Panthera uncia (snow leopard): 125921703
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Entry
125921703 CDS
T08832
Name
(RefSeq) trifunctional purine biosynthetic protein adenosine-3
KO
K11787
phosphoribosylamine--glycine ligase / phosphoribosylglycinamide formyltransferase / phosphoribosylformylglycinamidine cyclo-ligase [EC:
6.3.4.13
2.1.2.2
6.3.3.1
]
Organism
puc
Panthera uncia (snow leopard)
Pathway
puc00230
Purine metabolism
puc00670
One carbon pool by folate
puc01100
Metabolic pathways
puc01523
Antifolate resistance
Module
puc_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
puc00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
125921703
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
125921703
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
125921703
Enzymes [BR:
puc01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.2 phosphoribosylglycinamide formyltransferase 1
125921703
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.3 Cyclo-ligases
6.3.3.1 phosphoribosylformylglycinamidine cyclo-ligase
125921703
6.3.4 Other carbon-nitrogen ligases
6.3.4.13 phosphoribosylamine---glycine ligase
125921703
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
GARS_A
Formyl_trans_N
AIRS_C
GARS_N
GARS_C
AIRS
ATP-grasp
ATP-grasp_3
ATP-grasp_2
CPSase_L_D2
ATP-grasp_4
Dala_Dala_lig_C
CbiJ
RimK
Motif
Other DBs
NCBI-GeneID:
125921703
NCBI-ProteinID:
XP_049485230
LinkDB
All DBs
Position
C2:11161954..11193368
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AA seq
1009 aa
AA seq
DB search
MAARVLVIGGGGREHTLAWKLAQSNRVKHVLVAPGNAGTACLEKISNTAISISDHTALAQ
FCKDENIEFVVVGPEAPLAAGIVGNLTSAGVRCFGPTAEAAQLESSKRFAKEFMDRHGIP
TARWRAFTRPEEACSFIMSADFPALVVKASGLAAGKGVIVAKSTEEACRAVQEIMQEKAY
GAAGETIVIEELLEGEEVSCLCFTDGKTVAPMPPAQDHKRLLEGDHGPNTGGMGAYCPAP
QVSKDLLLKIKNTVLQRTVDGMQQEGMPYTGVLYAGIMLTKDGPKVLEFNCRFGDPECQV
ILPLLKSDLYEVIQSTFDGLLHTSLPVWLENRTALTVVMASKGYPGDYTKGVEITGFPEA
QALGLEVFHAGTALKDGKVVTSGGRVLSVTAIQENLISALEEAKKGLAAIKFEGAIYRKD
IGSRAIAYLQQPRGLTYKKSGVDIAAGNMLVKKIKPLAKATSRPGCDVDLGGFAGLFDLK
AAGFKDPLLACGTDGVGTKLKIAQQCNRHDTIGQDLVAMCVNDILAQGAEPLFFLDYFSC
GKLDLDTTEAVVAGIARACGKAGCALLGGETAEMPDMYPPGEYDLAGFAVGAMERDQKLP
HLERITEGDVVIGIASSGLHSNGFSLVRKIVAKSSLQYSSPAPDGCGDQTLGDLLLTPTR
IYSHSLLPVLRSGHVKVFAHITGGGLLENIPRVLPEKFGVDLDAQTWRIPRIFSWLQQEG
HLSEEEMARTFNCGVGAVLVVSKDRTEQILRDIKQHSEEAWVIGKVVACPEGSPRVKVKH
LIETMQANGSVLENGTLKNHFSVQPKKARVAVLISGTGSNLQALIDNTREPSSCAHIVVV
ISNKAAVAGLDKAERAGIPTRVINHKLYKSRVEFDTAIDQVLEEFSTDIVCLAGFMRILS
GPFVRKWNGKMLNIHPSLLPSFKGSNAHEQVLEAGVTVTGCTVHFVAEDVDAGQIILQEA
VPVKRGDTITTLSERVKLAEHKLFPAALQLVASGTVQLGENGKIRWVTE
NT seq
3030 nt
NT seq
+upstream
nt +downstream
nt
atggcagcccgcgtacttgtaattggcggtggcggaagggaacatacactggcttggaaa
cttgcacagtctaatcgtgtcaaacatgtgttggttgccccgggcaatgcaggcactgcc
tgcttggaaaagatttcaaatactgccatctcgataagtgatcacactgcccttgctcag
ttctgcaaagatgagaacattgaattcgtagttgttggaccagaggcacctctggctgct
ggaattgttgggaacctgacctctgcaggagtgcgatgctttggtcccacagcagaagca
gctcagttagagtccagcaagagatttgccaaagagtttatggaccgacacggaatcccg
accgcacggtggagagctttcaccagacctgaggaggcctgcagcttcattatgagtgca
gacttccctgctttggttgtgaaggccagtggtcttgcagctgggaaaggggtgattgtt
gcaaagagcacagaagaagcctgcagggctgtacaggagatcatgcaggagaaagcttat
ggagcagctggagaaacaattgtcattgaagaacttcttgaaggagaagaggtttcttgt
ctgtgcttcactgatggcaagaccgtggcccccatgcccccagcacaagaccataaacga
ttgctggagggcgatcacggccccaacacagggggaatgggagcctattgtccggcacct
caggtttcgaaggatttgctgctgaaaataaaaaatacagttcttcagaggacagtggat
ggcatgcagcaggagggtatgccatacacaggtgtcctctatgctggtataatgctgacc
aaggatggcccaaaagttctggagtttaattgccgtttcggtgatccagagtgccaagtg
atcctcccgctgcttaaaagtgatctttatgaagtgattcagtctacctttgatggcctg
ctccacacatctctgcctgtctggctggaaaaccgcaccgccctaactgttgtgatggca
agtaagggctacccaggagattacaccaagggtgtggagataacaggctttcctgaggct
caagctttaggactggaggtgttccacgcaggcaccgccctgaaagatggcaaagtggtg
actagtgggggtagagtcctttcggtaacagccatccaggaaaatctcatttcagccctt
gaagaagccaagaaaggactagctgctataaaatttgagggagccatttacaggaaggac
attggctctcgtgccatagcttatctccaacagcccaggggcctgacttacaagaaatct
ggggtagacattgcagctggaaatatgctggtcaagaaaattaaacctttagcaaaagct
acctccagaccaggctgtgatgttgatcttggaggttttgctggtctttttgatttgaaa
gcagctggtttcaaagatcctcttctggcctgtggaacagatggtgtggggactaaactg
aagattgcccagcagtgtaatagacatgataccattggccaagatttggttgcaatgtgt
gtaaatgacattctggcccaaggggcagagcccctcttcttccttgattacttttcctgt
ggaaaacttgacctcgatacaactgaagctgttgttgctggaattgccagagcctgtggg
aaagctggatgtgctctccttggaggtgaaactgcagaaatgcctgacatgtatcctcct
ggagagtatgacctggccggttttgccgtcggtgccatggagcgggatcagaaactccct
cacctggaaagaatcaccgaaggggatgttgttattggaatagcttcatctggtcttcac
agcaatggatttagccttgtgaggaaaattgtagcaaaatcttccctccagtactcctct
ccagcacctgatggctgtggtgaccagaccttaggggacttacttctgactccaacgaga
atctacagccattcgctattacctgtcctacgttcaggacatgtcaaggtctttgcccat
attactggtggaggattgctagaaaacatccccagagtccttcctgagaaatttggagtg
gatttagatgcccagacctggaggatccccaggatcttctcgtggttacagcaagaagga
cacctctctgaggaagagatggccagaacatttaactgtggggttggggccgtcctcgtg
gtgtcaaaggataggacagagcagattctgagggatatcaagcagcacagcgaagaagcc
tgggtgattggcaaggtggttgcgtgtcctgaaggttctcctcgtgtgaaagtcaagcat
ctgattgaaaccatgcaagcaaatggatcagtattggagaatggcactctgaaaaatcat
ttctctgtccaaccaaaaaaggcaagagtggctgtcttaatatctggaacaggatcaaac
ctccaagccctcatagacaatactagggagccaagtagctgtgcacacattgttgttgtt
atctccaacaaagctgcagtggctggcttagataaagcagaaagagccggaattcccacc
agagtaatcaatcataaattatataaaagtcgtgtagaatttgacactgcaattgaccaa
gtccttgaagagttctccacagacatagtctgtcttgcaggattcatgagaattttatct
ggcccctttgtcagaaaatggaatgggaaaatgctcaacatccatccatccttgctgccg
tcttttaagggttcaaatgcacatgagcaagtcctagaagccggggtcacagtcactggg
tgtactgtgcactttgtagctgaagatgtagatgctggacagattatcttacaagaagct
gttccagtgaagaggggcgacaccattacaactctgtctgaaagagtgaaattagcagag
cacaaactatttcccgcagccctccagctggtagccagtggaactgtacagcttggagaa
aatggcaagattcgttgggtcacagagtag
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