Panthera uncia (snow leopard): 125924165
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Entry
125924165 CDS
T08832
Name
(RefSeq) serine/threonine-protein kinase WNK2
KO
K08867
WNK lysine deficient protein kinase [EC:
2.7.11.1
]
Organism
puc
Panthera uncia (snow leopard)
Pathway
puc04928
Parathyroid hormone synthesis, secretion and action
Brite
KEGG Orthology (KO) [BR:
puc00001
]
09150 Organismal Systems
09152 Endocrine system
04928 Parathyroid hormone synthesis, secretion and action
125924165
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
puc01001
]
125924165
01009 Protein phosphatases and associated proteins [BR:
puc01009
]
125924165
Enzymes [BR:
puc01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
125924165
Protein kinases [BR:
puc01001
]
Serine/threonine kinases: Other
Wnk family
125924165
Protein phosphatases and associated proteins [BR:
puc01009
]
Protein serine/threonine phosphatases
Phosphoprotein phosphatases (PPPs)
Protein phosphatase-1
PP1-interacting proteins (PIPs)
125924165
BRITE hierarchy
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
CCTL2_WNK
OSR1_C
Motif
Other DBs
NCBI-GeneID:
125924165
NCBI-ProteinID:
XP_049488628
LinkDB
All DBs
Position
D4:1047112..1183573
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AA seq
2180 aa
AA seq
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MSLMSVKISGAVVHVHRGSFGSDFVEHKSCQPPPEELRDDTAVWPAWVPAREASLHEPAA
SGAFRSPRGPGAPRPPPQAGPQVAARAHGQVGVPGPALPARRQGAGSRGPALPARRVGAG
ARAQQSRAGAARGSAVPQRAGRESSAETRPRARTPASSTTRPPRPPARTPAPESGLARLA
RPGRRAAGMDGARSPCECRAPRPPPLCARRAAAAPSPRAPPAPRAASFVEPPPGRWGDGR
FLKFDIELGRGSFKTVYKGLDTETWVEVAWCELQDRKLTKLERQRFKEEAEMLKGLQHPN
IVRFYDFWESSARGKRCIVLVTELMTSGTLKTYLKRFKVMKPKVLRSWCRQILKGLLFLH
TRTPPIIHRDLKCDNIFITGPTGSVKIGDLGLATLKRASFAKSVIGTPEFMAPEMYEEHY
DESVDVYAFGMCMLEMATSEYPYSECQNAAQIYRKVTCGIKPASFEKVHDPEIKEIIGEC
ICKNKEERYEIKDLLSHAFFAEDTGVRVELAEEDHGRKSSIALRLWVEDPKKLKGKPKDN
GAIEFTFDLEKETPDGVAQEMIESGFFHESDVKIVAKSIRDRVALIQWRRERIWPALQPP
EQRDPGSPDKARGPPAPLQVQVTYHAKAGPPEPEEPEADQHLLPAALPASATSLASDSTF
DSGQGSTVYSDSQSSQQSAVLGSLADAAPPPTQCVCSPPVSASDGPVLPYSLPSLGPYQQ
PAVPGLPGSSIPPPARPPLPQQHFPEPAISFAPVSTGPGQPVPAGQQPPPLAQPAPLPPV
LAPPPVGPLQPVPPHLPPYLAPTSQVVAPAQLKPLQMPPAPLQPLPQVPAQVPPLPVGPP
IAPLASMDSLSTALPDLPAATGPAVPSIPAPSQYFSPAVILPSLPLSAAAAPLPASPALP
LQAVKLPHPTGAPLAVPCRTIVPNVAATATAIPLLAVAPQGVAALSIHPAAVAQLPAQPV
YPAAFPQMVPGDVPPSPLHAAQNVRAAPSQPAPPTLPQPHQPSITHLPEQAAAAGGAGSQ
ILLGHPPPYAVDVTAQVPTAPVPAAILSPPLPEVLPPPVPELPQLPSSLAPVVVAASQNL
PVQTTPLLPPTSHPPPPTGLGVASPCPAVQLTVEPAPEEQSSQEKQPSAPQSCDSYGGSD
VPSGREMSDSCEGAFGGGRLEGRAARKHHRRSTRARSRQERASRPRLTILNVCNTGDKMV
ECQLETHNHKMVTFKFDLDGDAPDEIATYMVEHDFILQAERETFIEQMKDVMDKAEDMLS
EDADVDRGSDPGVSPPHLSTCGLGTGEESRQSQANAPVYQQNVLHTGKRWFIICPVAEHP
AAEAPEPSPPLPLSSVQPEASQDTAPCKDQLSLKEKSGFPASPQHLSQTGPRDTPGGAPA
PLLPSSPPVTALPQDAATPAASPKPEPSVGTAVQAGGPGTSQGMASERETPQPLAETQDT
QLSAQPLGAGGGPCAPPLEAPRYPSGLGEPTSAREAMAQGEPLQAPAPAPSAPSGTPQPT
LGQPLPPLPPAVGAISLATPQLPSPPLGPTGAPQPPSALESDGEGPPPRVGFVDSTIKSL
DEKLRTLLYQEHVPTSSASAGTPVEAGDRDLTLEPQPVPGKSETAPGLGAALEQAGSSPL
TAESSLSQVTTSGLPPAPGAPQDAPASAFPALLEPADQSSGVPGETSARPTLGMQTEDSR
ASHLQTQGTLAAGSPQKHPGQQDGSSPAKTVGRFSVVSTQDEWTLGSPHSLRYSAPPDVY
LEEAPHSPDMKLAVRRAQTASSIEVGVGEPVSSDSGDEGPRRRPPVQKHASLPSSSGVAS
DFVKKATAFLHRSPRAGSPGPETPGRVGVKVPTISVTSFHSQSSYISSDNDSEIEDADIR
KELQSLREKHLKEISELQSQQKQEIEALYRRLGKPLPPNLGLFHTAPPAGRRRKSRSKLK
AGKLLNPLVQQLKVVASSTGHLSDCSRAPPAKDPAQAGAGPEAASDPCGKAVQTQQPCSV
RASLSADICSGLATDGGGAHGSGWTVYHPTSERLTYKSSSKPRARFLSGPVSVSIWSALK
RLCLGKEHSSRSSTSSLVPGPEPGPQPTLHVQAQANNSNNKRGTFTDDLHKLVDDWTSKT
VGTTQLKPSLNQLKQTQRLHGMEAPAGWSPATSETRAMNASRAAVGTPCLAPAPSPLSTA
AIPGTTPGLPMPDSESEKPD
NT seq
6543 nt
NT seq
+upstream
nt +downstream
nt
atgtccctgatgagtgtgaaaatctcaggtgccgtggtccatgttcaccggggcagcttt
ggcagtgactttgtagaacacaagtcctgtcagcctccaccagaggagctgcgtgatgac
acagccgtgtggcctgcttgggtcccagcccgggaagcaagcctgcatgagccagcagcc
agcggggcgttccggagcccgagggggccgggagcgccgcggccgccaccacaagccggc
ccgcaggtggccgcgcgcgcacacggccaggtgggcgtgccaggccccgccctccccgcg
cgccggcaaggggcgggcagccgaggccccgccctccccgcgcgccgggtcggagccggt
gcccgagcgcagcagagccgagccggagcagcacgcgggagcgcggtcccgcagcgggcc
ggcagagagagcagcgccgagacccggccccgagcgaggaccccggcctccagcacgact
cggcccccccggcctccggcgaggaccccggccccggagagcggcctcgcccgcctcgcg
cgccccggccgccgggccgcgggcatggacggcgcccgctcgccctgtgagtgccgagcc
ccccgcccgccgcctttgtgtgcgcgccgcgccgccgcagccccctccccgcgcgcccct
cctgcgccccgggccgcgtcctttgtggagccgccgcccggccgctggggggacggccgc
ttcctcaagttcgacatcgaactgggccgcggctcattcaagacggtctacaaggggctg
gacacggagacctgggtggaggtggcctggtgcgagctgcaggaccggaagctcaccaag
ctggagaggcagcggttcaaagaggaggccgagatgctcaagggcctgcagcaccccaac
atcgtgcgcttctatgacttctgggagtccagtgccagggggaagaggtgcatcgtgctg
gtgaccgagctgatgacctcggggacgctgaagacgtacctgaagcggttcaaggtgatg
aagcccaaggtcctgcgcagctggtgccggcagatcctgaaggggctgctgttcctgcac
accaggacgccccccatcatccaccgggacctcaagtgtgacaacatcttcatcactggg
cccaccggctctgtgaagatcggcgacttgggcctggccactctcaagagggcgtccttt
gccaagagcgtgatcggcaccccagagttcatggcgcccgagatgtacgaggagcattac
gacgagtctgtggacgtctatgccttcgggatgtgcatgctggagatggccacctcagag
tacccctactccgagtgccagaatgcagcccagatctaccggaaggtcacctgtggcatc
aagcctgccagctttgagaaagtgcatgatcctgaaatcaaggagatcatcggggaatgc
atctgcaaaaacaaggaggaaaggtacgagatcaaggacctgctgagccacgccttcttc
gcggaggacacgggagtgagggtggagctggcagaggaggaccacggcaggaagtctagc
atcgccctgcggctctgggttgaggaccccaagaaactgaagggcaagcccaaggacaac
ggggccatagagttcacctttgacctggagaaggagacgccggatggtgtggcgcaggag
atgatcgagtcgggattcttccacgagagcgacgtgaagattgtggccaagtccatccgc
gaccgagtagcattgatccagtggcggcgagagaggatctggccggcgctgcagcccccg
gagcagcgggacccaggcagccccgacaaggccaggggcccgcccgcacccctgcaggtc
caggtgacctaccacgccaaggctgggccgccggagcccgaggaacccgaggcagaccag
cacctcctgcctgccgcgctgccggccagcgccacctccctggcctcggatagcacgttc
gacagcggccagggctccaccgtgtactcggactctcagagcagccagcagagtgcggtg
ctgggctcgctggcggacgcggccccgcccccgactcagtgcgtgtgcagtcccccggtg
agcgcgagtgacgggcctgtcctgccgtacagcctgccctcgctggggccctaccagcag
cctgccgtgcctggactgccggggagctccatcccgcccccagcccgccctccgctcccg
cagcagcatttcccggagccagccataagttttgctcccgtgtcgacgggcccgggccag
cctgtgcctgctggccagcagcctcctccactggcccagccggcgcccttgccccctgtc
ctggccccaccgcccgtgggccccctccagccggtgccccctcatctgcctccctaccta
gctccgacttcccaggtggtggcccccgctcagctgaagcccctccagatgccgccagca
cctctgcagcctctgcctcaggtgcctgctcaggtgcctccgcttcccgtcgggccgccc
attgcgcccctggcctccatggacagcctctccacagctctgcccgacctgccggccgcc
accgggcccgccgtcccctccatccccgctccctctcagtatttctctcccgccgtcatc
ttgccaagcctcccgctcagcgccgccgccgcccccctgcccgcgtcaccagccctgccc
ctgcaggcggtcaagctgccccaccccaccggggcgccgctcgccgtgccgtgccggacc
attgtgccaaacgtggcggccaccgccaccgccatccctctgctggccgtggccccgcag
ggtgtggccgccctgtccattcacccggccgctgtggctcagctcccggcccagcccgtg
tacccggcagcctttccgcagatggtgcccggcgacgtcccgccttctcccctccacgcg
gcgcagaacgtgcgggctgccccgtcccagcctgcgccccccacgctgccgcagccccac
cagccaagcatcacacaccttccagagcaggccgctgcggcaggtggggcggggagccag
atcttgcttggccacccgcctccatacgctgtggatgtcaccgcccaggtccccacggca
cccgtgccagccgccatcctctccccacctctgcccgaagtgttgccgcctcctgtccct
gagctgcctcagctccccagctccctggcccccgtggtggtggcggcctctcagaacttg
cctgtccagaccacgccgctcctgccgcccacctcccacccaccaccacccaccgggctc
ggggtcgccagcccctgcccggctgtgcagctgacggtggagccggccccggaggagcag
tcctctcaggagaagcagcccagcgccccgcagagctgtgacagctacggaggctccgac
gttccctctggaagagagatgagcgacagctgtgagggtgcatttggtggtgggaggctg
gagggcagggccgcccggaaacatcaccgccggtccacgcgtgcgcgctcccgccaggag
agagccagccgcccccggctcaccatcctgaacgtgtgcaacacgggcgacaagatggtg
gagtgccagctggagacgcacaatcacaagatggtgacgttcaagtttgacctagacggg
gacgcgcctgacgagatcgccacctatatggtggagcacgacttcatcctgcaggccgag
cgagagacgttcatcgagcagatgaaggacgtcatggacaaggcggaggatatgctcagt
gaggacgcggacgtcgaccggggctccgaccccggggtcagcccgccgcacctcagcacc
tgcggcctgggcactggggaggagagtcgccagtcccaagcaaacgcccccgtgtatcag
cagaacgttctgcacacgggcaagaggtggtttatcatctgcccggtggctgagcaccca
gcggcggaggcccctgagccttcaccgccacttcctctgagctccgtgcagccagaagcc
agccaagacacagcgccctgtaaagaccagctgtccttaaaggaaaaatccggcttccca
gccagtccacagcatctgagccaaacaggccccagggacacccctggcggtgcaccggcc
cctttgctgccatcctcccctcctgtgactgctctgccccaggatgcggccaccccagcc
gccagccccaagccagagccctcagtggggactgctgtgcaggcagggggcccagggacc
tctcaggggatggccagtgagcgtgagaccccccagccactggcagagactcaagacacc
cagctttctgcacaacccctgggtgcaggtggggggccttgtgccccacctctggaggcc
ccccgctacccctcgggtttgggagagcccacctcagccagggaggccatggcccagggt
gagcccttgcaggctccagcccctgcacccagcgcccccagtgggacccctcagcccacc
ctgggtcagcccctacccccgttgccccctgcagtaggggccatcagcctggccactccc
cagctccctagccccccactggggcccactggggccccccagccaccctcggccttggag
tcagatggggaggggcctccccccagggtgggctttgtggacagcaccatcaagagccta
gatgagaagcttcgaactctgctctaccaggagcacgtgcccacctcctcagcctctgcc
gggacccctgtggaggcgggggaccgagacttgaccctggagccccagcccgtgccggga
aagtcagaaacagcccctgggctgggggctgcattggagcaggctgggtcctcgccattg
acagcagaatcatctttgagccaagtgacaacctcaggtttgcccccggcgccaggtgcc
ccccaggatgcccctgcttctgccttccctgcactcctggagcccgcagaccagagcagt
ggggtcccgggggaaacttcagccaggcccacactggggatgcagacggaagacagccgg
gccagccacctgcagacgcagggcactctggccgcagggtccccacagaagcatccaggg
cagcaggacggcagctcaccagccaaaactgtgggccggttctcggtggtcagcacgcag
gacgagtggaccctgggctccccccacagcctgcggtactcggcgccgccagacgtgtac
ctggaggaggccccccacagccccgacatgaagctggccgtgcggagggcgcagacagcc
tcctccatcgaggtcggcgtgggcgagccggtgtccagcgactccggggacgagggtccg
cgcaggcggccccctgtgcagaagcacgcctccctacccagcagcagtggtgtggccagc
gacttcgtgaagaaggccaccgccttcctgcacaggtccccacgggctggctccccgggc
ccggagacgcccggcagagtgggcgtgaaggtgcccaccatcagtgtgacctccttccac
tcccagtcgtcctacatcagcagcgacaacgactcggagatcgaggacgccgatatcagg
aaggagctgcagagtctgcgggagaagcacctgaaggagatctcggagctgcagagccag
cagaagcaggagatcgaggccctgtaccgccgcctgggcaagccgctgccccccaacctg
ggcctcttccacacggcccctcccgccggccgcaggaggaagagcaggagcaagctgaag
gcagggaagctgctcaacccgctggtgcagcagctcaaggtcgtggcctccagcacaggt
cacttgtcagactgcagcagagcccctcctgctaaggaccctgcccaagccggggcaggg
cccgaagcagcttcagacccgtgtgggaaggcagttcagacccagcagccttgctcggtg
cgggcctccctgtctgcagacatctgctccggcttagccactgacggaggcggagcgcat
ggctcaggctggacggtttaccacccaacgtctgagagactgacctataagtctagtagc
aaacctcgcgctcgattcctcagtggacccgtgtctgtgtccatctggtctgccctgaag
cgtctctgtctaggcaaagagcacagcagtcggtcttccaccagcagcctggtcccgggc
cctgagccgggcccccagcccaccttgcacgtccaggcacaggcgaacaacagcaacaac
aagagaggcaccttcacggatgacctgcacaagctggtggacgactggacgagcaagacg
gtggggaccacccagctgaagccctcgctcaaccagctgaagcagactcagaggctacac
ggcatggaggccccggcgggctggtccccagccactagcgagacacgggctatgaacgcc
tctcgagcagcagtggggacaccatgtctggccccagcgcccagccctctatccaccgcg
gccattcctggaaccaccccaggcctgcccatgccagattctgagagtgagaagcccgac
tga
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