
125920161
NCBI-ProteinID:
XP_049483133
LinkDB
All DBs
Position
B4:complement(57936531..58427254)
Genome browser
AA seq
2701 aa
AA seq
DB search
MSDKMSSFLYIGDIVSLYAEGSVNGFISTLGLVDDRCVVHPEAGDLANPPKKFRDCLFKV
CPMNRYSAQKQYWKAKQAKQGNHTEAALLKKLQHAAELEQKQNESENKKLLGEIVKYSNV
IQLLHIKSNKYLTVNKRLPALLEKNAMRVSLDAAGNEGSWFYIHPFWKLRSEGDNIVVGD
KVVLMPVNAGQPLHASNIELLDNPGCKEVNAVNCNTSWKITLFMKYSSYREDVLKGGDVV
RLFHAEQEKFLTCDEYEKKQHIFLRTTLRQSATSATSSKALWEIEVVHHDPCRGGAGQWN
SLFRFKHLATGNYLAAELNPDYRDAQNEGKTVRDGDLPTSKKKRQAGEKIMYTLVSVPHG
NDIASLFELDATTLQRADCLVPRNSYVRLRHLCTNTWVTSTSIPIDTDEERPVMLKIGTC
QTKEDKEAFAIVSVPLSEVRDLDFANDANKVLATTVKKLENGTITQNERRFVTKLLEDLI
FFVADVLNNGQEVLDVVIIKPNRERQKLMREQNILAQVFGILKAPFKEKAGEGSMLRLED
LGDQRYAPYKYMLRLCYRVLRHSQQDYRKNQEYIAKNFCVMQSQIGYDILAEDTITALLH
NNRKLLEKHITAKEIETFVSLLRRNREPRFLDYLSDLCVSNTTAIPVTQELICKFMLSPG
NADILIQTKLVSMQVDNPLESAILSDDIDDEEVWLYWIDSNKEPHGKAIRHLAQEAKEGT
KADLEVLTYYRYQLNLFARMCLDRQYLAINQISTQLSVDLILRCVSDESLPFDLRASFCR
LMLHMHVDRDPQESVVPVRYARLWTEIPTKITIHEYDSITDSSRNDMKRKFALTMEFVEE
YLKEVVNQPFPFGDKEKNKLTFEVVHLARNLIYFGFYSFSELLRLTRTLLAILDIIQVPM
SSYFERLSKFQDGGNNVMRTIHGVGEMMTQMVLSRGSIFPMSVPDVQPSIHPSKQGSPVE
PEDVTVMDTKLKIIEILQFILSVRLDYRISYMLSIYKKEFGENNENAEASASGSPDTLLP
SAIVPDIDEIAAQAETMFAGRKEKNPVQLDDEGGRTFLRVLIHLIMHDYPPLLSGALQLL
FKHFSQRAEVLQAFKQVQLLVSNQDVDNYKQIKADLDQLRLTVEKSELWVEKSSSYENGE
MGESQVKGGEEPIEESSILSPVQDGTRKPQIDSNRGNNYRIVKEILIRLSKLCVQNKKCR
NQHQRLLKNMGAHSVVLDLLQIPYEKNDEKMNEVMHLAHTFLQNFCRGNPQNQVLLHKHL
NLFLTPGLLEAETMRHIFMNNYHLCNEISERVVQHFVHCIETHGRHVEYLRFLQTIVKAD
GKYVKKCQDMVMTELINGGEDVLIFYNDRASFPILLHMMCSERDRGDESGPLAYHITLVE
LLAACTEGKNVYTEIKCNSLLPLDDIVRVVTHDDCIPEVKIAYVNFVNHCYVDTEVEMKE
IYTSNHIWKLFENFLVDMARVCNTTTDRKHADIFLEKCVTESVMNIVSGFFNSPFSDNST
SLQTHQPVFIQLLQSAFRIYNCTWPNPAQKSSVESCIRTLAEVAKNRGIAIPVDLDSQVN
TLFLKSHSNMVQRAAMGWRLSARSGPRFKEALGGPAWDYRNIIEKLQDVVASLEQQFSPM
MQAEFSVLVDVLYSPELLFPEGSDARIRCGAFMSKLINHTKKLMEKEEKLCIKILQTLRE
MLEKKDSFVEEGNTLRKILLNRYFKGDYGVGINGHLSGTYSKSAQGGGSFSGQDSDKMGI
SMSDIQCLLDKEGASELVIDVIVNTKNDRIFSEGILLGIALLEGGNTQTQYSFYQQLHEQ
KKSEKFFKVLYDRMKAAQKEIRSTVTVNTIDLGNKKRDDDNELMTSGPRMRVRDSSLLLK
EGMKGQLTEASSATSKAYCAYRREMDPEIDMMCAGSEAGNAEEKSAEEVTMSPAIAIMQP
ILRFLQLLCENHNRELQNFLRNQNNKTNYNLVCETLQFLDCICGSTTGGLGLLGLYINEK
NVVLVNQTLESLTEYCQGPCHENQTCIATHESNGIDIIIALILNDINPLGKYRMDLVLQL
KNNASKLLLAIMESRHDSENAERILFNMRPRELVDVMKNAYNQGLECDHGDDDGGDDGVS
PKDVGHNIYILAHQLARHNKLLQQMLKPGSDPDDGDEALKYYANHTAQIEIVRHDRTMEQ
IVFPVPNICEYLTRESKSRVFNTTERDEQGSKVNDFFQQTEDLYNEMKWQKKIRSNPALF
WFSRHISLWGSISFNLAVFINLAVALFYPFGDDGDEGTLSPLFSVLLWIAVAICTSMLFF
FSKPVGIRPFLVSVMLRSIYTIGLGPTLILLGAANLCNKIVFLVSFVGNRGTFTRGYRAV
ILDMAFLYHVAYVLVCMLGLFVHEFFYSFLLFDLVYREETLLNVIKSVTRNGRSIILTAV
LALILVYLFSIIGFLFLKDDFTMEVDRLKNRTPVTGSNEVPTMTLTSMMGTCEKDNCSPT
IPASNTADEEYEDGIERTCDTLLMCIVTVLNQGLRNGGGVGDVLRRPSKDEPLFAARVVY
DLLFYFIVIIIVLNLIFGVIIDTFADLRSEKQKKEEILKTTCFICGLERDKFDNKTVSFE
EHIKSEHNMWHYLYFLVLVKVKDPTEYTGPESYVAQMIVEKNLDWFPRMRAMSLVSNEGD
SEQNEIRNLQEKLESTMSLVKQLSGQLAELKEQMTEQRKNKQRLGFLGSNTPHVNHHMPP
H
NT seq
8106 nt
NT seq
+upstream
nt +downstream
nt
atgtctgataaaatgtccagcttcctctacataggggacatcgtgtccctgtacgcggag
ggctcggtcaacggcttcatcagcaccctggggttagtggatgacagatgtgtggtgcac
ccggaggcgggagaccttgcgaaccctcccaagaaattcagagactgcctctttaaggtg
tgccctatgaaccgatattctgcccagaaacaatattggaaagctaagcaagccaaacag
gggaaccacacagaggcagccttgctgaagaaattacagcatgctgcagaactggaacaa
aaacaaaatgaatcagagaataagaaactgttgggagaaattgtgaagtacagtaatgtt
atacaactgctacatataaaaagcaacaagtatctgactgtcaacaagagattacctgct
ttattggagaagaacgccatgcgtgtgtccttggatgctgccggaaatgaagggtcttgg
ttttatattcatcccttctggaagctgagaagcgagggtgacaatattgtcgtaggcgac
aaagttgttttgatgcccgtgaatgcaggacaaccactgcatgccagcaacatagagctt
ctggataatccagggtgtaaagaggtgaatgctgttaattgcaacacgagctggaaaatc
actttatttatgaaatatagttcctatcgagaggatgtactaaaaggaggtgatgttgtt
agattgtttcatgcagaacaagagaagtttctgacttgcgatgaatatgagaaaaaacaa
cacattttccttcgtacaaccttgcgtcaatcagccacttctgctactagttctaaagca
ctctgggaaatagaggtagttcatcatgacccttgccgtggcggtgctggacaatggaac
agcttgttcagatttaaacaccttgcaactgggaactatttagctgcagagcttaatcct
gattatcgagatgctcaaaatgaaggaaaaactgtgagagatggagatcttccaacttca
aagaagaaacgccaggcaggggaaaagatcatgtacactttagtctcagtaccccatgga
aatgatattgcatccctctttgaactggatgccacaactcttcagagagctgactgcctg
gtcccaaggaactcatacgttcggttaaggcatttatgtaccaacacgtgggtaacaagt
accagtatccccatagacacagatgaagagaggcctgttatgttaaagattggaacctgc
caaacaaaagaagataaagaagcatttgccattgtgtctgtcccgctgtctgaggtccga
gacttagactttgccaatgatgcaaataaagtgctggcgaccacagttaaaaagctggaa
aatggtacaataactcagaatgaaaggaggtttgtaaccaaattattagaagacctcatc
ttctttgtggctgatgtacttaataacggacaagaagttttggatgttgttatcattaag
ccaaaccgagaacgtcaaaagttaatgagggaacaaaacatactggcacaggtatttggg
attcttaaagcaccctttaaggagaaagcaggagaaggctcaatgttgagacttgaagat
ctgggggaccaaagatacgctccttataagtacatgctgaggctgtgttaccgcgtgctc
agacattcgcagcaggactacaggaaaaatcaggaatatattgctaagaatttctgtgtc
atgcagtcccagattggctatgatattttggcagaagataccatcacagctttgttgcac
aacaacagaaaactactagagaaacatatcacagcaaaagaaatagaaacatttgtcagt
ttactcaggagaaatcgcgagccaagatttttggattatttatcagatctgtgtgtgtct
aatactactgctatacctgtaactcaagaactcatctgtaaatttatgttgagcccaggc
aatgcagacattctcattcaaactaagctggtctcaatgcaagtagacaaccccctggag
agcgccatcctttcagatgacattgatgatgaagaagtttggctctactggattgacagc
aacaaggaacctcacggcaaagctatcagacaccttgcacaagaagcgaaagagggcacc
aaggctgatttggaagttcttacctattacaggtaccagctaaacctctttgcaaggatg
tgcttagatcgccagtatctggccataaaccagatttctacgcagctctctgttgatttg
atcctgcggtgtgtgtcggatgagagcctgccatttgacctccgagcgtctttttgtcgc
ctcatgctccacatgcatgttgaccgggatccccaggagtctgtggtacctgttcgctat
gccaggctctggacagaaatccccacaaagatcacaattcatgaatatgattctataaca
gactcttccagaaatgatatgaagaggaaatttgcactgacaatggaatttgttgaagaa
tacttgaaagaagttgtaaatcagccctttccttttggggataaagaaaaaaacaaactg
acatttgaggtggtccacttggctcggaatcttatatactttggattttatagcttcagt
gaattgctaaggctaacaagaacacttctggctatcctagatattatacaggtccccatg
tcatcgtattttgaaagattgagcaaatttcaagatggaggaaacaatgtcatgagaacc
atccatggggtgggagagatgatgacccaaatggtactcagtagaggctctatctttccc
atgagtgtgcctgacgttcagcccagcatccaccccagcaagcaaggaagccctgtagag
cctgaggacgtgaccgtgatggacaccaaactgaagattattgagattttacagtttatc
ctgagtgtcagactggattataggatctcatatatgctgtcaatatataagaaggaattt
ggagagaataatgaaaacgctgaagcatctgccagtggctctccagatacattactacca
tcagcgattgttcctgatatagatgaaatcgcagctcaggcagaaacgatgtttgctgga
agaaaggagaaaaatccagttcaacttgatgatgaaggaggcaggacatttttacgggtc
ctcattcatctgatcatgcacgactacccgcctctgctatcaggggccctgcaactactg
ttcaagcactttagccagagagccgaagttttacaggcatttaaacaggtgcaattgctg
gtgtccaatcaagatgtagataactacaagcagatcaaggcggatctagaccagcttcga
ctcactgtagaaaaatctgagttatgggttgagaagagcagcagctatgagaatggagaa
atgggtgaaagtcaagtaaaaggtggtgaagagccaattgaggaatcaagcattttaagc
ccagtgcaggatggaacaaggaaacctcagattgacagcaataggggtaataactaccgg
atcgtgaaggagattttgattagactaagtaaactctgtgtacagaataaaaagtgtcgg
aatcaacatcaacgattactgaaaaatatgggagcccattcggtggtgttggatcttctg
cagataccctatgaaaagaatgacgaaaagatgaatgaagtgatgcatctggcccacaca
ttcctgcagaatttctgtcggggaaatccacagaaccaagttctccttcacaaacatctc
aatttgtttttaactcctggtctccttgaagcagaaaccatgcggcacatcttcatgaac
aattaccatctctgcaatgagatcagcgagagggtagtacaacactttgtgcactgcatt
gagacacatggccgccacgtggagtacctgaggtttttgcaaacgattgtaaaagcagat
ggcaaatatgtgaagaaatgccaggatatggtaatgacagagttgataaatgggggtgaa
gatgtgctgatattttacaatgatagagcctcatttcccatccttctccatatgatgtgt
tcagagagagaccgaggggatgagagtggccccttagcttaccacatcacgctggtggag
ctgctggcagcatgtacagaggggaaaaatgtctacactgaaatcaagtgcaattccctt
ctgcccttggacgacatagtaagggtggtgacccatgatgactgcatccctgaggttaaa
attgcttatgtgaatttcgttaatcactgttatgtggacacagaagtggaaatgaaagaa
atctacacaagtaaccacatttggaagttatttgagaacttcttggtggatatggcaagg
gtttgtaacacaaccacagacaggaaacatgcagacatcttcttggagaagtgtgttacc
gagtcagtaatgaacatcgtgagcggcttctttaattccccattttcagacaacagtacc
agcctccagacacatcagccagtttttattcagctgcttcaatctgccttcaggatttac
aattgcacctggccaaatccagcacagaaatcatctgtggagtcttgtatcagaactttg
gctgaagtggcaaagaatcgcgggattgccattccagtggatttggacagccaagtgaat
actcttttcctgaagagccattctaatatggtgcagagagcagctatgggttggagacta
tctgctcgctctggaccacgttttaaggaagctcttggagggcctgcttgggattataga
aacatcattgaaaagttacaggatgttgtggcctccttggaacaacagttcagcccaatg
atgcaggctgagttctcggtgttggttgatgtgttgtatagtccagaactactgttccct
gaggggagtgatgcaagaataagatgcggtgctttcatgtccaagttgattaatcataca
aagaaactgatggagaaggaagaaaagttgtgcattaaaattctccagactttacgagaa
atgctagagaagaaagacagctttgtggaagagggcaacacattaagaaaaatactcctg
aatcgctactttaaaggagactatggagttggtatcaatggacacctctctggaacctac
agcaaatctgcacaagggggagggagcttttcgggacaagattcagataagatggggata
tcaatgtcagatattcagtgtctactggataaagaaggtgcatctgaacttgtcattgat
gttatagtgaacaccaaaaatgacagaattttttcagaaggaattttacttggcattgcc
ttgctcgaaggaggaaatacacaaactcagtactccttctaccagcaattacatgaacaa
aaaaagtcagaaaaattcttcaaagttctgtatgaccgaatgaaggctgctcagaaagag
ataagatcaacagtgaccgttaataccatagacttaggtaacaaaaaaagggatgatgac
aatgaattgatgacatctggtccacgaatgagagtgagagattcatcattacttttaaaa
gagggaatgaaagggcaattaacagaagcttcttcggcaacctccaaagcgtattgtgct
taccgaagagaaatggatccagaaatcgacatgatgtgtgcaggatccgaagcaggaaat
gccgaggaaaagtctgccgaggaagtaaccatgagtcctgcaattgccatcatgcagccc
atactgaggtttctgcagttgctgtgtgagaatcacaaccgggagctgcagaacttcttg
aggaatcaaaacaacaaaacaaattataaccttgtctgtgagacccttcagtttttggac
tgcatttgtggaagtaccaccggtggcctgggcctattgggtctctacatcaatgagaag
aatgtagtgctggtcaaccagactctggagagcttgacggagtattgccagggcccatgc
catgaaaatcagacgtgtattgctactcatgaatccaatgggattgatatcatcattgct
ttgattctaaatgacataaaccctcttggaaaatatcgaatggatctggtgctccaacta
aagaacaatgcctccaagcttttgctggccatcatggaaagcagacacgacagtgagaat
gcggaaagaattctttttaacatgagacccagagaactggtggatgtgatgaagaacgcc
tataaccaaggattggaatgtgaccatggggatgatgatggaggagatgacggtgtttcc
ccaaaagatgttggacacaatatctatattctggcccatcagttggcccgtcacaacaaa
ctcttacaacagatgctcaaaccaggatcagatccagatgatggggatgaagccttaaaa
tattatgccaatcacactgcacagattgagattgttcggcatgataggacaatggaacaa
atagtttttcctgtccccaatatatgtgaataccttacgcgagaatccaagagccgtgtg
ttcaacacaactgaaagggatgaacaaggaagtaaagtgaatgactttttccagcaaact
gaagatctctacaatgaaatgaagtggcagaagaaaatcaggagtaaccctgccctgttc
tggttctcaaggcacatatccctgtgggggagcatttccttcaacttggctgtgttcatc
aatttagctgttgctctcttctacccatttggggatgatggagatgaaggtacgctttcc
ccgttgttctcagttctactttggatagcagttgcaatctgcacatcgatgctatttttc
ttctccaagcctgtgggtattcggccatttcttgtgtcagtaatgctcagatcaatatat
acaataggtcttgggcctacattaatacttcttggtgcagctaatctttgtaataaaata
gtgtttctggtgagttttgtgggaaatcgtggcactttcacccgaggctaccgagcggtc
atcctggatatggcctttctctaccacgtggcatatgtcctggtttgcatgctgggcctc
tttgtccatgaattcttctatagcttcctgctgtttgatttggtgtacagagaagagact
ctgctcaatgtcataaagagtgtcacacggaatggccgctccattattctaactgcagtc
ctggctctcatccttgtctacctgttttccattattggattcctttttctgaaggatgac
ttcacaatggaagtggataggctgaaaaacagaactcccgttacagggagtaatgaagtt
cctactatgactttaacttcaatgatgggaacatgtgaaaaggacaactgctcacccaca
ataccagcttcaaatacagcagatgaagagtatgaagatggaattgaaaggacgtgtgac
acgctccttatgtgcattgtcactgtcctgaaccagggcctcaggaatggcggcggcgtg
ggagatgttctgagaaggccatcgaaagatgagcccttgtttgctgcccgagtggtatat
gaccttcttttttatttcattgttatcatcatcgttcttaacttgatttttggtgttatc
attgatacttttgctgatctcagaagtgaaaaacagaaaaaggaagaaattctaaagaca
acatgtttcatctgtggacttgagagggacaagtttgataacaaaactgtttcatttgag
gaacacatcaagtcagaacacaacatgtggcattatttgtacttcctagtcctggtgaag
gttaaagaccccactgaatacactgggcctgaaagttatgtggctcaaatgattgtggag
aagaatttagactggtttcctcggatgcgagccatgtccctcgtcagcaatgaaggtgac
agcgagcaaaatgagattcggaacctgcaggagaagttggaatccaccatgagtctggtc
aaacagctgtctggtcagctagcagagctcaaggagcagatgacagaacaaaggaagaat
aagcagagactgggctttctcggatcaaacacaccccatgtgaatcatcacatgccacca
cactga
DBGET
integrated database retrieval system
