Panthera uncia (snow leopard): 125925106
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Entry
125925106 CDS
T08832
Name
(RefSeq) fumarate hydratase, mitochondrial
KO
K01679
fumarate hydratase, class II [EC:
4.2.1.2
]
Organism
puc
Panthera uncia (snow leopard)
Pathway
puc00020
Citrate cycle (TCA cycle)
puc00620
Pyruvate metabolism
puc01100
Metabolic pathways
puc01200
Carbon metabolism
puc04934
Cushing syndrome
puc05200
Pathways in cancer
puc05211
Renal cell carcinoma
Module
puc_M00009
Citrate cycle (TCA cycle, Krebs cycle)
puc_M00011
Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
Brite
KEGG Orthology (KO) [BR:
puc00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
125925106
00620 Pyruvate metabolism
125925106
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
125925106
09162 Cancer: specific types
05211 Renal cell carcinoma
125925106
09167 Endocrine and metabolic disease
04934 Cushing syndrome
125925106
Enzymes [BR:
puc01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.2 fumarate hydratase
125925106
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Gene cluster
GFIT
Motif
Pfam:
Lyase_1
FumaraseC_C
Motif
Other DBs
NCBI-GeneID:
125925106
NCBI-ProteinID:
XP_049489819
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All DBs
Position
F1:7972576..8003303
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AA seq
508 aa
AA seq
DB search
MYRVVRLLARSRRLVRPPGSASAPGLGGVPVLPLRALNAAGMASQNSFRIEFDTFGELKV
PNDKYYGAQTVRSTMNFKIGGVTERMPIPVIKAFGILKRAAAEVNQDYGLDSKIANAIMK
AADEVAEGKLNDHFPLVVWQTGSGTQTNMNVNEVISNRAIEMLGGELGSKKPVHPNDHVN
KSQSSNDTFPTAMHIAAAVEVHEVLLPGLQKLHDALEAKSKEFAQIIKIGRTHTQDAVPL
TLGQEFSGYVQQVKYAMTRIKAAMPRIYELAAGGTAVGTGLNTRIGFAEKVAAKVAALTG
LPFVTAANKFEALAAHDALVELSGAMNTTACSLMKIANDIRFLGSGPRSGLGELILPENE
PGSSIMPGKVNPTQCEALTMVAAQVMGNHVAVTVGGSNGHFELNVFKPMMIKNVLHSARL
LGDACVSFTENCVVGIQANTERINKLMNESLMLVTALNPHIGYDKAAKIAKTAHKNGSTL
KATAIELGYLTAEQFDEWVKPKDMLGPK
NT seq
1527 nt
NT seq
+upstream
nt +downstream
nt
atgtaccgcgtcgtccgactcctcgcgcgctcgcgtcgcctcgtgcggcctcccggctca
gcctcagctcccggcctcggaggcgtgccggtcctcccactgcgggccctgaacgccgct
ggaatggcaagccaaaattcctttcggatagagtttgatacttttggtgaactcaaggtc
ccaaatgataagtattatggcgcccagactgtgagatccacgatgaactttaaaattgga
ggtgtgacggagcgcatgccaatcccagttattaaagcttttggaatcttgaagcgagcg
gctgctgaagtaaaccaggattatggtcttgattcgaagattgctaatgcgataatgaag
gcagccgatgaggtagctgaaggtaaattaaatgatcattttccacttgtggtatggcag
actggatcaggaacccagacaaatatgaatgtaaatgaagtcattagcaatagagcaatt
gaaatgctgggaggtgaacttggtagcaagaaacctgtgcatcccaatgatcacgttaat
aaaagccagagttcgaatgatacctttcccacagcgatgcacattgctgctgctgtagaa
gttcatgaggtgctcctgccagggctacagaagctgcatgatgctctcgaagccaaatcc
aaagagtttgcccagatcatcaaaattgggcgcactcacacccaggacgctgttccactc
actcttgggcaggaatttagtggttatgttcaacaagtgaaatatgcaatgacgagaata
aaagccgccatgccaagaatctatgagctcgcagctggaggcactgctgttggtactggt
ttaaatactagaattggctttgcagaaaaggttgctgcaaaagtggctgcactcacaggg
ttgccttttgtcacagctgcaaataaatttgaagctctggctgctcatgatgctttggtt
gaactcagtggagccatgaatactaccgcctgcagtctgatgaagatagcaaacgatatt
cgttttctgggttctggtcctcgctcaggtctgggagagctgatcttgcctgaaaatgag
ccaggaagtagtatcatgccaggcaaggtgaaccctacgcagtgtgaagcgctcaccatg
gttgcagcccaggtcatggggaatcacgtcgccgttaccgttggaggcagcaatggacat
tttgagttgaatgttttcaagccaatgatgattaaaaatgtgttacactcagccaggctg
ctgggggacgcgtgcgtttccttcacagaaaactgcgttgtgggaatccaggccaacaca
gagaggatcaacaagctgatgaacgaatctctaatgttggtgacagctcttaatcctcat
atagggtatgacaaggcagcaaagattgctaagacagcacacaaaaatggatcaacctta
aaggccactgccattgagcttggctatctcacagcagagcagtttgatgagtgggtaaaa
cctaaggacatgctgggtccaaagtga
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