Panthera uncia (snow leopard): 125926504 Help Entry 125926504         CDS       T08832                                  Name (RefSeq) DNA topoisomerase 2-alpha   KO K03164   DNA topoisomerase II [EC:5.6.2.2] Organism puc  Panthera uncia (snow leopard) Pathway puc01524   Platinum drug resistance Brite KEGG Orthology (KO) [BR:puc00001]  09160 Human Diseases   09176 Drug resistance: antineoplastic    01524 Platinum drug resistance     125926504  09180 Brite Hierarchies   09182 Protein families: genetic information processing    03032 DNA replication proteins [BR:puc03032]     125926504    03036 Chromosome and associated proteins [BR:puc03036]     125926504 Enzymes [BR:puc01000]  5. Isomerases   5.6  Isomerases altering macromolecular conformation    5.6.2  Enzymes altering nucleic acid conformation     5.6.2.2  DNA topoisomerase (ATP-hydrolysing)      125926504 DNA replication proteins [BR:puc03032]  Eukaryotic type   DNA Topoisomerases    125926504 Chromosome and associated proteins [BR:puc03036]  Eukaryotic type   Chromosome condensation proteins    Other regulators of chromosome condensation     125926504   Centrosome formation proteins    Centriole proteins     125926504 BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  DNA_topoisoIV TOPRIM_C DNA_gyraseB DTHCT HATPase_c Toprim Microp_apicomplexa_20 Motif Other DBs NCBI-GeneID:  125926504 NCBI-ProteinID:  XP_049491966 LinkDB All DBs Position E1:complement(10500035..10528563) Genome browser AA seq 1534 aa AA seqDB search MEVSPLQPVNENMLINKTKKNEDAKKRLSIERIYQKKTQLEHILLRPDTYIGSVELVTQQ MWVYDEDIGINYREVTFVPGLYKIFDEILVNAADNKQRDPKMSCIKVTIDPENNLISIWN NGKGIPVVEHKVEKMYVPALIFGQLLTSSNYDDDEKKVTGGRNGYGAKLCNIFSTKFTVE TASREYKKMFKQTWMDNMGRAGEMELKPFNGEDYTCITFQPDLSKFKMQSLDKDIVALMV RRAYDIAGSTKDVKVFLNGNKLPVKGFRSYVDMYLKDKVDETGNPLKIIHEQVNPRWEVC LTMSEKGFQQISFVNSIATSKGGRHVDYIADQIVTKLVEVVKKKNKGGVAVKAHQVKNHM WIFVNALIENPTFDSQTKENMTLQVKSFGSTCHLSEKFIKAAIGCGIVESILNWVKFKAQ VQLNKKCSAVKHNRIKGIPKLDDANDAGGRNSNECTLILTEGDSAKTLAVSGLGVVGRDK YGVFPLRGKILNVREASHKQIMENAEINNIIKIVGLQYKKNYEDEDSLKTLRYGKIMIMT DQDQDGSHIKGLLINFIHHNWPSLLRHRFLEEFITPIVKVSKNKQEMAFYSLPEFEEWKS STPNHKKWKVKYYKGLGTSTSKEAKEYFADMKRHRIQFKYSGPEDDAAISLAFSKKQIDD RKEWLTHFMEDRRQRKLLGLPEDYLYGQTTTYLTYNDFINKELILFSNSDNERSIPSMVD GLKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSSYHHGEMSLMMTIINLAQNFVGSNN LNLLQPIGQFGTRLHGGKDSASPRYIFTMLSPLARLLFPPKDDHTLKFLYDDNQRVEPEW YIPIIPMVLINGAEGIGTGWSCKIPNFDIREVVNNIRRLMDGEEPLPMLPSYKNFRGTIE ELAPNQYVISGEVAILNSTTIEISELPIRTWTQTYKEQVLEPMLNGTEKTPPLITDYREY HTDTTVKFVVKMTEEKLAEAERVGLHKVFKLQTSLTCNSMVLFDHVGCLKKYDTVLDILR DFFELRLKYYGLRKEWLLGMLGAESAKLNNQARFILEKIDGKIIIENKPKKELIKVLIQR GYDSDPVKAWKEAQQKVPDEEENEESDNENEAEKGDSVKDSGPTFNYLLDMPLWYLTKEK KDELCKLRNEKEQELETLKRKSPSDLWKEDLAAFIEELEAVETKEKQEEQIGLPGKGGKA KGKKIQMAEVLPSPCGKRVIPRVTIEMKAEAEKKIKKKIKSENTEGSPQEDGMELEGLKQ RLEKKQKREPGTKTKKQTTLPFKPVKKGKKRNPWSDSESDMSSNESDFDVPPREIEPRRA ATKTKFTVDLDSDDDFSDFDEKTQDEDFVPSDVSPVKTKTSPPVPTNKELKPQKSATSVM DLDAGGAKDSVPPSLDSPAADFSAETEIINPVSKKKVAVKKTAAKSQSSTSTTGAKKRAA PKGTKKEPGLNSDVSQKPDPPKTKNRRKRKPSTSDDSDSNFEKMISKTVTSKKSKGESED FHLDLDSAVAPRAKSGRAKKPIKYLEESDEDDLF NT seq 4605 nt NT seq  +upstreamnt  +downstreamnt atggaggtgtcaccactgcagcctgtaaatgaaaatatgctaatcaacaaaacaaagaaa aatgaagatgctaagaaaagactgtctattgaaaggatctatcaaaagaaaacccaactg gaacatattttgctccgcccagacacctatattggctccgtggaattagtgacccagcaa atgtgggtttacgatgaagatattggcattaactacagggaagtcacctttgtccctggg ttgtacaaaatctttgatgagattctagtcaatgctgcagacaacaaacaaagggaccca aaaatgtcttgtattaaagtcacaattgacccggaaaacaatttaattagtatatggaat aatgggaaaggtattcctgttgttgaacacaaagttgagaagatgtacgtcccagctctc atctttggacagctcctaacttccagtaactatgatgatgatgaaaagaaagtaacaggt ggtcgaaatggctatggggccaaattgtgtaacatattcagtaccaaatttactgtggaa acagccagtagagaatacaagaaaatgttcaaacagacgtggatggataacatgggaagg gctggtgagatggaactcaagcccttcaatggggaagattatacatgtattaccttccag cctgatttgtccaagtttaaaatgcaaagcctagacaaagatattgttgcactaatggtc agaagagcatatgatattgccggatccactaaagatgtcaaagtgtttctcaatggaaat aagctgccagtaaaaggattccgtagctatgtagatatgtatttgaaggataaggtagat gaaactggcaatccgttgaaaattatccatgaacaagtaaaccccaggtgggaagtatgc ttaacaatgagtgaaaaaggctttcagcaaattagctttgtcaacagcattgctacttcc aagggtggcagacatgttgattatatagctgatcagattgtgactaaacttgttgaggtt gttaaaaagaagaacaagggtggtgttgcagtaaaagcacatcaggtgaaaaatcacatg tggatttttgtgaatgccttaattgaaaacccaacctttgattctcagacaaaagagaac atgactttacaagtcaagagctttggatcaacctgccatttaagtgaaaaattcatcaaa gctgcaattggttgtggtattgtagaaagcatactaaactgggtgaagtttaaggcccaa gtacagttaaacaagaagtgttcagctgtaaaacataacaggatcaagggaattcccaaa ctcgatgatgccaatgatgcagggggtcgaaattccaatgagtgtacacttatcctgact gagggagactcagctaaaactttggctgtttcaggccttggcgtggttgggagagacaaa tatggggttttcccgcttagaggaaaaatactcaatgttcgagaagcttctcataaacag atcatggaaaatgctgaaattaacaatatcatcaagattgtgggtcttcagtacaagaaa aactatgaagatgaagattcattgaagactcttcgttatgggaagataatgattatgaca gatcaggaccaagatggttcccatatcaaaggcttgctgattaattttatccatcacaac tggccctctcttctgcggcaccgttttctggaagaatttatcactcctattgtaaaggtg tctaaaaacaagcaagaaatggcattctatagccttcctgaatttgaagaatggaagagt tctacaccaaatcataaaaaatggaaagtcaagtactacaaaggtttgggcacgagcaca tcaaaagaggctaaggaatactttgcagatatgaaaagacatcgtattcaattcaaatat tccggtcctgaagatgatgctgccatcagcctggcctttagcaagaaacagatagatgat cgaaaggaatggttaactcatttcatggaggacagaaggcaacggaagttacttggcctt cctgaggattacttgtatggacaaactaccacatatctgacatataatgacttcataaac aaggaacttatcctgttctcaaattctgataacgagagatctattccatctatggtggat ggtttgaaaccaggtcaaagaaaggttttgtttacctgtttcaaacggaatgacaagcga gaggtgaaggttgctcagttagctgggtcagtggcagagatgtcctcttatcatcatggt gagatgtcactaatgatgaccattatcaatttggctcagaattttgtgggtagcaataat ctgaacctcttgcaacccattggtcagtttggtaccaggctgcatggtggtaaggattct gctagtcctcgatacatcttcacaatgctcagccctttggctcggttgttatttccacca aaagatgatcatacattaaagtttttatatgatgacaatcaacgtgttgaacctgaatgg tacatccctattatacccatggtgctgataaatggtgctgaaggaatcggtactgggtgg tcctgcaaaatcccgaactttgatattcgtgaagttgtaaataatatcaggcgtctgatg gatggagaagaacctttgccaatgcttccgagttacaagaacttcaggggtacgattgaa gagctggctccaaatcaatatgtgattagtggtgaagtggctattcttaattccacaacc attgaaatctcagaacttcccatcagaacatggacccaaacatataaagaacaggttcta gaacccatgttgaatggcactgagaagacaccacctctcataaccgattatagggaatac catacagacaccactgtgaagtttgttgtgaagatgactgaagagaaattggcagaggca gagagagtgggactacacaaagtcttcaaactccagactagtctcacatgcaactctatg gtgctttttgaccatgtaggatgtttaaagaaatatgacacagtgttggatattctaaga gacttctttgaactcaggcttaagtattatggattaagaaaagaatggctactaggaatg cttggtgctgaatctgctaaactgaacaatcaggctcgctttatcttagagaaaatagat ggcaaaataatcattgaaaataagccaaagaaggaattaattaaagttctgattcagagg ggttatgattctgatcctgtgaaggcttggaaagaagcccagcaaaaggtaccagatgaa gaagaaaatgaagagagtgacaatgaaaatgaagccgaaaagggtgactctgtaaaagat tctggaccaaccttcaactaccttcttgatatgcctctttggtatctcaccaaggaaaag aaggatgaactgtgcaagctgagaaatgaaaaagaacaagagctagaaacattaaagaga aagagtccatcagatttgtggaaagaagacctagctgcttttattgaagagctggaggct gttgaaacaaaggaaaaacaagaagaacaaataggactccctgggaaaggggggaaagca aaggggaaaaaaatacagatggctgaagttttgccttctccatgtgggaaaagagtcatc ccccgagtgaccatagagatgaaagcagaggcagaaaagaaaattaaaaagaaaattaag agtgaaaacactgaagggagccctcaagaggatggtatggaactagaaggtctgaaacaa aggttggagaagaaacagaaaagagagccaggtaccaagacaaagaagcaaactacgttg ccatttaaaccagtcaaaaaaggaaagaagagaaacccctggtctgattcagaatcagat atgagcagtaatgaaagtgactttgatgttcccccacgagagatagagccacggagagca gcaacaaaaaccaaatttacagtggatttggattcagatgatgatttctcagattttgat gaaaaaactcaagatgaggattttgtcccatcagatgttagcccagttaagaccaaaact tccccaccagtacctactaacaaagaactgaagccacagaagagtgccacatcagtaatg gaccttgatgctggtggtgccaaggacagtgtaccaccttctctagattctccggccgct gatttctcagctgaaactgaaatcataaaccctgtttctaaaaagaaggtagcggtgaag aagacagcagcaaaaagtcagtcttccacctccactacaggtgccaaaaaaagggctgca ccaaaaggaaccaaaaaggagccaggcttgaattctgatgtctctcaaaagcctgatcct cccaaaaccaaaaatcgccgcaaaaggaagccatccacttctgatgattctgactctaat tttgagaaaatgatttctaagacagtcacaagcaagaaatccaagggggagagtgaggat ttccatctggacttagactcagctgtggctcctcgggccaaatctggacgggcaaagaaa cctataaagtacctcgaagaatcagatgaagatgatctgttctaa

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