KEGG   Panthera uncia (snow leopard): 125925380
Entry
125925380         CDS       T08832                                 
Name
(RefSeq) voltage-dependent L-type calcium channel subunit alpha-1S
  KO
K04857  voltage-dependent calcium channel L type alpha-1S
Organism
puc  Panthera uncia (snow leopard)
Pathway
puc04010  MAPK signaling pathway
puc04020  Calcium signaling pathway
puc04022  cGMP-PKG signaling pathway
puc04024  cAMP signaling pathway
puc04260  Cardiac muscle contraction
puc04261  Adrenergic signaling in cardiomyocytes
puc04270  Vascular smooth muscle contraction
puc04723  Retrograde endocannabinoid signaling
puc04725  Cholinergic synapse
puc04726  Serotonergic synapse
puc04727  GABAergic synapse
puc04911  Insulin secretion
puc04912  GnRH signaling pathway
puc04921  Oxytocin signaling pathway
puc04924  Renin secretion
puc04925  Aldosterone synthesis and secretion
puc04927  Cortisol synthesis and secretion
puc04929  GnRH secretion
puc04934  Cushing syndrome
puc04935  Growth hormone synthesis, secretion and action
puc05010  Alzheimer disease
puc05020  Prion disease
puc05022  Pathways of neurodegeneration - multiple diseases
puc05207  Chemical carcinogenesis - receptor activation
puc05410  Hypertrophic cardiomyopathy
puc05412  Arrhythmogenic right ventricular cardiomyopathy
puc05414  Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:puc00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    125925380
   04020 Calcium signaling pathway
    125925380
   04024 cAMP signaling pathway
    125925380
   04022 cGMP-PKG signaling pathway
    125925380
 09150 Organismal Systems
  09152 Endocrine system
   04911 Insulin secretion
    125925380
   04929 GnRH secretion
    125925380
   04912 GnRH signaling pathway
    125925380
   04921 Oxytocin signaling pathway
    125925380
   04935 Growth hormone synthesis, secretion and action
    125925380
   04924 Renin secretion
    125925380
   04925 Aldosterone synthesis and secretion
    125925380
   04927 Cortisol synthesis and secretion
    125925380
  09153 Circulatory system
   04260 Cardiac muscle contraction
    125925380
   04261 Adrenergic signaling in cardiomyocytes
    125925380
   04270 Vascular smooth muscle contraction
    125925380
  09156 Nervous system
   04727 GABAergic synapse
    125925380
   04725 Cholinergic synapse
    125925380
   04726 Serotonergic synapse
    125925380
   04723 Retrograde endocannabinoid signaling
    125925380
 09160 Human Diseases
  09161 Cancer: overview
   05207 Chemical carcinogenesis - receptor activation
    125925380
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    125925380
   05020 Prion disease
    125925380
   05022 Pathways of neurodegeneration - multiple diseases
    125925380
  09166 Cardiovascular disease
   05410 Hypertrophic cardiomyopathy
    125925380
   05412 Arrhythmogenic right ventricular cardiomyopathy
    125925380
   05414 Dilated cardiomyopathy
    125925380
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    125925380
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04040 Ion channels [BR:puc04040]
    125925380
Ion channels [BR:puc04040]
 Voltage-gated cation channels
  Calcium channel, voltage-gated (Cav)
   125925380
SSDB
Motif
Pfam: Ion_trans Ca_chan_IQ GPHH PKD_channel CAC1F_C
Other DBs
NCBI-GeneID: 125925380
NCBI-ProteinID: XP_049490282
LinkDB
Position
F1:complement(38655955..38721357)
AA seq 1871 aa
MEPSSPQDEGLRKKQPKKPVPEILPRPPRALFCLTLQNPLRKACINIVEWKPFETIILLT
IFANCVALAVYLPMPEDDNNTLNLGLEKLEYFFLIVFSIEAAMKIIAYGFLFHQDAYLRS
GWNVLDFIIVFLGVFTVILEQVNVIQSNTAPMSSKGAGLDVKALRAFRVLRPLRLVSGVP
SLQVVLNSIFKAMLPLFHIALLVLFMVIIYAIIGLELFKGKMHKTCYFIGTDIVATVENE
KPSPCARTGSGRPCTINGSECRGGWPGPNHGITHFDNFGFSMLTVYQCITMEGWTDVLYW
VNDAIGNEWPWIYFVTLILLGSFFILNLVLGVLSGEFTKEREKAKSRGTFQKLREKQQLE
EDLRGYMSWITQGEVMDVEDLREGKLSLDEGGSDTESLYEIEGLNKIIQFVRHWRQWNRI
FRWKCHDVIKSRVFYWLVILVVALNTLSIASEHHNQPLWLTHLQDVANRVLLALFAVEML
LKMCGLGLRQYFMSIFNRFDCFVVCSGVLELLLVESGAMTPLGISVLRCIRLLRIFKITK
YWTSLSNLVASLLNSIRSIASLLLLLFLFIIIFALLGMQLFGGRYDFEDTEVRRSNFDNF
PQALISVFQVLTGEDWNSVMYNGIMAYGGPSYPGVLVCIYFIILFVCGNYILLNVFLAIA
VDNLAEAESLTSAQKAKAEERKRRKMSKGLPDKSEEEKSVMAKKLEQKPKGEGIPTTAKL
KIDEFESNVNEVKDPYPSADFPGDDEEDEPEIPVSPRPRPLAELQLKEKAVPIPEASSFF
IFSPTNKIRVLCHRIVNATWFTNFILLFILLSSAALAAEDPIRAESVRNQILGYFDIAFT
SVFTVEIVLKMTTYGAFLHKGSFCRNYFNILDLLVVAVSLISMGLESSAISVVKILRVLR
VLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVLVTTLLQFMFACIGVQLFKGKFFSCNDL
SKMTEKECRGYYYVYKDGDPTQMELRPCQWIHSDFHFDNVLSAMMSLFTVSTFEGWPQLL
YQAIDSYKEDTGPVYNNRVEMAIFFIIYIILIAFFMMNIFVGFVIVTFQEQGETEYKNCE
LDKNQRQCVQYALKARPLRCYIPKNPYQYRVWYVVTSSYFEYLMFALIMLNTICLGMQHY
NQSEEMNHISDILNVAFTIIFTLEMVLKLMAFKARGYFGDPWNVFDFLIVIGSIIDVILS
EIDTFLASSGGLYCLGGGCGNVDPDESARISSAFFRLFRVMRLIKLLSRAEGVRTLLWTF
IKSFQALPYVALLIVMLFFIYAVIGMQMFGKIAMVDGTQINRNNNFQTFPQAVLLLFRCA
TGEAWQEILLACSYGKLCDPESDYAPGEEYTCGTNFAYYYFVSFYMLCAFLIINLFVAVI
MDNFDYLTRDWSILGPHHLDEFKAIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKFCP
HRVACKRLVGMNMPLNSDGTVTFNATLFALVRTALKIKTEGNFEQANEELRAIIKKIWKR
TSMKLLDQVIPPIGDDEVTVGKFYATFLIQEHFRKFMKRQEEYYGYRPKKDTIQIQAGLR
TIEEEAAPEIRRTISGDLTAEEELERAMVEAAMEEGIFRRTGGLFGQVDNFMERTNSLPP
VMANQRPLQFAEIEMEELESPVFLEDFPQDPRTNPLAHANTNNANANVACDNSSHSNSQL
FSSIRYEREFPGETETPAARGGAFGQPRSVLGAHSKSCVEKLKGQLAQREMPGAQASPTL
CQHAGAEPPLPGERRDPAPGPEEASHHGRTKESSSRCQTPATARLIQEALVRGGLDTLAA
DADFVTVTGRALADACQMEPEDVEVAATELLKRQESPEGMASAQGRLSLRSSLASLDQHQ
GSQETLMPRRL
NT seq 5616 nt   +upstreamnt  +downstreamnt
atggagccatcctcaccccaggatgagggcctgaggaagaaacagcccaagaagcccgtt
cctgagattctgccaaggccaccccgggccttgttctgcttgaccctccagaaccccctg
aggaaggcctgcatcaacatcgtggaatggaaacccttcgagacaatcatcttgctcacc
atctttgccaactgtgtggccctggctgtgtacctgcccatgcctgaagatgacaacaac
actctcaaccttggtctggagaaactggagtatttcttcctcatcgtcttctcaatcgaa
gccgccatgaagatcattgcctatggcttcctgttccaccaggatgcctacctgcgcagc
ggctggaatgtgctagacttcatcatcgtcttcctgggggttttcaccgtgattctggaa
caggttaacgtcatccaaagcaacactgccccgatgagcagcaaaggggctggcctggac
gtcaaggccctgagagccttccgtgtgctcagacccctccggcttgtgtcgggggtgccg
agcctgcaggtggtcctcaactccatcttcaaggccatgcttcccctgttccacatcgcc
ctgctcgtcctctttatggtcatcatctatgccatcatcgggctggagctcttcaagggc
aaaatgcacaagacctgctacttcattgggacagatatcgtggccacggtagagaacgag
aagccctcaccctgcgccaggacgggctcgggacgcccgtgcaccatcaacggcagcgag
tgtcggggcggctggccggggcccaaccacggcatcacgcactttgacaactttggcttc
tccatgctcaccgtgtaccagtgcatcaccatggaggggtggaccgatgtcctctactgg
gtcaatgatgccatcgggaacgagtggccctggatctattttgtcaccctcattctgctg
ggatccttcttcattctcaacctggtgctgggtgtcctgagcggggaattcactaaggag
cgggagaaggccaagtccaggggaaccttccaaaagctccgggagaagcagcagctggaa
gaggacctccggggctacatgagctggatcacgcagggcgaggtcatggacgttgaggac
ttgagagaagggaagctgtctctggatgaaggaggctctgacacggagagcctgtatgaa
atcgagggcttgaacaaaatcatccagtttgtccgccactggaggcagtggaaccgcatc
tttcgctggaagtgccacgatgtgatcaagtccagagtcttctattggctggtgatcctg
gtcgttgccctcaacaccctgtctatcgcctcagagcaccacaaccagcctctctggttg
acccatttgcaagacgttgccaaccgcgtgctgctggccctcttcgccgtcgagatgctg
ctgaagatgtgcgggctgggcctgcgccagtatttcatgtccatcttcaaccgcttcgac
tgcttcgtggtgtgcagcggcgtcctggagctgctgctggtggagtcaggtgccatgacg
cccctgggcatctccgtgctgcgctgcatccgcctcctgcggatcttcaagatcaccaag
tactggacgtcgctgagcaacctggtggcatccctgctcaactccatccgctccatcgcc
tccctgctgctgctgcttttcctcttcatcatcatcttcgccctgctgggcatgcagctc
ttcgggggcaggtacgacttcgaggacacggaggtgcggcgcagcaactttgacaacttc
ccgcaggccctcatcagcgtcttccaggtcctaacaggtgaagactggaattctgtgatg
tacaacgggatcatggcctacggcgggccgtcctaccctggggtgctcgtgtgcatttat
ttcatcatcctttttgtctgtggcaattatatcctgctcaatgtcttcctggccatcgct
gtggacaacctggctgaggcagagagcctgacttctgcccagaaggccaaagctgaggag
agaaaacgcaggaagatgtccaagggtcttccagataagtcagaggaagagaagtcagtg
atggccaagaagctggaacagaaacccaagggtgaaggcatccctaccaccgccaagctg
aaaatcgatgaatttgaatctaatgtcaatgaagtgaaggatccctacccctcagctgac
ttcccaggagatgatgaggaagatgagcccgagatcccagtgagcccccgaccacgcccg
ctggctgagctgcagctcaaagagaaggcagtgcccatcccagaagccagctccttcttc
attttcagccccaccaacaagatccgtgtcttgtgtcatcgcattgtcaacgctacctgg
ttcaccaacttcatccttcttttcatcctgctcagcagtgccgcactggccgcggaggac
cccatccgggccgagtccgtgaggaatcagatccttgggtatttcgacattgcattcacc
tctgtcttcactgtggagattgtcctcaagatgacgacctacggtgccttcctgcacaag
ggctccttctgccgcaactacttcaacatcctggacctgctggtggtggccgtgtccctc
atctccatgggactcgagtccagcgccatctccgtggtgaaaatcctgagggtgctgagg
gtgctccggcccctgcgggccatcaacagagccaaggggctgaagcacgtggtgcagtgt
gtgtttgtggccatccgcacaatcgggaacatcgtcctcgtcaccaccctcctgcagttc
atgtttgcctgcatcggcgtccagcttttcaaggggaagttcttcagctgtaatgactta
tccaagatgacagagaaggagtgcaggggctattactatgtgtacaaggatggggacccc
acgcagatggagctgcgcccctgccagtggatacacagcgacttccatttcgacaacgtg
ctctcggccatgatgtcactcttcacggtctccacctttgagggatggcctcagctgctt
taccaggccatagactcatacaaggaagacacaggccccgtctacaacaaccgggtggag
atggccatcttcttcatcatctacatcatcctcattgccttcttcatgatgaacatcttt
gtgggcttcgttattgtcaccttccaggagcagggggagactgagtacaagaactgtgaa
ctggacaagaaccagcgccagtgtgtgcaatatgccctgaaggcccgcccgctgaggtgc
tacatccccaaaaacccataccagtaccgggtgtggtatgtcgtcacctcctcctacttt
gagtacctgatgtttgccctcatcatgctcaacaccatctgcctgggcatgcagcactac
aaccagtcagaggagatgaaccacatctcagacatcctcaacgtggccttcaccatcatc
ttcaccctggagatggtcctcaagctcatggcgttcaaggccaggggctattttggagac
ccctggaatgtgtttgacttcttgattgtcatcggcagcatcatcgatgtcattctcagt
gaaattgacactttcctggcctccagcgggggactgtattgcctgggtggaggctgcggg
aacgttgacccagacgagagcgcccgcatctccagcgccttctttcgcctgttccgggtc
atgaggctgatcaagctgctgagccgggcagagggagtgcgcactctgctgtggacgttc
atcaagtccttccaggccctgccatacgtggccctgctcatcgtcatgctcttcttcatc
tacgccgtcatcggcatgcagatgtttggtaagatcgccatggtggacgggacccaaata
aaccggaacaacaacttccagaccttcccacaagctgtgttgctgctcttcaggtgtgcg
acaggtgaggcgtggcaggagatcctcctggcctgcagctacggcaagttgtgtgacccc
gaatcggattatgccccgggtgaggagtacacgtgtggcaccaacttcgcctactattac
ttcgtcagcttctacatgctctgcgccttcctgatcatcaacctgtttgtagctgtcatc
atggacaactttgactacctcacccgggactggtccatcctgggcccccatcacctggat
gagttcaaagccatttgggcagagtatgacccggaggctaagggcagaatcaaacacctg
gatgtggtgaccctgctgagacggatccaaccccctctgggctttgggaagttctgccca
caccgggtagcatgtaagcggctggtgggcatgaacatgcccttgaacagcgacggcacg
gtcaccttcaacgccactctcttcgccctggtccgcacagcactcaagatcaagacggaa
ggtaactttgagcaggccaatgaggagctgagggccatcatcaagaagatctggaagaga
accagcatgaagctcctggaccaggtcattcctccaataggagatgatgaggtgactgta
gggaagttctacgccacgtttctcatccaggagcacttccggaagttcatgaagcgccag
gaagagtattatgggtatcggcccaagaaggacactatacaaatccaggccggactgagg
accattgaggaagaggcagccccagagatccggcgcaccatctcaggagacctgacagct
gaagaggagctggagagagccatggtggaggctgcgatggaggaagggatattccggagg
actgggggcctgtttggccaggtggacaacttcatggaaaggaccaactccttgccccct
gtgatggccaaccagagacccctccagtttgctgagatagagatggaagagctggaatca
cccgtcttcttggaggatttccctcaagatccacgcaccaaccctcttgctcatgccaac
accaataatgccaatgccaatgttgcctgtgacaacagcagccatagcaacagccagcta
ttttccagcatccgctatgaaagggagttccctggagagacagagacgcctgctgccaga
ggaggagcctttggccagccccgaagcgtcctgggagcccacagcaaatcctgtgtggaa
aagttaaaaggacagctggcccagagagaaatgcccggggcccaggcgtctcctaccctc
tgccagcatgccggcgcagagcctcccctgcctggggagaggagggaccccgccccgggg
cctgaggaagcatcccaccacggtaggaccaaggagagtagttccaggtgccagactcca
gcaacagcccggctgatacaggaggctctggttcgaggaggcctggacaccttggcggct
gatgctgactttgtcacggtgacaggccgggccctggcagatgcctgccagatggaacca
gaggatgtggaggtggcagcgacagagctgctgaaaagacaagagtccccagagggcatg
gccagtgcccagggacgcttgagcctcaggtcctcgctggcgagccttgaccagcatcag
ggctcccaggagaccctgatgccccgcaggctgtga

DBGET integrated database retrieval system